[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obstructive-defecation-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obstructive-defecation-syndrome":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100579512","phase-4-peg3350-vs-senna-after-urogyn-surgery-100579512",false,"NCT06825260","PEG3350 vs Senna After Urogyn Surgery","Polyethylene Glycol 3350 Compared With Senna After Urogynecologic Surgery A Randomized Controlled Trial","Inclusion Criteria:\n\n* Inclusion criteria includes women scheduled for urogynecologic surgery for pelvic organ prolapse and\u002For stress urinary incontinence and at least 18 years old.\n\nExclusion Criteria:\n\n* Exclusion criteria include undergoing concomitant bowel surgery (colonic resection, anal sphincter repair, rectovaginal fistula repair, rectopexy) or placement of a sacral neuromodulation device alone.",true,"FEMALE","18 Years",{"count":20,"type":21},254,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The goal of this study is to evaluate whether polyethylene glycol 3350 (PEG3350) versus senna is better at relieving postoperative constipation after urogynecologic surgery. The main questions it aims to answer are:\n\nWhat number of patients taking PEG3350 have obstructed defecation syndrome (ODS), a form of constipation, vs those taking senna in the week after urogynecologic surgery? What patient-level and procedure-level characteristics are associated with postoperative ODS, in patients taking PEG3350 vs senna? participants will: Take their randomized medication daily for seven days after surgery Fill out an ODS questionnaire before and one week after surgery Complete a daily bowel diary for 7 days after surgery",[27,28],"Obstructive Defecation Syndrome","Postoperative Constipation",[30,31],"obstructive defecation syndrome (ODS)","Postoperative constipation","RECRUITING","2025-05-21",{"date":35,"type":36},"2025-05-28","ACTUAL",{"date":38,"type":36},"2025-04-23",{"date":40,"type":21},"2027-07",{"name":42,"class":43},"St. Joseph's Health, New York","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":4},"100562556","fat-injection-for-rectocele-treatment-a-novel-approach-100562556","NCT06604702","Fat Injection for Rectocele Treatment: A Novel Approach","Fat Injection for Treatment of Rectocele a Novel Technique for Treatment of Tectocele","Inclusion Criteria:\n\n* Female patients aged between 18 and 60 years.\n* Diagnosis of rectocele confirmed by defecography, with a rectocele size of 2 cm (mild) to 4 cm (moderate).\n* Presenting with symptoms of obstructive defecation syndrome, including constipation, incomplete defecation, and\u002For vaginal bulge.\n* Able to provide written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Patients who have previously undergone surgical repair of rectocele.\n* Presence of thrombosed hemorrhoids.\n* History of sclerotherapy injection for rectocele.\n* Diagnosis of anal stenosis.\n* History of coagulopathy or current use of anticoagulant or antiplatelet medications.\n* Refusal or inability to provide informed consent.","60 Years",{"count":54,"type":21},25,[56],"NA","This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall. Women aged 18 to 60 years with mild to moderate rectocele, presenting with symptoms such as obstructive defecation or vaginal bulge, will undergo submucosal fat injections. The study will assess the procedure\\'s ability to alleviate symptoms and reduce prolapse recurrence. This prospective, single-arm trial will be conducted at Cairo University Hospitals.",[59,60,27],"Rectocele","Pelvic Organ Prolapse",[59,62,63,64,65,60,66],"Pelvic Floor Dysfunction","Fat Grafting","Autologous Fat Injection","Obstructive Defecation","Vaginal Bulge","NOT_YET_RECRUITING","2024-09-17",{"date":70,"type":36},"2024-09-19",{"date":72,"type":21},"2024-10-20",{"date":74,"type":21},"2025-10-20",{"name":76,"class":43},"Cairo University"]