[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"occupational-exposure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:occupational-exposure":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,45,71,99,134,159],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100643029","gansu-nurses-health-cohort-study-100643029",false,"NCT07645911","Gansu Nurses' Health Cohort Study","Gansu Nurses' Health Surveillance and Improvement Action Program","Inclusion Criteria:\n\n1. Age ≥ 18 years;\n2. Able to communicate freely, have the ability to act, and agree to participate in this study.\n\nExclusion Criteria:\n\n1. Resigned from the hospital;\n2. Without a nursing license;\n3. Have a history of mental illness or severe cognitive impairment.",true,"ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","This study aims to understand the health status, work stress, and occupational exposure in the work environment among nurses in Gansu Province, China. We will collect information through questionnaires and conduct follow-up surveys every two years. The results of this study will help improve working conditions for nurses in the future and provide scientific evidence for developing health protection policies for the nursing workforce.",[25,26,27,28,29],"Nurses' Occupational Health","Mental Health","Chronic Diseases","Occupational Exposure","Reproductive Health",[31,32,33],"Nurses, Occupational Health, Questionnaire Survey","Nurse health status","Nurse Health Cohort Study","NOT_YET_RECRUITING","2026-06-10",{"date":37,"type":38},"2026-06-12","ACTUAL",{"date":35,"type":21},{"date":41,"type":21},"2032-12-31",{"name":43,"class":44},"LanZhou University","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100640455","clinical-utility-of-libs-multi-element-imaging-and-the-iff-algorithm-in-chronic-lung-diseases-100640455","NCT07597187","Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases","Evaluation of the Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm for the Etiological and Medico-Legal Management of Chronic Lung Diseases","PNEUMO-LIBS","Inclusion Criteria:\n\n* Adult patient aged 18 years or older.\n* Diagnosis or documented clinical suspicion of chronic lung disease, including interstitial lung disease, pulmonary granulomatosis such as sarcoidosis, or pulmonary emphysema.\n* Availability of a lung tissue biopsy sample obtained during routine medical care and stored as a formalin-fixed paraffin-embedded sample.\n* Sufficient medical record information to document the clinical context, occupational or environmental exposure history, smoking status, imaging, pathology reports, and other relevant routine-care data.\n* No documented objection to the secondary use of health data and biological samples for this research.\n\nExclusion Criteria:\n\n* Documented objection to participation in the study or to the secondary use of health data or biological samples for research.\n* Missing, unavailable, degraded, or technically unusable biopsy sample.\n* Insufficient medical record information to document the clinical context or exposure history.\n* Lung condition outside the scope of the study, such as isolated acute infection, isolated cardiac disease, or primary lung cancer.\n* Patient under legal protection when the applicable legal conditions for non-opposition cannot be fulfilled.",{"count":54,"type":21},70,"PNEUMO-LIBS is a multicenter, non-interventional observational study designed to evaluate whether multi-element tissue imaging by Laser-Induced Breakdown Spectroscopy (LIBS), combined with an artificial intelligence-based analysis tool called Interesting Features Finder (IFF), may help physicians better understand the possible causes of chronic lung diseases.\n\nThe study focuses on adult patients with chronic lung diseases for which a lung biopsy has already been performed as part of routine medical care. These diseases include diffuse interstitial lung diseases, pulmonary granulomatoses such as sarcoidosis, and emphysema, especially when an environmental or occupational exposure is suspected but not clearly demonstrated.\n\nSome chronic lung diseases may be influenced by inhaled mineral or metallic particles, such as silica, aluminum, titanium, or other metals. However, these exposures are often difficult to document at the individual patient level. Standard clinical, radiological, and pathological investigations do not usually provide direct information on the presence and distribution of such elements within lung tissue.\n\nLIBS is an imaging technique that can detect and map chemical elements directly in tissue samples, including archived formalin-fixed paraffin-embedded biopsy blocks. In this study, lung biopsy samples will be analyzed with LIBS to search for elemental signatures that may be compatible with occupational or environmental exposures. The IFF algorithm will then be used to help interpret the LIBS data and identify rare or unexpected elemental signals.\n\nThe study does not require any additional biopsy, blood test, imaging examination, treatment, or hospital visit for participants. It uses tissue samples and medical data already collected during routine care. The results of LIBS and IFF analyses will be presented to the treating physician or investigator, who will complete standardized online questionnaires at three time points: before receiving the LIBS results, after receiving the LIBS report, and after receiving the IFF-assisted interpretation.\n\nThe main objective is to assess the perceived clinical utility of LIBS imaging for physicians, particularly regarding etiological understanding, possible occupational disease recognition, and prevention-oriented reasoning. Secondary objectives include assessing the added value of the IFF algorithm and evaluating the feasibility of a centralized multicenter workflow for sample transfer, LIBS analysis, IFF processing, result reporting, and questionnaire completion.\n\nThe study aims to include approximately 70 patients across several French hospital centers. Its results may support the development of future diagnostic, occupational health, and environmental medicine approaches, without modifying the medical care of participants during the study.",[57,58,59,60,61,28],"Interstitial Lung Diseases (ILD)","Pulmonary Emphysema","Chronic Lung Diseases","Occupational Lung Diseases","Environmental Exposure","2026-05-12",{"date":64,"type":38},"2026-05-19",{"date":66,"type":21},"2026-07-01",{"date":68,"type":21},"2027-07-01",{"name":70,"class":44},"University Hospital, Grenoble",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":4},"100636221","ai-supported-gamified-training-for-sharps-injury-prevention-in-nurses-100636221","NCT07562867","AI-Supported Gamified Training for Sharps Injury Prevention in Nurses","The Effect of An Artifıcial Intelligence-Supported Gamifıed Training Program on Nurses' Knowledge and Attitudes Toward The Prevention of Sharps Injuries","Inclusion Criteria:\n\n* Registered nurses working in the participating hospitals\n* Working in the institution for at least 2 months (Phase 1) or newly employed within the last 1 month (Phase 2)\n* Willing to participate in the study\n* Able to use smartphone-based technologies\n* Providing written informed consent\n\nExclusion Criteria:\n\n* Having received prior training based on the Health Belief Model for sharps injury prevention\n* Previous professional nursing experience before current employment (for newly recruited nurses in Phase 2)\n* Being on leave during the data collection period\n* Failure to attend training sessions (intervention group)\n* Incomplete data collection forms\n* Withdrawal from the study at any stage",{"count":79,"type":21},36,"INTERVENTIONAL",[82],"NA","This study aims to evaluate the effect of a Health Belief Model (HBM)-based, artificial intelligence (AI)-supported gamified training program on nurses' knowledge and attitudes toward the prevention of sharps injuries. Sharps injuries remain a significant occupational risk for healthcare workers, particularly nurses, despite existing standard precautions.\n\nThe study will be conducted in two phases. In the first phase, the validity and reliability of the Sharps Injury Prediction Scale will be tested in a nurse population. In the second phase, a quasi-experimental pretest-posttest control group design will be used to assess the effectiveness of the intervention.\n\nThe study will be carried out in two hospitals from the same healthcare group located in different cities to prevent interaction between groups. A total of 36 nurses will be included, with 18 participants in the intervention group and 18 in the control group.\n\nThe intervention group will receive a structured, HBM-based training program consisting of seven sessions incorporating AI-supported content, gamified scenarios, interactive materials, and feedback mechanisms to enhance engagement and promote behavior change. The control group will receive routine institutional training on sharps injury prevention.\n\nData will be collected at baseline, immediately after the intervention, and two months later. Outcome measures include nurses' knowledge, attitudes toward safe sharps use, and sharps injury risk perception.\n\nIt is expected that the AI-supported gamified training program will significantly improve knowledge, attitudes, and risk awareness compared to routine training. The findings may support the integration of innovative, theory-based educational interventions into institutional training programs to enhance occupational safety.",[85,86,28],"Sharps Injuries","Needlestick Injuries",[88,89],"Sharps injuries","Nursing education","2026-04-26",{"date":92,"type":38},"2026-05-01",{"date":94,"type":21},"2026-06-01",{"date":96,"type":21},"2027-06-01",{"name":98,"class":44},"Baskent University",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":80,"phases":108,"briefSummary":109,"conditions":110,"keywords":113,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":133},"100635568","a-multilevel-intervention-to-prevent-noise-exposure-in-farmworkers-100635568","NCT07554378","A Multilevel Intervention to Prevent Noise Exposure in Farmworkers","POP","Inclusion Criteria:\n\n* Age 18 years or older\n* Currently employed as a farmworker or supervisor at a participating farm\n* Able to provide informed consent\n* Able to understand and communicate in Spanish or English\n\nExclusion Criteria:\n\n* Not currently working at a participating farm at the time of recruitment\n* Unable or unwilling to wear a personal noise dosimeter during a work shift\n* Unable to complete study procedures (e.g., surveys or training)",{"count":107,"type":21},200,[82],"This study will test a program to reduce noise exposure and prevent hearing loss among farmworkers. Farmworkers are often exposed to high levels of noise from machinery, which can lead to hearing loss over time.\n\nFarms will be randomly assigned to either receive the program or serve as a comparison group. The program includes a short educational video, group discussion, and hands-on training on how to use hearing protection (such as earplugs). Supervisors will also receive brief training on how to support hearing protection use in the workplace.\n\nParticipants will wear a small device (dosimeter) during a work shift to measure noise exposure before the program and again about one month later. Participants will also complete surveys about their knowledge, attitudes, and behaviors related to hearing protection.\n\nA subset of participants will be invited to take part in interviews to understand barriers and facilitators to using hearing protection and implementing the program.\n\nThe results of this study will help inform future efforts to improve hearing health and reduce noise exposure in agricultural settings.",[111,112,28],"Noise Exposure","Hearing Loss, Noise-Induced",[114,115,116,117,118,119,120,121,122,123],"farmworkers","agriculture","hearing protection","earplugs","occupational noise","hearing conservation","implementation science","Community Health Workers","Workplace intervention","Cluster randomized trial","2026-04-21",{"date":126,"type":38},"2026-04-28",{"date":128,"type":21},"2026-10",{"date":130,"type":21},"2032-07",{"name":132,"class":44},"San Diego State University",1,{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":16,"sex":141,"minAge":142,"maxAge":143,"enrollmentInfo":144,"targetDuration":4,"studyType":80,"phases":146,"briefSummary":147,"conditions":148,"keywords":4,"overallStatus":149,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":133},"100601916","unloading-maneuvers-during-spinal-flexion-exposure-100601916","NCT07116720","Unloading Maneuvers During Spinal Flexion Exposure","The Effect of Unloading Maneuvers During Spinal Flexion Exposure","Inclusion Criteria:\n\n* Occupational workers with a predominantly non static job (e.g. combination of sitting and standing)\n\nExclusion Criteria:\n\n* History of chronic low back pain\n* Episode of acute low back pain\n* Hip injury in the past six months\n* Previous spine, pelvis or hip surgery\n* Hypermobility, diagnosed with the Beighton score\n* High intensity resistance training (\\> 75 % of 1 repetition maximum) more than two times a week\n* Sporting or recreational activities, that include repetitive spinal flexion or maintenance of a flexed posture (for example cycling or rowing).","MALE","30 Years","55 Years",{"count":145,"type":21},30,[82],"An experimental study, which will aim to investigate the acute effects of unloading maneuvers during an intermittent spinal flexion protocol on changes in trunk mechanical and neuromuscular properties.",[28],"RECRUITING","2025-08-06",{"date":152,"type":38},"2025-08-12",{"date":154,"type":21},"2025-08-25",{"date":156,"type":21},"2025-10-15",{"name":158,"class":44},"University of Primorska",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":143,"enrollmentInfo":165,"targetDuration":4,"studyType":80,"phases":167,"briefSummary":168,"conditions":169,"keywords":176,"overallStatus":149,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":133},"100572158","non-invasive-system-to-deliver-therapeutic-hypothermia-for-protection-against-noise-induced-hearing-loss-100572158","NCT06729632","Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss","Inclusion Criteria:\n\n* Adults aged 18-55 years old at the time of signing the consent form\n* Fluency in English\n\nExclusion Criteria:\n\n* Abnormal tympanometric findings\n* Abnormal pure tone audiometry from 500-8,000 Hz (Non-firefighters only)\n* Significant history of noise exposure (Non-firefighters only)\n* Temporomandibular joint disorder\n* Otologic pathologies (including, but not limited to): acoustic neuroma\u002Fvestibular schwannoma, chronic ear disease, Meniere's disease, documented fluctuating hearing loss, or ototoxicity\n* Current recipients of medical, pharmacologic, or therapeutic intervention for tinnitus or other otologic conditions\n* Active hearing aid users\n* Adults unable to consent",{"count":166,"type":21},116,[82],"The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia devices for preservation of sensory structures in the cochlea after noise exposure. The main aims of the study are:\n\n1. To test the safety and best duration for use for a new hypothermia device.\n2. To determine if the hypothermia device helps decrease noise-induced hearing loss in a group of firefighters.\n\nParticipants will wear the mild therapeutic hypothermia therapy devices immediately after a fire service shift serially over a year. Researchers will compare results from those receiving the therapy to those from a control group (individuals receiving no therapy and a sham therapy).",[111,170,171,172,173,28,174,175],"Noise-induced Hearing Loss","Noise; Adverse Effect","Mild Therapeutic Hypothermia","Cooling","Occupational Health","Hidden Hearing Loss",[177,178,179,180,181,182,183,184],"hearing preservation","hearing loss","noise-induced hearing loss","noise exposure","mild therapeutic hypothermia","cooling","post-exposure","prevention","2025-03-28",{"date":187,"type":38},"2025-04-02",{"date":189,"type":38},"2024-12-19",{"date":191,"type":21},"2026-12-31",{"name":193,"class":194},"Restorear Devices LLC","INDUSTRY"]