[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"off-pump-coronary-artery-bypass-graft\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:off-pump-coronary-artery-bypass-graft":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100605541","postural-mobilization-compared-to-noradrenaline-only-in-off-pump-cabg-surgery-100605541",false,"NCT07163858","Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery","Comparison of Hemodynamic Management by Postural Mobilization Versus Chemical Vasoconstriction Using Noradrenaline Exclusively in Off-pump Coronary Artery Bypass Graft Surgery: A Prospective, Randomized, Comparative, Single-center Study.","OPTICAB","Inclusion Criteria:\n\n* Adult patient\n* patient requiring isolated coronary bypass surgery\n* Elective procedure or medical emergency\n* First cardiac surgery\n* Patient with an EF ≥30%\n* Mandatory affiliation to a social security system\n* Signed informed consent form\n* Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure\n\nExclusion Criteria:\n\n* Contraindication to an inotropic substance (only NA will be used)\n* Contraindication to passive leg raising\n* Patient in a life-threatening emergency\n* History of cardiac surgery\n* Bilateral iliac or common femoral artery occlusion\n* EF \\\u003C 30%\n* Pregnancy and breastfeeding\n* Renal failure (GFR \\\u003C 40 ml\u002Fmin\u002F1.73 m²)\n* Patient with bilateral thigh amputation\n* Class III obesity BMI \\> 40 kg\u002Fm²","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+\u002F- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.",[27,28,29,30,31,32,33,34],"Coronary Artery Disease With Need for Bypass Surgery","Coronary Artery Disease(CAD)","Coronary Artery Bypass","Off Pump Coronary Artery Bypass Graft","Off Pump Coronary Artery Bypass Surgery","Hemodynamic Management","Hemodynamic Optimization","Noradrenaline",[36,37,38,39],"open-heart coronary bypass","passive leg raising","hemodynamic management","off-pump CABG surgery","RECRUITING","2025-11-25",{"date":43,"type":44},"2025-12-03","ACTUAL",{"date":46,"type":44},"2025-10-06",{"date":48,"type":21},"2027-08",{"name":50,"class":51},"Infirmerie Protestante de Lyon","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":73,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":52},"100593147","clinical-impact-of-surgical-wound-morbidity-according-to-the-type-of-saphenous-vein-harvesting-technique-endoscopic-vs-open-in-patients-undergoing-myocardial-revascularization-surgery-100593147","NCT07002658","Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery","Endoscopic Saphenous Vein Harvesting Versus Conventional Open Harvesting in Patients Undergoing Coronary Artery Bypass Grafting, Either Alone or in Combination With Another Cardiac Surgical Procedure, in Terms of the Clinical Impact of Surgical Wound Morbidity","EndOSiC","Inclusion Criteria:\n\n* Patients undergoing coronary artery bypass grafting (CABG), alone or in combination with other surgery (valve or arrhythmia surgery), with or without cardiopulmonary bypass (CPB), in which preoperative evaluation includes the plan to use a short saphenous vein segment (alone or in addition to arterial conduits).\n* Availability of a surgeon or cardiac surgery resident trained in endoscopic harvesting in the operating room.\n* Patients undergoing myocardial revascularization surgeries with or without extracorporeal circulation.\n* Patients undergoing concomitant cardiac valve replacement surgery, atrial fibrillation surgery, and others, in addition to CABG\n\nExclusion Criteria:\n\n* Emergent surgery or procedures performed during cardiorespiratory arrest\n* Myocardial revascularization with arterial grafts only\n* Presence of varicose veins\n* History of infrainguinal vascular surgery\n* Presence of ulcers and\u002For active infection in the lower limbs\n* Previous stroke with neurological sequelae in the legs\n* History of deep vein thrombosis in the legs\n* Pregnancy\n* Age under 18 years\n* Lack of signed informed consent",{"count":62,"type":21},356,[24],"The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in combination with another cardiac surgical procedure (valve surgery or arrhythmia surgery). The main questions the trial aims to answer are:\n\nDoes the endoscopic technique reduce surgical wound morbidity in terms of shorter hospital stays? Does endoscopic saphenous harvesting reduce the use of antibiotics for saphenectomy wound infections? Does the endoscopic technique reduce need for wound dressings due to necrosis and\u002For wound infection, and reduce need for analgesic treatment for wound pain? This prospective, randomized study will be conducted in the Cardiovascular Surgery Service at Hospital Clínico San Carlos.\n\nParticipants will be randomly assigned to a different saphenectomy technique. All patients will be assessed for saphenectomy wound complications upon discharge, and by phone call at 7 days, 1 month, and 3 months following the intervention.",[66,67,68,69,70,71,30,72],"CABG-patients","Saphenectomy","Endoscopic Surgery","Wound Complications","Antibiotic Use","Cardiac Surgery","Coronary Artery Bypass Graft With or Without ECC",[74,75,76,77],"endoscopic vein harvesting","CABG surgery","open vein harvesting","wound morbidity","NOT_YET_RECRUITING","2025-06-03",{"date":81,"type":44},"2025-06-06",{"date":83,"type":21},"2025-07-01",{"date":85,"type":21},"2026-08-01",{"name":87,"class":51},"Hospital San Carlos, Madrid"]