[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"old-age-debility\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:old-age-debility":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,47,74,98,120,154,184,209,240],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100642102","combined-effects-of-nmes-and-lirt-on-muscle-strength-girth-and-physical-endurance-in-the-geriatric-population-100642102",false,"NCT07646405","Combined Effects of NMES and LIRT on Muscle Strength, Girth, and Physical Endurance in the Geriatric Population","Combined Effects of Neuromuscular Electrical Stimulation and Low-intensity Resistance Training on Muscle Strength, Girth, and Physical Endurance in Geriatric Population","Inclusion Criteria:• Age: 65 to 85 (35)\n\n* Both male and female will be added(29)\n* Patients with low calf muscle mass \\\u003C31.5 cm for females and \\\u003C33.5 cm for males will be included in this study(36).\n* Participants able to complete the Five Times Sit-to-Stand Test in ≤ 10 seconds (men) or ≤ 11 seconds (women)(37).\n* Participants must have ability to walk independently and absence of severe medical conditions(29).\n* Participants who takes \\> 12 seconds to complete TUG will be included in this study(38\n\nExclusion Criteria:• Participants with contraindications to NMES or RT, such as pacemakers or severe cardiovascular disease(29).\n\n* Participants with a MoCA score of less than 26 will be excluded to ensure adequate cognitive ability to comprehend and follow the study protocol, including exercise and neuromuscular stimulation procedures (39).\n* Participants with any musculoskeletal issues will be excluded from this study(35).\n* Participants with neuromuscular disorders that may affect muscle strength or function(29).","ALL","65 Years","85 Years",{"count":20,"type":21},44,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will employ a randomized controlled trial design with a pre-post design to investigate the combined effects of Neuromuscular Electrical Stimulation (NMES) and Low-Intensity Resistance Training (LIRT) on muscle strength, muscle girth, and physical endurance in the geriatric population. Participants will be randomly assigned to either an intervention group or a control group.",[27],"Old Age; Debility",[29,30,31,32,33],"NMES","LIRT","Muscle strength","Girth","Geriatic population","RECRUITING","2026-06-08",{"date":37,"type":38},"2026-06-12","ACTUAL",{"date":40,"type":38},"2026-05-17",{"date":42,"type":21},"2026-08-06",{"name":44,"class":45},"Riphah International University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":46},"100580864","impact-of-a-physical-exercise-program-in-a-rural-area-100580864","NCT06842849","Impact of a Physical Exercise Program in a Rural Area","Impact of a Physical Exercise Program on the Physical, Podiatric and Mental Health of the Adult Population in a Rural Area","Inclusion Criteria:\n\n* Adults over 59 years of age.\n* Patients who comply with accelerometer times for 7 days.\n* Patients who correctly complete the accelerometer registration sheet.\n* Patients who complete the informed consent\n\nExclusion Criteria:\n\n* Patients who do not wear the accelerometer 600 minutes a day for at least 3 days on weekdays and 480 minutes for at least 1 day on the weekend.\n* Patients who suffer from illness during data collection.\n* Patients who do not wear the accelerometer for 7 days. Be in IPAQ category 1 (low level of AF).",true,"59 Years",{"count":57,"type":21},140,[24],"With this work we want to assess whether there are differences in the amount of physical activity per week, measured by accelerometry in 3 groups of subjects, where one group (G1) has been carrying out a PA program called \"Enguera Sé Saludable\" for a year. another group (G2) newly introduced to the same exercise program, and a control group (G3) that does not carry out an exercise program but declared itself active.",[27],[62,63,64],"old adults","exercise","accelerometry","2026-04-27",{"date":67,"type":38},"2026-04-28",{"date":69,"type":38},"2025-10-22",{"date":71,"type":21},"2026-12-31",{"name":73,"class":45},"University of Valencia",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":93,"leadSponsor":95,"locationsCount":46},"100630433","relationship-between-neuropathic-pain-and-geriatric-assessment-parameters-in-patients-aged-80-years-and-older-100630433","NCT07487610","Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older","Evaluation of the Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older","Inclusion Criteria:\n\n* Age 80 years or older\n* Full cooperation\n* Complete comprehensive geriatric assessment parameters\n\nExclusion Criteria:\n\n* Patients with dementia classified as CDR-2 or CDR-3 according to the Clinical Dementia Rating (CDR) Scale\n* Patients who have experienced an acute illness within the last 1 month (e.g., infection, fracture, or cerebrovascular disease)\n* Patients with a psychotic disorder\n* Patients with severe hearing loss\n* Patients with a history of malignancy","80 Years",{"count":83,"type":21},450,"OBSERVATIONAL","This study aimed to determine the frequency of neuropathic pain in individuals aged 80 years and older and to evaluate the relationship between neuropathic pain and comprehensive geriatric assessment parameters.",[87,27,88],"Neuropathic Pain","Pain","2026-03-17",{"date":91,"type":38},"2026-03-23",{"date":89,"type":38},{"date":94,"type":21},"2026-06-30",{"name":96,"class":97},"Sultan 1. Murat State Hospital","OTHER_GOV",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":110,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":46},"100614963","efficacy-of-subclavian-veinartery-diameter-index-in-predicting-the-incidence-of-the-spinal-induced-hypotension-in-geriatric-patients-100614963","NCT07286422","Efficacy of Subclavian Vein\u002FArtery Diameter Index in Predicting the Incidence of the Spinal-Induced Hypotension in Geriatric Patients","Efficacy of Subclavian Vein\u002FArtery Diameter Index in Predicting the Incidence of the Spinal-Induced Hypotension in Geriatric Patients: A Prospective, Observational Study.","Inclusion Criteria:\n\n* 1\\. Patients aged 65 or older. 2. Lower body surgeries to be done with spinal anesthesia. 3. BMI less than 30 kg\u002Fm2. 4. Patients with ASA I-III.\n\nExclusion Criteria:\n\n\\- 1. Patient refusal. 2. Patients with a history of peripheral arterial disease or atherosclerosis 3. Patients with a body mass index of greater than 30 kg\u002Fm2 4. Major bloody surgeries (class C surgeries) 5. Patients with a history of cardiovascular disorders, including arrhythmias, heart failure, tricuspid or mitral regurgitation, dilated right atrium or ventricle, AF, ejection fraction \\\u003C 45%, uncontrolled hypertension, systolic blood pressure \\\u003C90 mmHg, dyspnea, agitation.\n\n6\\. Patients with increased intra-abdominal pressure, intra-abdominal mass compressing the IVC.",{"count":106,"type":21},107,"The hypothesis of the study will be that the subclavian vein\u002Fsubclavian artery diameter (SCVD\u002FSCAD) index will be a good predictor of spinal-induced hypotension in geriatric patients.",[109,27],"Spinal Induced Hypotension","NOT_YET_RECRUITING","2025-12-02",{"date":113,"type":38},"2025-12-16",{"date":115,"type":21},"2026-01",{"date":117,"type":21},"2026-07",{"name":119,"class":45},"Tanta University",{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":127,"enrollmentInfo":128,"targetDuration":4,"studyType":22,"phases":130,"briefSummary":131,"conditions":132,"keywords":138,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":46},"100417430","multicomponent-prehabilitation-and-outcomes-in-elderly-patients-with-frailty-100417430","NCT04715581","Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty","Effect of Multicomponent Prehabilitation on Early and Long-term Outcomes in Elderly Patients With Frailty After Digestive Surgery for Cancer: A Randomized-controlled Study","Inclusion criteria:\n\n1. Age ≥65 years but \\\u003C90 years;\n2. Scheduled to undergo major surgery for digestive cancer with an expected duration of 2 hours and longer, including cancers of esophagus, stomach, small intestine, colon, rectum, pancreas, liver, and biliary tract;\n3. Clinical Frailty Scale ≥5;\n4. Provide written informed consent.\n\nExclusion Criteria:\n\n1. Preoperative history of schizophrenia, epilepsy, Parkinsonism, or myasthenia gravis;\n2. Inability to communicate due to coma, profound dementia, or language barrier;\n3. Inability to participate in preoperative rehabilitation due to paralysis, fracture or other movement disorder;\n4. Inability to take oral diet due to preoperative gastrointestinal disease or other disease;\n5. Severe heart dysfunction (left ventricular ejection fraction \\\u003C30% or New York Heart Association classification IV), severe hepatic dysfunction (Child-Pugh class C), severe renal dysfunction (undergoing dialysis before surgery), or American Society of Anesthesiologists classification of grade 4 or higher;\n6. Other reasons that are considered unsuitable for study participation.","89 Years",{"count":129,"type":21},540,[24],"The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.",[27,133,134,135,136,137],"Digestive Cancer","Surgery","Preoperative Rehabilitation","Nutrition Therapy","Outcomes",[139,140,141,142,143,144],"older patients","frailty","digestive cancer","prehabilitation","nutrition therapy","outcomes","2025-07-29",{"date":147,"type":38},"2025-07-31",{"date":149,"type":38},"2021-11-25",{"date":151,"type":21},"2028-12",{"name":153,"class":45},"Peking University First Hospital",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":54,"sex":16,"minAge":161,"maxAge":4,"enrollmentInfo":162,"targetDuration":4,"studyType":22,"phases":164,"briefSummary":165,"conditions":166,"keywords":168,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":180,"leadSponsor":182,"locationsCount":46},"100434530","dual-task-perturbation-training-for-oawmci-100434530","NCT04938349","Dual Task Perturbation Training for OAwMCI","Neuromechanisms of Falls in Older Adults With MCI: Targeting Assessment and Training of Reactive Balance Control","Inclusion Criteria:\n\n* Age group: Older adults between the age group \\> 55 years old with MOCA less than 26 out of 30 will be classified as mild cognitive impairment and those above 26 out of 30 as cognitively intact older adults .\n* Absence of any acute or chronic neurological (Stroke, Parkinson's disease, Alzheimer's disease), cardiopulmonary, musculoskeletal, or systemic diagnosis.\n* No recent major surgery (\\\u003C 6 months) or hospitalization (\\\u003C 3 months)\n* Not on any sedative drugs\n* Can understand and communicate in English\n* Ability to walk more than 10 meters without an assistive device\n\nExclusion Criteria:\n\n* Participants will not proceed with the study if any of the following occurs at baseline measurement: 1) HR \\> 85% of age-predicted maximal heart rate (HRmax) (HRmax = 220 - age), 2) systolic blood pressure (SBP) \\> 165 mmHg and\u002For diastolic blood pressure (DBP) \\> 110 mmHg during resting), and\u002For 3) oxygen saturation (measured by pulse oximeter) during resting \\\u003C 90%.\n* History of bone fracture or significant other systemic disease or surgery in the last six months\n* Specific to MRI participants: Self-reported presence of a pacemaker, metal implants other than orthopedic implants, and\u002For Claustrophobia, cataract surgery (lens not compatible to the MRI confirmed by the MRI technician)\n* Weighs \\> 220 lbs (Harness weight threshold)","55 Years",{"count":163,"type":21},142,[24],"Studies have determined that compared to cognitively intact older adults (CIOA), older adults with mild cognitive impairment (OAwMCI) exhibit more pronounced balance and gait impairments which lead to an increased risk of falls and mobility decline. Such impairments are evident during dual-tasking (i.e., simultaneous performance of cognitive and motor task) and OAwMCI have demonstrated an increased cognitive-motor interference (deteriorated performance of either or both cognitive\u002Fmotor task). Furthermore, our preliminary laboratory findings indicate that compared to CIOA, OAwMCI in response to large-magnitude treadmill perturbations exhibits poor reactive responses (first line of defense against balance loss) and are unable to modulate their responses as the magnitude of perturbation increases. Despite that conventional exercise methods offer beneficial effects; they comprise of self-initiated task-specific exercises and may not focus on training reactive responses. Additionally, due to the presence of subtle balance and gait deficits, clinical measures used may not be sensitive enough to determine the risk of fall post-training. Furthermore, these training methods incorporate multiple sessions due to which adherence to exercise training is difficult with only a fraction of the older adults benefiting from it. Therefore, it is essential to incorporate a task-specific strategy that promotes factors associated with falling like balance control, muscular responses, coordination of limbs, and cognition through which OAwMCI may acquire maximum benefits to prevent a balance loss. One feasible method, which harnesses technology that can be used to deliver balance disturbances either while standing or walking in a consistent and controlled manner, is via a custom-based motorized treadmill. The scientific rigor from preliminary studies has reported a successful reduction of falls through a single session exposing CIOA to multiple treadmill-induced perturbations during gait and has shown significant improvement in reactive responses. For that reason, this stage 1 pilot study will examine the feasibility, applicability, and tolerability of a combined cognitive, and perturbation training on biomechanical determinants associated with falls and promote physical activity: kinematic variables, muscular responses, and cognitive function.",[167,27],"Mild Cognitive Impairment",[169,170,171,172,173,174],"Dual-task training","Mild cognitive impairment","Perturbation-based training","treadmill training","cognitive-motor training","perturbation","2024-11-25",{"date":177,"type":38},"2024-11-26",{"date":179,"type":38},"2021-09-14",{"date":181,"type":21},"2026-08-31",{"name":183,"class":45},"University of Illinois at Chicago",{"id":185,"slug":186,"hasResults":11,"nctId":187,"briefTitle":188,"officialTitle":189,"acronym":190,"eligibilityCriteria":191,"healthyVolunteers":11,"sex":192,"minAge":193,"maxAge":4,"enrollmentInfo":194,"targetDuration":4,"studyType":22,"phases":196,"briefSummary":197,"conditions":198,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":201,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":207,"locationsCount":46},"100564030","significant-activities-in-the-integrated-person-centered-care-model-100564030","NCT06623864","Significant Activities in the Integrated Person-centered Care Model","Significant Activities in the Implementation of the Integrated Person-centered Care Model: Intervention Protocol","IO\u002F20240924","Inclusion Criteria:\n\n* That the direct care worker has a degree as a nursing assistant, dependency care technician, geroculturist or certificate of professionalism.\n* The worker must speak and understand Spanish.\n* The residence must offer service during the day, in the morning or afternoon shift.\n* Workers must have been with the department for more than 4 months.\n\nExclusion Criteria:\n\n* Workers who work night shift only.\n* Workers on rotating shifts in all departments of the residence.\n* Workers absent at the time of the study due to temporary leave, vacations or other causes.","MALE","60 Years",{"count":195,"type":21},10,[24],"The increasing life expectancy and global aging population necessitate changes in long-term gerontological services based on Person-Centred Care approaches. This study aims to improve Person-Centred Care in geriatric centers through meaningful activities and the role of occupational therapists and direct care professionals in developing these activities. A descriptive cross-sectional quasi-experimental design was proposed, with 10 participants.",[199,27],"Old Age; Dementia","2024-09-30",{"date":202,"type":38},"2024-10-02",{"date":204,"type":38},"2024-09-24",{"date":206,"type":21},"2025-01-20",{"name":208,"class":45},"Universidad de Burgos",{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":215,"eligibilityCriteria":216,"healthyVolunteers":54,"sex":16,"minAge":193,"maxAge":4,"enrollmentInfo":217,"targetDuration":4,"studyType":22,"phases":219,"briefSummary":220,"conditions":221,"keywords":226,"overallStatus":110,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":4},"100558635","brain-gym-therapy-on-quality-of-sleep-among-elderly-people-100558635","NCT06553690","Brain Gym Therapy on Quality of Sleep Among Elderly People","Impact of Brain Gym Therapy on Quality of Sleep Among Elderly People Attending Health Care Facilities","BG\u002FE","Inclusion Criteria:\n\nElderly individuals aged 60 years and above. Attending healthcare facilities and able to participate in the study. Experiencing issues with sleep quality, as determined by a score of 5 or higher on the Pittsburgh Sleep Quality Index (PSQI).\n\nWilling and able to provide informed consent. Physically capable of performing gentle physical exercises as part of Brain Gym Therapy\n\nExclusion Criteria:\n\nSevere cognitive impairment or dementia that would impede understanding or participation in the intervention.\n\nCurrent participation in another sleep intervention study. Presence of severe medical conditions that contraindicate physical activity (e.g., severe cardiovascular disease, musculoskeletal disorders).\n\nUse of sleep medications that could confound the study results. Recent history (within the past 6 months) of major psychiatric disorders, including severe depression or anxiety.\n\nAny condition that, in the opinion of the investigators, would make participation unsafe or not in the best interest of the participant.",{"count":218,"type":21},120,[24],"This clinical trial aims to evaluate the impact of Brain Gym Therapy on the quality of sleep among elderly individuals attending healthcare facilities. The study will explore whether this non-pharmacological intervention can improve sleep quality, which is often compromised in the elderly population due to various health conditions and age-related changes. Participants will undergo Brain Gym Therapy sessions over a specified period, and their sleep quality will be assessed using validated sleep measurement tools. The findings may provide insights into alternative methods for enhancing sleep in older adults.",[222,223,224,27,225],"Sleep Disorder","Insomnia","Cognitive Function Abnormal","Brain Gym Therapy",[225,227,228,229,230],"Sleep Quality","Cognitive Exercise","Non-Pharmacological Intervention","Insomnia in Elderly","2024-08-11",{"date":233,"type":38},"2024-08-14",{"date":235,"type":21},"2024-08-15",{"date":237,"type":21},"2024-10-12",{"name":239,"class":45},"Cairo University",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":244,"acronym":4,"eligibilityCriteria":245,"healthyVolunteers":54,"sex":16,"minAge":17,"maxAge":246,"enrollmentInfo":247,"targetDuration":4,"studyType":22,"phases":249,"briefSummary":250,"conditions":251,"keywords":254,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":267},"100555863","the-effect-of-home-visit-supported-nursing-education-program-on-some-parameters-in-elderly-people-living-alone-at-home-100555863","NCT06517615","The Effect of Home Visit Supported Nursing Education Program on Some Parameters in Elderly People Living Alone at Home","Inclusion Criteria:\n\n* Being 65 years or older\n* receiving home care services\n* agreeing to participate in the study\n* be literate\n\nExclusion Criteria:\n\n* Individuals under the age of 65\n* be mentally retarded\n* not volunteering","95 Years",{"count":248,"type":21},48,[24],"It is aimed to develop healthy lifestyle behaviors of elderly people living alone at home, reduce their loneliness levels and increase their social support capacity.The research was planned as a quasi-experimental research. The research population consists of elderly people living alone at home who are registered to the Elderly and Home Care Unit of a Municipality of a province.",[27,252,253],"Loneliness","Healthy Lifestyle",[255,256,257],"elderly","home visit","nursing","2024-07-18",{"date":260,"type":38},"2024-07-24",{"date":262,"type":38},"2024-04-25",{"date":264,"type":21},"2024-12-29",{"name":266,"class":45},"Kastamonu University",2]