[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"old-age-dementia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:old-age-dementia":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,78,98,126],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100626425","blood-biomarkers-for-alzheimer-disease-and-neuro-injury-to-estimate-the-association-with-cognitivefunctional-decline-and-mortality-in-a-real-world-population-of-geriatric-hospitalized-patients-bad-ger-100626425",false,"NCT07435467","Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive\u002FFunctional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)","Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive\u002FFunctional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER): a Multicenter, Observational, 3-arms, Prospective Study","BAD-GER","GROUP 1: Patients hospitalized for acute neurological disorders\n\nInclusion criteria:\n\n* Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis\u002Fmeningitis\n\nExclusion criteria:\n\n* no informed consent\n\nGROUP 2: Patients hospitalized for non-neurological diseases with dementia\n\nInclusion criteria:\n\n* inpatients with diagnosis of major neurocognitive disorder according to DSM-5 criteria (2013)\n\nExclusion criteria:\n\n* Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis\u002Fmeningitis\n* no informed consent\n\nGROUP 3: Patients hospitalized for non-neurological diseases without dementia\n\nInclusion criteria:\n\n* inpatients with non-neurological diseases\n\nExclusion criteria:\n\n* inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis\u002Fmeningitis\n* diagnosis of dementia\n* no informed consent","ALL","65 Years",{"count":20,"type":21},400,"ESTIMATED","OBSERVATIONAL","The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the retrospective analysis of Alzheimer's Disease and neurodegeneration biomarkers in an already available discovery cohort of 700 previously hospitalized geriatric patients.",[25,26],"Alzheimer Disease","Old Age; Dementia",[28,29,30,31,32,33],"aging","geriatric","biomarkers","inflammation","neurodegeneration","mortality","RECRUITING","2026-02-24",{"date":37,"type":38},"2026-02-27","ACTUAL",{"date":40,"type":38},"2025-04-09",{"date":42,"type":21},"2026-06-30",{"name":44,"class":45},"Istituto Nazionale di Ricovero e Cura per Anziani","OTHER",3,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100549929","exploring-patterns-of-use-and-effects-of-adult-day-programs-to-improve-trajectories-of-continuing-care-100549929","NCT06440447","EXploring Patterns of Use and Effects of Adult Day Programs to Improve Trajectories of Continuing CarE","EXploring Patterns of Use and Effects of Adult Day Programs to Improve Trajectories of Continuing CarE (EXPEDITE)","EXPEDITE","Inclusion criteria:\n\n* Persons aged 65 years and over\n* Initial RAI-HC assessment completed\n* Attendance of an adult day program (for cohort 1)\n* Receipt of any community-based continuing care services, other than adult day program (cohort 2)\n\nExclusion criteria:\n\n\\- No receipt of any community-based continuing care service",{"count":56,"type":21},500000,"This study seeks to understand the impact of Canada's adult day program on attendees and non-attendees, especially those with dementia and other co-morbidities. A retrospective cohort study will be conducted, including older adults in the community who do or do not attend adult day programs in Alberta, British Columbia, and Manitoba, Canada. The objectives are to (1) compare patterns of day program use (including non-use) by Canadian province (Alberta, British Columbia, Manitoba), and time, (2) compare characteristics of older adults by day program use pattern (including non-use), province, and time, and (3) to examine whether those who are exposed to day programs, compared to a propensity-score matched comparison group of non-exposed older adults in the community, enter long-term care homes at later times (primary outcome), are less likely to have depressive symptoms, physical and cognitive change, and have lower use of primary, acute, and emergency care (secondary outcomes).",[59,60,26,61],"Adult Day Programs","Continuing Care","Family\u002Ffriend Caregivers",[63,64,65,66,67],"Adult day programs","Older adults","Program evaluation","Cohort studies","Health administrative data","NOT_YET_RECRUITING","2025-01-21",{"date":71,"type":38},"2025-01-24",{"date":73,"type":21},"2025-03-01",{"date":75,"type":21},"2027-06-30",{"name":77,"class":45},"York University",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":85,"targetDuration":87,"studyType":22,"phases":4,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":92,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":96,"locationsCount":97},"100554273","assessing-the-impact-of-day-programs-on-individuals-living-with-dementia-and-their-familyfriend-caregivers-100554273","NCT06496945","Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family\u002Ffriend Caregivers","Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family\u002Ffriend Caregivers (AIDA-DemCare)","Inclusion Criteria:\n\n* Older adults (65+ years) with a diagnosis of dementia, who live in the community, and either attend an adult day program (cohort 1), or receive continuing care in the community with an initial RAI-HC assessment completed (cohort 2)\n* Primary caregiver (i.e., most involved with and informed about the care) of an eligible older adult\n\nExclusion Criteria:\n\n* Older adults with or without dementia who do not receive any community-based continuing care service\n* Day program attendees or community care recipients who do not have a diagnosis of dementia or who are younger than 65 years\n* Secondary caregivers",{"count":86,"type":21},3000,"2 Years","This study seeks to understand the effects of adult day programs on older adults, especially those with dementia, and their caregivers. A prospective cohort study will be conducted in the Canadian provinces of Alberta, British Columbia, Manitoba, and Ontario. Participants will be (1) older adults with dementia who attend a day program, and their caregivers, and (2) older adults with dementia in the community who do not attend a day program, and their caregivers. The objectives are to (1) evaluate the effects of day programs on attendee and caregiver outcomes, and (2) compare day program use patterns, attendee and caregiver social identities, day program characteristics, and day program outcomes between the 4 provinces, and (3) to explore what attendee and caregiver social identities and day program characteristics are associated with study outcomes, and with day program attendance\u002Fnon-attendance.",[59,60,26,90],"Family\u002FFriend Caregivers",[63,64,65,66,67],{"date":71,"type":38},{"date":94,"type":38},"2024-11-01",{"date":75,"type":21},{"name":77,"class":45},4,{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":106,"minAge":107,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":125},"100564030","significant-activities-in-the-integrated-person-centered-care-model-100564030","NCT06623864","Significant Activities in the Integrated Person-centered Care Model","Significant Activities in the Implementation of the Integrated Person-centered Care Model: Intervention Protocol","IO\u002F20240924","Inclusion Criteria:\n\n* That the direct care worker has a degree as a nursing assistant, dependency care technician, geroculturist or certificate of professionalism.\n* The worker must speak and understand Spanish.\n* The residence must offer service during the day, in the morning or afternoon shift.\n* Workers must have been with the department for more than 4 months.\n\nExclusion Criteria:\n\n* Workers who work night shift only.\n* Workers on rotating shifts in all departments of the residence.\n* Workers absent at the time of the study due to temporary leave, vacations or other causes.","MALE","60 Years",{"count":109,"type":21},10,"INTERVENTIONAL",[112],"NA","The increasing life expectancy and global aging population necessitate changes in long-term gerontological services based on Person-Centred Care approaches. This study aims to improve Person-Centred Care in geriatric centers through meaningful activities and the role of occupational therapists and direct care professionals in developing these activities. A descriptive cross-sectional quasi-experimental design was proposed, with 10 participants.",[26,115],"Old Age; Debility","2024-09-30",{"date":118,"type":38},"2024-10-02",{"date":120,"type":38},"2024-09-24",{"date":122,"type":21},"2025-01-20",{"name":124,"class":45},"Universidad de Burgos",1,{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":134,"sex":17,"minAge":107,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":110,"phases":137,"briefSummary":138,"conditions":139,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":125},"100462078","validation-of-the-reminder-dementia-risk-reduction-program-100462078","NCT05296980","Validation of the REMINDER Dementia Risk Reduction Program","Validation of a Multidomain Neuropsychological Intervention for Individuals at Risk of Dementia: the REMINDER Program","REMINDER","Inclusion Criteria:\n\n* Age 60 or older\n* CAIDE dementia risk score \\>8\n* Cognitive function: absence of significant cognitive impairment as per the Addenbrooke's Cognitive Examination-REVISED\n* Free of physical disabilities that preclude participation in the study\n* Willing to complete all study-related activities for 12 weeks\n\nExclusion Criteria:\n\n* Mild cognitive impairment or dementia;\n* Presence of any neurological event in their medical history that could compromise actual cognition.\n* Presence of any severe psychiatric disorder (mild depressive and anxiety symptoms meet inclusion criteria).\n* Unability to travel to the site where the sessions will be delivered (if so randomization will be circumscribed between the experimental harm REMINDER online and the control group.\n* Illiteracy",true,"75 Years",{"count":20,"type":21},[112],"Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies. While some RCTs have been developed in cognitive training interventions, comparative studies of merged interventions (cognitive, social and behavioral stimulation) with adequate control groups are absent, diminishing the professionals' trust on the adoption of these interventions for supporting patients. As such, the present proposal will develop a validation trial testing a multicomponent neuropsychological intervention (REMINDER), based on personal development, cognitive compensatory aids, meaningful goals setting, and behavior change techniques. The investigators will analyze its short\u002Flong-term gains and AD conversion rates. By aiming to provide a good validation study for REMINDER, the investigators will examine neurobiological, neurocognitive and functional outcomes of this intervention in comparison with an active control group (psychoeducation) in order to foster an effective outcome assessment of an intervention for individuals at risk of AD.",[140,141,26],"Healthy Aging","Risk Reduction","2024-05-07",{"date":144,"type":38},"2024-05-08",{"date":146,"type":38},"2022-04-01",{"date":148,"type":21},"2026-10",{"name":150,"class":45},"University of Coimbra"]