[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"one-piece-implants-versus-two-piece-implants-during-the-osseointegration-phase\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:one-piece-implants-versus-two-piece-implants-during-the-osseointegration-phase":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100576840","comparative-evaluation-between-one-piece-and-two-piece-implants-supporting-mandibular-screw-retained-all-on-four-full-arch-prosthesis-on-peri-implant-bone-changes-100576840",false,"NCT06790524","Comparative Evaluation Between One-piece and Two-piece Implants Supporting Mandibular Screw-retained All-On-Four Full-arch Prosthesis on Peri-implant Bone Changes.","Evaluation of Peri-implant Bone Changes Around One-piece Implant and Two-piece Implants Supporting Mandibular Screw-retained All-On-Four Full Arch Prosthesis: a Randomized Controlled Clinical Trial","RCT","Inclusion Criteria:\n\n* Completely edentulous patients, who can sign an informed consent will be considered eligible for this trial.\n* Residual bone height should have sufficient volume and quality for implant placement with a minimum of 12-14 mm in height and 6 mm in width.\n* Patients who already have existing maxillary and mandibular complete dentures, and after examination of the mandibular dentures, technical problems concerning denture design and\u002For occlusion are found, or who are dissatisfied with the retention and stability of their technically satisfactory mandibular dentures.\n\nExclusion Criteria:\n\n* \\- Patients with conditions that may contraindicate implant placement (e.g., Immunosuppressed or immunocompromised patients, patients under treatment of intravenous amino bisphosphonates, patients undergoing radiotherapy to the head and neck region).\n* Inadequate mouth opening\n* Heavy smokers, more than 10 cigarettes\u002Fday\n* Patients with poor oral hygiene and motivation.\n* Pregnancy or nursing.\n* Drug abusers.\n* Psychiatric problems or unrealistic expectations.\n* Patients with infection and or inflammation in the area intended for implant placement.","ALL","18 Years","70 Years",{"count":21,"type":22},22,"ESTIMATED","INTERVENTIONAL",[25],"NA","Evaluating the bone changing after receiving one-piece implants supported full arch prosthesis compared to the conventional two-piece implants.",[28,29],"Marginal Bone Loss","One-piece Implants Versus Two-piece Implants During the Osseointegration Phase",[31],"one-piece implants , All-On-Four, Marginal bone loss","NOT_YET_RECRUITING","2025-03-06",{"date":35,"type":36},"2025-03-07","ACTUAL",{"date":38,"type":22},"2025-03",{"date":40,"type":22},"2025-10",{"name":42,"class":43},"Cairo University","OTHER"]