[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oocyte-retrieval\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oocyte-retrieval":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100634187","phase-4-preoperative-indomethacin-and-paracetamol-for-pain-management-during-oocyte-retrieval-in-ivf-patients-100634187",false,"NCT07536425","Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients","Evaluating the Efficacy of Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients A Randomized Controlled Study","Inclusion Criteria:\n\n* Women undergoing oocyte retrieval for IVF or ICSI\n* Age 18-45 years\n* ASA physical status classification I or II\n* Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to Indomethacin, any NSAID, or Paracetamol\n* History of gastrointestinal bleeding or peptic ulceration\n* Renal impairment (GFR \\\u003C 30 ml\u002Fmin\u002F1.73m² or Creatinine \\> 1.04 mg\u002FdL)\n* Hepatic impairment (ALT \\> 55 U\u002FL, AST \\> upper limit of normal, ALP \\> upper limit of normal, Total Bilirubin \\> 1.2 mg\u002FdL, or Albumin \\\u003C 3.5 g\u002FdL)\n* Participation in another clinical trial that may interfere with the outcomes of this study",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},177,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","This is a randomized controlled trial evaluating the efficacy of preoperative analgesic medications - Indomethacin (100 mg per rectum) and Paracetamol\u002FAcamol (1,000 mg intravenously) - for pain management during oocyte retrieval in women undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).",[28,29],"Pain","Oocyte Retrieval",[31,32,33,34,35,36],"Oocyte retrieval","IVF","ICSI","Pain management","Assisted reproductive technology","Numerical Rating Scale","NOT_YET_RECRUITING","2026-04-27",{"date":40,"type":41},"2026-05-04","ACTUAL",{"date":43,"type":22},"2026-04-13",{"date":45,"type":22},"2027-12-31",{"name":47,"class":48},"Western Galilee Hospital-Nahariya","OTHER_GOV",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":62,"conditions":63,"keywords":69,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100572471","the-use-of-virtual-reality-technology-during-oocyte-retrieval-for-in-vitro-fertilization-100572471","NCT06733701","The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization","The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization: a Randomized Controlled Pilot Study","Inclusion Criteria:\n\n\\- All adults undergoing their first oocyte retrieval\n\nExclusion Criteria:\n\n* severe visual impairment\n* contraindications to using VR technology according to manufacturer specifications including:\n* severe motion sickness\n* epilepsy\u002Fprevious seizure\n* claustrophobia\n* current migraine\n* heart disease\n* use of medical devices such as cardiac pacemaker or hearing aids","43 Years",{"count":59,"type":22},50,[61],"NA","Ultrasound-guided oocyte retrieval (OR) is a short, but oftentimes painful procedure, during which the follicles are punctured trans-vaginally to obtain oocytes for in vitro fertilization (IVF). Conscious sedation is the most commonly used method of pain relief, yet several studies have shown that more than half of women report moderate to high levels of pain and up to 7% of women report extreme or unacceptable levels of pain during OR. Adjuvant virtual reality (VR) therapy has been explored to reduce psychological stress during dental procedures, burn wound care, colonoscopy, as well as other minor procedures. Hence, the purpose of this study is to evaluate the use of VR technology during IVF treatment, particularly with respect to tolerability, patient satisfaction, and pain reduction during oocyte retrieval.",[29,64,65,66,67,68],"Adverse Events","Procedural Anxiety","Pain Intensity","Satisfaction","Medication Administration",[70,29,71,72],"Virtual Reality","In Vitro Fertilization","Randomized Control Trial","2024-12-13",{"date":75,"type":41},"2024-12-18",{"date":77,"type":22},"2025-01-15",{"date":79,"type":22},"2025-12-31",{"name":81,"class":82},"Mount Sinai Hospital, Canada","OTHER",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":92,"briefSummary":93,"conditions":94,"keywords":101,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":110,"leadSponsor":111,"locationsCount":4},"100565054","phase-4-protocol-with-progestin-primed-ovarian-stimulation-ppos-from-the-beginning-of-stimulation-versus-protocol-with-gnrh-antagonists-for-ovarian-stimulation-in-patients-undergoing-duostim-with-embryo-accumulation-for-pgt-a-100565054","NCT06637189","Protocol with Progestin-primed Ovarian Stimulation (PPOS) from the Beginning of Stimulation Versus Protocol with GnRH Antagonists for Ovarian Stimulation in Patients Undergoing DUOSTIM with Embryo Accumulation for PGT-A.","PPDUO","Inclusion Criteria:\n\n* Regular menstrual cycles between 21 and 35 days, inclusive.\n* Indication of IVF with PGT-A.\n* Both ovaries present.\n* Ability to participate and complete the study.\n* Give and sign the consent to participate in the study.\n\nExclusion Criteria:\n\n* Endometriosis grade III\u002FIV\n* Concurrent participation in another study",{"count":91,"type":22},144,[25],"The PPOS protocol (Progestin-primed Ovarian Stimulation) involves avoiding ovulation during ovarian stimulation with progesterone. It is a reliable and safe protocol that has been widely used in recent years for in vitro fertilization, as it reduces the number of injections needed during controlled ovarian stimulation and is more cost-effective for patients.\n\nThe aim of this study is to compare two methods of ovarian stimulation for in vitro fertilization: the PPOS protocol (Group A) and the conventional protocol with injected antagonists (Group B). The goal is to determine whether both methods are equally effective in obtaining euploid embryos in the context of double ovarian stimulation.",[95,96,97,29,98,99,100],"Stimulation in the Ovary","Embryo","Oocyte","Fertilization in Vitro","Blastocyst","PGT-A",[102,103,104,105,100],"duostim","ovarian stimulation","progesterone","GnRH antagonists","2024-10-10",{"date":108,"type":41},"2024-10-15",{"date":108,"type":22},{"date":79,"type":22},{"name":112,"class":82},"Ginefiv"]