[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"opioid-dependency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:opioid-dependency":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100609992","preoperative-opioid-tapering-before-spine-surgery-100609992",false,"NCT07221786","Preoperative Opioid Tapering Before Spine Surgery","A Pilot Study of the Feasibility of Preoperative Opioid Tapering Before Spine Surgery Using Cognitive Behavioral Therapy and Measuring Postoperative Outcomes","Inclusion:\n\n* at least 18 years old\n* scheduled for major spine surgery (i.e. at least 1 level of fusion) with hospital admission of at least one night\n* scheduled for spine surgery at least 4 weeks ahead of time\n* takes between 40 and 200 oral morphine equivalents daily\n\nExclusion:\n\n* inability to use a computer or tablet for telemedicine encounters\n* non-English-speaking\n* inability to complete assessments\n* positive screen on the Columbia Suicide Screening Assessment","ALL","18 Years",{"count":19,"type":20},45,"ESTIMATED","INTERVENTIONAL",[23],"NA","This is a pilot study in which patients taking opioids chronically who are scheduled for spine surgery at least 4 weeks in advance will be randomly assigned to one of two groups: opioid tapering with education alone or opioid tapering with education plus cognitive behavioral therapy (CBT). The primary objective is to determine the proportion of each group that is successful in achieving their opioid tapering goals by the time of surgery.",[26,27,28],"Opioid Consumption, Postoperative","Pain After Surgery","Opioid Dependency",[30,31,32,33,34,35,36,37,38],"spine surgery","pain management","opioids","opioid use","depression","anxiety","opioid dependence","opioid tapering","cognitive behavioral therapy","RECRUITING","2026-03-23",{"date":42,"type":43},"2026-03-24","ACTUAL",{"date":45,"type":43},"2025-12-01",{"date":47,"type":20},"2026-12",{"name":49,"class":50},"Thomas Jefferson University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":21,"phases":62,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100572467","treatment-education-for-perinatal-women-and-their-community-support-100572467","NCT06733649","Treatment Education for Perinatal Women and Their Community Support","Treatment Education for Pre- and Postpartum Women and Their Community Support","Inclusion Criteria:\n\n* perinatal women treated with agonist medication\n* interest in study participation\n* interest in community support:\n* interest in study participation\n\nExclusion Criteria:\n\n* perinatal women not treated with agonist medication\n* not interested in study participation\n* not interested in community support:\n* not interested in study participation","80 Years",{"count":61,"type":20},80,[23],"The study evaluates the feasibility and acceptability of a 50 minute treatment education session for perinatal women with opioid use disorder and a community support person. The education session provides correct information about opioid agonist medications and neonatal abstinence syndrome.",[28],[36,66,67],"perinatal women","social support","NOT_YET_RECRUITING","2026-01-09",{"date":71,"type":43},"2026-01-12",{"date":73,"type":20},"2026-07-06",{"date":75,"type":20},"2027-12-05",{"name":77,"class":50},"Johns Hopkins University"]