[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"optimized-treatment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:optimized-treatment":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100532577","prospective-validation-of-adaptive-radiotherapy-art-in-patients-with-head-and-neck-tumors-100532577",false,"NCT06214611","Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors","Adaptive Radiotherapy in the Treatment of Patients With a Histologically Confirmed Malignant Tumor in the Head and Neck Region: Prospective Validation of ART in Patients With HNT (Prospektive Validierung Der ART Bei Patientinnen Und Patienen Mit Kopf-Hals Tumoren,)","ART in HNT","Inclusion Criteria:\n\n1. ECOG 0-1\n2. Histopathology confirmation\n3. Compliance\n4. Tumor in the head and neck region\n5. Indication for radiotherapy\n\nExclusion Criteria:\n\n1\\. Pregnancy","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","Adaptive radiotherapy (ART) includes image-guided radiotherapy (IGRT) and also offers further possibilities for plan adaptation. A particularly high benefit can be expected for patients in whom the clinical target volume (CTV) can show a significant change in shape from fraction to fraction due to anatomical deviations. The shape and position constancy of the CTV during the course of the series is examined in this trial. Dosimetric disadvantages of this type have not been reported so far. The aim of this study is to identify patients who benefit from ART at an early stage and to select them for this method, and then to continue to offer ART to this patient group. If a relevant reduction in the minimum planning target volume (PTV) margins with ART compared to IGRT is demonstrated in this study, patients could be treated with ART.",[27,28,29,30,31,32],"Head and Neck Cancer","Adaptive Radiotherapy","Radiation","Optimized Treatment","Protection of Organs at Risk","Dysphagia Reduction",[27,28,34,35,36],"Protection of organs at risk","Optimized treatment","Dysphagia reduction","RECRUITING","2024-09-25",{"date":40,"type":41},"2024-09-27","ACTUAL",{"date":43,"type":41},"2023-11-15",{"date":45,"type":21},"2027-12-15",{"name":47,"class":48},"University Hospital, Essen","OTHER"]