[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oral-cancer--oral-squamous-cell-carcinoma-oral-cavity-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oral-cancer--oral-squamous-cell-carcinoma-oral-cavity-cancer":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100568535","enhancing-oral-cancer-awareness-100568535",false,"NCT06682494","Enhancing Oral Cancer Awareness","Comparative Study on Enhancing Oral Cancer Awareness: Classical Educational Materials vs. AI-Powered Chatbot","Inclusion Criteria:\n\n* Identify as African American as defined by the US Census\n* Participants must be able to read, speak, and write in English\n\nExclusion Criteria:\n\n* Individuals who cannot physically or mentally participate in the research project will be excluded\n* Adults unable to consent\n* Individuals who are not yet adults (infants, children, teenagers)\n* Prisoners",true,"ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","To evaluate the impact of AI-powered chatbot interactions versus traditional educational handouts on increasing participants' knowledge of oral cancer and its prevention",[27,28,29,30,31,32],"Oral Cancer","Chatbot","Patient Education","Prevention","Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer","Oropharyngeal Cancers",[34,35,36],"AI-powered Chatbox","Oral cancer prevention","Socio-economic barriers","RECRUITING","2026-05-07",{"date":40,"type":41},"2026-05-08","ACTUAL",{"date":43,"type":41},"2025-09-24",{"date":45,"type":21},"2027-10-31",{"name":47,"class":48},"Virginia Commonwealth University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":49},"100606849","proactive-risk-based-optimization--notifications-for-treatment--outcomes-in-head--neck-cancer-100606849","NCT07180901","Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer","Proactive Risk-based Optimization & Notifications for Treatment & Outcomes (PRONTO) in Head & Neck Cancer: A Strategy to Reduce Delays From Surgery to Post-Operative Adjuvant Therapy in Head and Neck Cancer","PRONTO-HN","Inclusion Criteria:\n\n* All adult patients (age 18 or older).\n* Pathologically confirmed oral cavity or laryngeal squamous cell carcinoma.\n* Diagnosed from July 2024 to September 2026.\n* With planned primary intention surgical resection.\n* With or without adjuvant therapy.\n* Treated at the Centre Hospitalier de l'Université de Montréal.\n\nExclusion Criteria:\n\n* Patients who do not end up receiving surgery.\n* S-PORT \\> 180 days",{"count":59,"type":21},85,[24],"Delays between surgery and the initiation of post-operative radiotherapy (S-PORT) in head and neck cancer (HNC) patients are prevalent and associated with worse oncologic outcomes. This pilot study evaluates whether a proactive, automated care coordination system (PRONTO-HN) can improve adherence to recommended S-PORT intervals of ≤42 days at the Centre hospitalier de l'Université de Montréal (CHUM).\n\nThe study is a single-center, quasi-experimental, interrupted time-series design with two phases. Group A (control) includes patients treated before the intervention (using a prospectively maintained database from August 2024 to August 2025). Group B (intervention) includes patients treated with the new coordination system from September 2025 to September 2026.\n\nThe intervention includes automated alerts, multidisciplinary task coordination, and risk stratification based on a predictive model developed and published by our team. This model uses only pre-operative data to estimate the likelihood that a patient will require adjuvant therapy after surgery, stratifying patients into high- and low-risk categories. High-risk patients receive intensified coordination protocols, including early oncology and dental consultations and shorter target times for pathology results.\n\nPrimary objective: Reduce the proportion of patients with S-PORT \\> 42 days. Secondary\u002Ftertiary objectives: Reduce mean S-PORT time. Evaluate impacts on overall, locoregional, and disease-free survival in a 2- and 3-year follow up study.\n\nPatients are identified at the time the operating room request is submitted. Demographic, clinical, and oncologic data are collected and stored securely in REDCap. As the intervention is administrative in nature and does not modify patient care, consent is waived.\n\nStatistical analysis will evaluate the intervention's effect and identify predictors of delays. A sample of 38 patients per group provides adequate power to detect a drop in S-PORT \\> 42 days from 80% to 50%.",[31,63,64],"Head &Amp;Amp; Neck Squamous Cell Carcinoma","Larynx Squamous Cell Carcinoma",[66,67,68],"Surgery to post-operative radiation therapy interval","Treatment delays","Oral cavity cancer","2025-09-11",{"date":71,"type":41},"2025-09-18",{"date":73,"type":41},"2025-08-21",{"date":75,"type":21},"2029-10-21",{"name":77,"class":48},"Centre hospitalier de l'Université de Montréal (CHUM)"]