[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oral-halitosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oral-halitosis":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100605723","the-effect-of-regular-home-use-of-dual-light-antibacterial-photodynamic-therapy-apdt-or-the-use-of-a-powered-toothbrush-in-older-individuals-with-periodontitis-and-mild-cognitive-impairment-100605723",false,"NCT07166224","The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.","The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment: a Randomized Controlled Trial.","e-DENT II","Inclusion Criteria:\n\n* Adults aged ≥60 years\n* ≥15 teeth\n* Diagnosed periodontitis stage I-III\n* MMSE score between 22-28\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Antibiotic use (within 3 months)\n* Lumoral use within 3 months\n* Bisphosphonate medication\n* Immunosuppressive drugs or radiation therapy","ALL","60 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","Objective:\n\nTo compare three different oral hygiene regimens regarding plaque index (PI), bleeding on probing (BOP), the number of deepened periodontal pockets ≥4 mm (PPD), oral halitosis, and changes in oral health-related quality of life (OHRQoL) in an older population with periodontitis stage I-III and mild cognitive impairment.\n\n1. Are there improvements in plaque index (PI), number of bleeding on probing (BOP) sites, number of probing depths (PPD), and intraoral halitosis in the two test groups compared to the control group?\n2. Do the study interventions affect oral health-related quality of life in older adults with periodontitis and mild cognitive impairment?\n\nStudy design:\n\nType: Randomized controlled trial Duration: 6 months per participant, 2 years in total for data collection Participants: 90 participants divided into Intervention and Control groups\n\nIntervention Group A (Lumoral Dual-Light aPDT + Manual Toothbrush) Standardized oral hygiene instructions and the use of a manual toothbrush during the test period, with an adjunctive aPDT device (Lumoral®).\n\nIntervention Group B (Oral-B iO Powered Toothbrush) Standardized oral hygiene instructions and the use of an Oral-B iO powered toothbrush during the test period.\n\nControl Group Standardized oral hygiene instructions and the use of a manual TePe Select extra soft toothbrush during the test period.",[27,28],"Periodontal Diseases","Oral Halitosis",[30,31,32,33],"Mild Cognitive Impairment","Oral health","Quality of life","Powered toothbrush","NOT_YET_RECRUITING","2025-09-16",{"date":37,"type":38},"2025-09-19","ACTUAL",{"date":40,"type":21},"2025-10",{"date":42,"type":21},"2028-12",{"name":44,"class":45},"Blekinge Institute of Technology","OTHER"]