[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oral-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oral-health":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,19,0,[8,43,81,115,139,162,195,218,243,278,306,332,353,382,409,432,462,481,511],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100644831","large-language-models-for-dental-radiology-report-generation-from-structured-textual-data-100644831",false,"NCT07676318","Large Language Models for Dental Radiology Report Generation From Structured Textual Data","Evaluation of Large Language Models for Transforming Structured Dental Radiology Data Into Narrative Radiology Reports","DENT-LLM","Inclusion Criteria:\n\n* Dental radiology records based on dental X-ray examination performed on the basis of a written referral from a dentist or physician\n* Dental X-ray examinations performed for screening, diagnostic, or treatment-planning purposes\n* Records from patients with permanent dentition after completion of exfoliation\n\nExclusion Criteria:\n\n* Records from patients with mixed dentition before completion of exfoliation\n* Records with incomplete, ambiguous, or internally inconsistent structured dental radiology data preventing reliable report generation\n* Records with missing information required for evaluation of the generated report\n* Duplicate records from the same radiographic examination\n* Records in which anonymization or pseudonymization cannot be ensured","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","The purpose of this observational methodological study is to evaluate whether large language models can transform structured dental radiology data into clear narrative radiology reports. Large language models are computer programs that can generate text from information provided to them. In this study, the input will consist of organized dental radiology findings, such as chart-style or diagram-based information about teeth and surrounding structures.\n\nDental radiology reports are used by dentists and other health care providers to understand imaging findings and support clinical documentation. Preparing narrative reports may be time-consuming, and the wording of reports may vary between clinicians. This study will examine whether language-model-assisted report generation can produce reports that are complete, accurate, understandable, and clinically useful.\n\nThe study will compare reports generated with support from large language models with traditionally prepared reports. Researchers will also assess how the wording of the prompt and selected model parameters influence report quality. In addition, the study will analyze errors and safety risks in generated reports and evaluate whether such a system could be practical in a dental radiology workflow. The language model will not make treatment decisions, and generated reports will be used for research evaluation only.",[25,26,27,28,29],"Radiography","Oral Health","Large Language Model","Natural Language Processing (NLP)","Dentistry","NOT_YET_RECRUITING","2026-06-24",{"date":33,"type":34},"2026-06-30","ACTUAL",{"date":36,"type":21},"2026-06-29",{"date":38,"type":21},"2026-07-26",{"name":40,"class":41},"Hospital of the Ministry of Interior, Kielce, Poland","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":42},"100642058","comparison-of-patient-reported-comfort-between-two-clear-aligner-trimming-line-designs-a-split-mouth-study-100642058","NCT07660809","Comparison of Patient-Reported Comfort Between Two Clear Aligner Trimming-Line Designs: A Split-Mouth Study","Comparison of Patient-Reported Comfort Between Supragingival and Juxtagingival Clear Aligner Trimming-Line Designs: A Cross-Sectional, Within-Subject Split-Mouth Study","COMFORT-ALIGN","Inclusion Criteria:\n\n* Adolescent or adult patient (aged 15 years or older)\n* Active orthodontic treatment with clear aligners, including finishing (refinement) aligners\n* Wearing two clear aligners with different trimming-line designs, one per dental arch: a supragingival design on one arch and a juxtagingival design on the contralateral arch\n* At least 4 weeks of wear of the two designs at the time of questionnaire completion\n* Good treatment compliance\n* Willing and able to complete the online questionnaire and provide the required consent\n\nExclusion Criteria:\n\n* Mixed orthodontic treatment (aligners combined with fixed appliances)\n* Pre-existing neurological, cognitive, or speech disorders\n* Systemic conditions affecting the oral cavity (e.g., xerostomia, mucosal disorders)",true,"15 Years",{"count":54,"type":21},70,"* The trimming-line design of clear aligners (supragingival versus juxtagingival) is a routine clinical decision whose influence on patient-reported comfort has not been established; available evidence on aligner comfort derives almost exclusively from comparisons with fixed appliances.\n* This observational, cross-sectional study compares two clear aligner trimming-line designs with respect to patient-reported comfort: a supragingival design, whose edge rests on the marginal gingiva, and a juxtagingival design, whose edge follows the gingival contour without covering it. Because the two designs sit differently against the gingival soft tissue, they may be experienced differently during wear.\n* Participants are patients already wearing one trimming-line design on one dental arch and the other on the contralateral arch; each participant thus serves as their own control. After a minimum of four weeks of wear, participants complete a 20-item questionnaire once, rating the frequency of defined oral experiences for the maxillary and mandibular arch separately on a three-point ordinal scale (0 = none, 1 = occasional, 2 = frequent).\n* The questionnaire is anonymous; the design worn on each arch is identified from which of two identical forms a participant completes. Responses for the two designs are compared within each participant. The study evaluates whether trimming-line design is associated with differences in patient-reported comfort.",[57,58,26],"Patient Comfort","Malocclusion",[60,61,62,63,64,65,66,67,68,69,70,71],"clear aligners","trimming-line design","gingival margin","supragingival","juxtagingival","split-mouth design","patient-reported outcome","comfort","oral health-related quality of life","questionnaire","orthodontics","finishing orthodontic treatment","2026-06-18",{"date":74,"type":34},"2026-06-23",{"date":76,"type":21},"2026-07",{"date":78,"type":21},"2026-08",{"name":80,"class":41},"George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":88,"minAge":18,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":42},"100624727","oral-health-education-for-pregnant-women-100624727","NCT07413393","Oral Health Education for Pregnant Women","Knowledge of Oral Health in Pregnant Women: Effect of a Short Educational Intervention","Inclusion Criteria:\n\n* Women aged 18-45 who have recently given birth to healthy babies, either vaginally or by cesarean section.\n* Ability to understand and speak Spanish.\n\nExclusion Criteria:\n\n* Complications during pregnancy or delivery.\n* Newborns with major birth defects.\n* Participants who do not provide informed consent.","FEMALE","45 Years",{"count":91,"type":21},300,"INTERVENTIONAL",[94],"NA","The goal of this research is to investigate oral health knowledge in pregnant women receiving care at Hospital La Fe and to see whether a one-time informational intervention improves this knowledge. The main questions this research aims to answer are:\n\nWhat is the level of oral health knowledge among pregnant women attending Hospital La Fe?\n\nDoes a one-time informational intervention, delivered through a printed leaflet, improve oral health knowledge during pregnancy?\n\nWhat factors are related to differences in oral health knowledge among pregnant women?\n\nParticipants are pregnant women receiving care at Hospital La Fe. They will:\n\nComplete a questionnaire about their oral health knowledge.\n\nReceive a printed informational leaflet about oral health during pregnancy.\n\nComplete the same questionnaire again after a period of time to see if their knowledge has changed.\n\nResearchers will compare answers before and after the leaflet is provided to see whether oral health knowledge improves. They will also explore which personal or social factors are linked to different levels of oral health knowledge.",[97,26,98,99],"Knowledge","Pregnant Women","Intervention",[101,102,103,104],"oral health","knowledge","pregnant","improvement","RECRUITING","2026-06-05",{"date":108,"type":34},"2026-06-09",{"date":110,"type":34},"2026-02-15",{"date":112,"type":21},"2026-07-30",{"name":114,"class":41},"University of Valencia",{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":51,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":92,"phases":124,"briefSummary":125,"conditions":126,"keywords":127,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":42},"100633050","dysbiosis-of-methanogenic-archaea-and-nanoarchaea-in-the-oral-microbiome-100633050","NCT07521644","Dysbiosis of Methanogenic Archaea and Nanoarchaea in the Oral Microbiome","METHAORAL","Inclusion Criteria:\n\nCase selection criteria:\n\nCases are defined as subjects with oral health vulnerability\n\n* Men or women aged 60 years or older\n* and\u002For immunocompromised individuals without periodontal disease (gingivitis, periodontitis, and peri-implantitis) clinically diagnosed by the dentist during the consultation.\n* Patients who have received information about the study and have not expressed objection\n* Patients who are beneficiaries or eligible for a social security program Control group selection criteria Controls are defined as subjects without oral health vulnerability • Men and women under 60 years of age without periodontal disease (gingivitis, periodontitis, and peri-implantitis) clinically diagnosed by the dentist during the consultation.\n\nThe clinical examination allows for the diagnosis of the absence or presence of periodontal disease, with particular attention to: bleeding on probing, the depth of periodontal pocket(s), tooth mobility, bone destruction in furcation areas, and the assessment of radiographic bone level taking age into account.\n\nExclusion Criteria:\n\n* Patients who are currently excluded from another research protocol at the time the informed consent form is collected.\n* Subjects covered by Articles L1121-5 through L1121-8 of the Public Health Code (minors, adults under guardianship or conservatorship, patients deprived of their liberty, pregnant or breastfeeding women),\n* Men and women with periodontal disease (gingivitis, periodontitis, and peri-implantitis)\n* Men and women with any systemic disease\n* Men and women currently undergoing drug treatment",{"count":123,"type":21},250,[94],"Need to improve understanding of oral dysbiosis in the elderly and\u002For immunocompromised individuals (involvement of nanogenes in these dysbiosis) Comparison of dysbiosis identification between results from dental plaque samples and saliva samples (the saliva sample is non-operator-dependent due to its ease of collection). Comparison of the reliability of results obtained with this type of saliva sample versus results obtained with dental plaque samples, which are considered the reference sample type (Antézack 2023).\n\nPrimary objective To estimate the prevalence of dysbiosis in individuals with oral frailty versus individuals without oral frailty.\n\nIn this project:\n\n* Dysbiosis will be defined by the presence of Archaea (Bringuier 2013). For the primary objective, prevalence will be estimated based on dental plaque samples.\n* The population with oral frailty will be defined as individuals over 60 years of age or those with immunosuppression.\n\nHypothesis: The expected proportion of dysbiosis in the population with oral health vulnerability is 40%, whereas the expected proportion of dysbiosis in the population without oral health vulnerability is 20% (Li CL 2009).\n\nSecondary objectives Estimate the prevalence of dysbiosis in the two populations based on a saliva sample\n\n\\- Compare the results from the sample",[26],[128,129],"oral health issues","without oral health issues","2026-04-08",{"date":132,"type":34},"2026-04-13",{"date":134,"type":21},"2026-09-01",{"date":136,"type":21},"2029-12-01",{"name":138,"class":41},"Assistance Publique Hopitaux De Marseille",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":145,"eligibilityCriteria":146,"healthyVolunteers":51,"sex":17,"minAge":147,"maxAge":4,"enrollmentInfo":148,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":150,"conditions":151,"keywords":152,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":160,"locationsCount":42},"100631990","validation-of-the-turkish-version-of-the-oral-assessment-sheet-100631990","NCT07507864","Validation Of The Turkish Version Of The Oral Assessment Sheet","Turkish Validity And Reliability Study Of The Oral Assessment Sheet (OAS)","OAS-TR","Inclusion Criteria:\n\n* Age 60 years or older\n* Ability to understand Turkish\n* Voluntary participation and provision of written informed consent\n* Ability to undergo oral examination and assessment\n* Adequate cognitive and psychological status\n\nExclusion Criteria:\n\n* Individuals who refuse to participate in the study\n* Individuals who withdraw from the study during the research process\n* Individuals with severe cognitive impairment preventing completion of the assessment\n* Individuals with conditions preventing oral examination","60 Years",{"count":149,"type":21},99,"The aim of this observational study is to evaluate the validity and reliability of the Turkish version of the Oral Assessment Sheet (OAS). The OAS is a clinical assessment tool developed to evaluate oral health conditions such as lips, tongue, mucosa, saliva, swallowing, and voice.\n\nThis study will investigate whether the Turkish version of the OAS is a valid and reliable tool for assessing oral health status in clinical practice. Participants will undergo oral assessment using the Turkish version of the OAS. Statistical analyses will be performed to determine the validity and reliability of the scale.\n\nThe results of this study are expected to provide a standardized oral assessment tool that can be used in Turkish clinical settings.",[26],[153],"Oral Assessment Sheet OAS","2026-03-27",{"date":156,"type":34},"2026-04-02",{"date":158,"type":34},"2026-02-26",{"date":76,"type":21},{"name":161,"class":41},"Necmettin Erbakan University",{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":168,"eligibilityCriteria":169,"healthyVolunteers":51,"sex":17,"minAge":170,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":174,"conditions":175,"keywords":179,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":194},"100569556","food-typologies-and-multidimensional-phenotyping-of-elderly-in-auvergne-rhne-alpes-partage-100569556","NCT06695780","Food Typologies and Multidimensional Phenotyping of Elderly in Auvergne-Rhône-Alpes (Part'AGE)","Exploration Des Typologies Alimentaires et caractérisation Par un phénotypage Multidimensionnel d'Une Population de Personnes âgées de la région Auvergne-Rhône Alpes","Part'AGE","Inclusion Criteria:\n\n* Male or female (balanced sex ratio or at least 40% male to 60% female) in complete autonomy at home.\n* 55 to 75 years old, including the limits\n* 20 ≤ BMI ≤35 kg\u002Fm2\n* Available to carry out the entire protocol, including self-sampling (not sensitive to the sight of one's own blood for example) and agreeing to stop taking food supplements during the study.\n* Having a scale available: at home, pharmacy, family, etc.\n* Having internet access and a device with a screen and camera (PC, tablet, smartphone, etc.) at home or able to go to a project partner (CCAS, Point France Service, Community, Association, etc.) that can provide this access\n* Subject agreeing to give written consent (by phone or videoconferencing), and registration in the national file of volunteers who participate in research\n* Person declaring to be subject to a social security scheme.\n\nExclusion Criteria:\n\n* Weight loss ≥ 5% in 1 month or ≥ 10% in 6 months or ≥ 10% compared to usual weight\n* Treated diabetes\n* Sub-acute pathology (flu, gastroenteritis, bacterial infection, etc.) or trauma (fracture, surgical intervention, etc.) in the 30 days prior to inclusion.\n* Hepatocellular insufficiency,\n* Heart failure with decompensation,\n* Renal insufficiency (clearance \\\u003C30 ml\u002Fmin)\n* Chronic anti-inflammatory treatment, long-term corticosteroid therapy \\> 1 month, infiltration\n* Progressive pathology at the time of inclusion (cancer, etc.)\n* Gastrointestinal pathology deemed incompatible with the protocol\n* Unstable thyroid diseases\n* Recent change in eating habits in the last 30 days (weight loss diet, veganism, intermittent fasting, ketogenic diet, etc.)\n* Intense physical activity (activity causing shortness of breath and sweating) \\> 10 hours per week\n* Person in a period of exclusion from the National File of Healthy Volunteers\n* Subject under guardianship, curator-ship, deprived of liberty or under judicial protection","55 Years","75 Years",{"count":173,"type":21},1000,"To better understand how diet influences health during aging, the French National Research Institute for Agriculture, Food and the Environment (INRAE) is working with the Gérontopôle Auvergne-Rhône-Alpes on a project called Part'AGE. Part'AGE is a participatory research project where researchers want to recruit 1,000 people aged between 55 and 75 years, men and women, living in Auvergne-Rhône-Alpes in urban or rural areas. The goal is to study eating habits and state of health. To do this, researchers will examine many factors that can influence them, such as physical activity, overall health, consumption patterns or territories. Researchers will collect detailed information to classify participants into different groups (food typologies) based on their eating habits and state of health. With this distribution, the goal is to be able to give each group personalized nutritional advice to age in better health.\n\nTo participate in the study, the participants will need to collect a few drops of blood from the end of the finger, a urine sample, and do some tests (mobility, oral health). It will also be necessary to fill out questionnaires on eating habits, physical activity, and other aspects that may influence health. The benefices for to participants will be to contribute to nutrition research and to receive personalized feedback and advices on eating habits.",[176,177,178,26],"Nutritional Assessment","Physical Activity","Health",[180,181,182,183,184,185],"eating behaviors","elderly","health","phenotyping","food typologies","prevention","2026-03-24",{"date":154,"type":34},{"date":189,"type":34},"2025-02-03",{"date":191,"type":21},"2028-02",{"name":193,"class":41},"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement",2,{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":51,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":202,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":204,"conditions":205,"keywords":206,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":4},"100621742","egyptian-dental-professionals-perspectives-on-the-oral-microbiome-and-exosomes-100621742","NCT07374575","Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes","Assessment of Knowledge, Attitudes, and Perceived Barriers Regarding the Oral Microbiome and Exosomes Among Egyptian Dental Professionals: A Cross-Sectional Questionnaire Study","Inclusion Criteria:\n\n* Licensed dentists practicing in Egypt (general dentists and all specialties)\n* age ≥18.\n\nExclusion Criteria:\n\n* Undergraduate students\u002Finterns without a license\n* dentists currently practicing abroad; duplicate entries.",{"count":203,"type":21},500,"This study employs a structured, validated questionnaire as the index test to objectively assess dental professionals' knowledge of the oral microbiome and exosomes, alongside attitudes, readiness, and perceived barriers. The primary aim is to develop and compare Microbiome Knowledge Scores (MKS) and Exosome Knowledge Scores (EKS) across dental specialties, workplace settings, and years of practice. Secondary aims include evaluating attitudes and perceived barriers, assessing the relationship between self-rated and objective knowledge, and identifying predictors of higher knowledge levels. The study tests the null hypotheses that MKS\u002FEKS do not differ across demographic or practice characteristics and that self-rated knowledge does not correlate with objective knowledge.",[26],[207,208],"oral microbiome","exosomes","2026-03-17",{"date":211,"type":34},"2026-03-19",{"date":213,"type":21},"2027-01-20",{"date":215,"type":21},"2027-01-30",{"name":217,"class":41},"Cairo University",{"id":219,"slug":220,"hasResults":11,"nctId":221,"briefTitle":222,"officialTitle":223,"acronym":4,"eligibilityCriteria":224,"healthyVolunteers":11,"sex":88,"minAge":18,"maxAge":225,"enrollmentInfo":226,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":227,"conditions":228,"keywords":229,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":4},"100373140","structural-and-intermediary-social-determinants-of-oral-health-among-egyptian-women-100373140","NCT04138550","Structural and Intermediary Social Determinants of Oral Health Among Egyptian Women","Exploring the Structural and Intermediary Social Determinants of Oral Health Among Egyptian Women: A Cross-Sectional Study","Inclusion Criteria:\n\n* Egyptian women in child bearing age (18-49 years) attending one of the governmental primary healthcare units.\n\nExclusion Criteria:\n\n* Women who recently moved from one place of residence to another.\n* Women attending the dental clinic at one of the primary health units selected for the survey.\n* Pregnant Women.\n* Completely Edentulous Women.\n* Women with mental or psychological issues.","49 Years",{"count":91,"type":21},"Globally, there is substantial evidence indicating that low household income, lack of education, poor living conditions and inadequate psycho-social social support are potential risk factors for morbidity and premature death. Despite that, worldwide, there is scarcity in evidence on potential social determinants of oral health among different population groups.The study aims To identify the potential social determinants with an influence on oral health status of Egyptian women.",[26],[230,231,232,233],"Social determinants","Oral health","Women","Egypt","2026-01-26",{"date":236,"type":34},"2026-01-27",{"date":238,"type":21},"2027-12-01",{"date":240,"type":21},"2028-12",{"name":242,"class":41},"Misr International University",{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":248,"acronym":249,"eligibilityCriteria":250,"healthyVolunteers":51,"sex":17,"minAge":18,"maxAge":251,"enrollmentInfo":252,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":254,"conditions":255,"keywords":258,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":42},"100615637","oral-indicators-for-ed-screening-100615637","NCT07295197","Oral Indicators for ED Screening","Analysis of Oro-Dental Manifestations for the Screening of Eating Disorders.","OHEDS","Inclusion Criteria:\n\n* Age between 18 and 40 years\n* Presence of at least 20 permanent teeth (third molars excluded)\n* Both males and females are eligible\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Use of systemic antibiotics within the previous month\n* Active orthodontic treatment\n* Presence of systemic diseases that may affect oral conditions, including: diabetes, ulcerative colitis, Crohn's disease, Sjögren's syndrome, HIV infection, hematologic diseases, neoplasms\n* Mental disorders or neuromotor deficits that may interfere with the oro-dental clinical signs evaluated by the OHEDs Checklist\n* Use of xerogenic medications or drugs that may alter salivary flow or oral\u002Fperioral mucosal conditions, including: antihypertensives, beta-blockers, non-steroidal anti-inflammatory drugs (NSAIDs), antiparkinson medications, anxiolytics, antidepressants, neuroleptics","40 Years",{"count":253,"type":21},461,"The main objective of this research project is to explore the capability of a standardized, evidence-based study tool (the OHEDs Checklist) in the early identification of oro-dental manifestations potentially indicative of an eating disorder.\n\nThe secondary objective is to evaluate the sensitivity and specificity of the OHEDs Checklist in comparison with validated screening instruments for eating disorders, namely the ESP, SCOFF and DEQ questionnaires.",[256,26,257],"Eating Disorders","Eating Disorders Symptoms",[259,231,260,261,262,263,264,265,266,267,268],"Eating disorders","Dental erosion","Oro-dental manifestations","Disordered eating","Screening tool","SCOFF questionnaire","ESP questionnaire","DEQ questionnaire","OHEDs Checklist","OHEDs","2025-12-08",{"date":271,"type":34},"2025-12-19",{"date":273,"type":34},"2025-11-14",{"date":275,"type":21},"2026-04-14",{"name":277,"class":41},"University of Bologna",{"id":279,"slug":280,"hasResults":11,"nctId":281,"briefTitle":282,"officialTitle":283,"acronym":4,"eligibilityCriteria":284,"healthyVolunteers":51,"sex":17,"minAge":285,"maxAge":286,"enrollmentInfo":287,"targetDuration":4,"studyType":92,"phases":289,"briefSummary":290,"conditions":291,"keywords":295,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":300,"completionDateStruct":302,"leadSponsor":304,"locationsCount":42},"100605284","ai-toothbrush-and-visual-pedagogy-to-improve-oral-hygiene-in-children-with-autism-spectrum-disorder-100605284","NCT07160517","AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder","Effectiveness of an Artificial Intelligence-Enabled Electric Toothbrush and Visual Pedagogy Materials on Oral Hygiene of Children With Autism Spectrum Disorder","Inclusion Criteria:Children aged 5-13 years with a prior diagnosis of autism spectrum disorder (ASD) level 1 , 2 or 3 confirmed by a neuropediatrician.\n\nChild must be accompanied by a primary caregiver (≥18 years old) responsible for daily oral hygiene.\n\nCaregiver must have access to a smartphone or computer to interact with the digital platform.\n\nWritten informed consent (TCLE) from the caregiver and assent (TALE) from the child.\n\n\\-\n\nExclusion Criteria:Severe systemic medical conditions that contraindicate participation in clinical oral evaluations.\n\nChildren with advanced periodontal disease or other oral conditions requiring urgent dental treatment.\n\nCaregivers who are unable or unwilling to use basic digital platforms (smartphone, tablet, or computer).\n\nFamilies who decline participation at any stage of the study.\n\n\\-","5 Years","13 Years",{"count":288,"type":21},50,[94],"This randomized clinical trial evaluates the effectiveness of an AI-enabled electric toothbrush and visual pedagogy materials in improving oral hygiene among children with autism spectrum disorder (ASD). The study compares plaque control, gingival health, and adherence between children using a manual toothbrush with visual pedagogy support and those using an AI-enabled electric toothbrush with app-based monitoring.",[292,293,26,294],"Autism Spectrum Disorder","Child","Artificial Intelligence",[296],"Autism Spectrum Disorder, Toothbrushing, Oral Hygiene, Artificial Intelligence.","2025-08-29",{"date":299,"type":34},"2025-09-08",{"date":301,"type":21},"2025-10-01",{"date":303,"type":21},"2027-02-10",{"name":305,"class":41},"University of Sao Paulo",{"id":307,"slug":308,"hasResults":11,"nctId":309,"briefTitle":310,"officialTitle":311,"acronym":4,"eligibilityCriteria":312,"healthyVolunteers":51,"sex":17,"minAge":18,"maxAge":313,"enrollmentInfo":314,"targetDuration":4,"studyType":92,"phases":316,"briefSummary":317,"conditions":318,"keywords":320,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":323,"lastUpdatePostDateStruct":324,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":42},"100589607","evaluating-the-impact-of-various-dietary-nitrate-supplements-on-oral-health-100589607","NCT06956612","Evaluating the Impact of Various Dietary Nitrate Supplements on Oral Health","Evaluating the Impact of Various Dietary Nitrate Supplementation Forms on Microbiological Markers of Oral Health and Acceptability Among Adult Participants","Inclusion Criteria:\n\n* Healthy volunteers\n* Aged 18 - 65 years.\n\nExclusion Criteria:\n\n* Aged less than 18 or more than 65 years old.\n* Current smoking\n* Alcohol consumption of greater than14 units per week.\n* Diagnosis of a chronic disease (e.g., cardiovascular disease, diabetes, cancer, or gastrointestinal disorders), including oral diseases.\n* Use of antibiotics within the past three months or medications\u002Fnutritional supplements that may affect the oral cavity (e.g., prebiotics, probiotics, or hormone replacement therapy).\n* Regular use of antibacterial mouthwash or xylitol-containing products (e.g., gum or toothpaste) or the use of proton pump inhibitors.\n* Presence of braces\u002Finvisalign or dentures.\n* Known allergy to any food, including beets\n* Adherence to dietary restrictions (e.g., weight loss diet)\n* Eating disorders that may limit participation in the study.\n* Currently pregnant, breastfeeding or trying to become pregnant.\n* Participation in other studies.","65 Years",{"count":315,"type":21},60,[94],"This study aims to investigate the effects of different dietary nitrate supplements, versus placebo, on microbiological and immunological markers associated with oral health in people aged 18-65 years.\n\nThe main research questions are:\n\n* How do different dietary nitrate supplements (beetroot crystals vs. beetroot juice) affect oral health markers, including salivary pH and oral microbiome composition?\n* What is the acceptability and ease of integrating one of dietary nitrate supplements, made from beetroot but processed as freeze dried crystals or juice, into the daily diet?\n\nTo answer these questions, the study will compare results from three groups of participants, who will be randomly assigned to one of the following study arms:\n\nGroup 1: The control group will consume a placebo beetroot supplement completely free of nitrate in juice form.\n\nGroup 2: The beetroot juice group will consume a beetroot supplement standardised to contain \\~ 400 mg of nitrate in juice form.\n\nGroup 3: The beetroot crystals group will consume a beetroot supplement standardised to contain \\~400 mg of nitrate in freeze dried crystal form.\n\nThe study will follow a randomised, single-blind, placebo-controlled, parallel design, and the intervention will last for four weeks. Data will be collected by providing pre- and post-intervention saliva samples tongue swabs, and various questionnaires will be completed at baseline and at the end of the study. In addition, at the end of the second week of the intervention period, participants will be asked to collect a saliva sample over three consecutive days at home.",[26,319],"Dietary Nitrate",[321,101,322,207],"Dietary nitrate","salivary acidity","2025-05-27",{"date":325,"type":34},"2025-05-28",{"date":327,"type":34},"2025-05-23",{"date":329,"type":21},"2026-04",{"name":331,"class":41},"Shatha Alhulaefi",{"id":333,"slug":334,"hasResults":11,"nctId":335,"briefTitle":336,"officialTitle":336,"acronym":4,"eligibilityCriteria":337,"healthyVolunteers":51,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":338,"targetDuration":4,"studyType":92,"phases":340,"briefSummary":341,"conditions":342,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":42},"100544041","a-pilot-study-of-a-commercially-available-oil-rinse-product-periopull-on-markers-of-dental-health-100544041","NCT06363721","A Pilot Study of a Commercially-available Oil Rinse Product (PerioPull™) on Markers of Dental Health","Inclusion Criteria:\n\n* Plaque index of at least 1\n* Gingival index of at least 1\n* Pocket depth no greater than 5 mm\n* Able to understand and write English\n* Voluntarily consent to the study and understand its nature and purpose including potential risks and side effects\n* Maintain current dental hygiene routine\n* Bleeding on probing\n\nExclusion Criteria:\n\n* Current daily use of any products containing the nutrients and\u002For herbs in the study product\n* Known allergies to any substance in the study product\n* Current daily tobacco smoker\n* Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks\n* Active oral infection (ie. herpes, candida)\n* Recently on antibiotics (past 3 months)\n* Undergone recent periodontal therapy (last 6 months)",{"count":339,"type":21},18,[94],"The primary purpose of this study is to evaluate the impact of a commercially-available oil rinse product (PerioPull™) on parameters of dental health among a sample of adults. PerioPull™ is commercially available and sold primarily from clinicians' offices.\n\nA 12-week pilot study will be conducted to achieve the purpose of this study. The research team hypothesizes that PerioPull™ will improve a variety of validated markers of dental health that are commonly used in clinical practice.",[26],"2025-05-12",{"date":345,"type":34},"2025-05-14",{"date":347,"type":34},"2024-07-10",{"date":349,"type":21},"2025-08",{"name":351,"class":352},"Designs for Health","INDUSTRY",{"id":354,"slug":355,"hasResults":11,"nctId":356,"briefTitle":357,"officialTitle":358,"acronym":4,"eligibilityCriteria":359,"healthyVolunteers":51,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":360,"targetDuration":4,"studyType":92,"phases":362,"briefSummary":363,"conditions":364,"keywords":368,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":380,"locationsCount":42},"100462990","prosenior-prevention-of-pressure-ulcers-malnutrition-poor-oral-health-and-falls-among-older-persons-receiving-municipal-health-care-and-are-registered-in-the-quality-registry-senior-alert-100462990","NCT05308862","PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert","Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert","Inclusion Criteria:\n\n* Nursing homes registering in Senior Alert, which is a national quality registry\n\nExclusion Criteria:\n\n* not meetin inclusion criteria",{"count":361,"type":21},330,[94],"Inclusion criteria for study I and II is nurse aides, registered nurses and managers working in nursing homes who register in Senior Alert. To develop an intervention aiming to reduce the risk of pressure ulcers, malnutrition, poor oral health and falls among older persons in nursing homes, workshops will be conducted in collaboration with nurse aides, registered nurses and managers (study I). Cluster randomization is going to take place via a computerized program prior to the workshops meaning that only those nurse aides, registered nurses and managers working in nursing homes allocated to the intervention group are going to develop an intervention together with the research group and then test it (study II). The remaining nurse aides, registered nurses and managers working in nursing homes in the control group continue with regular care.",[365,366,367,26],"Fall","Pressure Ulcer","Malnutrition",[369,370,371,372],"Prevention","Older people","Nursing care","Complex intervention","2025-05-07",{"date":375,"type":34},"2025-05-09",{"date":377,"type":34},"2022-01-19",{"date":379,"type":21},"2025-12-31",{"name":381,"class":41},"Malmö University",{"id":383,"slug":384,"hasResults":11,"nctId":385,"briefTitle":386,"officialTitle":386,"acronym":4,"eligibilityCriteria":387,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":388,"enrollmentInfo":389,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":391,"conditions":392,"keywords":393,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":403,"completionDateStruct":405,"leadSponsor":407,"locationsCount":42},"100590567","a-study-on-the-correlation-between-oral-health-and-delirium-in-surgical-inpatients-100590567","NCT06969092","A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients","Inclusion Criteria:\n\n* Patients aged ≥18 years scheduled for elective cardiac or thoracic surgery requiring endotracheal intubation.\n\nPatients without consciousness impairment, able to cooperate with the investigation.\n\nPatients or their legal guardians informed about the study's purpose, methodology, and content, with signed informed consent forms.\n\nExclusion Criteria:\n\n* Patients with pre-existing oral conditions (e.g., xerostomia, oral mucosal lesions) prior to mechanical ventilation.\n\nPatients with a history of radiotherapy, chemotherapy, or corticosteroid use before surgery.\n\nPatients experiencing intraoperative mortality.","90 Years",{"count":390,"type":21},550,"Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or postoperative stress . As the most common complication in hospitalized patients, delirium is highly prevalent among elderly surgical populations, with postoperative delirium (POD) occurring in 7.5%-27.5% of cases, and rates rising to 50%-70% in intensive care unit (ICU) patients . Its onset is closely associated with poor prognoses, including long-term postoperative cognitive decline , increased mortality, prolonged hospitalization, and elevated healthcare costs (annual costs in the United States ranging from 38billionto152 billion) . Early prevention and screening of POD are therefore critical to improving patient outcomes and reducing healthcare burdens.\n\nSurgical patients' oral health issues exhibit multifactorial pathogenesis: intrinsic factors (e.g., age-related tooth loss, malnutrition-induced mucosal repair impairment, and chewing dysfunction due to reduced skeletal muscle mass) and iatrogenic factors (e.g., endotracheal intubation trauma, salivary secretion suppression from analgesics, and inadequate perioperative oral care). Poor oral health in hospitalized patients is often attributable to aging, physical dependence, cognitive decline, malnutrition, low skeletal muscle mass\u002Fstrength, and comorbidities. The recently proposed concept of \"Oral Frailty\"-a progressive decline in oral structure and function-strongly predicts physical frailty, dysphagia, malnutrition, long-term care needs, and mortality in community-dwelling older adults\n\nThe impact of oral health on cognitive function may involve three pathways :\n\nMechanical pathway: Tooth loss disrupts masticatory motor function, reduces cerebral blood flow, and diminishes afferent stimulation from peripheral receptors (e.g., periodontal ligaments), leading to weakened neural connectivity and regional brain atrophy.\n\nNeurodegenerative pathway: Tooth loss accelerates neuronal damage via apoptosis and mitophagy, increasing amyloid-beta deposition in the brain.\n\nInflammatory\u002Fmetabolic pathway: Systemic inflammation, metabolic dysregulation, microbial-gut-brain axis interactions, and activation of microglia\u002Fastrocytes drive neuroinflammatory cascades in the central nervous system.\n\nGiven these connections, oral frailty may act as an independent risk factor distinct from general frailty and a potential contributor to POD. These findings suggest that oral frailty could serve as a unique biomarker for perioperative neurocognitive disorders, mediating their pathogenesis. Systematic investigation into the spatiotemporal relationship and mechanisms linking oral health to POD in surgical patients holds significant clinical value for developing multimodal prevention strategies.",[26],[26,394,395,396,397,398,399],"Oral Frailty","Surgical","Surgery","Delirium","Endotracheal Intubation","Cognitive Function","2025-05-06",{"date":402,"type":34},"2025-05-13",{"date":404,"type":21},"2025-05-25",{"date":406,"type":21},"2026-03-25",{"name":408,"class":41},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine",{"id":410,"slug":411,"hasResults":11,"nctId":412,"briefTitle":413,"officialTitle":414,"acronym":4,"eligibilityCriteria":415,"healthyVolunteers":51,"sex":88,"minAge":416,"maxAge":417,"enrollmentInfo":418,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":420,"conditions":421,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":426,"completionDateStruct":428,"leadSponsor":430,"locationsCount":4},"100589092","the-effect-of-body-mass-index-on-taste-perceptionsalivary-hormones-and-oral-health-status-100589092","NCT06949917","The Effect of Body Mass Index on Taste Perception,Salivary Hormones and Oral Health Status","Taste Perception,Oral Health Status and Selectied Salivary Hormones in Relation to Body Mass Index Among Agroup of Iraqi Adolescent Girls.","Inclusion Criteria:\n\n* female\n* 16-17 years old\n* subject with no systemic diseas.\n\nExclusion Criteria:\n\n* medically compressed patient\n* patient with systemic disease","16 Years","17 Years",{"count":419,"type":21},90,"the goal of the study is to test the effect of body mass index on adolesent Iraqi student girls by measuring salivary hormones (ghrelin,leptin,resistin)and measuring oral health by plague index score() and taste perception score () 90 female subject will be enrolled in this study between 16-17 years old,30 subjects with normal body weight ,30 subject overweight ,and 30 subject with obeiece group catogerize by body mass index according to age.\n\nthe methed of the study is by taking Saliva sample from the subject , taste perception score and oral health measure.",[26,422],"Tast Perference","2025-04-22",{"date":425,"type":34},"2025-04-29",{"date":427,"type":21},"2025-04-30",{"date":429,"type":21},"2025-06-30",{"name":431,"class":41},"Al-Mustansiriyah University",{"id":433,"slug":434,"hasResults":11,"nctId":435,"briefTitle":436,"officialTitle":437,"acronym":4,"eligibilityCriteria":438,"healthyVolunteers":51,"sex":17,"minAge":439,"maxAge":440,"enrollmentInfo":441,"targetDuration":4,"studyType":92,"phases":443,"briefSummary":444,"conditions":445,"keywords":449,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":453,"lastUpdatePostDateStruct":454,"startDateStruct":456,"completionDateStruct":458,"leadSponsor":460,"locationsCount":42},"100586213","sport-mouthguards-devices-for-preventing-dental-injuries-in-sports-100586213","NCT06912451","Sport Mouthguards: Devices for Preventing Dental Injuries in Sports","Sport Mouthguards: Devices for Preventing Dental and Alveolar Injuries in Sports - A Longitudinal Study","Inclusion Criteria:\n\n* Children, adolescents, and adults aged 7 to 30 years, with no systemic health issues, of both genders;\n* Engaging in sports practice at least twice a week.\n\nExclusion Criteria:\n\n* Presence of cavitated dental caries and\u002For periodontitis;\n* Angle Class III malocclusion with negative anterior overjet;\n* Presence of non-removable prostheses or any other accessory in the upper or lower arch that may interfere with the adaptation of the mouthguard;\n* Use of medications that may interfere with any salivary parameters;\n* Children, adolescents, and adults with neurological disorders or communication difficulties.","7 Years","30 Years",{"count":442,"type":21},136,[94],"Objective: To evaluate the impact of mouthguards (MG) on acceptability, incidence of soft tissue injuries, periodontal and salivary parameters, as well as on the perception of the body in sports practice (PeCoPes) and on the quality of life of athletes, and evaluate the consequences of use on the characteristics, state of conservation, and biological and physical properties of the MG itself. Methodology: This is a longitudinal study that will include children, adolescents, and adults aged 7 to 30 years who practice sports and require MGs. Sociodemographic data, medical history, dental history, dietary habits, and sports practice data will be collected. Participants will undergo a complete oral clinical examination. Data on knowledge of traumatic dental injuries (TDI) and MGs will also be collected. Before the MG is delivered, immediately after installation, and at 1, 3, and 6 months after use, the following parameters will be evaluated: presence of mucosal injuries, visible plaque index, gingival bleeding index, salivary flow, salivary pH, buffering capacity, and salivary microorganism count. Acceptability will be evaluated before the MG is delivered, immediately after delivery, and at 1, 3, and 6 months after use. PeCoPes and quality of life will be assessed before, 1, 3, and 6 months after MG use. The MG will be evaluated for bacterial contamination, delamination, roughness, dimensional changes related to shape and thickness, color change, and conservation status. The data will be tabulated and analyzed using SPSS 21.0, and appropriate statistical tests (p\\\u003C0.05) will be performed according to the study objectives.",[26,446,447,448],"Dental Trauma","Oral Health Knowledge, Attitude and Practice Among Patients","Mouth Protectors",[448,450,451,446,452,231],"Athletes","Sports","Questionnaire","2025-03-31",{"date":455,"type":34},"2025-04-04",{"date":457,"type":34},"2024-06-01",{"date":459,"type":21},"2025-12-26",{"name":461,"class":41},"Universidade Federal do Rio de Janeiro",{"id":463,"slug":464,"hasResults":11,"nctId":465,"briefTitle":466,"officialTitle":467,"acronym":4,"eligibilityCriteria":468,"healthyVolunteers":51,"sex":17,"minAge":18,"maxAge":147,"enrollmentInfo":469,"targetDuration":285,"studyType":22,"phases":4,"briefSummary":470,"conditions":471,"keywords":472,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":473,"lastUpdatePostDateStruct":474,"startDateStruct":476,"completionDateStruct":478,"leadSponsor":480,"locationsCount":42},"100581694","analysis-of-oral-health-of-students-and-former-students-of-undergraduate-and-postgraduate-programs-at-the-university-of-so-paulo-100581694","NCT06853639","Analysis of Oral Health of Students and Former Students of Undergraduate and Postgraduate Programs at the University of São Paulo.","Analysis of Oral Health of Students and Former Students of Undergraduate and Postgraduate Programs at the University of São Paulo: A Cohort Study","Inclusion Criteria:\n\n* 1\\. Current and former undergraduate and postgraduate students of the University of São Paulo.\n\nExclusion Criteria:\n\n* 1\\. Individuals who do not consent to participate.",{"count":91,"type":21},"This study aims to evaluate oral and systemic health conditions among students and former students of undergraduate and postgraduate programs at the University of São Paulo over five years. The primary focus is to understand how oral health impacts academic performance and attendance, providing insights for health promotion strategies within the university community.",[26],[101],"2025-03-05",{"date":475,"type":34},"2025-03-06",{"date":477,"type":21},"2025-03",{"date":479,"type":21},"2034-02",{"name":305,"class":41},{"id":482,"slug":483,"hasResults":11,"nctId":484,"briefTitle":485,"officialTitle":486,"acronym":4,"eligibilityCriteria":487,"healthyVolunteers":11,"sex":17,"minAge":313,"maxAge":4,"enrollmentInfo":488,"targetDuration":4,"studyType":92,"phases":490,"briefSummary":491,"conditions":492,"keywords":495,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":502,"lastUpdatePostDateStruct":503,"startDateStruct":505,"completionDateStruct":507,"leadSponsor":509,"locationsCount":4},"100556806","the-effects-of-technological-oral-health-management-100556806","NCT06529900","The Effects of Technological Oral Health Management","The Effects of Technological Oral Health Management on Improving Oral Health, Eating Ability, Nutritional Status, and Physical Function of the Elderly in the Community After Wearing Removable Dentures: An Example of the Agricultural County","Inclusion Criteria:\n\n1. residing in Chiayi County who are 65 years of age or older\n2. capable of self-care, conscious\n3. able to communicate in Mandarin and Taiwanese.\n\nExclusion Criteria:\n\n1. non-residents of Chiayi County\n2. unable to take care of themselves or are unconscious\n3. demented or mentally challenged and are unable to cooperate",{"count":489,"type":21},112,[94],"The goal of interventional study is to for the elderly who have poor chewing and eating ability after installing removable dentures through the intervention of oral mastication training and texture and diet education, the effects on oral health, eating ability, nutrition, and physical function changes are confirmed in Elderly individuals residing in Chiayi County who are 65 years of age or older, capable of self-care, conscious, and able to communicate in Mandarin and Taiwanese. The main question it aims to answer is:\n\n•Are there significant benefits to oral health, eating ability, nutrition, and physical function through the intervention of oral mastication training and texture and diet education? Researchers will compare changes in oral health, eating ability, nutrition, and physical functioning results to see if oral mastication training is effective.\n\nParticipants will:\n\n* Experimental group: oral mastication training and texture and diet education.\n* Control group: only texture and diet education.\n* Cases were tracked in month 1 and will be tracked again in month 6.",[26,367,493,494],"Dysphagia","Sarcopenia",[496,101,497,498,499,500,501],"the elderly in the community","nutrition","eating ability","physical function","technological oral health management","dentures","2024-07-29",{"date":504,"type":34},"2024-07-31",{"date":506,"type":21},"2024-09-02",{"date":508,"type":21},"2025-07-31",{"name":510,"class":41},"Chang Gung University of Science and Technology",{"id":512,"slug":513,"hasResults":11,"nctId":514,"briefTitle":515,"officialTitle":516,"acronym":517,"eligibilityCriteria":518,"healthyVolunteers":51,"sex":17,"minAge":519,"maxAge":520,"enrollmentInfo":521,"targetDuration":4,"studyType":92,"phases":523,"briefSummary":524,"conditions":525,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":526,"lastUpdatePostDateStruct":527,"startDateStruct":529,"completionDateStruct":531,"leadSponsor":533,"locationsCount":194},"100497531","caries-obesity-prevention-in-children-by-modifying-risk-behaviors-among-parents-with-immigrant-background-cop-study-100497531","NCT05758454","Caries-Obesity Prevention in Children by Modifying Risk Behaviors Among Parents With Immigrant Background-COP Study","Innovation Project Innovation Project for the Public Sector: Caries-Obesity Prevention in Children by Modifying Risk Behaviors Among Parents With Immigrant Background-COP Study","COP","Inclusion Criteria:\n\n* Parents having newborn infants (0-6 months) with Non-Western immigrant background\n\nExclusion Criteria:\n\n* The parents will be excluded if they cannot understand and sign a consent form and are not willing to follow the the clinical trial procedures.","20 Years","50 Years",{"count":522,"type":21},400,[94],"Immigrants constitute 18.2 % of the whole population in Norway. Health inequalities were previously reported, and immigrant status has been associated with a high risk of caries and obesity in children. Lack of parental knowledge, poor communication, ethnic and cultural differences are suggested to be reasons for the observed discrepancies. Therefore, research-based knowledge about the social, psycho-social and cognitive factors, that direct health \u002F dental health-related behavior in families with an immigrant background is needed.\n\nAims The main goal of this project is to assess attitudes and behaviors related to health\u002Foral health among immigrant parents with newborn children (0-6 months). Develop an intervention programs with the aim of increasing the parent's knowledge of the children's oral hygiene\u002Ffood habits and to evaluate in a follow-up study the effect of intervention on parents' knowledge and attitude with regard to dental caries and obesity.\n\nMethods Parents with immigrant status will be recruited from primary health centers located in the western part of Norway when meeting for children's vaccination. Primary health care centers will be conveniently divided into an intervention and control group. Intervention in form of a health\u002Fdental health information translated into different native language will be provided for the intervention group. The control group will receive regular primary care health information. Efficacy of the intervention will be assessed as differences in change scores between intervention and control group regarding parental attitudes, knowledge and behaviors and children's quality of life related to health and oral health, children's body mass index and early childhood caries. Objective of this work are consistent with community needs to eliminate health\u002Fsocial inequalities and it is anticipated that a culturally adapted interventions can be implemented among immigrant families at a moderate cost.",[26],"2023-02-24",{"date":528,"type":34},"2023-03-07",{"date":530,"type":34},"2018-01-31",{"date":532,"type":21},"2026-06",{"name":534,"class":41},"Oral Health Centre of Expertise in Western Norway"]