[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oral-thrush\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oral-thrush":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100497742","oropharyngeal-candidiasis-opc-and-s-ecc-100497742",false,"NCT05761197","Oropharyngeal Candidiasis (OPC) and S-ECC","Association Between Early Candida Infection (Oral Thrush) and Severe Early Childhood Caries (S-ECC)","Oral-Thrush","Inclusion Criteria:\n\n* Male or female individuals at the age of 9-15-month-old\n* Must have at least one fully erupted tooth at baseline visit\n* Parent\u002Fguardian willing and able to provide informed consent\n* With or without a history of OPC (the study team will enroll 35 participants with and 35 participants without a history of OPC)\n\nExclusion Criteria:\n\n* Presence of a systemic medical condition (e.g. Down syndrome etc.)\n* Presence of an orofacial deformity\n* Presence of dental caries\n* Use of systemic antimicrobial therapy within 30 days of the baseline visit\n* Presence of any condition which, in the opinion of the investigator, makes participation in the project not in the individual's best interest.",true,"ALL","9 Months","15 Months",{"count":22,"type":23},70,"ESTIMATED","OBSERVATIONAL","The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of severe early childhood caries (S-ECC).",[27,28,29],"Candida Infection","Oral Thrush","Early Childhood Caries",[31,32,33,34,35],"Oral candidiasis","Candida infection","Oral thrush","Early childhood caries","Oral Health","RECRUITING","2026-06-18",{"date":39,"type":40},"2026-06-22","ACTUAL",{"date":42,"type":40},"2024-09-01",{"date":44,"type":23},"2028-08-31",{"name":46,"class":47},"Temple University","OTHER"]