[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oral":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100619426","oral-melatonin-versus-oral-pregabalin-on-postoperative-pain-and-anxiety-following-spine-surgery-100619426",false,"NCT07344467","Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery","Effect of Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery: A Prospective, Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 21-60 years old.\n* Both sexes.\n* Patients of American Society of Anesthesiologists (ASA) physical status I \\& II.\n* Undergoing elective spine surgery.\n\nExclusion Criteria:\n\n* Patient refusal.\n* History of allergic reactions to melatonin or pregabalin.\n* Patients with cardiovascular disease (ischemic heart disease, Heart Failure, Arrythmia, Heart Block).\n* Patients with kidney disease with (plasma creatinine level \\> 1.5mg\u002Fdl).\n* Patients with liver disease with (aspartate transaminase, alanine transaminase, and bilirubin levels more than twice the upper limit of normal).\n* Psychological and cognitive disorders; dementia; major depression.\n* Circadian rhythm disorders such as chronic fatigue syndrome and drowsiness.","ALL","21 Years","60 Years",{"count":20,"type":21},105,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the efficacy of using Melatonin versus Pregabalin on postoperative pain and anxiety after spine surgeries.",[27,28,29,30,31,32],"Oral","Melatonin","Pregabalin","Postoperative Pain","Anxiety","Spine Surgery","RECRUITING","2026-01-17",{"date":36,"type":37},"2026-01-21","ACTUAL",{"date":34,"type":37},{"date":40,"type":21},"2027-06-01",{"name":42,"class":43},"Tanta University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100601817","effectiveness-of-school-based-oral-health-intervention-for-children-100601817","NCT07115433","Effectiveness of School-based Oral Health Intervention for Children","Effectiveness of a School-Based Oral Health Promotion Program on Oral Health Practices, Behaviour, Self-Efficacy, and Clinical Outcomes Among Primary School Children: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Children aged 6-8 years enrolled in selected schools\n* Written informed consent from parents\u002Fguardians and assent from children\n\nExclusion Criteria:\n\n* Children with systemic conditions affecting oral health\n* Those currently in other oral health interventions",true,"6 Years","8 Years",{"count":56,"type":21},600,[24],"Schools provide an ideal setting for early interventions. Evidence suggests that educational programs incorporating behavioural change theories can improve oral hygiene practices and clinical outcomes.\n\nA School-Based Oral Health Promotion Program on Oral Health Practices, Behaviour, Self-Efficacy, and Clinical Outcomes Among Primary School Children for six months, while the control group will receive no intervention, only routine care.",[27,60],"Health","NOT_YET_RECRUITING","2025-08-03",{"date":64,"type":37},"2025-08-11",{"date":66,"type":21},"2025-08-05",{"date":68,"type":21},"2026-02-10",{"name":70,"class":43},"Universiti Putra Malaysia",3]