[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orogastric-tube\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orogastric-tube":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100574933","effects-of-intermittent-feeding-methods-with-nasogastric-and-orogastric-tubes-in-preterm-infants-100574933",false,"NCT06765720","Effects of Intermittent Feeding Methods With Nasogastric and Orogastric Tubes in Preterm Infants","The Comparison of the Effects of Intermittent Feeding Methods With Nasogastric and Orogastric Tubes on Growth, Nutrition, and Physiological Parameters in Preterm Infants: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Preterm infants with a gestational age of ≥30 weeks at birth, determined according to the mother's last menstrual period, and appropriate for gestational age,\n* Postmenstrual age of ≥30 weeks at the time of inclusion in the study,\n* Recommended for enteral feeding by a neonatologist,\n* Infants starting enteral feeding for the first time and fed at three-hour intervals using gravity-assisted nasogastric or orogastric tubes,\n* Infants who have not undergone oral feeding trials,\n* Infants who have not received any oral motor interventions,\n* Infants whose parents have given consent for inclusion in the study and signed an informed consent form after being provided with detailed information.\n\nExclusion Criteria:\n\n* Infants receiving mechanical ventilation support during the study,\n* Infants with an umbilical catheter,\n* Infants who received intubation, CPAP, or nasal prong oxygen support for more than 14 days before inclusion in the study,\n* Infants with craniofacial anomalies such as cleft palate, cleft lip, or facial muscle paralysis,\n* Infants with any gastrointestinal, neurological, or chromosomal disease (e.g., necrotizing enterocolitis, grade III and IV intracranial hemorrhage, periventricular leukomalacia, hydrocephalus, Down syndrome, and other diseases),\n* Infants with severe bronchopulmonary dysplasia according to the criteria of Jobe and Bancalari (2001) or requiring surgical treatment for patent ductus arteriosus.",true,"ALL","30 Weeks","36 Weeks",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","The study is a randomized controlled, prospective, double-blind trial planned to compare the effects of intermittent feeding methods using nasogastric and orogastric tubes on the growth, nutrition, and physiological parameters of preterm infants.\n\nThe population of the study will consist of preterm infants admitted to the Neonatal Intensive Care Unit of a public hospital in Istanbul between February and December 2025. The sample will include 60 preterm infants who meet the research criteria and whose parents agree to participate in the study.\n\nThrough randomization, preterm infants will be assigned to either the nasogastric tube group (experimental) or the orogastric tube group (control) from their first enteral feeding until the transition to full oral feeding is completed.\n\nData for preterm infants in both groups will be collected using the \"Preterm Infant Information Form, Early Feeding Skills Assessment Tool, and Nutrition Monitoring Form,\" which were developed by the researchers based on literature information and expert opinions. These data will encompass growth, nutrition, and physiological parameters before, during, and after feeding throughout the study.\n\nHypotheses of the Study\n\nH0: There is no significant difference in the effects of intermittent feeding methods using nasogastric and orogastric tubes on growth, feeding complications, and physiological parameters in preterm infants.\n\nH1: There is a significant difference between intermittent feeding methods using nasogastric and orogastric tubes in preterm infants in terms of growth parameters (daily weight gain in grams, time to regain birth weight, time to transition to full enteral feeding, time to transition to full oral feeding, and Early Feeding Skills Assessment Tool score).\n\nH1(1): Preterm infants fed with a nasogastric tube have greater daily weight gain (grams) compared to those fed with an orogastric tube.\n\nH1(2): The time to regain birth weight (days) in preterm infants fed with a nasogastric tube is shorter compared to those fed with an orogastric tube.\n\nH1(3): The time to transition to full enteral feeding (days) in preterm infants fed with a nasogastric tube is shorter compared to those fed with an orogastric tube.\n\nH1(4): The time to transition to full oral feeding (days) in preterm infants fed with a nasogastric tube is shorter compared to those fed with an orogastric tube.\n\nH1(5): The Early Feeding Skills Assessment Tool score of preterm infants fed with a nasogastric tube is higher compared to those fed with an orogastric tube.\n\nH2: There is a significant difference between intermittent feeding methods using nasogastric and orogastric tubes in preterm infants in terms of feeding complications (tube replacement, mucosal trauma, and feeding intolerance).\n\nH2(1): The frequency of tube replacement in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH2(2): The incidence of mucosal trauma in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH2(3): The incidence of feeding intolerance in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH3: There is a significant difference between intermittent feeding methods using nasogastric and orogastric tubes in preterm infants in terms of physiological parameters (oxygen saturation, heart rate, and apnea).\n\nH3(1): The oxygen saturation levels during and after feeding in preterm infants fed with a nasogastric tube are higher compared to those fed with an orogastric tube.\n\nH3(2): The heart rate during and after feeding in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH3(3): The incidence of apnea in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.",[28,29],"Nasogastric Tube","Orogastric Tube",[31,32,33,34,35],"intermittent feeding","enteral feeding","nasogastric tube","orogastric tube","preterm","NOT_YET_RECRUITING","2025-01-03",{"date":39,"type":40},"2025-01-09","ACTUAL",{"date":42,"type":22},"2025-02-01",{"date":44,"type":22},"2025-12-01",{"name":46,"class":47},"İstanbul Yeni Yüzyıl Üniversitesi","OTHER"]