[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oropharyngeal-leak-pressure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oropharyngeal-leak-pressure":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100628425","effects-of-continuous-monitoring-and-progressive-regulation-of-inflatable-laryngeal-mask-airway-cuff-pressure-on-postoperative-pharyngolaryngeal-complications-in-elderly-patients-100628425",false,"NCT07461467","Effects of Continuous Monitoring and Progressive Regulation of Inflatable Laryngeal Mask Airway Cuff Pressure on Postoperative Pharyngolaryngeal Complications in Elderly Patients","Inclusion Criteria:\n\n* Aged ≥ 60years;\n* Non-cardiac, non-thoracic, and non-head and neck surgery;\n* Non-laparoscopic surgery;\n* Elective surgery;\n* Surgical position: supine position ;\n* American Society of Anesthesiologists (ASA) physical status classification Ⅰ-Ⅲ;\n* New York Heart Association (NYHA) cardiac function classification Ⅰ-Ⅱ;\n* Expected surgical duration ≥30 minutes and ≤ 2 hours;\n* Body mass index (BMI) 18.5-30.0 kg\u002Fm2.\n\nExclusion Criteria:\n\n* Preoperative predictable difficult airways, such as trismus, limited neck mobility, and other related conditions;\n* Preoperative pharyngeal and laryngeal complications including sore throat, hoarseness, blood-tinged sputum, and dysphagia;\n* Preexisting conditions such as loose teeth, laryngeal obstruction, laryngeal edema, acute airway inflammation, and gastrointestinal bleeding;\n* Comorbidities of respiratory diseases like chronic obstructive pulmonary disease (COPD) and asthma;\n* Allergies to ILMA materials (e.g., silicone, polyvinylchloride \\[PVC\\]);\n* Inability to cooperate with the study for any reason;\n* Participation in other clinical trials within 3 months prior to enrollment in this study;\n* Any other circumstances deemed inappropriate for inclusion by the investigators.","ALL","60 Years",{"count":18,"type":19},146,"ESTIMATED","INTERVENTIONAL",[22],"NA","Currently, research on laryngeal mask airway (LMA) has been continuously deepened both domestically and internationally, which has greatly promoted the optimization process of clinical application and related management strategies. Numerous domestic and foreign research findings have consistently emphasized the key role of LMA cuff pressure monitoring in reducing postoperative complications, especially in alleviating sore throat and dysphagia. Foreign studies have extensively covered the research and development innovation of LMA devices, as well as comprehensive comparative analyses with other airway management methods such as endotracheal intubation, providing rich perspectives for expanding the application of LMA and improving its application effects. In contrast, domestic studies have distinct pertinence, focusing on application exploration in specific populations and clinical practice scenarios, and have provided important evidence for the safe and effective use of LMA in specific groups through in-depth research. However, it is undeniable that there are obvious deficiencies in both domestic and foreign research regarding the application of continuous monitoring and progressive regulation of LMA cuff pressure in elderly patients-a crucial field. Due to the natural decline of physiological functions, elderly patients face an increased risk of complications such as pulmonary and extrapulmonary complications, as well as pharyngolaryngeal complications, when using LMA during the perioperative period. Therefore, it is particularly urgent to carry out continuous pressure monitoring and progressive regulation of LMA cuff pressure, and to further explore the optimal range of LMA cuff pressure. This study will not only fill the current research gap but also provide solid support for the safe and efficient airway management of elderly patients during the perioperative period.",[25,26,27,28,29,30,31],"Elderly (People Aged 65 or More)","LMA","Randomized Controlled Trial","Laryngeal Mask Airways","Pharyngolaryngeal Postoperative Pain","Cuff Pressure","Oropharyngeal Leak Pressure",[33,34,35,36,27],"Elderly people","Laryngeal mask airways","pharyngolaryngeal complications","cuff pressure","RECRUITING","2026-03-06",{"date":40,"type":41},"2026-03-10","ACTUAL",{"date":43,"type":41},"2025-11-02",{"date":45,"type":19},"2027-03-01",{"name":47,"class":48},"First Affiliated Hospital of Chongqing Medical University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":15,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":20,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":49},"100576249","the-effects-of-gma-tulip-i-gel-and-blockbuster-laryngeal-mask-in-surgeries-with-lateral-position-under-general-anesthesia-100576249","NCT06782841","The Effects of GMA-TULIP, I-gel, and BlockBuster Laryngeal Mask in Surgeries With Lateral Position Under General Anesthesia","Inclusion Criteria:\n\n1. Patients received surgeries in lateral position with an estimated surgery duration of less than 3 hours under general anesthesia.\n2. Ages between 18 to 80, and body mass index less than 28 kg\u002Fm².\n3. American Society of Anesthesiologists (ASA) Grades I-III.\n4. Patients are willing to participate and be able to understand and sign an informed consent form.\n\nExclusion Criteria:\n\n1. Individuals with an open bite of less than 2cm.\n2. Individuals with a history of obvious regurgitation of gastric contents and risk factors for aspiration.\n3. Patients with combined pharyngeal and laryngeal lesions.\n4. Predicting difficult airway patients.\n5. Hearing, intellectual, communication, and cognitive impairments.\n6. Any reason that prevents cooperation with the study or that the researcher deems inappropriate for inclusion in this trial.","18 Years","80 Years",{"count":59,"type":19},102,[22],"To compare the efficacy and safety of traditional inflatable laryngeal mask, i-gel non-inflatable laryngeal mask and GMA-TULIP non-inflatable laryngeal mask in surgeries with lateral position under general anesthesia, so that providing evidence for the selection of laryngeal mask in surgeries with lateral position.",[31],"2025-01-14",{"date":65,"type":41},"2025-01-20",{"date":67,"type":41},"2024-08-21",{"date":69,"type":19},"2026-06-01",{"name":71,"class":48},"The Second Affiliated Hospital of Chongqing Medical University"]