[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oropharyngeal-neoplasms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oropharyngeal-neoplasms":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100565449","human-papillomavirus-association-and-genomic-exploration-in-head-neck-squamous-cell-carcinomas-100565449",false,"NCT06642324","Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas","Exploration of Human Papillomavirus Association and Genomic Characteristics in Head and Neck Squamous Cell Carcinomas in Bangladesh","HPV & HNSCC","Inclusion Criteria:\n\n1. Patient Age: adult (\\> 18 years)\n2. Head and neck squamous cell carcinoma diagnosed by biopsy (Histopathology confirmed HNSCC).\n3. Diagnosed cases specific Head-Neck sub-sites: (oral cavity, oropharynx, hypopharynx, larynx, tongue)\n4. Patient's Consent\n\nExclusion Criteria:\n\n1. Patient Age: children (\\\u003C 18 years)\n2. Cancers of any part of the body other than the head-neck region.\n3. People without HNSCC\n4. Any chronic diseases, genetic diseases, acute\u002Fchronic infectious diseases, etc. -",true,"ALL","18 Years",{"count":21,"type":22},550,"ESTIMATED","OBSERVATIONAL","Head and neck squamous cell carcinoma (HNSCC) represents a significant public health burden in Bangladesh with a high incidence and mortality rate. While traditional risk factors like tobacco and betel nut chewing contribute to HNSCC incidence, the emergence of HPV-associated HNSCC presents a unique challenge. The main goal of this observational study is to explore the prevalence, risk factors, and biological mechanisms underlying food habits and HPV-driven HNSCC in the population and identify the genomic changes and characteristics related to this malignancy. This study will provide the prevalence of HPV-associated HNSCC and screening the HPV typing in the Bangladeshi population, identify risk factors, and any biologically driven mechanisms causing HNSCC.",[26,27],"Head Neck Cancer","Oropharyngeal Neoplasms","RECRUITING","2024-12-28",{"date":31,"type":32},"2024-12-31","ACTUAL",{"date":34,"type":32},"2024-04-30",{"date":36,"type":22},"2025-09-30",{"name":38,"class":39},"Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh","OTHER"]