[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orthodontic-appliances\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orthodontic-appliances":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100609141","phase-3-orthodontic-pain-alleviation-with-chewing-gum-100609141",false,"NCT07210697","Orthodontic Pain Alleviation With Chewing Gum","Inclusion Criteria:\n\n* Participant and Parents able to sign and understand consent\n* Ability to chew gum\n\nExclusion Criteria:\n\n* Pregnant or Breastfeeding women","ALL","18 Years",{"count":18,"type":19},60,"ESTIMATED","INTERVENTIONAL",[22],"PHASE3","The aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience. The long-term goal is to enable clinicians to decide whether prescription of chewing gum at the placement of orthodontic appliances can improve patient experience with orthodontic treatment. In specific, a total of 60 patients under the age of 18 will be recruited for the study. Consent will be signed by both the child patient and the parents. 30 patients will be asked to chew xylitol gum and the other 30 patients will refrain from chewing gum and serve as the control group. At the appointment for insertion of orthodontic appliances, patients will be instructed to chew one serving or two pieces of xylitol gum three times per day for a total of six grams of xylitol per day. Patients will participate in a survey at the following timepoints- 4 hours, 24 hours, 48 hours and 7 days. The expectation is that this study will determine the effectiveness of using xylitol to decrease pain in orthodontic patients.",[25],"Orthodontic Appliances",[27,28],"Orthodontic Pain","xylitol gum","NOT_YET_RECRUITING","2025-09-29",{"date":32,"type":33},"2025-10-07","ACTUAL",{"date":35,"type":19},"2025-10",{"date":37,"type":19},"2026-03",{"name":39,"class":40},"West Virginia University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":4,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":41},"100602731","benefits-of-an-orthodontic-device-removable-functional-appliance-in-the-management-of-malocclusionsorofacial-dysfunctions-100602731","NCT07127328","Benefits of an Orthodontic Device Removable Functional Appliance in the Management of Malocclusions\u002FOrofacial Dysfunctions","Benefits of an Orthodontic Device (Removable Functional Appliance in the Management of Malocclusions\u002FOrofacial Dysfunctions","Inclusion Criteria:\n\n* Patients who had a malocclusion and\u002For a dysfunction which can be treated by removable functionnal appliance\n\nExclusion Criteria:\n\n* Patients who don't need a removable functionnal appliance.",true,{"count":51,"type":19},40,"OBSERVATIONAL","The removable functional appliance's goal is to restore functional balance (breathing, swallowing, chewing, etc.) and muscular balance (facial muscles, etc.) in the child. This promotes the establishment of a harmonious and stable occlusion.. The objective of this study is to investigate the benefits of an orthodontic device (removable functional appliance ) in the management of malocclusions\u002Forofacial dysfunctions",[25],"2025-08-11",{"date":57,"type":33},"2025-08-17",{"date":59,"type":19},"2025-09-01",{"date":61,"type":19},"2025-09-30",{"name":63,"class":40},"Centre Hospitalier Universitaire de Nice"]