[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orthodontic-retainers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orthodontic-retainers":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100600502","biological-reaction-of-direct-3d-printed-retainers-100600502",false,"NCT07098325","Biological Reaction of Direct 3d Printed Retainers","Evaluation of Biological Reaction of Direct Three Dimensional Printed Retainers","Inclusion Criteria:\n\n* -Finished fixed orthodontic therapy and seeking for retention as a part of their original treatment plan.\n* Good oral hygiene.\n* No habits (e.g., smoking)\n\nExclusion Criteria:\n\n* Medication affecting saliva.\n\n  * intrinsic tooth discoloration.\n  * Uncooperative patients.\n  * Patient with periodontitis.\n  * Learning difficulties and inability to read written instructions.","ALL",{"count":18,"type":19},26,"ESTIMATED","INTERVENTIONAL",[22],"NA","The aim of this study will be to evaluate the biological reaction of direct three dimensional printed retainers.\n\nPrimary objective is to evaluate bacterial growth and color stability between different thicknesses of 3d printed material used as a retainer .\n\nSecondary objective is to determine the optimal thickness for use in clear aligner fabrication based on biological performance.",[25],"Orthodontic Retainers",[27,28,29,30],"Different thicknesses","Direct three dimensional printed retainers","Bacterial growth","Color change","RECRUITING","2025-07-25",{"date":34,"type":35},"2025-08-01","ACTUAL",{"date":37,"type":19},"2025-10-01",{"date":39,"type":19},"2027-06-01",{"name":41,"class":42},"Al-Azhar University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":20,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100556783","comparison-between-cadcam-and-conventional-mandibular-fixed-retainers-100556783","NCT06529601","Comparison Between CAD\u002FCAM and Conventional Mandibular Fixed Retainers.","Comparison Between CAD\u002FCAM and Conventional Mandibular Fixed Retainers: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients who have completed fixed orthodontic therapy between the ages of 13 and 20 years;\n* Patients whose parents will sign the informed consent\n\nExclusion Criteria:\n\n* Presence of dental anomalies in number (excess or deficiency) in the lower anterior teeth\n* Patients with metal allergies.","13 Years","20 Years",{"count":54,"type":19},54,[22],"The devices compared in this study are 'retainers', i.e. fixed orthodontic retainers applied to the lingual surface of the central and lateral incisors and lower canines bilaterally. Their function is to maintain dental alignment once fixed orthodontic therapy has ended. In particular, the CAD\u002FCAM device Keeppy patented by the company Leone SpA (Via Ponte a Quaracchi 50, Sesto Fiorentino, Florence) will be compared with the standard retainer made from a steel braided wire (Ortho FlexTech, Reliance Orthodontic Products Inc., 1540 West Thorndale Ave, Itasca, Illinois, USA).\n\nThis is a single-center, national, controlled, superiority, randomized, crossover, open-label study.\n\nThe aim of this study is to evaluate whether the CAD\u002FCAM retainer results in fewer failures (fractures or detachments) over a period of 6 months and 2 years compared to the standard retainer. In addition, the aim of the study is to evaluate whether the Keeppy device results in the maintenance of better periodontal health as judged by the use of plaque and bleeding indices on the surfaces of the lower six anterior teeth compared to the standard retainer. Other objectives consist of the patient's assessment of pain, difficulty in speaking and esthetic satisfaction and the stability of the lower anterior tooth sector.",[25],"NOT_YET_RECRUITING","2024-07-29",{"date":61,"type":35},"2024-07-31",{"date":63,"type":19},"2024-09-01",{"date":65,"type":19},"2027-09-01",{"name":67,"class":42},"Azienda Ospedaliero-Universitaria Careggi"]