[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orthodontic-treatment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orthodontic-treatment":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,48,83,111,137,165,196,222,247],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":32,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100588957","exploration-of-the-utility-of-dental-dedicated-mri-for-dentistry-100588957",false,"NCT06948162","Exploration of the Utility of Dental-dedicated MRI for Dentistry","Inclusion Criteria:\n\n1. Patient Age: 18 years old or older\n2. Receiving imaging for routine dental care\n3. Does not have a serious medical condition\n4. Is not pregnant or is not potentially pregnant\n5. Is willing and able to give consent in English\n6. Has the ability to manage their own calendar and schedule appointments\n7. Willing to have a separate 2-hour appointment to have an MRI\n\nExclusion Criteria:\n\n1. Unable to consent to participant in English\n2. Serious health condition, which includes but not limited to renal failure\u002Fon dialysis, unstable heart disease (uncontrolled arrhythmia, cardiomyopathy and\u002For unable to lay flat, within 1 month of cardiac catheterization or myocardial infarction), unstable cerebral vascular disease (within 1 month of stroke and\u002For stent placement), diabetes (type I or II) not controlled by medication or diet, uncontrolled seizures, uncontrolled hyperthyroidism, non-allergic bronchospasm (chronic obstructive pulmonary disease and emphysema), uncontrolled movement disorder, and liver failure\n3. Pregnant and\u002For intending to become pregnant,\n4. Prisoner and\u002For not able to manage their own scheduling\n5. Screen positive on MR safety questionnaire, specifically including people that have worked with or otherwise been exposure to metal particles and have the potential for such particles to be embed within them.",true,"ALL","18 Years",{"count":19,"type":20},300,"ESTIMATED","OBSERVATIONAL","This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images. The standard clinical dental images consist of radiographs, such as bitewings, periapical, panoramic, cone-beam CT, and medical CT, as well medical MRIs of the temporomandibular joints (TMJ).The conceptualization of research questions, study designing, and interpretation of imaging data has and will involve content expertise in all ddMRI research.",[24,25,26,27,28,29,30,31],"Dental Crowding","Dental Occlusion, Traumatic","Dental Pain","TMD\u002FOrofacial Pain","TMD","Orthodontics","Endodontic Disease","Orthodontic Treatment",[33,34],"Diagnosis","Magnetic resounance imaging","RECRUITING","2026-05-18",{"date":38,"type":39},"2026-05-20","ACTUAL",{"date":41,"type":39},"2025-03-14",{"date":43,"type":20},"2027-12-31",{"name":45,"class":46},"University of Minnesota","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":15,"sex":16,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":47},"100633850","comparison-of-three-orthodontic-separators-for-pain-plaque-and-tooth-separation-100633850","NCT07532044","Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation","Separation Effect, Plaque Score, Pain Perception, And Impact On Quality Of Life When Comparing Three Types Of Orthodontic Separators: A Randomized Controlled Trial","SEP-ORTHO","Inclusion Criteria:\n\n* Patients requiring fixed orthodontic appliance therapy with maxillary first molar banding\n* Age between 12 and 25 years\n* Good oral hygiene (Plaque Index score 0-1)\n* Good general oral health\n* No previous orthodontic treatment\n* No history of dental extractions\n* Presence of tight interproximal contacts at the site of separator placement (no spacing)\n\nExclusion Criteria:\n\n* Presence of interproximal restorations\n* Presence of interproximal caries\n* Missing maxillary second premolar, first molar, or second molar\n* Unerupted maxillary second molars\n* Systemic diseases affecting oral health (e.g., diabetes mellitus)\n* Regular use of medications affecting pain perception (e.g., analgesics, corticosteroids)\n* Loss of separators before follow-up appointment\n* Failure to return within 72 hours for evaluation","12 Years","25 Years",{"count":59,"type":20},144,"INTERVENTIONAL",[62],"NA","Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily activities.\n\nThis study aims to compare three commonly used types of orthodontic separators-elastomeric, Kesling, and customized tie wire separators-in terms of the amount of tooth separation achieved, pain experienced by patients, and plaque accumulation.\n\nIn addition, the study will assess how these separators affect patients' quality of life, including eating, speaking, and daily comfort.\n\nParticipants will be assigned to one of the three separator types and will be evaluated after 48 to 72 hours. The findings of this study may help identify the most effective and comfortable separator, improving patient care and treatment experience in orthodontics.",[65,66,31],"Orthodontic Pain (D013850)","Malocclusion",[68,69,70,71,72],"Orthodontic separators","Pain perception","Plaque index","Quality of life","Tooth separation","NOT_YET_RECRUITING","2026-05-05",{"date":76,"type":39},"2026-05-08",{"date":78,"type":20},"2026-04-10",{"date":80,"type":20},"2028-04-10",{"name":82,"class":46},"Islamabad Medical and Dental College",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":60,"phases":92,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":47},"100628986","effect-of-individually-trained-oral-prophylaxis-itop-on-gingival-health-in-orthodontic-patients-100628986","NCT07468773","Effect of Individually Trained Oral Prophylaxis (iTOP) on Gingival Health in Orthodontic Patients","Effect of Individually Trained Oral Prophylaxis (iTOP) Versus Conventional Oral Hygiene Instruction on Gingival Health in Orthodontic Patients Using Calibrated Interdental Brushes: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Adults aged 18 years or older\n2. Patients undergoing fixed orthodontic treatment\n3. Diagnosis of biofilm-induced gingivitis\n4. Presence of interdental spaces suitable for calibrated interdental brush use\n5. Ability and willingness to perform oral hygiene procedures and attend follow-up visits\n6. Provision of written informed consent\n\nExclusion Criteria:\n\n1. Presence of systemic diseases affecting gingival health (e.g., uncontrolled diabetes)\n2. Use of medications known to influence gingival conditions (e.g., phenytoin, cyclosporine, calcium channel blockers)\n3. History of chemotherapy or radiotherapy in the head and neck region\n4. Current smokers\n5. Pregnant or lactating women\n6. Patients with physical or cognitive disabilities affecting oral hygiene performance\n7. Use of additional professional oral hygiene interventions or antimicrobial mouth rinses during the study period",{"count":91,"type":20},60,[62],"This randomized controlled clinical trial aims to evaluate the effectiveness of individualized oral hygiene education using the Individually Trained Oral Prophylaxis (iTOP) method compared with conventional oral hygiene instruction using model demonstration and video-based education in orthodontic patients diagnosed with gingivitis.\n\nSixty orthodontic patients underwent professional mechanical plaque removal and received oral hygiene instruction using calibrated interdental brushes. Participants were randomly assigned to either the iTOP training group or the conventional education group.\n\nClinical outcomes including Approximal Plaque Index (API), Gingival Index (GI), and Full Mouth Bleeding Score (FMBS) were assessed at baseline and after three months to determine the effectiveness of the educational interventions on plaque control and gingival health.",[95,31],"Gingivitis",[97,98,99,100,101],"Interdental Brushes","iTOP","Oral Hygiene Education","Approximal Plaque Index","Plaque Control","2026-03-09",{"date":104,"type":39},"2026-03-13",{"date":106,"type":20},"2026-03-30",{"date":108,"type":20},"2026-09-30",{"name":110,"class":46},"Gulf Medical University",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":47},"100627201","gingival-recessions-in-orthodontically-treated-and-untreated-adult-patients-100627201","NCT07445555","Gingival Recessions in Orthodontically Treated and Untreated Adult Patients","Gingival Recessions in Orthodontically Treated and Untreated Adult Patients: a Prospective Study","Inclusion Criteria:\n\n* Patients with or without previous history of orthodontic treatment with and without gingival recessions\n* ≥ 18 years old\n* American Society of Anesthesiologists Classification I or II\n\nExclusion criteria:\n\n* Patients with history of periodontal disease\n* taking the following medication: anticoagulants, phenytoin, cyclosporine, nifedipine or calcium channel blockers\n* Patients with prior history of radio or chemotherapy\n* Pregnant or breastfeeding patients\n* Patients with agenesis of one or more lower incisors\n\nExclusion Criteria:\n\nPatients with history of periodontal disease Patients taking the following medication: anticoagulants, phenytoin, cyclosporine, nifedipine or calcium channel blockers Patients with prior history of radio or chemotherapy Pregnant or breastfeeding patients Patients with agenesis of one or more lower incisors",{"count":119,"type":20},50,"To identify the predisposing parameters for gingival recessions in adult patients seeking orthodontic treatment. The ultimate aim is to provide a clinical guideline to estimate the risk of developing post-orthodontic gingival recessions.",[122,31],"Gingival Recession",[124,125,126,127],"gingival recession","orthodontic treatment","gingival phenotype","occlusal factors","2026-03-02",{"date":130,"type":39},"2026-03-03",{"date":132,"type":39},"2023-11-15",{"date":134,"type":20},"2027-09-01",{"name":136,"class":46},"Universitaire Ziekenhuizen KU Leuven",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":60,"phases":146,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":47},"100623533","salivary-flow-ph-and-buffering-capacity-in-fixed-and-clear-aligner-orthodontic-treatment-100623533","NCT07397871","Salivary Flow, pH, and Buffering Capacity in Fixed and Clear Aligner Orthodontic Treatment","Changes in Salivary Parameters in Patients Undergoing Clear Aligner Orthodontic Treatment: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Class I, II and III skeletal malocclusion.\n* Age ≥18 undergoing fixed or Clear aligner orthodontic treatment.\n\nExclusion Criteria:\n\n* Current medications including antibiotic use within the past 3 months that affect salivary flow and composition.\n* Active smoking including vaping and E-cigarette use.\n* Diagnosis of systemic diseases\u002Fconditions such as Sjogren's syndrome, diabetes, chronic kidney diseases, neurological conditions.\n* Active dental caries or signs of gingivitis and\u002For periodontitis\n* Less than three months of orthodontic treatment since it is characterized by acute, temporary changes and patient adaptation to the new appliances.\n* Requiring single arch treatment to standardize the research and eliminate a potential confounding variable\n* Crown restoration is excluded due to their material properties which may affect salivary composition.\n* Pregnancy due to the physiological variation in salivary flow and composition due to hormonal changes.\n* Presence of mouth breathing may lead to inconsistent salivary flow rate, Changes in Salivary Composition and pH\n* Poor oral hygiene with high levels of dental plaque, calculus, and gingival inflammation can independently alter salivary flow rate, pH, and buffer capacity there by acting as confounding variable.",{"count":145,"type":20},40,[62],"Study Design: A randomized controlled trial with two parallel arms and an allocation ratio of 1:1.\n\nSetting: The study will be conducted in the orthodontic department of Riyadh Elm University hospitals in Riyadh City, Saudi Arabia.\n\nParticipants: Patients undergoing fixed or clear aligner orthodontic treatment referred to REU dental hospital will be randomly allocated to either the clear aligner group or the fixed orthodontic appliance group.\n\nIntervention: Prior to orthodontic treatment, all patients will receive phase I periodontal therapy and oral hygiene instructions. Fixed orthodontic appliances will be bonded using metallic brackets with a 0.022-inch slot and 0.014-inch NiTi archwires. Clear aligner patients will receive Invisalign® treatment.\n\nOutcomes and Saliva Collection: Salivary samples will be collected using the spitting method at baseline (T0) and follow-up time points according to the study protocol. Salivary flow rate, pH, and buffering capacity will be assessed as described in the proposal.\n\nRandomization and Blinding: Randomization will be performed using a random number generator with allocation concealment via opaque envelopes. The investigators involved in outcome assessment and data analysis will be blinded.\n\nEthical Considerations: The study will be submitted to the Institutional Review Board at Riyadh Elm University and conducted in accordance with IRB policies.",[31,149],"Saliva",[151,152,153,154,155],"Salivary flow","Salivary pH","Buffering capacity","Fixed orthodontic appliance","Clear aligner therapy","2026-02-02",{"date":158,"type":39},"2026-02-09",{"date":160,"type":20},"2026-03-15",{"date":162,"type":20},"2027-05-29",{"name":164,"class":46},"Riyadh Elm University",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":15,"sex":16,"minAge":171,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":60,"phases":175,"briefSummary":176,"conditions":177,"keywords":181,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":189,"startDateStruct":191,"completionDateStruct":192,"leadSponsor":194,"locationsCount":47},"100599971","a-split-mouth-clinical-trial-evaluating-the-bond-failure-rate-of-a-new-etch-free-orthodontic-adhesive-100599971","NCT07091422","A Split-Mouth Clinical Trial Evaluating the Bond Failure Rate of a New Etch-Free Orthodontic Adhesive","Inclusion Criteria:\n\nPatients aged 14 to 35 years\n\nRequiring comprehensive fixed orthodontic treatment with brackets on both arches\n\nGood general health with no contraindications to orthodontic treatment\n\nPresence of at least 10 permanent teeth per arch suitable for bracket bonding\n\nAbility and willingness to comply with study visits and follow-up for at least 12 months\n\nParent\u002Fguardian consent and child assent obtained as appropriate\n\nExclusion Criteria:\n\nPresence of systemic diseases or conditions that affect oral health or healing (e.g., uncontrolled diabetes, immunosuppression)\n\nTeeth with significant enamel defects, restorations, or caries in bonding areas\n\nPatients currently undergoing or who have undergone orthodontic treatment previously\n\nHistory of allergy or sensitivity to dental adhesives or related materials\n\nPatients with poor oral hygiene or active periodontal disease\n\nUse of medications known to affect tooth enamel or oral tissues (e.g., long-term corticosteroids)\n\nInability to attend follow-up visits or anticipated lack of compliance\n\nParticipation in another clinical trial that could interfere with study outcomes","14 Years","35 Years",{"count":174,"type":20},20,[62],"This randomized, split-mouth clinical trial will evaluate a new orthodontic adhesive that eliminates the need for acid etching before bracket bonding. Conventional orthodontic bonding requires etching enamel with phosphoric acid, which can weaken the outer enamel layer and increase the risk of white spot lesions and enamel damage. The etch-free adhesive under investigation is designed to simplify the bonding procedure while preserving enamel integrity.\n\nTwenty orthodontic patients starting treatment with braces will participate. For each patient, one side of the mouth (left or right) will be randomly assigned to receive the etch-free adhesive, while the opposite side will receive the conventional adhesive with acid etching. This intra-patient design allows a direct comparison under identical oral conditions.\n\nParticipants will be followed for 12 months. Bracket failures, bonding time, ease of adhesive removal, enamel surface condition after debonding, and the presence of white spot lesions will be recorded. If effective, the etch-free adhesive may reduce enamel damage without compromising bond strength, providing a safer and more efficient bonding option for orthodontic patients.",[178,31,179,180],"Bracket Bonding","Dental Adhesives\u002FRestorations Performance","White Spot Lesion of Tooth",[182,183,184,185,186,187],"Etch-Free Adhesive","Orthodontic Bonding","Bracket Failure","Split-Mouth Trial","White Spot Lesions","Orthodontics Clinical Trial","2025-11-05",{"date":190,"type":39},"2025-11-10",{"date":188,"type":39},{"date":193,"type":20},"2026-12-01",{"name":195,"class":46},"University of Maryland, Baltimore",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":15,"sex":16,"minAge":56,"maxAge":17,"enrollmentInfo":203,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":205,"conditions":206,"keywords":208,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":47},"100609682","impact-of-increased-body-mass-index-on-adolescent-fixed-orthodontic-treatment-a-prospective-longitudinal-study-100609682","NCT07217756","Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study","Influence of Body Mass Index on Gingival Health, White Spot Lesions, Whole Salivary Proinflammatory Cytokine and Adipokine Profile and Candida and Streptococcus Mutans Carriage Among Adolescents Undergoing Fixed Orthodontic Therapy","Inclusion Criteria:\n\n* adolescents (12-17 years old);\n* patients scheduled to undergo comprehensive fixed orthodontic therapy (OT) (for at least 6 months with metal braces\u002Fwires) on both dental arches;\n* patients with increased BMI (≥25.0 Kg\u002Fm2) (test-Group);\n* patients with normal BMI \\[18.5-24.99 (Kg\u002Fm2)\\] (control-Group);\n* patients with all 6 mandibular anterior teeth present and mild-to-moderate mandibular crowding (\\\u003C7.5 mm);\n* patients and parents\u002Fguardians willing to provide signed assent\u002Fpermission.\n\nExclusion Criteria:\n\n* self-reported habitual tobacco product users;\n* patients with self-reported medical diseases such as hepatic diseases, blood disorders, cardiovascular diseases, HIV, diabetes mellitus, and viral infections;\n* patients with craniofacial syndromes and\u002For cleft lip and palate;\n* pregnant and\u002For lactating females (by self\u002Fparent report);\n* edentulous individuals;\n* patients with active or a history of periodontitis;\n* patients having undergone surgical and\u002For non-surgical periodontal therapy within the past 6 months;\n* patients with physical and\u002For mental\u002Fcognitive disabilities who are decisionally-impaired and not able to consent\u002Fassent for themselves;\n* patients who reported use of medications such as antibiotics, steroids (inhalers and\u002For pills), non-steroidal anti-inflammatory drugs, and antimicrobial mouth-rinses within the past 3 months or those who require prophylactic antibiotics prior to dental procedures;\n* patients undergoing cancer therapy;\n* underweight patients (BMI less than 18.5 Kg\u002Fm2);\n* patients with oral mucosal lesions such as median rhomboid glossitis and lichen planus;\n* patients with clinically visible carious teeth.",{"count":204,"type":20},52,"The goal of this prospective observational study is to assess the influence of increased body mass index (BMI) on various oral health and orthodontic-related parameters in adolescents undergoing orthodontic therapy (OT) with braces. These parameters include gum inflammation, tooth decalcifications\u002Fdiscolorations, tooth alignment of lower incisors, and various inflammatory and microbiological parameters in the collected saliva and gum fluid of the patients. The primary purpose is to assess if an increased BMI is a risk factor for oral inflammation in adolescents undergoing OT. The main questions it aims to answer are:\n\n1. Do patients with an increased BMI undergoing OT demonstrate increased microbial counts in the saliva compared to patients with normal BMI?\n2. Do patients with increased BMI undergoing OT demonstrate increased gum inflammation, tooth discolorations, and higher levels of inflammatory markers in the saliva and gum fluid samples compared to patients with normal BMI? This study will include 2 study groups (patients with increased BMI-test group, and normal weight patients-control group). The participants will be asked to complete a study questionnaire, which will collect information regarding their demographics, their family socioeconomic and educational status, dietary habits, and oral health-related quality of life. The participants will also receive an oral examination (evaluation of their gum health), and they will have their intraoral photos taken, as well as an impression of their lower teeth (to create dental models). A saliva sample will be obtained by asking patients to passively \"drool\" in a tube, and a gingival fluid sample will be collected from the gums of the lower anterior teeth using thin paper strips. All these study procedures will be conducted at baseline (T1: before bonding of braces), and at an approximately 6-month follow-up visit (T2). Comparisons of these outcomes will be conducted between the two groups and across timepoints.",[207,31],"Obesity & Overweight",[209,210,125,211,212],"body mass index","obesity","adolescents","fixed orthodontic appliances","2025-10-15",{"date":215,"type":39},"2025-10-20",{"date":217,"type":39},"2022-04-22",{"date":219,"type":20},"2026-11-01",{"name":221,"class":46},"University of Rochester",{"id":223,"slug":224,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":15,"sex":16,"minAge":229,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":60,"phases":233,"briefSummary":234,"conditions":235,"keywords":236,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":47},"100601177","comparison-of-periodontal-health-bonding-time-and-failure-between-direct-and-indirect-fixed-retainer-placement-among-orthodontic-patients-100601177","NCT07107100","Comparison of Periodontal Health, Bonding Time and Failure Between Direct and Indirect Fixed Retainer Placement Among Orthodontic Patients","Comparison of Periodontal Health, Bonding Time and Failure Between Direct and Indirect Fixed Retainer Placement Among Orthodontic Patients - A Modified Split-mouth Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged between 18 - 40 years\n* Patients who read, write and understand English language\n* Patients undergoing fixed orthodontic treatment\n* Patients with good oral hygiene, with grade 1 or below on plaque and gingival indices at the time of debonding of brackets.\n* All patients who will sign the informed consent form\n\nExclusion Criteria:\n\n* Patients with periodontal disease\n* Patients with any systemic disease\n* Pregnant or nursing females\n* Patients who cannot come for follow up appointments for a retainer check up","13 Years","40 Years",{"count":232,"type":20},30,[62],"The placement technique of retainers in both maxillary and mandibular arches can influence the time taken for bonding the retainer in the mouth of a patient which can in turn affect the patient´s response to the procedure. The different placement techniques can influence the stability of the retainer wire on teeth and the maintenance of periodontal health during the retention period. Therefore, it is essential to know which technique is better suited for placement and its influence on periodontal health so that in the future it helps clinicians save their time during placement of retainers while benefiting the patients. To our knowledge, this will be the first study both locally and internationally that will include an assessment of periodontal health, time duration of placement and stability of fixed retainer in the maxillary arch as well. Three months period is sufficient for assessment of periodontal health and failure of retainer, long term studies can be at a risk of attrition bias.\n\nOBJECTIVES:\n\nThe objectives of this study are:\n\n* The primary objective of this study is to compare the failure of fixed retainers, along with periodontal health and bonding time, which are bonded either through direct method or indirect method on patients undergoing orthodontic debonding through a modified split-mouth technique using mean values for plaque index, gingival index, calculus index follow up appointments over a period of three months.\n* The secondary objective of the study is to assess the amount of time taken during placement of retainers via both direct and indirect bonding of fixed retainers",[31],[237],"fixed retainer, retainer breakage","2025-07-30",{"date":240,"type":39},"2025-08-06",{"date":242,"type":39},"2024-01-01",{"date":244,"type":20},"2025-08-21",{"name":246,"class":46},"Aga Khan University Hospital, Pakistan",{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":251,"acronym":252,"eligibilityCriteria":253,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":254,"targetDuration":4,"studyType":60,"phases":255,"briefSummary":256,"conditions":257,"keywords":260,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":47},"100582081","effectiveness-of-auxiliary-segmental-lingual-appliances-in-leveling-the-curve-of-wilson-at-second-molars-100582081","NCT06858670","Effectiveness of Auxiliary Segmental Lingual Appliances in Leveling the Curve of Wilson at Second Molars","EASLALCW","Inclusion Criteria:\n\n* Patients undergoing labial fixed orthodontic treatment.\n* Patients exhibiting an excessive (deep) Curve of Wilson at the second molar bilaterally (meaning lingually inclined mandibular second molar).\n* Patients willing to participate and provide informed consent.\n\nExclusion Criteria:\n\n* Patients with limited mouth opening and gagging reflex preventing placement of auxiliary segmental lingual appliances.",{"count":174,"type":20},[62],"This study aims to evaluate the effectiveness of auxiliary segmental lingual appliances in leveling the Curve of Wilson at the second molars in patients undergoing labial fixed orthodontic treatment. Patients exhibiting an excessive (deep) Curve of Wilson at the second molar bilaterally (meaning lingually inclined mandibular second molar) will be recruited.. Using a split-mouth design, one side will receive the intervention (auxiliary segmental lingual appliances), while the other side will serve as the control. The variables measured include the Curve of Wilson at the second and first molars, and the distance from the mesiolingual and distolingual cusps of the second molar to the occlusal plane of the first molar. Measurements will be taken on digital impressions at baseline (T0), after leveling with a stainless steel labial archwire (T1), and three months after applying the auxiliary segmental lingual appliances. The effectiveness will be assessed by comparing the two groups.",[66,258,259,31],"Malocclusion; Displaced or Missing Teeth","Malocclusions",[261,262,263,264,265,266,66,267,268],"Auxiliary Segmental Lingual Appliances","Curve of Wilson","Second Molars","Labial Fixed Orthodontic Treatment","Split-Mouth Design","Digital Impressions","Dental Occlusion","Orthodontic Treatment Outcomes","2025-02-27",{"date":271,"type":39},"2025-03-05",{"date":273,"type":20},"2025-03-01",{"date":275,"type":20},"2029-03-01",{"name":277,"class":46},"Hanoi Medical University"]