[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orthognathic-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orthognathic-surgery":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,45,76,103,125,150,170,199,223,242,270],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100643168","tooth-and-bone-borne-cuttingrepositioning-guide-and-patient-specific-implantpsi-100643168",false,"NCT07634276","Tooth and Bone-borne Cutting\u002FRepositioning Guide and Patient-specific Implant(PSI)","A Prospective, Randomized, Controlled, Single-blind Study on the Hybrid Tooth and Bone-supported Cutting and Repositioning Guides Versus Computer-aided Design\u002FComputer-aided Manufactured Splints in \"Surgery-first\" Orthognathic Surgery","PSI","Inclusion Criteria:\n\n1. Age ranged from 18 to 40 years old.\n2. Patients were diagnosed with dentofacial deformity and received treatment at the Plastic Surgery Hospital, Chinese Academy of Medical Sciences. The diagnosis was confirmed via comprehensive evaluation by two senior attending plastic surgeons.\n3. Patients were scheduled for bimaxillary orthognathic surgery, with optional adjunctive procedures including maxillary and mandibular subapical osteotomy and genioplasty.\n4. Patients were indicated for the surgery-first approach based on joint assessment by craniomaxillofacial surgeons and orthodontists. Orthodontists confirmed that satisfactory occlusal relationships could be achieved through postoperative orthodontic treatment. Preoperative dental conditions met the following requirements: no or mild anterior dental crowding, flat or shallow Spee's curve, slight incisor inclination, harmonious maxillary and mandibular dental arches, and at least three stable occlusal contacts under transitional occlusion.\n5. Patients agreed to complete follow-up examinations and provided signed informed consent.\n\nExclusion Criteria:\n\n1. Patients who refused to participate in the present study.\n2. Presence of comorbidities that may increase surgical risks or impair surgical outcomes, as assessed by two senior plastic surgeons, including but not limited to hypertension, diabetes, immune thrombocytopenic purpura, and hemoglobin (Hb) level ≤ 100 g\u002FL.\n3. Presence of body dysmorphic disorder, a history of psychiatric disorders, or excessively demanding patients with unrealistic treatment expectations.\n4. Presence of facial skeletal tumors.\n5. Patients who required revision surgery after previous orthognathic procedures.\n6. Cases judged unable to achieve stable occlusal relationships through postoperative orthodontic treatment following joint evaluation by craniomaxillofacial surgeons and orthodontists, including patients with severe dental crowding, maxillomandibular arch width discrepancy, temporomandibular joint disorders, or periodontal diseases.",true,"ALL","18 Years","40 Years",{"count":22,"type":23},50,"ESTIMATED","INTERVENTIONAL",[26],"NA","Dentofacial deformity refers to a group of disorders characterized by malocclusion and facial asymmetry resulting from developmental abnormalities of the maxilla and mandible, which cause morphological and positional anomalies of the jaws. Compared with the traditional orthodontics-orthognathic surgery-orthodontics treatment protocol, the surgery-first approach has witnessed a continuous expansion of its clinical application scope. Nevertheless, academic controversies persist regarding its indication boundaries, postoperative jaw stability, and adaptive changes of the temporomandibular joint.\n\nIn orthognathic surgery, computer-aided design\u002Fcomputer-aided manufacturing (CAD\u002FCAM) surgical guides indirectly determine the three-dimensional spatial positions of the maxilla and mandible through occlusal relationships. The tooth-bone dual-supported osteotomy and positioning guide combined with pre-bent patient-specific implants (PSIs) forms a novel surgical guide system that enables independent and direct positioning of the maxilla. Theoretically, this system can eliminate errors derived from mandibular positional instability and thereby improve surgical accuracy. However, comparative studies investigating the clinical application of these two types of guides in surgery-first orthognathic surgery are still lacking.\n\nThis prospective, randomized, controlled, single-blind clinical study aimed to explore the clinical value of PSIs and conventional CAD\u002FCAM guides in surgery-first orthognathic surgery, with primary outcomes focusing on surgical accuracy, postoperative jaw stability, and temporomandibular joint alterations. The findings will provide evidence-based medical support for the expanded application of this novel technique in precision orthognathic surgery.",[29,30,31,32],"CAD\u002FCAM","Patient Specific Implant","Orthognathic Surgery","Surgery-first","NOT_YET_RECRUITING","2026-06-03",{"date":36,"type":37},"2026-06-08","ACTUAL",{"date":36,"type":23},{"date":40,"type":23},"2028-12-31",{"name":42,"class":43},"Peking Union Medical College","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":18,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":24,"phases":56,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":44},"100636866","phase-4-impact-of-preemptive-analgesia-on-postoperative-pain-in-orthognathic-surgery-100636866","NCT07571252","Impact of Preemptive Analgesia on Postoperative Pain in Orthognathic Surgery","Impact of Preemptive Analgesia on Postoperative Pain in Patients Undergoing Orthognathic Surgery: A Randomized Controlled Trial.","Inclusion Criteria:\n\n* Adults aged 21 to 65 years.\n* American Society of Anesthesiologists (ASA) physical status I or II.\n* Scheduled to undergo orthognathic surgery including bilateral sagittal split osteotomy and Le Fort I osteotomy under general anesthesia.\n* Ability to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding.\n* Known allergy or intolerance to acetaminophen, ibuprofen, or other nonsteroidal anti-inflammatory drugs (NSAIDs).\n* Renal dysfunction, defined as estimated glomerular filtration rate \\\u003C60 mL\u002Fmin\u002F1.73 m².\n* Hepatic dysfunction, defined as liver enzyme levels greater than twice the upper limit of normal.\n* History of bleeding disorders or coagulopathy.\n* Active or recent peptic ulcer disease.\n* Current use of recreational drugs, including cannabis, that in the judgment of the investigators could interfere with anesthesia management, postoperative pain assessment, or study outcomes.\n* Any medical condition that, in the judgment of the investigators, would make participation unsafe or interfere with study participation.","21 Years","65 Years",{"count":55,"type":23},72,[57],"PHASE4","This randomized controlled clinical trial evaluates the effect of preemptive analgesia on postoperative pain outcomes in adult patients undergoing orthognathic surgery. Participants scheduled for bilateral sagittal split osteotomy and Le Fort I osteotomy under general anesthesia will be randomized to one of three groups: intravenous acetaminophen, intravenous ibuprofen, or a control group receiving standard postoperative analgesia without preoperative medication.\n\nThe study aims to determine whether the administration of pre-surgical analgesics reduces postoperative pain intensity and analgesic requirements during the early postoperative period. Pain will be assessed using a standardized pain scale at multiple time points following surgery, and secondary outcomes will include postoperative analgesic consumption and patient satisfaction with pain control.\n\nThis investigation seeks to contribute evidence supporting multimodal analgesic strategies and improved postoperative pain management in patients undergoing orthognathic surgery.",[60,31],"Post Operative Pain",[62,31,63,64,65,66],"Preemptive Analgesia","Postoperative Pain","Maxillofacial Surgery","Multimodal Analgesia","Randomized controlled trial","2026-04-29",{"date":69,"type":37},"2026-05-06",{"date":71,"type":23},"2026-04",{"date":73,"type":23},"2027-02",{"name":75,"class":43},"University of Puerto Rico",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":83,"targetDuration":4,"studyType":24,"phases":85,"briefSummary":86,"conditions":87,"keywords":88,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100625134","accuracy-of-maxillary-two-customized-3d-titanium-miniplates-versus-four-customized-3d-miniplates-100625134","NCT07418684","Accuracy of Maxillary Two Customized 3D Titanium Miniplates Versus Four Customized 3D Miniplates","Accuracy of Maxillary Two Customized 3D Titanium Miniplates Versus Four Customized 3D Miniplates for Virtual Plan Transfer in Orthognathic Surgery. Randomized Clinical Trial.","Inclusion Criteria:\n\n.Patients with dentofacial disharmony and misalignment requiring orthognathic surgeries.\n\n* Patients with no signs or symptoms of active TMDs.\n* Highly motivated patients.\n\nExclusion Criteria:\n\n* Patients who refused to be included in the research.\n* Patients with systemic diseases that may hinder the normal healing process or render the patient not fitting for general anesthesia.\n* Patients with intra-bony lesions or infections that may retard the osteotomy healing.",{"count":84,"type":23},10,[26],"In this research the investigators aim to minimize the use of more hardware in the fixation of the orthognathic surgery cases. The objective of this study is to assess the accuracy of the plan transfer with two customized titanium plates versus four customized titanium plates.",[31],[89,90,91],"virtual surgical planning","Le fort 1","PSSO","RECRUITING","2026-02-14",{"date":95,"type":37},"2026-02-18",{"date":97,"type":37},"2025-03-01",{"date":99,"type":23},"2026-12-01",{"name":101,"class":43},"Cairo University",2,{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":24,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":44},"100619904","effect-of-orthognathic-surgery-on-plantar-pressure-and-posture-100619904","NCT07350681","Effect of Orthognathic Surgery on Plantar Pressure and Posture","Evaluation of the Effects of Orthognathic Surgery on Plantar Pressure Distribution and Posture","Inclusion Criteria:\n\n* Study Group (Orthognathic Surgery Group)\n\nParticipants will be eligible for inclusion in the surgical cohort if they meet all of the following criteria:\n\nIndividuals scheduled to undergo single-jaw or double-jaw orthognathic surgery as part of comprehensive orthodontic treatment.\n\nCurrently receiving orthodontic therapy utilizing clear aligner systems or fixed orthodontic appliances.\n\nAvailability of preoperative lateral cephalometric radiographs obtained as part of routine clinical evaluation.\n\nAge ≥ 18 years at the time of enrollment.\n\nCompletion of a minimum of 6 months of postoperative orthodontic treatment, enabling standardized follow-up evaluation.\n\nBody Mass Index (BMI) \\\u003C 30 kg\u002Fm², to minimize confounding effects related to obesity on postural and plantar pressure measurements.\n\nControl Group (Non-surgical Group)\n\nParticipants will be eligible for inclusion in the control cohort if they meet all of the following criteria:\n\nIndividuals not undergoing orthognathic surgery during the study period.\n\nReceiving orthodontic treatment with clear aligners or fixed appliances, comparable to the surgical cohort.\n\nBMI \\\u003C 30 kg\u002Fm².\n\nAge ≥ 18 years.\n\nNo participation in physical activities or rehabilitative programs that may alter postural parameters or plantar pressure distribution during the study period.\n\nExclusion Criteria:\n\n* Participants from either cohort will be excluded if they exhibit:\n\nNeuromuscular, musculoskeletal, or postural disorders that may independently influence balance or plantar pressure distribution.\n\nHistory of previous orthognathic or maxillofacial surgery.\n\nSystemic diseases affecting bone metabolism, neuromuscular function, or gait.\n\nPregnancy.\n\nInability or unwillingness to comply with study procedures or follow-up assessments.",{"count":111,"type":23},60,[26],"Orthognathic surgery leads to changes in the three-dimensional position of the jaws, which may result in alterations in head and neck posture as well as overall body posture. These postural changes are also expected to influence plantar pressure distribution. This study aims to evaluate the direction and magnitude of these changes by assessing posture and plantar pressure measurements before and after orthognathic surgery.\n\nPostural analysis and plantar pressure measurements will be performed preoperatively and at the 6-month postoperative follow-up in patients undergoing orthognathic surgery. In order to allow a reliable comparison, a control group consisting of non-operated individuals will also be included. The range of natural changes observed in the control group will be determined, and the outcomes will be compared between the surgical and control groups.\n\nBy comparing preoperative and postoperative measurements, this study aims to evaluate the effects of orthognathic surgery on body posture and plantar pressure distribution. The findings are expected to contribute to the identification of parameters that should be considered in postoperative evaluation and rehabilitation. Furthermore, the results will provide valuable information regarding the postural and plantar pressure changes observed in patients following orthognathic surgery.",[31,115],"Postural Balance","2026-01-11",{"date":118,"type":37},"2026-01-20",{"date":120,"type":37},"2025-09-29",{"date":122,"type":23},"2026-05",{"name":124,"class":43},"Ayşenur Dindar",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":4,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":24,"phases":134,"briefSummary":135,"conditions":136,"keywords":137,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":4},"100616912","accuracy-of-maxillary-fixation-using-custom-plates-on-nasal-buttress-only-via-minimally-invasive-approach-versus-custom-plates-on-nasal-and-zygomatic-buttresses-via-conventional-approach-in-orthognathic-surgeries-100616912","NCT07311785","Accuracy of Maxillary Fixation Using Custom Plates on Nasal Buttress Only Via Minimally Invasive Approach Versus Custom Plates on Nasal and Zygomatic Buttresses Via Conventional Approach in Orthognathic Surgeries","Accuracy of Maxillary Fixation Using Custom Plates on Nasal Buttress Only Via Minimally Invasive Approach Versus Custom Plates on Nasal and Zygomatic Buttresses Via Conventional Approach in Orthognathic Surgeries: A Randomized Controlled Trial.","Inclusion Criteria:\n\n* Patients with dentofacial disharmony and misalignment requiring bimaxillary orthognathic surgeries.\n* Patients with no signs or symptoms of active TMDs.\n* Highly motivated patients.\n\nExclusion Criteria:\n\n* Patients who refused to be included in the research.\n* Patients with systemic diseases that may hinder the normal healing process or render the patient not fitting for general anaesthesia.\n* Patients with intra-bony lesions or infections that may retard the osteotomy healing.",{"count":133,"type":23},30,[26],"The goal of this clinical trial is to evaluate of the accuracy maxilla fixation using custom plates on nasal buttress only via minimally invasive approach versus using custom plates on nasal and zygomatic buttresses via conventional approach. The main question it aims to answer is:\n\n• Is the minimally invasive approach accurate and stable ? Researchers will compare minimally invasive technique to the traditional technique of fixation of the maxilla bone to see if it is as accurate and stable.\n\nParticipants will:\n\n* Undergo surgey\n* Follow up visits weekly for a month then on a monthly basis for 5 more months.",[31],[138,139,140,141],"orthognathic","minimally invasive","nasal buttress","custom plate","2025-12-16",{"date":144,"type":37},"2025-12-31",{"date":146,"type":23},"2025-12",{"date":148,"type":23},"2026-06",{"name":101,"class":43},{"id":151,"slug":152,"hasResults":11,"nctId":153,"briefTitle":154,"officialTitle":154,"acronym":155,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":24,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":44},"100579271","simulation-of-facial-soft-tissue-in-orthognathic-surgery-100579271","NCT06822127","Simulation of Facial Soft Tissue in Orthognathic Surgery","SPOC","Inclusion Criteria:\n\n* Patient over 18 ;\n* Patients who have been informed of the study and who have freely given their informed consent to participate in the study;\n* Patient undergoing isolated mandibular or maxillary orthognathic surgery, or maxillo-mandibular surgery with or without genioplasty for any indication (occlusal disorder, sleep apnoea syndrome, functional joint disorder, etc.);\n* Patient covered by a French social security scheme\n\nExclusion Criteria:\n\n* Patient with maxillary disjunction ;\n* Patients with facial malformations;\n* Pregnant or breast-feeding patient;\n* Patient under guardianship;\n* Patients who do not understand French;\n* Patients under court protection\n* No pre- or postoperative CT scan or CT scan that cannot be used\n* Surgery, trauma, progressive infection or cosmetic injection on the face after orthognathic surgery and before the postoperative scan",{"count":133,"type":23},[26],"Orthognathic surgery consists of rebalancing the position of the jaws, taking into account functional criteria (tooth engagement, tooth\u002Flip ratio, breathing, etc.) and aesthetic criteria. It has become much more accurate in recent years thanks to the advent of osteosynthesis plates and the contribution of three-dimensional imaging. Three-dimensional imaging makes it possible to simulate fairly accurately the surgical procedures and bone displacements required. However, the effect of these bone displacements on the soft tissues (skin, subcutaneous tissue, muscles) does not make it possible, with today's digital tools, to simulate the final aesthetic result and in particular to anticipate the sometimes significant postoperative changes to the face. Many patients are worried about these post-operative morphological changes and would like to have a precise idea of how they will look after surgery. Being able to offer them, before surgery, a visual solution simulating the final aesthetic appearance would be essential in this respect.\n\nThe aim of the study is to validate the predictions provided by the digital face model on a series of patients scheduled for orthognathic surgery by comparing the simulation of the morphological result of the operation, provided by our algorithm (SPOC), with the actual result assessed on a scan taken 6 months after the operation.",[31],"2025-11-14",{"date":163,"type":37},"2025-11-17",{"date":165,"type":37},"2025-04-28",{"date":167,"type":23},"2027-10-31",{"name":169,"class":43},"Centre Hospitalier Annecy Genevois",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":177,"enrollmentInfo":178,"targetDuration":4,"studyType":24,"phases":180,"briefSummary":181,"conditions":182,"keywords":185,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":44},"100593451","hilotherapy-vs-kinesio-taping-in-orthognathic-surgery-recovery-100593451","NCT07006610","Hilotherapy vs. Kinesio Taping in Orthognathic Surgery Recovery","Comparison of the Effects of Hilotherapy and Kinesio Taping on Edema, Pain, and Trismus After Orthognathic Surgery","Inclusion Criteria:\n\n* Patients scheduled to undergo bimaxillary orthognathic surgery (Le Fort I + BSSRO)\n* Age between 18 and 50 years\n* No systemic disease\n* Voluntary participation with signed informed consent\n\nExclusion Criteria:\n\n* Presence of systemic disease or immunosuppressive medication\n* Known allergy to kinesio tape\n* Inability to attend follow-up appointments\n* Facial anatomical deformities preventing measurement","50 Years",{"count":179,"type":23},36,[26],"This prospective randomized controlled trial aims to compare the effects of kinesio taping and hilotherapy on postoperative edema, pain, and trismus in patients undergoing bimaxillary orthognathic surgery.",[183,63,184,31],"Postoperative Edema","Trismus",[186,187,31,188,189],"Hilotherapy","Kinesio Taping","Postoperative Complications","Postoperative Recovery","2025-05-27",{"date":192,"type":37},"2025-06-05",{"date":194,"type":37},"2024-09-15",{"date":196,"type":23},"2025-07-15",{"name":198,"class":43},"Medipol University",{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":203,"acronym":4,"eligibilityCriteria":204,"healthyVolunteers":11,"sex":18,"minAge":205,"maxAge":20,"enrollmentInfo":206,"targetDuration":4,"studyType":24,"phases":208,"briefSummary":209,"conditions":210,"keywords":213,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":221,"locationsCount":4},"100581583","time-and-type-dependent-evaluation-of-different-techniques-for-correction-of-cleft-maxillary-hypoplasia-100581583","NCT06852196","Time and Type Dependent Evaluation of Different Techniques for Correction of Cleft Maxillary Hypoplasia","Inclusion Criteria:\n\n* Cleft patients either cleft alveolus or cleft alveolus and palate.\n* Surgically fit patients.\n* Patients ready for orthognathic assessment undergoing either surgical or orthodontics correction.\n\nExclusion Criteria:\n\n* Non- cleft cases .\n* Previous correction.\n* History of active infection or underlying disease such as hematologic disorders neoplasm, and immune deficiency.\n* Patient refused to sign an informed consent.","12 Years",{"count":207,"type":23},22,[26],"Maxillary hypoplasia in CLP deformities results from congenital reduction in midfacial growth and the effects of the surgical scar from CLP repair.Turvey et al. suggested that this disproportionate jaw growth is the biologic consequence of prior surgical intervention for closure of the soft tissues and is not related to the congenital cleft deformity, Midfacial hypoplasia is commonly treated by performing conventional Le Fort surgery to displace the maxilla anteriorly and stabilization afterward with rigid fixation along with orthodontics treatment. .\n\nMidface hypoplasia cleft patient has the following characteristics: concave facial profile, inverted nasal tip, wide alar base, acute nasolabial angle, and excessive exposure of sclera. Intraoral findings are anterior and posterior crossbite, CLP, accentuated curve of Spee, Class III dental malocclusion, multiple missing teeth, oronasal communication, and residual cleft. Speech disturbances are also usually present due to velopharyngeal incompetency and oronasal communication.",[211,212,31],"Maxillary Hypoplasia","Cleft Lip Palate",[214],"cleft maxillary hypoplasia","2025-02-26",{"date":217,"type":37},"2025-02-28",{"date":219,"type":23},"2025-02-21",{"date":99,"type":23},{"name":222,"class":43},"Assiut University",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":229,"targetDuration":4,"studyType":230,"phases":4,"briefSummary":231,"conditions":232,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":240,"locationsCount":44},"100571015","soft-tissue-prediction-in-orthognathic-surgery-by-making-anatomically-accurate-virtual-model-100571015","NCT06714747","Soft Tissue Prediction in Orthognathic Surgery by Making Anatomically Accurate Virtual Model","Inclusion Criteria:\n\n* Patients undergoing orthognathic surgery and preoperative radiographic study with CBCT and MRI\n* Patients with age \\> or = 18 years old\n* Obtaining informed consent\n* Patients with preoperative teleradiography and orthopantomography\n\nExclusion Criteria:\n\n* patients with cleft lip-palate, facial malformations and\u002For syndromes (syndromes with involvement of the cephalic extremity, such as sd of Apert. Cropuzon, Ofeiffer, Treacher Collins)\n* patients who have undergone application of Medpor prostheses or who have undergone ancillary procedures (lipofilling, fillers, volumetric facial augmentations with insertion of polyethylene ketone prostheses)",{"count":84,"type":23},"OBSERVATIONAL","The role of orthognathic surgery in the correction of dento-skeletal dysmorphies, whether they are Class II or Class III or asymmetries, is to improve both the function and aesthetic appearance of thepatient. Both aspects are equally important to achieve optimal results.\n\nWhen the surgeon plans the surgery, he or she must therefore take into account the effects that bone displacements will have at the level of the soft tissues directly involved in the surgery, such as the maxilla and mandible. Traditionally, such surgery consists of an orthodontic presurgical phase1,2\n\n.",[31],"2024-12-02",{"date":235,"type":37},"2024-12-04",{"date":237,"type":37},"2022-01-11",{"date":239,"type":23},"2026-11-11",{"name":241,"class":43},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":248,"eligibilityCriteria":249,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":250,"targetDuration":4,"studyType":24,"phases":251,"briefSummary":252,"conditions":253,"keywords":257,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":44},"100554101","quantitative-evaluation-of-attention-to-faces-after-orthognathic-surgery-with-eye-tracking-100554101","NCT06494709","Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking","Pilot Study of Quantitative Evaluation of Attention to Faces of Patients With Orthognathic Surgery Using Eye-tracking","OCHIRO","Inclusion Criteria:\n\n* Naïve subject with regard to dentofacial deformities and their management\n* Subject with no known facial pathology\n* Subject having provided an informed consent\n* Subject \\> 18 years old\n\nExclusion Criteria:\n\n* Subject familiar with dentofacial deformities and their management (e.g., health professionals in the relevant specialties)\n* Subject with known facial pathology (dentofacial deformity or other)\n* Subject under guardianship, curators or justice protection",{"count":111,"type":23},[26],"Dentofacial deformities refer to morphological anomalies of the jaws. Their development during growth determines the shape of the lower third of the face and the type of dental occlusion. A maxillo-mandibular dysmorphosis associates morphological modification of the face and anomaly of the occlusion. If these anomalies are most often hereditary, they also depend on acquired factors such as swallowing, breathing, sucking or phonation disorders. Angle's classification defines three classes of dental occlusion: class I, when the ratio between the maxillary and mandibular first molars is normal, class II when the upper molar is too far forward, and class III when it is too far back. Class II and III dysmorphoses can result in an alteration of the masticatory function, pain (TMJ, headaches) or sleep apnea. At the same time, they cause patients to experience a decrease in self-esteem, anxiety and social discomfort. Class II and II usually require orthodontic treatment and orthognathic surgery to correctly align the jaws. This surgery has a positive impact on the dental occlusion and the functions concerned, but also on the facial morphology, all of which often leads to an improvement in the patient's quality of life.\n\nStandardized photographs presenting control subjects (class I) and patients (class II and class III) before and after surgery will be included in an approximately 10 min video sequence. Naive participants will look at this sequence during which the faces of the controls and the patients - before and after surgery - will alternate, with the instruction being free visual exploration of the images. The total fixation durations in defined areas of interest (eyes, nose, mouth, chin) will be recorded with an eye tracking device and the results will be processed using a dedicated software.",[254,31,255,256],"Dentofacial Deformities","Social Perception","Eye Tracking",[254,258,259,260],"orthognathic surgery","social perception","eye tracking","2024-07-10",{"date":263,"type":37},"2024-07-11",{"date":265,"type":37},"2024-07-02",{"date":267,"type":23},"2026-08",{"name":269,"class":43},"Centre Hospitalier Universitaire, Amiens",{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":277,"enrollmentInfo":278,"targetDuration":4,"studyType":24,"phases":280,"briefSummary":281,"conditions":282,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":287,"startDateStruct":289,"completionDateStruct":291,"leadSponsor":293,"locationsCount":44},"100542139","fracture-pattern-following-bilateral-sagittal-split-osteotomy-with-or-without-impacted-third-molars-100542139","NCT06338982","Fracture Pattern Following Bilateral Sagittal Split Osteotomy With or Without Impacted Third Molars","Fracture Pattern Following Bilateral Sagittal Split Osteotomy With or Without Impacted Third A Randomized Controlled Trial Assessing Fracture Pattern, Condylar Segment Positioning, Complications and Patient-reported Outcome Measures","Inclusion Criteria:\n\n* Patients scheduled for surgical correction of facial deformities involving BSSO or bimaxillary surgery with bilateral asymptomatic impacted mandibular third molars\n* Age between 18 and 75 years\n\nExclusion Criteria:\n\n* Fully erupted and well-functioning mandibular third molar\n* Unilateral impacted mandibular third molar\n* Pathology associated with the impacted mandibular third molar\n* BSSO combined with genioplasty\n* Previous mandibular fractures\n* Present neurosensory disturbances of the inferior alveolar nerve\n* Systemic bone disease or arthritis\n* Physical status classification system, ASA Class III or IV, specified patients with severe systemic disease ore patients with severe systemic disease that is constant threat to life\n* Failure to attend the entire observation period","75 Years",{"count":279,"type":23},150,[26],"The goal of this clinical trial is to investigate the hypothesis that there are none difference in the treatment result of orthognathic surgery on the lower jaw, with interoperative wisdom tooth removal rather than preoperative wisdom tooth removal. In patients with severe dental malocclusion combined with a dentofacial deformity. The main question it aims to answer are:\n\n• Is there a difference in the degree of complication and the patient's perception, with inter-operative wisdom tooth removal rather than pre-operative wisdom tooth removal.\n\nParticipants will be will be divided into two groups, with one group having their wisdom teeth removed 6 months before their jaw moving surgery and the other group having their wisdom teeth removed in connection with their jaw moving surgery.",[283,284,31,285],"Impacted Third Molar Tooth","Osteotomy","Mandibular Fractures","2024-03-24",{"date":288,"type":37},"2024-04-01",{"date":290,"type":23},"2024-03-30",{"date":292,"type":23},"2030-10-31",{"name":294,"class":43},"Kimie Bols Østergaard"]