[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orthotic-devices\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orthotic-devices":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100544013","the-effect-of-a-muscle-mimicking-fabric-type-shoulder-orthosis-on-functional-movements-of-the-upper-limb-in-patients-with-neuromuscular-disorder-100544013",false,"NCT06363357","The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder","Inclusion Criteria\n\n1. Patients with a confirmed diagnosis of a neuromuscular disease (NMD) by genetic testing, muscle biopsy, or electrodiagnostic studies, presenting with prominent upper limb muscle weakness. Examples include:\n\n   1. Muscular Dystrophies: Duchenne\u002FBecker Muscular Dystrophy (DMD\u002FBMD), Limb-Girdle Muscular Dystrophy (LGMD), Facioscapulohumeral Muscular Dystrophy (FSHD), etc.\n   2. Motor Neuron Diseases: Spinal Muscular Atrophy (SMA, Types 2 and 3), Amyotrophic Lateral Sclerosis (ALS, upper limb-dominant), etc.\n   3. Peripheral Neuropathies: Charcot-Marie-Tooth (CMT) disease, etc.\n   4. Other Neuromuscular Conditions: Including but not limited to cervical spinal cord injury.\n2. Aged over 10 years.\n3. A score of 2 to 5 on the Brooke Upper Extremity Functional Rating Scale.\n4. Manual Muscle Test (MMT) grade of less than 3 for shoulder abduction.\n5. Ability to provide written informed consent from the participant and\u002For their legal representative, indicating willingness to participate in the study.\n\nExclusion Criteria\n\n1. Unwillingness or inability to provide informed consent.\n2. A score of 1 or 6 on the Brooke Upper Extremity Functional Rating Scale.\n3. Cognitive impairment severe enough to interfere with the proper use of a shoulder orthosis.\n4. Any other condition which, in the opinion of the investigator, would make study participation inappropriate or unsafe for the patient.","ALL","10 Years",{"count":18,"type":19},30,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this clinical trial is to investigate the effect of a muscle-mimicking, fabric-type shoulder orthosis on functional movements of the upper limb in patients with neuromuscular disorder.\n\nThe main questions it aims to answer are:\n\n* What is the impact of the muscle-mimicking, fabric-type shoulder orthosis on upper limb functional movements in patients with neuromuscular disorder?\n* Are there observable differences in upper limb function when the shoulder orthosis is worn versus when it is not?\n\nParticipants will:\n\n* Receive education on how to wear and use the shoulder orthosis.\n* Undergo evaluations, including assessment of upper limb performance, shoulder muscle strength testing, active range of motion measurements, assessment of functional workspace, goal attainment scale evaluation, surface electromyography, physiological measurements such as blood pressure and heart rate, fatigue assessment, and assessment for any musculoskeletal or skin-related issues.\n\nResearchers will compare neuromuscular disorder patients before and while wearing and operating the shoulder orthosis to see if there are any significant effects on variables such as upper limb function, range of motion, functional workspace, goal attainment scale, and surface electromyography.",[25,26,27,28,29,30,31,32,33],"Muscular Dystrophy, Duchenne","Orthotic Devices","Upper Extremity","Neuromuscular Diseases (NMD)","Fascioscapulohumeral Muscular Dystrophy","Spinal Muscular Atrophy (SMA)","ALS (Amyotrophic Lateral Sclerosis)","LGMD","SCI - Spinal Cord Injury","RECRUITING","2025-11-25",{"date":37,"type":38},"2025-12-03","ACTUAL",{"date":40,"type":38},"2024-04-20",{"date":42,"type":19},"2025-12-31",{"name":44,"class":45},"Seoul National University Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":20,"phases":59,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100536641","boutonniere-deformity-effectiveness-of-thermoplastic-and-fabricated-orthoses-100536641","NCT06267469","Boutonniere Deformity Effectiveness of Thermoplastic and Fabricated Orthoses","Inclusion Criteria:\n\n* diagnosed with RA\n* diagnosed thumb deformity: butonier finger, type I or II\n* female\n* age 18 - 65 years\n* patient's consent to the study\n\nExclusion Criteria:\n\n* other deformity of the thumb\n* less than 1 year since surgical intervention in the hand\n* less than 6 months since delivery injections within the thumb\n* change in treatment during the study and 3 months before the study",true,"FEMALE","18 Years","65 Years",{"count":58,"type":19},60,[22],"The goal of this study is to present the author's thumb orthosis with a butonier deformity and its effect on hand function, strength, dexterity and pain levels in relation to patients wearing factory-made orthopedic supplies. It is planned to include about 60 people in the study (30 people each in the group with thermoplastic orthoses and 30 participants with factory-made orthoses)\n\nThe main questions it aims to answer are:\n\n1\\. How much improvement in dexterity will the patient wearing the orthosis get? 2. By how much will the grip strength of the whole hand and pincer grip strength improve with the orthosis? 3. How will wearing the orthosis affect the pain associated with the disease? Participants will\n\n1. measurement of grip strength of the right and left hands with a dynamometer in an orthosis and without an orthosis, at the time of the test conducted and at the appointed times.\n2. measurement of pincer grip strength with a dynamometer in an orthosis and without an orthosis, at the time of the test conducted and at the designated times.\n\n4\\. completion of the DASH questionnaire 6. assessment of the NRS pain scale in relation to the period of 6 months before the start of the study 7. Likert scale - evaluation of satisfaction with the use of the orthosis 8. the Kapandji scale Researchers will compare patients with thermoplastic orthosis and patients with fabric orthosis to see which is more functional.",[26],[63,64],"Boutonniere deformity","thermoplastic orthosis","2025-08-26",{"date":67,"type":38},"2025-09-03",{"date":69,"type":38},"2024-07-06",{"date":71,"type":19},"2026-09-30",{"name":73,"class":45},"Magdalena Kolasińska",2,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":15,"minAge":56,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":20,"phases":83,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":46},"100545864","feasibility-of-fabric-orthosis-for-knee-support-in-elderly-gait-improvement-100545864","NCT06387459","Feasibility of Fabric Orthosis for Knee Support in Elderly Gait Improvement","Safety and Feasibility of Knee Extensor Muscle-mimicking, Fabric-type Orthosis on Gait in Geriatric Patients: Pilot Clinical Trial","Inclusion Criteria:\n\nEligibility for participation in the study requires that all the following criteria are met:\n\n1. Age: Participants must be 65 years of age or older.\n2. Comprehension and Compliance: Able to fully understand and comply with the instructions and study procedures.\n3. Mobility-Impacting Conditions: Must have at least one of the following conditions affecting mobility: (1)Sarcopenia:\n\n   * Muscle Strength: Handgrip strength of \\\u003C28 kg for men and \\\u003C18 kg for women.\n   * Muscle Function: Short Physical Performance Battery (SPPB) score of 8 or less.\n   * Muscle Mass: Bioelectrical impedance analysis (BIA) showing muscle mass \\\u003C7.0 kg\u002Fm² for men and \\\u003C5.7 kg\u002Fm² for women. (2)Diabetes:\n   * Diagnosed distal symmetric polyneuropathy.\n   * Sensory impairments in toes or feet. (3)Knee Osteoarthritis:\n   * Kellgren-Lawrence grade ≥2.\n   * Persistent pain (≥3 months) with a severity of at least 3 on the Numerical Rating Scale (NRS).\n\nExclusion Criteria:\n\nIndividuals meeting any of the following criteria will be excluded from study participation:\n\n1. Inability to Consent: Unable to provide informed consent or not willing to participate in the study procedures.\n2. Severe Sensory or Motion Limitations: Including severe visual or vestibular impairments that could increase the risk of falling.\n3. Communication Barriers: Significant hearing, speech, or language problems that would hinder communication with study personnel.\n4. Independent Walking Inability: Cannot walk independently without the aid of a walking device.\n5. Other Significant Diseases or Conditions:\n\n   * Neurological disorders that affect walking ability (e.g., stroke, Parkinson's disease).\n   * Orthopedic or musculoskeletal conditions severely affecting lower limb function.\n   * Severe cardiovascular conditions including uncontrolled hypertension or heart failure.\n   * Respiratory diseases requiring regular oxygen therapy.\n   * Active cancer treatment or cancer treatment within the past 3 years (except basal cell carcinoma or localized prostate cancer).\n   * Severe psychiatric disorders like schizophrenia or bipolar disorder.\n6. Other Exclusionary Factors:\n\n   * Past severe orthopedic surgeries on lower limbs which might affect gait and mobility.\n   * Severe back pain or any other condition affecting mobility not already listed.",{"count":18,"type":19},[22],"This pilot clinical trial assesses the safety and feasibility of a novel fabric-type orthosis designed to mimic the knee extensor muscles and improve gait in elderly patients with mobility impairments due to conditions like sarcopenia, diabetes, or knee osteoarthritis. The study aims to test this orthosis in a real- world setting to see if it can enhance mobility and stability for elderly individuals, potentially reducing falls and improving quality of life. A total of 30 participants aged 65 and older will be recruited to use this orthosis across multiple sessions, where their gait will be analyzed under various conditions to measure the device's impact on walking speed, stability, and muscle activation.",[86,87,26],"Gait","Fall",[89],"Geriatric patient","2025-06-08",{"date":92,"type":38},"2025-06-11",{"date":94,"type":38},"2024-07-31",{"date":96,"type":19},"2026-05-14",{"name":44,"class":45}]