[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"orthotopic-liver-transplantation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:orthotopic-liver-transplantation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100576252","fecal-microbiota-transplantation-for-the-prevention-of-infectious-complications-after-liver-transplantation-100576252",false,"NCT06782880","Fecal Microbiota Transplantation for the Prevention of Infectious Complications After Liver Transplantation","Efficacy and Safety of Fecal Microbiota Transplantation for the Prevention of Early-onset Infectious Complications After Orthotopic Liver Transplantation","Inclusion Criteria:\n\n* Adult (age≥18 years) patients listed for OLT for various etiologies.\n* Patient's consent to participate in the study\n\nExclusion Criteria:\n\n* Previous total colectomy\n* Pregnancy or breastfeeding\n* Patients on oral or intravenous antimicrobial agents\n* HIV positive and not well controlled on antiretroviral therapy, or CD4+ \\\u003C200\u002F mm3\n* Active SARS-CoV-2 infection\n* Neutropenia \\\u003C0.5X10\\^9\u002FL\n* Toxic megacolon\n* Contraindications to colonoscopy\n* Any conditions for which, according to the physician, FMT endangers the patient's health\n* History of hypersensitivity to macrogol contained in bowel preparations.",true,"ALL","18 Years",{"count":20,"type":21},144,"ESTIMATED","INTERVENTIONAL",[24],"NA","The increasing emergence and spread of MDRB represents a major public health problem, with higher mortality in patients experiencing infections. Cirrhotic patients listed for OLT and after OLT are at high risk of MDRB colonization or infection due to the large use of broad-spectrum antibiotics in the post-transplant setting. Therefore, effective decolonization strategies in this particular setting are urgently needed. The investigators hypothesize that heterologous FMT can reduce infections rates in the pre-and post- OLT setting by MDRB decolonization and restoration of a more physiological microbiome.",[27,28,29],"Fecal Microbiota Transplantation","Orthotopic Liver Transplantation","Multi-drug Resistant Bacteria","RECRUITING","2025-01-14",{"date":33,"type":34},"2025-01-20","ACTUAL",{"date":36,"type":34},"2023-05-01",{"date":38,"type":21},"2026-05-31",{"name":40,"class":41},"IRCCS Azienda Ospedaliero-Universitaria di Bologna","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":4,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":42},"100573723","risk-and-protective-factors-for-relapse-to-alcohol-use-in-patients-with-liver-disease-undergoing-liver-transplantation-100573723","NCT06749990","Risk and Protective Factors for Relapse to Alcohol Use in Patients With Liver Disease Undergoing Liver Transplantation","Risk and Protective Factors for Relapse to Alcohol Use in Patients With Alcohol-related Liver Disease and Undergoing Orthotopic Liver Transplantation","Inclusion Criteria:\n\n* Patients who have signed the informed consent\n* Candidates for liver transplantation due to liver disease with alcohol-related etiology (either mono- or multifactorial)\n* For the retrospective part: patients who underwent OLT for ARLD during the time frame 2017-2022\n\nExclusion Criteria:\n\n* Major psychopathologies and active psychoses",{"count":51,"type":21},320,"OBSERVATIONAL","This is an observational, monocentric study, consisting of both a retrospective and a prospective component. The aim of the study is to identify risk and protective factors for alcohol relapse in patients with alcohol-related liver disease (ARLD) who have undergone orthotopic liver transplantation (OLT).",[55,28],"Alcohol Related Liver Disease","2024-12-19",{"date":58,"type":34},"2024-12-27",{"date":60,"type":34},"2024-01-09",{"date":62,"type":21},"2030-12-31",{"name":40,"class":41}]