[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"osgood-schlatter-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:osgood-schlatter-disease":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,52,79,108],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100633022","individualized-rehabilitation-for-osgood-schlatter-or-sever-pain-in-youth-athletes-100633022",false,"NCT07521280","Individualized Rehabilitation for Osgood-Schlatter or Sever Pain in Youth Athletes","Feasibility, Clinical Response, and Exploratory Predictors of an Individualized Load-Based Rehabilitation Pathway in Youth Athletes With Osgood-Schlatter Disease or Sever Disease: A Prospective Single-Arm Interventional Study","LEAP-REHAB","Inclusion Criteria:\n\n* Aged 10 to 17 years\n* Participates in organized sport and has at least 12 months of sport participation or training history\n* Has current lower-extremity apophyseal pain consistent with Osgood-Schlatter-related knee pain and\u002For Sever-related heel pain, or has previous Osgood-Schlatter-related or Sever-related symptoms with a residual or low-irritability presentation relevant to rehabilitation\n* Meets criteria for at least one pre-specified rehabilitation entry pathway:\n\npost-trial rehabilitation entry after completion of the separate photobiomodulation trial, or direct-entry rehabilitation with active apophyseal symptoms, or direct-entry rehabilitation with previous Osgood-Schlatter-related or Sever-related symptoms and a low-irritability or residual presentation\n\nFor participants entering with active symptoms:\n\n* pain is located at the tibial tubercle region and\u002For the calcaneal apophyseal\u002Fheel region\n* pain is aggravated by activity, loading, or sport participation\n* pain is reproducible on clinical examination or the clinical history is consistent with the target condition\n\nParticipant and parent\u002Fcaregiver are willing to take part in the rehabilitation program, including in-person visits, home exercises, symptom\u002Factivity monitoring, and follow-up assessments.\n\nA parent or legal guardian provides written informed consent, and the participant provides assent when applicable.\n\nExclusion Criteria:\n\n* Current pain episode started after an acute traumatic injury that better explains the symptoms\n* Clinical presentation suggests a condition other than the target rehabilitation condition, including a major alternative knee or heel diagnosis requiring different management\n* Lower-limb surgery that would substantially affect rehabilitation planning, safety, or interpretation of outcomes\n* Known serious musculoskeletal, neurological, rheumatological, inflammatory, autoimmune, metabolic, or other systemic disease that may affect safe participation or interpretation of outcomes\n* Any medical or developmental condition that would prevent safe participation in exercise-based rehabilitation\n* Current symptoms requiring urgent medical assessment or management outside the rehabilitation pathway\n* Inability to understand study instructions or complete study procedures with parent\u002Fcaregiver support\n* Parent\u002Fcaregiver or participant does not agree to participate or withdraws consent\u002Fassent","ALL","10 Years","17 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if a 12-week individualized rehabilitation program is feasible and helpful for children and adolescents with lower-extremity apophyseal pain, including Osgood-Schlatter-related knee pain and Sever-related heel pain. It will also learn about how well participants follow the program, whether the program can be delivered as planned, and whether pain, function, and sports participation improve during rehabilitation.\n\nThe main questions it aims to answer are:\n\n1. Can this rehabilitation program be delivered with good attendance, good home-exercise adherence, and complete follow-up data?\n2. Do pain, function, and sports participation improve during the rehabilitation period?\n3. Which baseline clinical, functional, ultrasound, maturity, or biomarker features may help explain who responds better to rehabilitation?\n\nAll participants will receive the same overall rehabilitation framework. The program includes education, pain and load monitoring, an activity-ladder approach, symptom-guided exercise progression, motor-control training, basic strength exercises, and gradual return to running, jumping, landing, and sport-specific activities. Exercises are individualized according to symptoms, current activity level, movement quality, treatment tolerance, and clinical judgement.\n\nParticipants will:\n\n1. Attend baseline and follow-up physiotherapy assessments.\n2. Receive an individualized rehabilitation plan with education, pain and load monitoring, and home exercises.\n3. Complete home exercises and keep a short symptom and activity log.\n4. Attend in-person physiotherapy review visits during the rehabilitation period.\n5. Answer questionnaires about pain, function, perceived change, and sports participation during follow-up.",[28,29,30],"Osgood-Schlatter Disease","Sever's Disease","Apophyseal Pain",[28,29,32,33,34,35,30,36,37,38,39],"Knee Pain","Heel Pain","Return to Sport","Load Management","Youth Athletes","Exercise Therapy","Physical Therapy","Rehabilitation","NOT_YET_RECRUITING","2026-05-16",{"date":43,"type":44},"2026-05-20","ACTUAL",{"date":43,"type":22},{"date":47,"type":22},"2029-04-05",{"name":49,"class":50},"Medical University of Gdansk","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":51},"100627275","low-level-laser-therapy-for-osgood-schlatter-or-sever-pain-in-youth-athletes-100627275","NCT07446517","Low-Level Laser Therapy for Osgood-Schlatter or Sever Pain in Youth Athletes","Effect of Low-Level Laser Photobiomodulation on Pain, Function, Ultrasound Findings, and Biochemical Markers in Youth Athletes With Osgood-Schlatter Disease or Sever Disease: A Randomized, Double-Blind, Sham-Controlled Trial","Inclusion Criteria:\n\n* Aged 10 to 17 years\n* Participates in organized sport with at least 12 months of training history\n* Has knee pain at the tibial tubercle (Osgood-Schlatter-type pain) and\u002For heel pain at the back of the heel (Sever-type pain)\n* Pain is worse with activity and reproduced by pressing on the painful area\n* Pain intensity is 3 out of 10 or higher on the Numeric Pain Rating Scale (NPRS) during the clinical visit and in the last week (0 = no pain, 10 = worst pain imaginable)\n* Symptoms have been present for at least 2 weeks\n* For heel pain consistent with Sever disease, the heel squeeze test is positive\n* Ultrasound shows findings consistent with an apophyseal injury at the painful site\n* Has no signs of acute illness or infection on the assessment day and during the previous 14 days (for example, fever or \"flu-like\" symptoms)\n* A parent\u002Fguardian provides written informed consent\n* The participant provides assent (agreement) to take part\n\nExclusion Criteria:\n\n* Current pain episode started after an acute injury (for example, fall, collision, ankle sprain, or similar trauma)\n* Prior surgery on the lower limb\n* Known diagnosis of patellofemoral pain syndrome (pain around\u002Fbehind the kneecap)\n* Known patellar instability (recurrent kneecap dislocations or giving way)\n* Known complex regional pain syndrome\n* History of lower-limb fracture\n* Ultrasound shows clinically important abnormalities in the assessed area that are not consistent with the target condition (for example, calcifications or other significant findings)\n* Known chronic or systemic disease that may affect the musculoskeletal system (for example, inflammatory joint disease or other clinically significant chronic conditions)\n* Received any of the following in the last 3 months: steroid injection, hydrodilatation, or laser therapy\n* Used non-steroidal anti-inflammatory drugs (NSAIDs) (for example, ibuprofen, naproxen) within the last 14 days, or currently uses them\n* Clinically important abnormal blood test results (complete blood count) that may affect safety or data validity\n* Parent\u002Fguardian or participant does not agree to participate, or withdraws consent\u002Fassent",{"count":60,"type":22},30,[25],"The goal of this clinical trial is to learn if low-level laser therapy (also called photobiomodulation) works to treat knee or heel pain in physically active children and adolescents with Osgood-Schlatter disease or Sever disease. It will also learn about the safety of this treatment. The main questions it aims to answer are:\n\n1. Does low-level laser therapy lower pain more than a sham (placebo) laser treatment?\n2. Does low-level laser therapy improve daily and sport-related function more than a sham laser treatment?\n3. What medical problems, if any, do participants have during the study?\n\nResearchers will compare active low-level laser therapy to a sham (placebo) laser treatment. The sham treatment looks and feels the same but does not deliver therapeutic light. This comparison will show whether the laser therapy works better than placebo.\n\nParticipants will:\n\n* Complete screening and a baseline visit\n* Be randomly assigned to active laser therapy or sham laser therapy\n* Receive a series of treatment sessions over \\[2 weeks\\]\n* Answer short questionnaires about pain and function at baseline and follow-up visits\n* Have ultrasound imaging and\u002For provide blood or urine samples for research measurements\n\nBoth participants and the study team who assess outcomes will not know which treatment group each participant is in until the study ends.",[28,29],[65,66,28,67,68,33,69],"Low-Level Laser Therapy","Photobiomodulation","Apophysitis","Traction Apophysitis","Tibial Tubercle Pain","RECRUITING","2026-03-14",{"date":73,"type":44},"2026-03-17",{"date":75,"type":44},"2026-03-01",{"date":77,"type":22},"2029-02-01",{"name":49,"class":50},{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":23,"phases":91,"briefSummary":92,"conditions":93,"keywords":94,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":4},"100600326","safety-and-efficacy-of-urtica-dioica-cataplasm-in-the-management-of-osgood-schlatter-disease-in-young-athletes-100600326","NCT07096037","Safety and Efficacy of Urtica Dioica Cataplasm in the Management of Osgood-Schlatter Disease in Young Athletes","Evaluation of Safety and Efficacy of Urtica Dioica Cataplasm in the Management of Osgood-Schlatter Disease in Young Athletes: A Study Protocol for Randomized, Double-blind, Placebo Controlled Clinical Trial","Inclusion Criteria:\n\n* Healthy male children between 7 and 15 years of age\n* Active in regular sports practice (e.g., football)\n* Clinically confirmed diagnosis of OSD\n\nExclusion Criteria:\n\n* Known allergy to Urtica dioica\n* Presence of dermatological conditions or lesions on the knees\n* Recent use of anti-inflammatory medications\n* History of immune or chronic inflammatory diseases\n* Diagnosis of any other bone disorder","MALE","7 Years","15 Years",{"count":90,"type":22},90,[25],"The primary objective of this clinical trial is to evaluate the efficacy and safety of a topical Urtica dioica cataplasm in managing knee pain and functional limitations in athletic children diagnosed with Osgood-Schlatter Disease. Efficacy will be assessed through changes in knee pain using the Visual Analog Scale (VAS) and functional outcomes using the Knee Injury and Osteoarthritis Outcome Score (KOOS). Three groups will be tested:\n\n* UDC Group: topical application of Urtica dioica cataplasm\n* Standard Care Group: oral vitamin D supplementation and physical rest\n* Placebo Group: topical application of a placebo cataplasm using Beta vulgaris subsp. cicla",[28],[95,96,97,98],"Urtica dioica","Osgood-Schlatter disease","KOOS-Child","Visual Analogue Scale","2025-07-30",{"date":101,"type":44},"2025-08-01",{"date":103,"type":22},"2025-09-01",{"date":105,"type":22},"2026-09-30",{"name":107,"class":50},"Faculty of Medicine, Sousse",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":115,"sex":17,"minAge":116,"maxAge":88,"enrollmentInfo":117,"targetDuration":4,"studyType":23,"phases":119,"briefSummary":120,"conditions":121,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":4},"100592620","osgood-schlatter-disease-in-athletic-children-100592620","NCT06995794","Osgood-Schlatter Disease in Athletic Children","Effect Of Kinesio Tape Versus Knee Strap on Osgood Schlatter Disease in Athletic Children","Inclusion Criteria:\n\n* Children will be included in the study if they fulfil the following criteria:\n\n  1. A medical diagnosis with Osgood Schlatter disease was made by paediatricians or paediatric orthopaedist.\n  2. Number of the participate children will be 38 children.\n  3. Age ranges from 9 to 15 years.\n\nExclusion Criteria:\n\n* Children will be excluded from the study if:\n\n  1. They had a permanent deformity (bony or soft tissue contractures).\n  2. Children have visual or auditory defects.\n  3. Children with intelligence quotient less than 70.\n  4. Children who had undergone a previous surgical intervention to knee joint.\n  5. A history of epileptic seizure and any diagnosed cardiac or orthopaedic disability that may prevent the use of assessment methods.\n  6. Children who are absent in two sessions.",true,"9 Years",{"count":118,"type":22},2,[25],"This study will be conducted to evaluate the effect of using Kinesio tape versus strapping the knee on pain management",[28],"2025-05-21",{"date":124,"type":44},"2025-05-29",{"date":126,"type":22},"2025-05",{"date":128,"type":22},"2026-05",{"name":130,"class":50},"Kafrelsheikh University"]