[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"osteoarthritis-wrist\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:osteoarthritis-wrist":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,65],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100609655","phase-4-radiotherapy-compared-to-corticosteroid-injection-for-treatment-of-hand-osteoarthritis-100609655",false,"NCT07217405","Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis","Low-Dose Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis","Inclusion Criteria:\n\n* Patient at Mayo Clinic, Rochester, MN\n* Age 50 years or older\n* Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months\n* Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand\n* Ability to complete study questionnaires\n\nExclusion Criteria:\n\n* History of previous surgery to the affected hand(s)\n* Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis\n* Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture\n* Recent injury (within last 1 month) to the affected hand causing current pain\n* History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)\n* Active use of opioid pain medication(s) or oral steroids within the last 3 months\n* Fibromyalgia or central sensitization syndrome\n* Hand CSI or other hand injection within the past 3 months\n* History of hand LDRT within the past 3 months\n* Poorly controlled diabetes (HbA1c \\> 10%)\n* Active infection\n* Current pregnancy","ALL","50 Years",{"count":19,"type":20},165,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand\u002Fwrist osteoarthritis.",[26,27],"Osteoarthritis Hand","Osteoarthritis Wrist","RECRUITING","2026-04-21",{"date":31,"type":32},"2026-04-24","ACTUAL",{"date":34,"type":32},"2025-12-19",{"date":36,"type":20},"2027-10-01",{"name":38,"class":39},"Mayo Clinic","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":64},"100523660","wrist-denervation-vs-exercise-in-wrist-osteoarthritis-100523660","NCT06098586","Wrist Denervation Vs Exercise in Wrist Osteoarthritis","Partial Wrist Denervation Versus Self-managed Exercise Therapy in Patients with Wrist Osteoarthritis: a Randomized Controlled Multicenter Trial","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) \u002F Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis.\n* Radiological signs of osteoarthritis on posteroanterior and lateral radiograph.\n\nExclusion Criteria:\n\n* Previous PIN or AIN neurectomy.\n* Rheumatoid arthritis or other chronic inflammatory arthritis.\n* Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints.\n* Ongoing infection.\n* Inability to co-operate with the follow-up protocol.\n* Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment.","18 Years",{"count":50,"type":20},140,[52],"NA","A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.",[27],"2025-02-19",{"date":57,"type":32},"2025-02-21",{"date":59,"type":32},"2023-11-15",{"date":61,"type":20},"2027-11-15",{"name":63,"class":39},"Karolinska Institutet",2,{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":16,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":80,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":95},"100368250","norwegian-distal-ulna-resection---replacement-study-100368250","NCT04074863","Norwegian Distal Ulna Resection - Replacement Study","Norwegian Distal Ulna Resection vs. Replacement Study. A Prospective Randomized Multicenter Study","NORDURR","Inclusion Criteria:\n\n* painful osteoarthritis distal radioulnar joint\n* stable DRUJ\n\nExclusion Criteria:\n\n* activ inflammatory disease with significant destruction of the joint\n* \"low demand\" persons\n* significant instability i DRUJ\n* active infections, poor soft tissue conditions\n* accidental wound on the operated hand\n* general contraindications for surgery","30 Years","75 Years",{"count":76,"type":20},40,[52],"Osteoarthritis of the joint between the forearm bones at the wrist (distal radioulnar joint, DRUJ) is a common sequel of fracture and ligament injuries or degenerative disease of the wrist. Intact DRUJ is important for normal load transfer from the hand to the forearm. DRUJ osteoarthritis leads to pain and decreased lifting capacity and rotation of the forearm. The standard treatment is resection of the ulnar head, known as the Darrach procedure. After the resection there is no longer contact in the affected joint, however, some patients can experience instability or impingement between the forearm bones. With ulnar head implant replacement may the load transfer and the stability between the forearm bones less affected. Studies with good long term results are published with both resection and replacement. However, these methods were never compared and thus it is not clear, which of the methods gives the best clinical result and less complications.\n\nThe aim of this study is to compare Darrach procedure with ulnar head replacement in a prospective randomized multicenter study. Several hand surgical centers form Norway would participate this study.\n\nIndividuals seeking treatment for their stable but painful DRUJ joints will be included and randomized to either Darrach procedure or ulnar head implant. Participants will be followed up to 5 years. Range of motion and grip strength measures and functional scores would be registered before operation, after 3 months, 1 and 5 years. Eventual complications and reoperations would be also registered.",[27],[81,82,83,84,85],"Distal radioulnar joint","Darrach procedure","Ulnar head resection","Herbert prosthesis","Ulnar head replacement","2024-04-05",{"date":88,"type":32},"2024-04-08",{"date":90,"type":32},"2020-09-16",{"date":92,"type":20},"2029-12-31",{"name":94,"class":39},"Ostfold Hospital Trust",6]