[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"osteoarticular-infections\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:osteoarticular-infections":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100601222","prosthetic-joint-infection--lessons-from-deceased-patients-in-critical-care-100601222",false,"NCT07107685","Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.","Osteoarticular Sepsis In Intensive Care Units : a Retrospective Study About Deceased Patients.","OASIS²","Inclusion Criteria:\n\n* Patient aged 18 years or older.\n* Hospitalization in critical care (intensive care unit or continuing care unit) between 2018 and 2022, lasting at least 48 hours, with a prosthetic joint infection (hip, knee, or shoulder prosthesis infection) as the primary or associated diagnosis.\n* Deceased patient who had not refused data processing.\n\nExclusion Criteria:\n\n* Infection involving osteosynthesis material\n* Infection involving spinal instrumentation\n* Patient with multiple infected prostheses\n* Recurrence of prosthetic infection with the same microorganism as a previous episode\n* Patient under legal protection\n* Pregnant or breastfeeding patient\n* Patient deprived of liberty","ALL","18 Years",{"count":20,"type":21},150,"ESTIMATED","OBSERVATIONAL","This is an observational, retrospective, multicenter study based on the use of demographic, clinical and biological data from deceased patients admitted between 2018 and 2022 to critical care with a principal or associated diagnosis of joint prosthesis infection.\n\nData from this study will be combined with that from the OASIS study (APHP241174\u002F ID-RCB: 2024-A01769-38) concerning osteoarticular sepsis on prosthetic material in critical care of living patients.\n\nThe aim of this study is to improve our knowledge of the profile, care trajectories and outcomes of patients hospitalized in critical care in the context of osteoarticular material sepsis.\n\nThe results of the study could help identify at-risk populations and improve management strategies for patients with osteoarticular sepsis.",[25,26,27],"Osteoarticular Infections","Intensive Care Patients","Prosthetic Joint Infection",[29,30,31,32,33,34],"Osteoarticular sepsis","sepsis","osteoarticular prothetis","intensive care","critical care","prosthetic joint infection","RECRUITING","2026-05-29",{"date":38,"type":39},"2026-06-01","ACTUAL",{"date":41,"type":39},"2025-09-24",{"date":43,"type":21},"2026-09-24",{"name":45,"class":46},"Assistance Publique - Hôpitaux de Paris","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":47},"100570770","model-informed-individualized-treatment-of-anti-infective-drugs-100570770","NCT06711562","Model-informed Individualized Treatment of Anti-infective Drugs","Model-informed Individualized Treatment of Anti-infective Drugs in Patients With Osteoarticular Infections","Inclusion Criteria:\n\n* Patients with suspected\u002Fconfirmed osteoarticular infections who are undergoing anti-infective drug therapy.\n\nExclusion Criteria:\n\n* Pregnant\u002Flactating women.\n* There are other factors that the researchers think are not suitable for inclusion.",{"count":56,"type":21},300,"The study aims to optimize individualized treatment of anti-infective drugs in osteoarticular infections by analyzing drug exposure in patients blood and\u002For tissues using population pharmacokinetics.",[25],"2024-11-29",{"date":61,"type":39},"2024-12-02",{"date":63,"type":39},"2024-10-12",{"date":65,"type":21},"2026-10-01",{"name":67,"class":46},"Shandong University"]