[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"outcome-assessment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:outcome-assessment":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,51,87,109,130,160],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100640122","exploration-of-acceptability-of-alcohol-interventions-100640122",false,"NCT07580378","Exploration of Acceptability of Alcohol Interventions","A Mixed-methods Study Exploring the Acceptability of Psychosocial Interventions and Social Determinants of Engagement With an NHS-led Alcohol Care Service.","Inclusion Criteria:\n\n* Clinical staff who worked in the ELHT alcohol care service, and received training in the delivery of psychosocial interventions using the ITEP Manual, and who are still employed by ELHT in other roles (following de-commissioning of the alcohol care service).\n* Patient data under part 2 of the study, who have not opted to have their data removed, in accordance with the NHS MESH, opt out scheme.\n\nExclusion Criteria:\n\n* Clinical staff who worked in the ELHT alcohol care service, but who no longer work for the trust, or are retired.\n* Clinical staff who did not receive training in the delivery of psychosocial interventions.\n* Any patient data under part 2 of the study, who have opted to have their data removed for use, under the NHS MESH protocols.",true,"ALL","18 Years","67 Years",{"count":21,"type":22},2000,"ESTIMATED","OBSERVATIONAL","This is a mixed-methods study consisting of a qualitative assessment the acceptability of psychosocial interventions, delivered by clinical staff. The study will also investigate the correlation between demographic variables and engagement with a North West England, NHS-led, alcohol care service, amongst the patient population.",[26,27,28,29,30,31,32,33,34,35,36,37],"Alcohol Misuse","Alcohol Use Disorder","Behaviour Change","Health Behaviour","Brief Intervention","Outcome Assessment","Social Determinants of Health","Psychosocial Intervention","Socioeconomic Factors","Primary Healthcare","Primary Heath Care","Problem Behavior","NOT_YET_RECRUITING","2026-05-05",{"date":41,"type":42},"2026-05-12","ACTUAL",{"date":44,"type":22},"2026-05-01",{"date":46,"type":22},"2026-06-10",{"name":48,"class":49},"East Lancashire Hospitals NHS Trust","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":63,"studyType":23,"phases":4,"briefSummary":64,"conditions":65,"keywords":73,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":50},"100600102","rehabilitation-practices-in-critically-ill-patients-receiving-invasive-mechanical-ventilation-in-the-intensive-care-unit-100600102","NCT07093125","Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.","An Observational Study on Rehabilitation Practices in the ICU for Critically Ill Patients Undergoing Invasive Mechanical Ventilation - Report (REPOrt)","REPOrt","Inclusion Criteria:\n\n* Patients admitted to a participating ICU\n* Adult patients (aged 16 years or older, depending on local regulations for the definition of \"adults\")\n* Patients who have received invasive ventilation for at least 48 hours\n* Patients who have obtained written informed consent from the patient or next of kin (if local legislation demands so)\n\nExclusion Criteria:\n\n• Patients admitted for withdrawn of life sustain therapy","16 Years","100 Years",{"count":62,"type":22},2400,"28 Days","This international, multicenter, observational study aims to describe rehabilitation practices in Intensive Care Units (ICUs) worldwide.\n\nThe primary objective is to provide an overview of current rehabilitation strategies used in ICUs globally.\n\nSecondary objectives include assessing the relationship between rehabilitation and key ICU outcomes such as ICU and hospital mortality, length of stay, duration of invasive ventilation, extubation failures, and long-term outcomes including quality of life and functional performance 28 days post-ICU discharge.\n\nThe study will also compare rehabilitation practices across different geographic and economic regions to identify potential disparities. The study is structured into three modules, with participation contingent on local resources and feasibility.\n\nThe BASIC Module (mandatory for all centers) gathers fundamental data on rehabilitation practices and their association with patient outcomes.\n\nThe EXTENDED Module (optional) collects more detailed information on the type, timing, duration, and safety of rehabilitation interventions, including passive exercises, active mobilization, respiratory therapies, dysphagia training, occupational therapy, and cognitive support.\n\nThe EXTENDED FOLLOW-UP Module (optional) evaluates the patient's quality of life and functional recovery 28 days after ICU discharge. By examining global rehabilitation practices and their impact on patient outcomes, this study aims to improve rehabilitation strategies in ICUs, contributing to better patient care, recovery, and long-term health outcomes.",[66,67,68,69,31,70,71,72],"Mechanical Ventilation","Pulmonary Rehabilitation","Intensive Care Units (ICUs)","Quality of Life (QOL)","Extubation Failure","Mortality","Critical Care",[74,66,75,76],"Pulmonary rehabilitation","Intensive Care Unit (ICU)","Rehabilitation Outcomes","RECRUITING","2026-04-27",{"date":80,"type":42},"2026-05-04",{"date":82,"type":42},"2025-10-01",{"date":84,"type":22},"2029-10-01",{"name":86,"class":49},"Universita degli Studi di Genova",{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":4,"eligibilityCriteria":93,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":94,"enrollmentInfo":95,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":4},"100631247","thai-baby-study-phase-1-100631247","NCT07498192","Thai Baby Study Phase 1","National Situational Analysis of Birth Mode and Infant Outcomes in Thailand","Inclusion Criteria:\n\n* Mother-infant dyads with delivery records available in the national health administrative database.\n* Deliveries occurring in public hospitals in Thailand during the study period.\n* Records containing information on mode of delivery and linked maternal and infant outcomes.\n\nExclusion Criteria:\n\n* Records with missing or invalid delivery mode information.\n* Records that cannot be reliably linked between mother and infant.","120 Years",{"count":96,"type":22},10300,"The goal of this observational study is to examine national trends in mode of delivery and to assess associations between cesarean section and early-life health outcomes using routinely collected health data in Thailand. The study includes mother-infant dyads delivering in public hospitals across Thailand.\n\nThe main questions it aims to answer are:\n\nIs cesarean delivery associated with increased risk of adverse neonatal outcomes compared with vaginal delivery?\n\nIs cesarean delivery associated with differences in early-life healthcare utilization and breastfeeding outcomes during the first year of life?\n\nResearchers will compare infants born by cesarean section with infants born by vaginal delivery to evaluate differences in neonatal morbidity, healthcare utilization, and breastfeeding patterns.\n\nParticipants will not receive any intervention. The study involves secondary analysis of de-identified national health administrative and clinical data, including delivery records and linked maternal and infant health outcomes.",[31],"2026-03-23",{"date":101,"type":42},"2026-03-27",{"date":103,"type":22},"2026-03-01",{"date":105,"type":22},"2026-12-31",{"name":107,"class":108},"Mead Johnson Nutrition","INDUSTRY",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":115,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":117,"conditions":118,"keywords":119,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":50},"100618247","outcomes-of-robotic-assisted-urological-surgery-100618247","NCT07329140","Outcomes of Robotic-Assisted Urological Surgery","Inclusion Criteria: Patients who underwent robotic-assited urological surgery -\n\nExclusion Criteria: age under 18\n\n\\-",{"count":116,"type":22},5000,"Retrospective review of the patients who underwent urological robotic surgeries.",[31],[120],"robotic","2025-12-28",{"date":123,"type":42},"2026-01-09",{"date":125,"type":42},"2025-12-04",{"date":127,"type":22},"2030-12-31",{"name":129,"class":49},"National Taiwan University Hospital",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":17,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":141,"phases":142,"briefSummary":144,"conditions":145,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":50},"100574800","safety-and-efficacy-of-connecting-the-residual-ear-to-the-cartilage-scaffold-in-first--vs-second-stage-surgery-100574800","NCT06763991","Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery","Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery : a Protocl of a Randomized Controlled Trial in Non-expanded Auricular Reconstruction for Concha-type Microtia","Inclusion Criteria:\n\nAll consecutive patients between 6 and 30 years with a congenital concha-microtia8, admitted to our hospital are potentially eligible, and enrollment in the study will be based on the following criteria.\n\n1. Patients were fully informed about the purpose, modalities and risks associated with this study, signed an informed consent form and were willing to be followed up.\n2. Contrast-enhanced computed tomography (CT) scan shows he or she has 3.Patients can tolerate general anesthesia without severe chronic organic or mental illness.\n\nExclusion Criteria:\n\n1. Patients combined with other ear diseases such as ear fistula, titis media, etc.\n2. Patients receive other unrelated ear surgeries during the study\n3. Skin in the surgical area with infection, ulceration, and scarring.","6 Years","30 Years",{"count":140,"type":22},78,"INTERVENTIONAL",[143],"NA","Eligible patients will be admitted from the outpatient clinic to complete the relevant examinations after admission（Preoperative routine examination and chest CT）. The baseline parameters will be registered when admitted to hospital, including case number, diagnosis, sex, age, height, weight, and underlying medical conditions. Patients have at least 12 hours to consider participation in the study and will be given the opportunity to ask questions about the study. Written informed consent will be obtained by the surgical resident or the surgeon after admission to the hospital.\n\nRandomization will be done by relevant member . After inclusion, patients will be allocated to one of the two study groups (First-stage Connection or Second-stage Connection) using an online randomization program. The perioperative care will be the same for all included patients.Surgery will be performed by experienced surgeons, with non-expanded ear reconstruction using autologous rib cartilage. The surgery normally comprises two stages. After each surgery, details and duration of the surgery will be documented. For each stage of surgery, patients are scheduled for visits about 3-6 months. In addition, after the total surgery, patients are to fill out 'Glasgow Benefit Inventory' and 'Patient and Observer Scar Assessment Scale'.",[146,31,147,148,149,150],"Microtia","RCT","Surgery Related Complications Rate","Treatment Outcome","Reconstruction","2025-05-15",{"date":153,"type":42},"2025-05-16",{"date":155,"type":22},"2025-06-01",{"date":157,"type":22},"2027-02-20",{"name":159,"class":49},"Sichuan Provincial People's Hospital",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":168,"targetDuration":170,"studyType":23,"phases":4,"briefSummary":171,"conditions":172,"keywords":177,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":196},"100579374","advancing-knowledge-in-ischemic-stroke-patients-on-oral-anticoagulants-100579374","NCT06823466","Advancing Knowledge in Ischemic Stroke Patients on Oral Anticoagulants","Advancing Knowledge in Ischemic Stroke Patients on Oral Anticoagulants - The ASPERA International Registry","ASPERA","Inclusion Criteria:\n\n* Age ≥18 years at the time of the index ischemic stroke.\n* Confirmed diagnosis of ischemic stroke according to the World Health Organization (WHO) definition.\n* Availability of at least one neuroimaging exam (either a non-contrast computed tomography \\[NCCT\\] or magnetic resonance imaging \\[MRI\\] of the brain) demonstrating one or more ischemic lesions consistent with patient symptoms.\n* Ongoing oral anticoagulation at the time of the index ischemic stroke, defined as the last intake within 48 hours prior to stroke symptom onset for patients on direct oral anticoagulants (DOACs), or an international normalized ratio (INR) of ≥1.5 in patients on vitamin K antagonists (VKAs), regardless of the time elapsed between the last intake and stroke symptom onset.\n* Prior diagnosis of AF or other cardioembolic arrhythmias.\n\nExclusion Criteria:\n\n* Symptoms not indicative of acute stroke (i.e., syncope, tonic or clonic activity, dizziness alone, confusion and amnesia alone, chronic or subacute development of focal neurological deficit).\n* Ongoing parenteral (intravenous or subcutaneous) anticoagulation at the time of the index event, including bridging with heparin in patients initiating VKA.",{"count":169,"type":22},200,"5 Years","The Advancing knowledge in ischemic Stroke PatiEnts on oRal Anticoagulants (ASPERA) study aims to investigate characteristics of ischemic stroke cases occurring in patients on oral anticoagulation for atrial fibrillation (AF) or other cardioembolic arrhythmias and to characterize short and long-term outcomes associated with different secondary prevention strategies to prevent stroke recurrences. The ASPERA study is a multicenter, observational, both retrospective and prospective real-world study involving acute ischemic stroke patients occurring on oral anticoagulation. The study will encompass a retrospective (ASPERA-R) and prospective (ASPERA-P) data collection. Patient will be recruited consecutively at different emergency services and stroke units worldwide. University of L'Aquila (UnivAQ) will be in charge of study coordination, data analysis and management. The duration of ASPERA-R will be of 5-year from the study initiation of the study. Participating centers will be given a 6-month timeframe to enter retrospective data, commencing from the date of study approval.\n\nASPERA-P duration will be of 2 years of enrollment from the study approval and follow-up of 5 years. (study conclusion after 7 years of approval). Inclusion criteria will be: 1.Confirmed diagnosis of ischemic stroke. 2. Availability of at least one neuroimaging exam positive for ischemic lesion(s) consistent with patient symptoms. 3. Ongoing oral anticoagulation at the time of the index ischemic stroke. 4. Prior diagnosis of atrial fibrillation or other cardioembolic arrhythmias. 5. Written informed consent provided by the patient himself or by proxy. Patients with Symptoms not indicative of acute stroke, ongoing intravenous or subcutaneous anticoagulation at the time of stroke will be excluded. ASPERA-R: characterization of demographic, clinical and neuroimaging features of ischemic stroke cases occurring on oral anticoagulants. The primary outcome will be: ASPERA-R : characterization of demographic, clinical and neuroimaging features of ischemic stroke cases occurring on oral anticoagulants. ASPERA-P: risk of ischemic stroke recurrence of ischemic stroke cases occurring on oral anticoagulants across different secondary preventive strategies (i.e., maintaining the same type of oral anticoagulation versus switching to a different secondary prevention strategy) at 90 days, 1 and 5 years after the index stroke. Additionally, the study will aim to investigate the risk of safety events (hemorrhagic transformation, intracranial hemorrhage, other major bleeding events, any bleeding events, death due to any cause), risk of other major ischemic events (transient ischemic attack, myocardial infarction, death due to vascular causes) at each follow-up and to identify demographic, clinical and neuroimaging features of ischemic stroke recurrences.",[173,174,175,31,176],"Ischemic Stroke","Oral Anticoagulation","Atrial Fibrillation (AF)","Clinical Presentations",[178,179,180,181,182,183,184,185,186],"Ischemic stroke","Oral anticoagulation","Atrial fibrillation","Direct oral anticoagulants","Vitamin k antagonists","Outcomes","Prognosis","Clinical characteristics","Secondary prevention","2025-02-17",{"date":189,"type":42},"2025-02-20",{"date":191,"type":42},"2025-02-12",{"date":193,"type":22},"2031-02-12",{"name":195,"class":49},"University of L'Aquila",47]