[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oxygen-saturation-measurement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oxygen-saturation-measurement":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100602946","endotracheal-suctionning-during-positive-pressure-extubation-in-icu-100602946",false,"NCT07130123","Endotracheal Suctionning During Positive Pressure Extubation in ICU","Removal of the Intubation Tube Under Positive Pressure With or Without Endotracheal Suctioning During Extubation in Intensive Care: a Prospective Randomised Controlled Trial","INTENTION","Inclusion Criteria:\n\n* Adult patient\n* Intubated for more than 48 hours\n* Patient for whom extubation is prescribed by the patient's physician\n\nExclusion Criteria:\n\n* Headboard restriction\\>30°.\n* Decision to limit active treatment in advance of reintubation\n* Protected person (under guardianship or curatorship)\n* Person under court protection\n* Persons deprived of liberty\n* Persons not affiliated to a social security scheme\n* Pregnant or breast-feeding woman\n* No co-inclusion with a study whose period of interest is follow-up within 3 hours of extubation.","ALL","18 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this clinical trial is to evaluate endotracheal suctioning during positive pressure extubation in mechanically ventilated adult patients (over 18 years old) in the intensive care unit (ICU). The main question it aims to answer is whether the intervention improves the respiratory oxygenation index (ROX) three hours after extubation compared to no endotracheal suction during positive pressure extubation.\n\nParticipants will only need to be extubated by the nursing team in the ICU. Follow-up will consist of evaluating respiratory rate, pulse oximetry and inspired oxygen fraction for three hours following extubation.",[27,28,29,30,31],"Mechanical Ventilation With Oral Intubation","Weaning Invasive Mechanical Ventilation","Oxygen Saturation Measurement","Rox Index","Extubation",[33,34,35],"rox index","extubation","Suctionning","RECRUITING","2025-12-12",{"date":39,"type":40},"2025-12-19","ACTUAL",{"date":42,"type":40},"2025-10-03",{"date":44,"type":21},"2027-10",{"name":46,"class":47},"Centre Hospitalier Régional d'Orléans","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":48},"100568398","controlled-desaturation-study-for-perin-health-patch-validation-100568398","NCT06680700","Controlled Desaturation Study for Perin Health Patch Validation","Controlled Desaturation Study for Perin Health Patch Pulse Oximetry Validation","Inclusion Criteria:\n\n* Adults aged 18 years to 50 years\n* The subject is in good general health with no evidence of any medical problems,\n* Fully vaccinated for COVID-19\n* Fluent in both written and spoken English\n* Willing and able to provide informed consent,\n* Able to comply with study procedure.\n\nExclusion Criteria:\n\n* Children (under the age of 18)\n* Adults above 50 years old\n* History of heart, lung, kidney, or liver disease.\n* Obesity (BMI \\> 30),\n* Diagnosis of asthma, sleep apnea, or use of CPAP.\n* Diagnosis of Raynaud's disease\n* Unacceptable collateral circulation based on an exam by the investigator (Allen's test).\n* Pregnant, lactating or trying to get pregnant\n* Current smoker\n* History of diabetes\n* Clotting disorder\n* Hemoglobinopathy or history of anemia\n* History of fainting or vasovagal response\n* Any other serious systemic illness\n* Any other condition which, in the opinion of the investigators, would make them unsuitable for the study,\n* Any injury, deformity, or abnormality at the sensor sites that in the opinion of the investigators' would interfere with the sensors working correctly,\n* Any evidence, in the opinion of the investigators, of medical problems or poor general health\n* Any symptoms related to COVID-19\n* No vaccinated for COVID-19\n* Recent injection with methylene blue\n* History of reactions to medical adhesives,\n* Unable or unwilling to provide informed consent,\n* Inability to comply with the study procedure,\n* Non-English Speaker.",true,"50 Years",{"count":59,"type":21},25,"OBSERVATIONAL","This study aims to test the accuracy of the Perin Health Patch (PHP), a non-invasive, chest-worn device that measures blood oxygen levels, by comparing its readings to a standard pulse oximeter device. The PHP device uses light sensors to measure blood oxygen saturation (SpO2), similar to how standard pulse oximeters work, and could allow for continuous remote monitoring at home. Participants in this study will breathe low-oxygen air through a mask to simulate different oxygen levels in a controlled environment. The goal is to see if the PHP device can accurately measure blood oxygen levels under different conditions and meet safety standards set by the FDA and international guidelines.",[29],[64,65,66],"Pulse Oximeter","Oxygen Saturation","Wearable","2024-11-06",{"date":69,"type":40},"2024-11-08",{"date":71,"type":40},"2024-10-21",{"date":73,"type":21},"2025-03-31",{"name":75,"class":76},"Perin Health Devices","INDUSTRY"]