[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oxygenation-index\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oxygenation-index":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100543687","phase-4-effects-of-different-inhaled-oxygen-concentrations-on-lung-function-in-older-patients-after-laparoscopic-gastrointestinal-surgery-under-general-anesthesia-100543687",false,"NCT06359106","Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia","Inclusion Criteria:\n\n* Age not less than 65 years\n* American Society of Anesthesiologists grades I-III\n* No history of drug allergies or abnormal anesthesia.\n* The duration of mechanical ventilation was expected to be more than 2 hours.\n* Laparoscopic Gastrointestinal Surgery\n* The preoperative oxygen saturation was not less than 94%.\n* The patients will be planned to extubate in the operating room.\n\nExclusion Criteria:\n\n* History of acute lung injury or acute respiratory distress syndrome (ARDS) within 3 months.\n* Cardiac function Class IV (New York Heart Association classification)\n* Chronic renal failure (renal cell filtration rate \\\u003C30 ml min-11.73\u002Fm2), severe liver disease\n* Patients with blurred consciousness and cognitive dysfunction\n* Severe coagulation dysfunction.\n* Without preoperative oxygen inhalation, blood oxygen level \\\u003C94%, and severe pulmonary dysfunction\n* Patients with endotracheal tubes were admitted to the intensive care unit (ICU) after surgery.\n* Body mass index (BMI) \\>30kg\u002Fm2\n* Inability to complete the study","ALL","65 Years",{"count":18,"type":19},1176,"ESTIMATED","INTERVENTIONAL",[22],"PHASE4","This was a multicenter, prospective, parallel-grouping, randomized controlled clinical study comparing low FiO2 (40%) and high FiO2 (80%) levels in older patients undergoing laparoscopic gastrointestinal surgery.",[25],"Oxygenation Index","RECRUITING","2026-01-23",{"date":29,"type":30},"2026-01-26","ACTUAL",{"date":32,"type":30},"2024-07-02",{"date":34,"type":19},"2026-06-30",{"name":36,"class":37},"China Medical University, China","OTHER",16,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":15,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":50,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100610878","complications-of-the-alveolar-opening-maneuver-in-children-on-mechanical-ventilation-100610878","NCT07233304","Complications of the Alveolar Opening Maneuver in Children on Mechanical Ventilation","Incidence of Complications From the Alveolar Opening Maneuver in Mechanically Ventilated Children With Respiratory Distress Syndrome","Inclusion criteria:\n\n* Patients under 14 years of age admitted to the HCANK PICU\n* More than 4 hours of invasive mechanical ventilation (IMV)\n* An oxygenation index (OI) ≥4 or an oxygen saturation index (OSI) ≥5\n* Indication for ARM and PEEP as determined by the treating team\n\nExclusion criteria:\n\n* Predicted body weight (PBW) \\>45.5 kg\n* Recent pulmonary resection surgery (\\\u003C7 days)\n* Presence of broncho-pleural fistula or peri-tube leak \\>25% of the tidal volume\n* Hemoglobin decline \\\u003C7 g\u002FdL\n* Patients with congenital or acquired heart diseases with significant intracardiac shunt.","1 Month","14 Years",{"count":49,"type":19},143,"1 Day","OBSERVATIONAL","The objective of this research is to analyze the overall incidence of complications associated with a therapeutic maneuver known as alveolar opening and subsequent titration of positive end-expiratory pressure (PEEP) in pediatric patients with acute respiratory distress syndrome (ARDS). These procedures are part of the standard care provided in the Pediatric Intensive Care Unit (PICU) and are used to improve pulmonary oxygenation and respiratory mechanics. Through this study, we aim to gather information that will help improve the safety and effectiveness of these interventions in critically ill patients.",[54,25,55,56,57,58],"Positive End-expiratory Pressure (PEEP)","Pediatric Intensive Care Unit","Pediatric Acute Lung Injury","Respiratory Distress Syndrome, Pediatric","Complication","2025-11-14",{"date":61,"type":30},"2025-11-18",{"date":63,"type":30},"2025-08-18",{"date":65,"type":19},"2026-08",{"name":67,"class":37},"Hospital de Alta Complejidad en Red",1]