[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pacemaker-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pacemaker-complication":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,38,62],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100322253","a-major-determinant-focused-on-the-ecg-or-echocardiogram-for-picm-and-its-clinical-outcome-picm-syndrome-100322253",false,"NCT03475498","A Major Determinant Focused on the ECG or Echocardiogram for PICM and Its Clinical Outcome (PICM Syndrome)","A Major Determinant Focused on the ECG or Echocardiogram for Pacing-induced Cardiomyopathy (PICM) and Its Clinical Outcome (PICM Syndrome) : Prospective, Multi-center, Observational Cohort Study.","Inclusion Criteria: mandatory (1 and 2) and optional (3 or 4)\n\n1. Willng to participate in the study and able to sign informed consent\n2. Undertaken ECG and echocardiogram including strain before and after device implantation\n\nExclusion Criteria:\n\n1. Less than 18 years of age\n2. Being pregnant or plan to become pregnant\n3. Advanced heart failure waiting in heart transplantation\n4. Have a life expectancy of less than 1 year","ALL","20 Years",{"count":19,"type":20},1000,"ESTIMATED","10 Years","OBSERVATIONAL","Chronic right ventricular pacing has a deleterious effect on left ventricular (LV) function, namely pacing-induced cardiomyopathy (PICM). Several parametes make difference of effect on the occurrence of PICM and its subsequent clinical outcomes. In particular, recognition of a major determinant focused on the ECG or echocardiographic parameters including strain or genetic factor for occurrence of PICM may lead to better identification of patients at high risk. Investigators prospectively enroll a participant with documented high risk of PICM and clinically follow-up to idenify clinical impact of PICM (PICM syndrome) over a long period of time.",[25],"Pacemaker Complication","RECRUITING","2025-09-28",{"date":29,"type":30},"2025-10-02","ACTUAL",{"date":32,"type":30},"2018-01-30",{"date":34,"type":20},"2028-02-28",{"name":36,"class":37},"Eulji University Hospital","OTHER",{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":16,"minAge":45,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":48,"conditions":49,"keywords":4,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":5},"100550592","the-picm-risk-prediction-study---application-of-ai-to-pacing-100550592","NCT06449079","The PICM Risk Prediction Study - Application of AI to Pacing","Predictive Risk Algorithm for Development of Right Ventricular Pacing Induced Cardiomyopathy - a Step Towards Personalized Pacemaker Lead Deployment","Inclusion Criteria:\n\n* All patients who received a pacing device (VVI, DDD, ICD, leadless pacemaker) from the GSTT\u002FRBH\u002FKCH\u002FICH database in the last 10 years (from 01\u002F01\u002F2014)\n* All patients who are \\>18 years old.\n* Male and Female\n\nExclusion Criteria:\n\n* Patients who did not receive a pacing device (VVI, DDD, ICD, leadless pacemaker)\n* All patients \\\u003C18 years old\n* Patients with congenital heart disease\n* Patients who have received artificial heart valves or underwent cardiac bypass surgery\n* Patients who did not have an echocardiogram after receiving a pacing device","18 Years",{"count":47,"type":20},10000,"Development of pacing induced cardiomyopathy (PICM) is correlated to a high morbidity as signified by an increase in heart failure admissions and mortality. At present a lack of data leads to a failure to identify patients who are at risk of PICM and would benefit from pre-selection to physiological pacing. In the light of the foregoing, there is an urgent need for novel non-invasive detection techniques which would aid risk stratification, offer a better understanding of the prevalence and incidence of PICM in individuals with pacing devices and the contribution of additional risk factors.",[50,51,25],"Heart Failure","Pacemaker-Induced Cardiomyopathy","NOT_YET_RECRUITING","2024-06-05",{"date":55,"type":30},"2024-06-07",{"date":57,"type":20},"2024-07-30",{"date":59,"type":20},"2026-10-30",{"name":61,"class":37},"Guy's and St Thomas' NHS Foundation Trust",{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":11,"sex":16,"minAge":45,"maxAge":4,"enrollmentInfo":69,"targetDuration":4,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":86},"100490545","prevention-of-pacemaker-lead-induced-tricuspid-regurgitation-by-transesophageal-echo-guided-implantation-place-100490545","NCT05667519","Prevention of Pacemaker Lead Induced Tricuspid regurgitAtion by Transesophageal eCho guidEd Implantation (PLACE)","PLACE","Inclusion Criteria:\n\n* indication for right ventricular lead implantation according to current guidelines\n\nExclusion Criteria:\n\n* preexisting tricuspid regurgitation ≥ grade 2\n* other severe heart valve disease\n* history of tricuspid valve treatment\n* preexisting right ventricular lead\n* chronic dialysis\n* contraindication for transesophageal echocardiography",{"count":70,"type":20},324,"INTERVENTIONAL",[73],"NA","This is the first randomized controlled trial comparing transesophageal echocardiography + fluoroscopy guided lead implantation vs. standard lead implantation guided by fluoroscopy only. Patients are randomized 1:1 in the two groups and followed up for up to 3 years.",[76,25],"Tricuspid Regurgitation","2022-12-19",{"date":79,"type":30},"2022-12-28",{"date":81,"type":30},"2022-10-01",{"date":83,"type":20},"2027-10",{"name":85,"class":37},"LMU Klinikum",1]