[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-measurement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-measurement":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,90],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100617767","evaluation-of-chronic-postsurgical-pain-risk-in-patients-undergoing-cied-implantation-using-an-aid-support-system-100617767",false,"NCT07322900","Evaluation of Chronic Postsurgical Pain Risk in Patients Undergoing CIED Implantation Using an AID Support System","Evaluation of Chronic Postsurgical Pain Risk in Patients Undergoing Cardiac Implantable Electronic Device (CIED) Implantation Using an Artificial Intelligence-Based Clinical Decision (AID) Support System","PAIN-AID","Inclusion Criteria:\n\n* Adults aged ≥18 years.\n* Patients who have undergone first-time implantation of a cardiac implantable electronic device (CIED), including pacemaker (PM), implantable cardioverter-defibrillator (ICD), or cardiac resynchronization therapy device (CRT).\n* Device implantation performed within the past 12 months at Istanbul University-Cerrahpaşa Cardiology Institute.\n* Ability to attend scheduled follow-up visits at 3, 6, and 12 months post-implantation.\n* Ability to understand study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* History of neuropathic or chronic pain syndromes prior to implantation (e.g., fibromyalgia, diabetic neuropathy).\n* Presence of neurodegenerative, autoimmune, or vascular disorders affecting peripheral or central pain pathways.\n* Known malignancy, active infection, or recent trauma in the chest or upper extremities.\n* Prior CIED replacement or battery exchange procedures.\n* Use of chronic analgesic or neuropathic pain medications (e.g., opioids, gabapentinoids, antidepressants) for conditions unrelated to the procedure.\n* Cognitive impairment or psychiatric disorders that may interfere with study participation or reliable pain assessment.\n* Inability to comply with follow-up or withdrawal of consent at any time.","ALL","18 Years",{"count":20,"type":21},180,"ESTIMATED","15 Months","OBSERVATIONAL","Chronic postsurgical pain (CPSP) remains a significant clinical and public health challenge despite major advances in surgical and anesthetic techniques. Patients receiving cardiac implantable electronic devices (CIEDs)-including pacemakers, implantable cardioverter-defibrillators (ICDs), and cardiac resynchronization therapy devices (CRTs)-constitute a unique population with high rates of multimorbidity, psychological vulnerability, and limited analgesic options due to cardiovascular comorbidities. Insufficient postoperative pain management in this group may lead to persistent pain at the generator site, neuropathic pain features, reduced quality of life, and increased healthcare utilization.\n\nThe present study aims to evaluate the prevalence, risk factors, and clinical predictors of CPSP following CIED implantation using both subjective and objective pain assessments. Pain intensity will be measured using validated self-report scales (Visual Analog Scale and DN-4 questionnaire), and objective pain thresholds will be determined using a calibrated digital pressure algometer. Quality of life will be assessed with the validated Turkish version of the Short Form-12 (SF-12) instrument.\n\nThis prospective observational study will include 180 adult patients who underwent first-time CIED implantation at Istanbul University-Cerrahpaşa, Cardiology Institute. Participants will be evaluated at 3, 6, and 12 months post-implantation. Collected data will include preoperative, intraoperative, and postoperative variables such as demographics, comorbidities, anesthesia type, surgical duration, and acute postoperative pain control.\n\nUsing the obtained data, an artificial intelligence-based clinical decision support system will be developed to predict individual CPSP risk before implantation. The model will integrate subjective scales, objective algometric data, and clinical factors to generate personalized risk estimates. Ultimately, this system aims to improve early detection and prevention of CPSP, optimize postoperative pain management strategies, and enhance patient quality of life.",[26,27,28,29,30],"Pain Measurement","Chronic Pain","Cardiac Implantable Electrical Devices","Neuropathic Pain","Chronic Post Surgical Pain",[32,33,34,27,35,36,37,38],"Cardiac Resynchronization Therapy Devices","Pacemaker, Artificial","Defibrillators, Implantable","Quality of Life","Artificial Intelligence","Decision Support Systems, Clinical","postoperative pain","NOT_YET_RECRUITING","2026-05-04",{"date":42,"type":43},"2026-05-05","ACTUAL",{"date":45,"type":21},"2026-09-30",{"date":47,"type":21},"2027-03-01",{"name":49,"class":50},"Istanbul University - Cerrahpasa","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":89},"100569296","the-effects-of-endotracheal-suctioning-on-pain-and-serum-markers-100569296","NCT06692400","The Effects of Endotracheal Suctioning on Pain and Serum Markers","The Impact of Endotracheal Suctioning on Pain, Hypoxia, and Oxidative Stress Biomarkers in Intubated Adult ICU Patients: A Controlled Trial","Inclusion Criteria:\n\n* Adults (aged 18 years and older)\n* Current diagnosis of flu, pneumonia, COVID, or sepsis\n* Intubated and receiving mechanical ventilation.\n* Have arterial lines placed\n* Require endotracheal suctioning as part of their care\n\nExclusion Criteria:\n\n* Patients receiving neuromuscular blocking agents\n* Contraindications for blood draws (hemoglobin levels below 8.0 g\u002FdL; Jehovah's Witness)",{"count":59,"type":21},110,"INTERVENTIONAL",[62],"NA","The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be uncomfortable and cause stress.\n\nThe main questions this study aims to answer are:\n\nDoes ETT suctioning raise pain levels as measured by the Critical-Care Pain Observation Tool (CPOT)? Does ETT suctioning increase certain chemicals in the blood (hypoxanthine, xanthine, and uric acid) that show stress and lack of oxygen in the body? Researchers will compare patients who have ETT suctioning (intervention group) with those who do not have suctioning during the study period (control group) to see if there are differences in pain and blood markers of stress.\n\nParticipants will:\n\nHave pain measured before and after suctioning using the CPOT. Have blood samples taken from an existing line at three time points: 5 minutes before, 5 minutes after, and 30 minutes after suctioning.\n\nProvide demographic information (like age, gender, and diagnosis) from medical records.\n\nThis research will help improve how pain is managed for ICU patients who cannot speak for themselves, potentially leading to better pain relief methods in the future.",[65,66,67,68,26,69,70,71,72,73,74,75,76,77,78],"Intensive Care Unit ICU","Intubation","Critical Illness","Mechanical Ventilation","Pain, Procedural","Oxidative Stress","Hypoxia","Biomarkers \u002F Blood","Adult","Uric Acid","Sepsis","COVID","Influenza","Pneumonia","RECRUITING","2025-05-19",{"date":82,"type":43},"2025-05-21",{"date":84,"type":43},"2025-01-30",{"date":86,"type":21},"2026-04",{"name":88,"class":50},"Loma Linda University",1,{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":4,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":17,"minAge":97,"maxAge":4,"enrollmentInfo":98,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":89},"100583527","turkish-validation-of-the-geriatric-pain-measure---short-form-100583527","NCT06877481","Turkish Validation of the Geriatric Pain Measure - Short Form","Turkish Adaptation, Validation, and Reliability Assessment of the Geriatric Pain Measure - Short Form","Inclusion Criteria:\n\n* Geriatric patients with chronic pain\n* Patients who agreed to participate in the study\n\nExclusion Criteria:\n\n* Demantia\n* Mental of physical disorders that effect patients answering the scales\n* Diagnosis of malignancy","65 Years",{"count":99,"type":21},150,"This study aims to adapt, validate, and assess the reliability of the Geriatric Pain Measure - Short Form in Turkish. A total of 150 patients aged 65 years and older will complete the scale under the supervision of pain management and gerontology specialists. Reliability and validity will be evaluated using statistical analyses, including internal consistency, test-retest reliability, and correlation with validated pain and sleep scales. Ethical approval has been obtained, and all participants will provide informed consent.",[102,26,27],"Geriatric Assessment",[102,26,27,104],"Geriatric Pain Measurement Short Form","2025-03-18",{"date":107,"type":43},"2025-03-20",{"date":109,"type":43},"2025-03-15",{"date":111,"type":21},"2025-06-15",{"name":113,"class":114},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV"]