[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-score-reduction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-score-reduction":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100640393","stratafix-vs-pds-fascial-closure-rct-100640393",false,"NCT07574086","Stratafix vs. PDS (Fascial Closure RCT)","A Randomized Controlled Trial Comparing Stratafix vs. PDS Suture for Fascial Closure at Cesarean Delivery: Impact on Postoperative Pain and Narcotic Use","Inclusion Criteria:\n\n* Women of reproductive age ( ≥18 years old to ≤ 45 years old) undergoing primary scheduled or unscheduled Cesarean delivery at ≥37 weeks of gestation.\n\nExclusion Criteria:\n\n* Women of reproductive age (≤ 18 years old to ≥ 45 years old) undergoing primary scheduled or unscheduled Cesarean delivery at ≤ 37 weeks of gestation.\n* Emergent Cesarean delivery\n* Chronic opioid use or pain disorders\n* Allergy to suture materials\n* Previous classical Cesarean section\n* Intraoperative complications (e.g. hemorrhage, uterine rupture, injury)",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},200,"ESTIMATED","INTERVENTIONAL",[25],"NA","This proposed prospective, randomized, single-blinded controlled trial will directly compare Stratafix anti-microbial barbed sutures and standard PDS sutures for fascial closure at the time of Cesarean delivery.\n\nPrimary outcomes will include postoperative pain scores at 24 hours, 48 hours, and two weeks postpartum (both total pain and right-sided abdominal pain commonly associated with the knot from traditional fascial closure), as well as total opioid consumption (morphine milligram equivalents) for the first 48 hours.\n\nSecondary outcomes will include length of hospital stay, wound complications (e.g., infection, dehiscence), patient satisfaction measured per the standardized surgical satisfaction questionnaire (SSQ-8), time required for fascial closure (minutes from start to end of fascial closure), and surgical site infections. The hypothesis is that among women undergoing primary Cesarean delivery, fascial closure with barbed suture (Stratafix) will result in lower postoperative pain scores and reduced opioid (narcotic) consumption within the first 48 hours after surgery compared to closure with traditional monofilament suture (PDS).",[28,29],"Pain Score Reduction","Cesarian Section",[29,28,31],"Opiod use","NOT_YET_RECRUITING","2026-05-01",{"date":35,"type":36},"2026-05-07","ACTUAL",{"date":33,"type":22},{"date":39,"type":22},"2031-12-31",{"name":41,"class":42},"University of Arizona","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":51,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":69},"100589633","phase-2-magnesium-sulfate-in-addition-to-bupivacaine-in-ultrasound-guided-transmuscular-quadratus-lumborum-block-for-post-operative-analgesia-after-total-hip-arthroplasty-100589633","NCT06956950","Magnesium Sulfate in Addition to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Post-Operative Analgesia After Total Hip Arthroplasty","Efficacy of Adding Magnesium Sulfate to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Postoperative Analgesia in Patients Underdoing Hip Arthroplasty","Mgso4","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* American Society of Anesthesiology (ASA) class I-III\n* Undergoing hip arthroplasty .\n\nExclusion Criteria:\n\n* Patient refusal.\n* Body mass index (BMI) \\> 40 Kg\u002Fm2.\n* Allergy to local anesthetics or magnesium sulphate.\n* coexisting coagulopathy.\n* Local infection at puncture site.\n* Severe renal impairment ( eGFR \\\u003C 30 ml\u002Fmin)","ALL",{"count":53,"type":22},70,[55,56],"PHASE2","PHASE3","The aim of this clinical trial is to evaluate the efficacy of adding magnesium sulfate to bupivacaine in ultrasound-guided transmuscular quadratus lumborum block for postoperative analgesia in adult patients underdoing hip arthroplasty. The main questions it aims to answer are:\n\n* Does Magnesium sulphate lower Pain score (VAS) postoperatively.\n* Does Magnesium sulphate lowerTotal opioid consumption postoperatively. and What side effects do participants have when taking Magnesium sulphate? Researchers will compare Magnesium sulphate to a placebo (a look-alike substance that contains no drug) to see if Magnesium sulphate works to lower pain score.\n\nParticipants will:\n\n* Take with have ultrasound-guided transmuscular quadratus lumborum block after surgery using bupivacaine with Magnesium sulphate or with placebo\n* Followed up 48 hours postoperatively to monitor pain score or any reported side effect.",[28],"RECRUITING","2025-05-09",{"date":62,"type":36},"2025-05-11",{"date":64,"type":22},"2025-05",{"date":66,"type":22},"2025-11",{"name":68,"class":42},"Tanta University",1]