[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"palatal-wound\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:palatal-wound":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100578039","wound-healing-and-patient-reported-outcomes-after-gingival-graft-harvesting-from-the-palate-100578039",false,"NCT06806111","Wound Healing and Patient-Reported Outcomes After Gingival Graft Harvesting From the Palate","Wound Healing and Patient-Reported Outcomes After Autogenous Gingival Graft Harvesting From the Palate: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Systemically healthy individuals older than 18 years old;\n* Healthy periodontal status according to the AAP\u002FEFP definition;\n* Full-mouth plaque (FMPS) and bleeding scores (FMBS) ≤ 20%;\n* No history of soft tissue harvesting.\n\nExclusion Criteria:\n\n* Pregnancy or lactation;\n* Self-reported smoking ≥10 cigarettes\u002Fday;\n* Metabolic diseases that negatively affect soft tissue healing (i.e., diabetes mellitus);\n* Any medication that may interfere with wound healing;\n* Removable maxillary prostheses;\n* Ongoing orthodontic therapy.","ALL","18 Years",{"count":19,"type":20},66,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to evaluate whether two different techniques for treating palatal wounds-sutures and cyanoacrylate bioadhesive-can influence postoperative morbidity, clinical healing, and soft tissue dimensional changes in patients undergoing epithelialized gingival graft harvesting from the palate. The main questions it aims to answer are:\n\nDoes the use of cyanoacrylate bioadhesive reduce postoperative morbidity compared to sutures? Does the choice of wound treatment technique affect clinical healing and three-dimensional changes in soft tissues? Researchers will compare the sutures (control group) to the cyanoacrylate bioadhesive (test group) to determine if the bioadhesive leads to improved postoperative outcomes.\n\nParticipants will:\n\nUndergo epithelialized gingival graft harvesting from the palate. Receive either sutures or cyanoacrylate bioadhesive for wound closure. Be monitored for postoperative morbidity, clinical healing, and soft tissue dimensional changes.",[26],"Palatal Wound",[28,29,30,31,32],"gingival graft harvesting","wound healing agent","postoperative pain","palatal healing","palatal volumetric changes","RECRUITING","2026-04-05",{"date":36,"type":37},"2026-04-09","ACTUAL",{"date":39,"type":37},"2025-02-03",{"date":41,"type":20},"2026-09",{"name":43,"class":44},"Universitat Internacional de Catalunya","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":45},"100618325","the-effectiveness-of-nano-bio-fusion-gingival-gel-nbf-on-wound-healing-at-the-palate-donor-site-after-soft-tissue-graft-surgery-compared-to-placebo-gel-100618325","NCT07330154","The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.","The Effectiveness of Nano Bio Fusion Gel (NBF) on Early Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel: a Double Blinded Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Patients with gingival recession that is indicated for root coverage or need for phenotype modification.\n2. 18 years or older.\n3. absence of systemic disease\n4. Non-smoker\n5. No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months\n\nExclusion Criteria:\n\n1. Pregnant or lactating woman.\n2. patients with immune or systemic diseases.\n3. Patients with an allergy to any ingredient in the gel.",true,{"count":55,"type":20},36,[23],"The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are:\n\n* Does NBF gel enhance wound healing after graft harvesting from the palate?\n* Does NBF gel reduce the number of inflammatory mediators after surgery?\n* Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing.\n\nStudy steps include:\n\n* Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks.\n* Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30).\n* Wound fluid samples will be collected on days (0, 1, 2, 4, 7).\n* Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.",[59,26,60,61],"Wound Healing","Donor Site Complication","Inflammatory Cytokines",[63,64,65,66],"NBF gel","wound healing","palatal donor site","soft tissue graft","2026-01-21",{"date":69,"type":37},"2026-01-23",{"date":71,"type":37},"2025-10-29",{"date":73,"type":20},"2026-12",{"name":75,"class":44},"King Abdullah University Hospital"]