[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pancreatic-tumor-benign\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pancreatic-tumor-benign":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100633664","association-between-chronic-psychological-stress-and-disease-course-outcomes-in-pancreatic-cancer-100633664",false,"NCT07529626","Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer","A Prospective Cohort Study on the Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer: A Comprehensive Analysis Based on Multidimensional Dynamic Psychological Assessment (MIND-PANC)","MIND-PANC","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Histologically or cytologically confirmed diagnosis of pancreatic cancer, or other pancreatic diseases.\n* Conscious, with basic reading\u002Fwriting or communication skills, able to understand and complete the questionnaire assessments (either independently, with assistance from research staff, or with help from a family member).\n* Voluntarily agree to participate in this study and sign a written informed consent form.\n\nExclusion Criteria:\n\n* Presence of severe cognitive impairment (e.g., dementia, disturbance of consciousness) or a definite history of psychiatric disorders, judged by the investigator as unable to comply with the study assessments, and without a family member who can help complete the questionnaire assessments.\n* Presence of other severe, uncontrolled systemic diseases (e.g., severe heart, lung, or kidney failure), with an estimated life expectancy \\\u003C 3 months as judged by the investigator.\n* Inability to understand Chinese or presence of severe visual\u002Fhearing impairment that affects completion of the questionnaire assessments, and without a family member who can help complete the questionnaire assessments.","ALL","18 Years",{"count":20,"type":21},320,"ESTIMATED","3 Years","OBSERVATIONAL","This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer.\n\nResearchers will ask participants to fill out simple questionnaires about their mood, worries, and sleep at the start of the study and at regular follow-up visits. The study will also collect a small blood sample (leftover from routine care) to measure stress-related markers.\n\nInvestigators hypothesize that pancreatic cancer patients who have higher levels of ongoing psychological stress (such as anxiety, depression, or poor sleep) tend to have shorter survival times, a higher chance of recurrence, and a poorer response to treatment, compared to patients with lower stress levels.",[26,27,28],"Pancreatic Tumor, Benign","Pancreatic Cancer, Adult","Pancreatic Cancer Resectable",[30,31,32,33,34,35,36,37,38],"pancreatic cancer","anxiety","depression","psychological distress","Hospital Anxiety and Depression Scale","Pittsburgh Sleep Quality Index","disease progression","Overall survival","quality of life","RECRUITING","2026-06-24",{"date":42,"type":43},"2026-06-29","ACTUAL",{"date":45,"type":43},"2026-05-11",{"date":47,"type":21},"2028-12-31",{"name":49,"class":50},"Shanghai Zhongshan Hospital","OTHER",3,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":4},"100528949","comparison-of-kimura-versus-warshaw-technique-for-laparoscopic-spleen-preserving-distal-pancreatectomy-100528949","NCT06167421","Comparison of Kimura Versus Warshaw Technique for Laparoscopic Spleen-Preserving Distal Pancreatectomy","Comparison of Kimura Versus Warshaw Technique for Laparoscopic Spleen-Preserving Distal Pancreatectomy: A Multicenter Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Age between 18 and 70 years, regardless of gender.\n* Preoperative clinical diagnosis of benign or low-grade malignant pancreatic tumors.\n* Meeting the recommended surgical indications as per guidelines.\n* Feasibility of imaging assessment for either Kimura or Warshaw technique laparoscopic spleen-preserving distal pancreatectomy.\n* Performance status of 0 or 1 according to the Eastern Cooperative Oncology Group (ECOG) score.\n* Willingness to comply with the study treatment plan, follow-up schedule, and other protocol requirements.\n* Voluntarily participating in the study and signing an informed consent form.\n\nExclusion Criteria:\n\n* Body Mass Index (BMI) \\> 28 kg\u002Fm2 (Chinese obesity standard).\n* History of blood disorders, acute or chronic pancreatitis, gastrointestinal bleeding, splenic rupture, or gastric varices (preoperative CT indicating curved vessel structures along the gastric wall with a diameter \\> 5mm).\n* History of abdominal surgery.\n* Concomitant primary malignant tumors.\n* Suspicion of malignancy based on PET-CT or other imaging examinations.\n* Severe impairment of cardiac, liver, or kidney function (NYHA class 3-4, ALT and\u002For AST exceeding three times the upper limit of normal, Creatinine exceeding the upper limit of normal).\n* Planned pregnancy or pregnancy and lactating women.\n* Participants currently involved in other clinical trials.","70 Years",{"count":61,"type":21},240,"INTERVENTIONAL",[64],"NA","This study aims to compare the surgical outcomes of laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique versus the Warshaw technique. The primary focus is on the rates of unplanned splenectomy, occurrence of severe complications, as well as intraoperative and perioperative outcomes of both techniques.",[26,67,68],"Pancreatic Neuroendocrine Tumor","Solid Pseudopapillary Tumor of the Pancreas",[70,71,72,73,74],"Pancreatic benign or low-grade malignant tumors","Minimally invasive spleen-preserving distal pancreatectomy","Kimura technique","Warshaw technique","Prognosis","NOT_YET_RECRUITING","2023-12-04",{"date":78,"type":43},"2023-12-12",{"date":80,"type":21},"2024-01-01",{"date":82,"type":21},"2027-12-31",{"name":84,"class":50},"Fudan University"]