[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pao2\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pao2":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100616775","postoperative-hypoxemia-increases-the-risk-of-anastomotic-leak-after-radical-esophagectomy-100616775",false,"NCT07309991","Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy","Inclusion Criteria:\n\n* Patients diagnosed with esophageal carcinoma or benign esophageal tumors\n* Patients requiring surgical resection of the lesion with subsequent esophageal reconstruction\n* Patients must have had at least one postoperative arterial blood gas analysis\n* Patients must have routinely undergone at least one of the following for postoperative evaluation of the anastomosis: endoscopy, CT scan, or esophagram\n\nExclusion Criteria:\n\n* Patients who did not require esophageal reconstruction\n* Patients undergoing esophageal replacement with colon\n* Patients with incomplete data","ALL","18 Years","80 Years",{"count":19,"type":20},2500,"ESTIMATED","OBSERVATIONAL","This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\\\u003C80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. The investigators conducted a retrospective analysis of cases from their center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.",[24,25,26,27,28],"Esophageal Carcinoma","Esophageal Adenocarcinoma","Esophagectomy","PaO2","Esophageal Anastomotic Leakeage",[30],"Effect of Postoperative PaO₂ on Anastomotic Leakage Following Esophagectomy","RECRUITING","2026-06-13",{"date":34,"type":35},"2026-06-16","ACTUAL",{"date":37,"type":35},"2021-01-01",{"date":39,"type":20},"2026-12-01",{"name":41,"class":42},"Sun Yat-sen University","OTHER",6]