[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"paraspinal-muscles\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:paraspinal-muscles":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100621307","transcutaneous-electrical-nerve-stimulation-tens-for-the-treatment-of-low-back-pain-lbp-in-adults-100621307",false,"NCT07368920","Transcutaneous Electrical Nerve Stimulation (TENS) for the Treatment of Low Back Pain (LBP) in Adults","A Prospective, Open-Label, Single-Arm, Self-Controlled Study of Transcutaneous Electrical Nerve Stimulation (TENS) for Adult Low Back Pain","Inclusion Criteria:\n\n1. Adults aged 18-65 years\n2. Diagnosis consistent with myofascial low back pain (localized low back pain with a palpable taut band; referred pain and\u002For sensory changes near a specific trigger point; an identifiable tender spot within the taut band; mild muscle weakness and\u002For some limitation of joint range of motion)\n3. Mild pain intensity at baseline (VAS \\\u003C 4 on a 0-10 scale)\n4. Symptom duration \\> 1 month\n5. Able to understand the study procedures and demonstrate good compliance\u002Fcooperation\n6. Written informed consent provided\n\nExclusion Criteria:\n\n1. Low back pain due to other causes, including but not limited to lumbar disc herniation, lumbar spinal stenosis, ankylosing spondylitis, spinal tumor, spinal tuberculosis, or spinal infection\n2. Received physical therapy, interventional procedures, or medication treatment within 4 weeks prior to enrollment that may affect pain or function assessment\n3. Systemic disease or organ dysfunction\n4. Skin\u002Fsoft tissue breakdown or infection at\u002Fnear the planned treatment area\n5. Use of sedative medications or opioid analgesics within 6 months prior to enrollment, or currently receiving other treatments that may affect study outcomes\n6. Severe psychiatric disorder or inability to cooperate with study procedures\n7. Pregnant or breastfeeding women","ALL","18 Years","65 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to assess the effects and safety of transcutaneous electrical nerve stimulation (TENS) in adults with myofascial low back pain. Eligible participants will receive TENS treatment 5 times per week for 4 weeks. Pain intensity and functional outcomes will be assessed at baseline and weekly during the 4-week treatment period, and adverse events will be recorded.",[27,28,29],"Low Back Pain","Paraspinal Muscles","CLBP - Chronic Low Back Pain",[31,32,33],"Low back pain","Transcutaneous electrical stimulation","Self-controlled clinical trial","RECRUITING","2026-03-19",{"date":37,"type":38},"2026-03-20","ACTUAL",{"date":40,"type":38},"2026-02-01",{"date":42,"type":21},"2029-01-01",{"name":44,"class":45},"Xijing Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100620111","multimodal-exercise-therapy-for-non-surgical-intervention-of-nonspecific-low-back-pain-100620111","NCT07353372","Multimodal Exercise Therapy for Non-Surgical Intervention of Nonspecific Low Back Pain.","Interventional Study on Paraspinal Muscle Degeneration Leading to Lumbar Degenerative Diseases","METNLBP","Inclusion Criteria:\n\n1. Age ≥ 60 years\n2. Chronic low-back pain for \\> 3 months (no surgical indication)\n3. Planned to receive conservative treatment\n4. Willing to participate and able to provide written informed consent\n\nExclusion Criteria:\n\n1. Specific low-back pain due to infection, tumour, fracture, ankylosing spondylitis, scoliosis, or other structural spinal disorders\n2. Previous lumbar surgery or current surgical indication for lumbar disease 3.Severe cardiopulmonary, hepatic or renal insufficiency that precludes exercise or drug therapy\n\n4.Severe cognitive impairment or psychiatric disorder preventing cooperation 5.Marked exercise limitations or physical disability precluding rehabilitation training 6.Participation in another clinical trial that could interfere with outcomes 7.Known hypersensitivity to any study medication","60 Years",{"count":57,"type":21},314,[24],"This multicenter, assessor-blinded, two-arm parallel randomized controlled trial (N = 314) will compare the efficacy and safety of a 6-week multidimensional exercise program plus usual pharmacological care (experimental arm) versus usual pharmacological care alone (control arm) in adults ≥ 60 years with chronic non-specific low-back pain (LBP) and imaging evidence of paraspinal muscle degeneration. The primary endpoint is change in Oswestry Disability Index (ODI) at 12 months. Secondary endpoints include pain VAS, JOA score, recurrence rate, and patient satisfaction measured repeatedly to 12 months. Advanced MRI radiomics and machine-learning algorithms will be used to build a \"paraspinal muscle imaging-function-prognosis\" prediction model and an open-access web tool for risk stratification. The study will generate a standardized, evidence-based non-operative care pathway for chronic LBP driven by paraspinal muscle degeneration",[28,27,61,62,63],"Machine Learning","Radiomics","Non-surgical Treatment",[65,66],"Nonsteroidal anti-inflammatory drugs","Multidimensional exercise intervention","NOT_YET_RECRUITING","2026-01-19",{"date":70,"type":38},"2026-01-20",{"date":72,"type":21},"2026-01-01",{"date":74,"type":21},"2028-09-01",{"name":76,"class":45},"Xuanwu Hospital, Beijing",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":46},"100593167","the-impact-of-paraspinal-muscle-atrophy-in-spine-surgeries-100593167","NCT07002918","The Impact of Paraspinal Muscle Atrophy in Spine Surgeries","The Impact of Paraspinal Muscle Atrophy in Lumbar Spinal Fusion Outcomes","Inclusion Criteria:\n\n* Patients with degenerative lumbar spine diseases undergoing lumbar spinal fusion.\n\nExclusion Criteria:\n\n* Long-level fusion ≥ 3 levels.\n* History of previous lumbar surgery.\n* Patients diagnosed with spondylolysis.\n* Other pathological conditions such as fractures, infections or tumors.\n* Uncontrolled comorbidities.",{"count":85,"type":21},55,"OBSERVATIONAL","The goal of this observational study is to learn about the role of pre-operative paraspinal muscle atrophy in outcomes of lumbar spine fusion surgeries in patients with degenerative lumbar spine diseases. The main question it aims to answer is:\n\nDoes paraspinal muscle atrophy worsen lumbar spine fusion surgeries outcomes? Participants undergoing lumbar spine fusion surgeries as part of their treatment for degenerative lumbar spine diseases will answer survey questions about their low back pain and daily activities for 1 year.",[28,89],"Degenerative Lumbar Diseases",[91,92,93],"paraspinal muscles atrophy","Degenerative lumbar spine diseases","lumbar spine fusion","2025-05-25",{"date":96,"type":38},"2025-06-04",{"date":98,"type":21},"2025-06",{"date":100,"type":21},"2027-09",{"name":102,"class":45},"Assiut University"]