[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parathyroid-adenomas\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parathyroid-adenomas":20},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,29,58],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":4,"targetDuration":4,"studyType":17,"phases":4,"briefSummary":18,"conditions":19,"keywords":4,"overallStatus":21,"whyStopped":4,"lastUpdateSubmitDate":22,"lastUpdatePostDateStruct":23,"startDateStruct":4,"completionDateStruct":4,"leadSponsor":26,"locationsCount":4},"100609718","expanded-access18f-fluorocholine-for-the-detection-of-parathyroid-adenomas-100609718",false,"NCT07218224","Expanded Access:18F-Fluorocholine for the Detection of Parathyroid Adenomas","Inclusion Criteria:\n\n1. Age ≥ 13 years.\n2. Evidence of primary hyperparathyroidism.\n3. Ability to understand a written informed consent document, and the willingness to sign it.\n\nExclusion Criteria:\n\n1\\. Unlikely to comply with protocol procedures, restrictions and requirements and judged by the Investigator to be unsuitable for participation.","ALL","13 Years","EXPANDED_ACCESS","This expanded access protocol is proposed to allow University of California San Francisco (UCSF) patients additional access to 18F-fluorocholine (FCH) Positron Emission Tomography (PET) imaging for localization of parathyroid adenomas.",[20],"Parathyroid Adenomas","AVAILABLE","2025-10-14",{"date":24,"type":25},"2025-10-20","ACTUAL",{"name":27,"class":28},"Thomas Hope","OTHER",{"id":30,"slug":31,"hasResults":11,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":35,"eligibilityCriteria":36,"healthyVolunteers":11,"sex":15,"minAge":37,"maxAge":4,"enrollmentInfo":38,"targetDuration":4,"studyType":41,"phases":4,"briefSummary":42,"conditions":43,"keywords":45,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":57},"100600585","parathyroid-adenoma-detection-with-rubidium-82-imaging-100600585","NCT07099404","Parathyroid Adenoma Detection With Rubidium-82 Imaging","Parathyroid Adenoma Detection With Rubidium Chloride Imaging: A Proof-of-Concept Study","PARAGON","Inclusion Criteria:\n\n1. Age ≥ 18y\n2. Ability to undergo imaging logistics\n3. Ability to provide informed consent\n4. Biochemical evidence of primary hyperparathyroidism\n5. Documented parathyroid adenoma on prior 18F-fluorocholine imaging\n\nExclusion Criteria:\n\n1. Normocalcemic primary hyperparathyroidism\n2. Breastfeeding or pregnancy\n3. Claustrophobia or inability to undergo imaging logistics\n4. Any other history, condition, therapy, or uncontrolled intercurrent illness, which could in the opinion of the investigator affect compliance with study requirements or which would make the participant unsuitable for this study","18 Years",{"count":39,"type":40},20,"ESTIMATED","OBSERVATIONAL","Assess the uptake of rubidium-82 in parathyroid adenomas.",[20,44],"Hyperparathyroidism, Primary",[46],"Parathyroid adenomas, Rubidium-82","NOT_YET_RECRUITING","2025-08-18",{"date":50,"type":25},"2025-08-22",{"date":52,"type":40},"2025-11",{"date":54,"type":40},"2028-09",{"name":56,"class":28},"Matthieu Pelletier-Galarneau, MD MSc",2,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":4,"eligibilityCriteria":64,"healthyVolunteers":11,"sex":15,"minAge":37,"maxAge":4,"enrollmentInfo":65,"targetDuration":4,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":84,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":105},"100580294","high-resolution-pet-ct-specimen-imaging-for-the-perioperative-visualization-of-resection-margins-100580294","NCT06835426","High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins","High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins: an Exploratory Pilot Study","A. Inclusion Criteria:\n\n* able to understand treatment protocol and informed consent form\n* estimated by the investigator to be compliant for study participation\n\n  1\\. Fulfilling all group-specific inclusion criteria:\n* confirmed breast cancer with an indication to undergo breast conserving surgery\n* confirmed prostate cancer with an indication to undergo resective surgeryprostatectomy;\n* confirmed thyroid lesion with an indication to undergo resective surgery;\n* confirmed parathyroid adenoma with an indication to undergo resective surgery;\n* suspected basal cell carcinoma, squamous cell carcinoma or melanoma with an indication to undergo resective surgery;\n* suspected lesion in genitourinary sites (including bladder cancer, renal pelvis and ureter carcinoma, adrenal cortical carcinoma and renal cell carcinoma) with an indication to undergo resective surgery;\n* suspected lesion in the head \\& neck region with an indication to undergo resective surgery;\n* confirmed primary or secondary hepatobiliary cancer with an indication to undergo resective surgery;\n* patients undergoing biopsy after metabolic active lesions were detected on a PET scan.\n* suspected neuro-endocrine malignancies with an indication to undergo resective surgery.\n* suspected brain tumor with an indication to undergo resective surgery.\n* Suspected malignant and benign gastrointestinal lesions with an indication to undergo resective surgery.\n* suspected malignant thoracovascular lesions with an indication to undergo resective surgery\n\nB. Exclusion Criteria:\n\n* general or local contra-indications for resective surgery;\n* in case of FDG-based PET tracers: a blood glucose level over 200 mg\u002FdL on the day of surgery;\n* pregnancy or lactation;\n* participation in other clinical studies with a radiation exposure of more than 1 mSv in the past year.",{"count":66,"type":40},150,"INTERVENTIONAL",[69],"NA","These are patients in whom a benign or malignant tumor was recorded requiring surgery. During that surgery, the surgeon will cut away the tumor as part of the treatment of the disease. In this process, it is important that the tumor is removed correctly and completely. To verify that the correct tissue was completely removed, the tissue is examined microscopically. However, a microscopic analysis takes a relatively long time and the result is not known until a few days after the surgery is completed. If that microscopic analysis should eventually reveal that the tumor was not completely removed, additional treatment is usually necessary. An assessment of the excised tissue during surgery would allow additional tissue to be excised in the same operation if necessary. Thus, in this way, additional treatments can also be avoided. This could lead to shorter treatment time and less emotional strain for the patient, as well as lower costs. To date, however, there are no effective techniques to do this.\n\nPositronEmissionTomography (PET) imaging can be used to image the tumor that needs to be excised. To do this, a tracer must be administered through the blood before the operation. This tracer is a slightly radioactive substance that can be detected by the PET camera even at low concentrations. This technique is already routinely used in the hospital to detect cancer or inflammatory tissue in the body. During this study, however, it's not the intention to look at the tumor while it is still in the patient's body, but rather after it has been cut out of the patient's body by the surgeon. To do this, the piece of tissue cut away will be scanned using a specially designed PET-CT scanner.\n\nThe overall goal of this study is to gain additional knowledge. More specifically, the investigators wish to determine which medical conditions may benefit from high-resolution PET-CT specimen imaging.",[72,73,74,20,75,76,77,78,79,80,81,82,83],"Breast Carcinoma","Prostate Cancer Surgery","Thyroid Cancer","Skin Cancer","Genitourinary Cancer","Head and Neck Cancer","Hepatobiliary Cancers","Metabolic Abnormality","Neuro Endocrine Tumours","Brain Tumours","Gastro Intestinal Cancer","Thoracoscopic Surgery",[85,86,87,88,89,90,91,92,93,94],"resective surgery","perioperative high-resolution PET-CT specimen imaging","breast cancer","Prostate cancer","thyroid cancer","parathyroid cancer","head and neck cancer","neuro-endocrine malignancies","genitourinary malignacies","thoracovascular malignancies","RECRUITING","2025-02-14",{"date":98,"type":25},"2025-02-19",{"date":100,"type":25},"2023-08-06",{"date":102,"type":40},"2027-06-30",{"name":104,"class":28},"Algemeen Ziekenhuis Maria Middelares",1]