[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"paravertebral-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:paravertebral-block":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,51,77,99,123,145,171],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100611543","external-oblique-intercostal-block-eoicb-for-laparoscopic-cholecystectomy-100611543",false,"NCT07241949","External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy","Paravertebral Block or External Oblique Intercostal Block? A Comparative Analysis of Pain and Opioid Consumption After Laparoscopic Cholecystectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia\n* ASA physical status I-III\n* Able to understand the study procedure and provide informed consent\n\nExclusion Criteria:\n\nPatient refusal or inability to provide informed consent\n\nAllergy or contraindication to local anesthetics, tramadol, or study medications\n\nCoagulopathy or current anticoagulant therapy\n\nLocal infection at the planned block injection site\n\nSevere hepatic or renal impairment\n\nChronic opioid use or opioid dependence\n\nNeurological or psychiatric disorders affecting pain perception or communication\n\nPregnancy or breastfeeding\n\nBody mass index (BMI) \\> 35 kg\u002Fm²\n\nConversion to open cholecystectomy during surgery","ALL","18 Years","65 Years",{"count":20,"type":21},147,"ESTIMATED","INTERVENTIONAL",[24],"NA","This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on postoperative pain and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The primary endpoint is total tramadol consumption within 24 hours postoperatively. Secondary outcomes include pain scores, additional analgesic use, incidence of nausea\u002Fvomiting, mobilization time, and length of hospital stay.",[27,28,29,30,31],"Postoperative Pain","Laparoscopic Cholecystectomy","Paravertebral Block","External Oblique Intercostal Plane Block","Patient Controlled Analgesia",[33,34,35,36,37],"Cholecystectomy","Pain","Analgesia","Tramadol","Nerve Block","RECRUITING","2026-06-30",{"date":41,"type":42},"2026-07-02","ACTUAL",{"date":44,"type":42},"2025-12-01",{"date":46,"type":21},"2026-12-05",{"name":48,"class":49},"Cukurova University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":59,"maxAge":18,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":50},"100522406","pectoral-nerve-block-versus-paravertebral-block-in-the-incidence-of-chronic-pain-after-mastectomy-100522406","NCT06082206","Pectoral Nerve Block Versus Paravertebral Block In The Incidence of Chronic Pain After Mastectomy:","Pectoral Nerve Block Versus Paravertebral Block In The Incidence of Chronic Pain After Mastectomy: A Randomized Clinical Trial","Inclusion Criteria:\n\n* ASA grade I, II, or III female patients in the age group of 20-65 years\n* with body mass index (BMI) of 25-35 who were undergoing mastectomy with or without axillary lymph node or sentinel lymph node dissection or partial mastectomy (sparing the skin, areola, and nipple) with axillary lymph node dissection\n\nExclusion Criteria:\n\n* male sex; patient refusal,\n* a life expectancy less than 2 yr;\n* active malignant disease; pregnant or breastfeeding women;\n* bilateral surgery; ipsilateral breast surgery in the past 3 yr;","FEMALE","20 Years",{"count":61,"type":21},90,[24],"Chronic pain after Mastectomy is frequent and an important healthcare priority because of its effect on quality of life. Although the association between the severity of acute pain after surgery and the likelihood of chronic pain is known, their causal relationship has not been clarified. Mastectomy, frequently done for the management of breast cancer, is associated with significant acute postoperative pain and limited shoulder movement.",[29,65,66,67],"Pectoral Nerve Block","Chronic Pain","Mastectomy; Lymphedema","2026-03-06",{"date":70,"type":42},"2026-03-09",{"date":72,"type":42},"2023-11-15",{"date":74,"type":21},"2026-03",{"name":76,"class":49},"Assiut University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":50},"100597831","sensory-anesthesia-achieved-through-different-paravertebral-block-approaches-for-post-op-pain-management-after-vats-lung-resection-100597831","NCT07063602","Sensory Anesthesia Achieved Through Different Paravertebral Block Approaches for Post-Op Pain Management After VATS Lung Resection","Sensory Anesthesia Achieved Through Different Paravertebral Block Approaches for Post-Operative Pain Management After Videothoracoscopic Lung Resection","Inclusion Criteria:\n\n* Patients aged 18 years and older\n* American Society of Anesthesiologists (ASA) score 1-3\n\nExclusion Criteria:\n\n* Contraindication to the paravertebral block (coagulopathy, use of anticoagulants or antiplatelet agents other than aspirin that have not been stopped according to hospital guidelines, thoracoscopic visualization of the paravertebral space expected to be difficult or impossible, anterior spinal surgery with potential discontinuity of the paravertebral space)\n* Epidural analgesia preferred (high risk of thoracotomy, marginal lung function)\n* Surgical criteria: conversion to thoracotomy necessary and thoracic epidural or other form of regional analgesia implemented post-operatively\n* Known allergy to local anesthetics\n* Language barrier, psychiatric, physical or mental condition making pain assessment impossible despite prior education\n* Pregnancy\n* Patient refusal to participate",{"count":61,"type":21},"OBSERVATIONAL","Video-assisted thoracoscopic lung resection (VATS) is a minimally invasive surgical approach frequently used in the treatment of lung cancers. The most commonly used analgesic technique for this surgery is the paravertebral block with a single peroperative injection of local anesthetic. However, a recent study conducted at our institution revealed that this approach provided less relief than expected in some patients. In light of these results, it becomes crucial to distinguish between technical failures (absence of sensitive anesthesia) and the intrinsic limits of the chosen regional analgesia technique (pain originating from an unanesthetized area or pain despite the presence of sensitive anesthesia) in order to better relieve patients.\n\nThis study aims to objectively assess the areas of anesthesia obtained through three methods of paravertebral block to evaluate their respective performance and optimize post-VATS analgesic management.",[88,89,29],"Thoracic Surgery","Video-assisted","2026-02-24",{"date":92,"type":42},"2026-02-27",{"date":94,"type":42},"2025-09-10",{"date":96,"type":21},"2026-09-10",{"name":98,"class":49},"Centre hospitalier de l'Université de Montréal (CHUM)",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":107,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":108,"targetDuration":4,"studyType":22,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":50},"100594607","comparison-of-erector-spina-plan-block-and-thoracic-paravertebral-block-for-perioperative-analgesia-100594607","NCT07021651","COMPARISON OF ERECTOR SPINA PLAN BLOCK AND THORACIC PARAVERTEBRAL BLOCK FOR PERIOPERATIVE ANALGESIA","A Two-Center Randomized Controlled Trial","A Two-Center","Inclusion Criteria:\n\n* Patients who will undergo thoracotomy and are between the ages of 18-65\n* have American Society of Anesthesiologists (ASA) risk classification I-II will be included in the study.\n\nExclusion Criteria:\n\n* Patients who did not agree to participate in the study,\n* had an infection in the application area,\n* had coagulopathy,\n* were morbidly obese (Body mass index (BMI)\\>35),\n* had drug allergy,\n* had chronic pain, long-term opioid use, psychiatric illness history, and required emergency surgery were excluded from the study.",true,{"count":109,"type":21},60,[24],"The primary aim of this study was to compare the postoperative analgesic efficacy of thoracic paravertebral block with erector spinae plane block, which we use in thoracotomy surgeries. Secondary aims were to compare these groups in terms of Riker Agitation-Sedation Scale (RASS) scores, postoperative complications, postoperative opioid consumption, and patient satisfaction.",[29],"NOT_YET_RECRUITING","2025-06-13",{"date":116,"type":42},"2025-06-15",{"date":118,"type":21},"2025-07-10",{"date":120,"type":21},"2025-08-01",{"name":122,"class":49},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":132,"briefSummary":133,"conditions":134,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":141,"leadSponsor":143,"locationsCount":50},"100590993","thoracic-epidural-anesthesia-versus-paravertebral-block-for-awake-thoracotomy-100590993","NCT06974643","Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy","Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy: A Randomized Non-inferiority Trial","Inclusion Criteria:\n\n* Age from 18 to 60 years.\n* Both genders.\n* American Society of Anesthesiologists (ASA) physical status classification II or III.\n* Scheduled for thoracotomy.\n\nExclusion Criteria:\n\n* Poor cardiac function (ejection fraction less than 50%).\n* Patients with bad pulmonary function testing (PFTs). Absolute contraindication to thoracic epidural anesthesia includes patient refusal, allergy to local anesthetics, coagulopathy, active neurologic disorders, skin infection at the insertion site, uncooperative patients, uncontrolled cough, and unfavorable anatomy for thoracic epidural.\n* Thoracic spine disorders require chest wall resection or emergency thoracic surgery.\n* Had a previous thoracotomy (scarring due to prior surgery can limit the effectiveness of paravertebral block, and these patients may have existing chronic pain).","60 Years",{"count":109,"type":21},[24],"This study aims to compare paravertebral block and thoracic epidural in awake thoracotomy.",[135,29,136],"Thoracic Epidural Anesthesia","Awake Thoracotomy","2025-05-15",{"date":139,"type":42},"2025-05-16",{"date":137,"type":42},{"date":142,"type":21},"2025-10-01",{"name":144,"class":49},"Cairo University",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":152,"targetDuration":4,"studyType":22,"phases":154,"briefSummary":155,"conditions":156,"keywords":158,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":4},"100583880","the-effect-of-paravertebral-block-on-recovery-after-cabg-surgery-100583880","NCT06882083","The Effect of Paravertebral Block on Recovery After CABG Surgery","The Effect of Ultrasound-Guided Bilateral Single-Shot Paravertebral Block on Recovery After Coronary Artery Bypass Graft Surgery","Inclusion Criteria:\n\n* Patients aged 18 and older scheduled for elective coronary artery bypass graft surgery with median sternotomy\n\nExclusion Criteria:\n\n* Contraindications to neuroaxial block ( coagulopathy, infection at the injection site, allergy to local anesthetics..)\n* Emergency surgeries\n* severe back deformities\n* Chronic pain\n* refusal to participate\n* CABG without sternotomy",{"count":153,"type":21},120,[24],"The study aims to evaluate the analgesic efficacy of paravertebral block, mobilization speed, respiratory functions, and complication rates in patients who have undergone cardiac surgery and are monitored in the intensive care unit during the postoperative period.",[157,29],"Coronary Artery Bypass Surgery",[159,160,161],"Paravertebral block","Coronary artery bypass surgery","Quality of recovery","2025-03-18",{"date":164,"type":42},"2025-03-20",{"date":166,"type":21},"2025-03-24",{"date":168,"type":21},"2025-08-15",{"name":170,"class":49},"Adiyaman University Research Hospital",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":178,"enrollmentInfo":179,"targetDuration":4,"studyType":22,"phases":181,"briefSummary":182,"conditions":183,"keywords":187,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":195,"leadSponsor":197,"locationsCount":50},"100548877","tpvb-or-spsipb-in-pain-management-after-vats-100548877","NCT06426706","TPVB or SPSIPB in Pain Management After VATS","Paravertebral Block or Serratus Posterior Superior Intercostal Plane Block in Pain Management After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients between the age of 18-80 undergoing video-assisted thoracoscopic surgery\n\nExclusion Criteria:\n\n* Allergy to local anaesthetics Chronic opioid use history Patients with psychiatric disorders Patients who are not open to communication Patients with chronic organ failure Patients that do not give consent Patients that need emergency surgery within the first 24 hours of the initial surgery","80 Years",{"count":180,"type":21},44,[24],"The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic surgery (VATS). The main questions it aims to answer are:\n\nHow will the total perioperative opioid consumption of the patients receiving two different blocks change? How will TPVB and SPSIPB effect the patients' numeric rating scores for pain in the postoperative 24-hour period? How will TPVB and SPSIPB effect the incidence of opioid related side effects?\n\nParticipants will be divided in two groups:\n\nTPVB group will receive a TPVB before the surgery. SPSIPB group will receive a SPSIPB nerve block before the surgery. Researchers will compare the results between the groups to see the postoperative effects concerning opioid consumption as well as the pain scores, respiratory parameters and opioid associated side effects.\n\nThe hypothesis of this study is that participants receiving SPSIPB for VATS will have a less total opioid consumption 24 hours postoperatively.",[184,29,185,186],"Video-assisted Thoracoscopic Surgery","Serratus Posterior Superior Intercostal Plane Block","Regional Anesthesia Morbidity",[188,189,190],"video-assisted thoracoscopic surgery","paravertebral block","serratus posterior superior intercostal plane block","2025-01-02",{"date":193,"type":42},"2025-01-03",{"date":193,"type":21},{"date":196,"type":21},"2025-03-15",{"name":198,"class":49},"Koç University"]