[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parent-child-relations\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parent-child-relations":30},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,36,0,25,[9,47,76,104,134,165,190,216,241,266,302,327,357,382,412,439,470,496,522,552,586,620,648,674,702],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100456946","sensory-optimization-of-the-hospital-environment-100456946",false,"NCT05230199","Sensory Optimization of the Hospital Environment","Multisensory Interventions to Improve Neurodevelopmental Outcomes of Preterm Infants Hospitalized in the Neonatal Intensive Care Unit","SOOTHE","Inclusion Criteria:\n\n* ≤ 32 weeks estimated gestational age (EGA)\n* recruited within the first week of life\n\nExclusion Criteria:\n\n* \\> 32 weeks EGA at birth\n* \\>7 days old\n* become wards of the state\n* have a suspected or confirmed congenital anomaly\n* face a high immediate threat of death, per the opinion of the attending physician.","ALL","1 Day","7 Days",{"count":22,"type":23},215,"ESTIMATED","INTERVENTIONAL",[26],"NA","The long-term goal of this project is to improve the health and well-being of preterm infants and their parents. Although there is evidence to support positive multisensory interventions in the NICU, these interventions are often applied in an inconsistent manner, reducing their benefit. Through a rigorous and scientific process, we have developed a structured multisensory intervention program, titled Supporting and Enhancing NICU Sensory Experiences (SENSE), which includes specific doses and targeted timing of evidence-based interventions such as massage, auditory exposure, rocking, holding, and skin-to-skin care. The interventions are based on the infant's developmental stage and are adapted based on the infant's medical status and behavioral cues. The multisensory interventions are designed to be conducted during each day of NICU hospitalization by the parents, who are educated and supported to provide them. The proposed work aims to determine the effect of multisensory interventions on parent mental health, parent-child interaction, brain activity (amplitude integrated electroencephalography), and infant developmental outcomes through age 2 years, with specific attention to language outcome.",[29,30,31,32,33],"Preterm","Parent-Child Relations","Parents","Development, Infant","Sensory Integration Dysfunction","RECRUITING","2026-06-15",{"date":37,"type":38},"2026-06-17","ACTUAL",{"date":40,"type":38},"2023-05-29",{"date":42,"type":23},"2028-12-31",{"name":44,"class":45},"University of Southern California","OTHER",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":12,"sex":53,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":24,"phases":57,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100536234","parenting-stair-adapting-a-trauma-focused-parenting-intervention-for-military-connected-mothers-and-their-children-100536234","NCT06262178","Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children","Inclusion Criteria:\n\n1. Military-connected mother, defined as a mother who is either a female service member or veteran or female spouse of a service member or veteran;\n2. Has a child aged 2-10;\n3. Legal guardian of index child with legal and physical custody;\n4. Lifetime trauma exposure (Life Events Checklist (LEC-5); Adverse Childhood Experiences Questionnaire (ACE-Q));\n5. Screen positive for PTSD (defined as a PCL-5 score ≥32 or meeting ≥3 out of 4 DSM-5 symptom criteria \\[B, C, D, E\\] on the PCL-5), and\u002For depression (PHQ-9 score ≥8), and\u002For low parenting self-efficacy (PSOC score \\\u003C59);\n6. Able to speak and understand English or Spanish;\n7. Eligible to receive services at a Steven A. Cohen Military Family Clinic at Endeavors.\n\nExclusion Criteria:\n\n1. High risk for suicide (Ask Suicide-Screening Questions (ASQ));\n2. Current psychotic symptoms (DSM-5-TR Self-Rated Level 1 Cross-Cutting Symptom Measure Domain VII);\n3. Disability affecting communication, such as deafness;\n4. Index child with severe developmental disability;\n5. Severe substance or alcohol use (The Alcohol, Smoking and Substance Involvement Screening Test - Lite (ASSIST-Lite); Cannabis Use Disorder Identification Test-Short Form (CUDIT-SF)).","FEMALE","18 Years",{"count":56,"type":23},120,[26],"The goal of this study is to assess Parenting STAIR Modular (PSTAIR-M), a promising and innovative intervention for military-connected mothers (MCM) who have experienced trauma and their young children (ages 2-10). PSTAIR-M aims to help mothers manage the strong feelings that sometimes happen after experiencing something scary or stressful, as well as to better connect with their children and manage their behavior effectively.\n\nThe main questions the study aims to answer are: 1) Does PSTAIR-M reduce maternal PTSD and\u002For depression symptoms?, and 2) Does PSTAIR-M improve parental functioning?\n\nResearchers will compare PSTAIR-M to treatment as usual (TAU) - other EBTs offered at participating study sites - to determine if PSTAIR-M is more effective in improving mental health and parenting.\n\nParticipants will: 1) attend 12-16 weekly, 1-hour online treatment sessions with their assigned clinicians, 2) complete three 1-hour online assessments administered by research staff, 3) engage with their child in three 15-30-minute online, observed play sessions, 4) have assessments and observed play sessions audio and video recorded.\n\nParticipants may also be invited to participate in an optional, 30-minute online one-on-one qualitative interview, which would be audio and video recorded and would cover participants' experiences with the intervention, the clinic sites, and their providers.",[60,61,30],"PTSD","Depression",[60,61,63,64,65,30,66],"STAIR","PC-CARE","Parenting","Military Family","2026-06-11",{"date":35,"type":38},{"date":70,"type":38},"2025-07-21",{"date":72,"type":23},"2027-09-30",{"name":74,"class":45},"New York University",3,{"id":77,"slug":78,"hasResults":12,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":12,"sex":18,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":24,"phases":87,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":46},"100590141","examining-whether-project-support-works-100590141","NCT06963554","Examining Whether Project Support Works","Randomized Controlled Trial of Project Support","Inclusion Criteria:\n\n* Family is seeking trauma-focused services for their child;\n* Child is between 6 - 13 years old;\n* Caregiver agreed to be contacted for volunteer research opportunities;\n* Caregiver and child can communicate in English or Spanish;\n* Child has been living with caregiver for the last 6 months or longer;\n* Family is able to participate in services delivered via telehealth.\n\nExclusion Criteria:\n\n* Child or caregiver has a diagnosis that would impair their ability to participate in or benefit from services (e.g., traumatic brain injury, developmental disability, psychosis);\n* Child is in Foster Care or Department of Social Services custody;\n* The caregiver is unwilling or unable to give informed consent and\u002For the child is unwilling and unable to give assent.","6 Years","13 Years",{"count":86,"type":23},100,[26],"This study will involve a randomized, controlled trial with two parallel groups, Project Support and a treatment as usual control group. Families with a child on the waitlist for trauma-focused services will be invited to participate. Participation involves completing a baseline assessment of family functioning and trauma characteristics. Participants will then be randomized to either Project Support or the treatment as usual control group. All participants will be invited to complete the post-test assessment 4-6 weeks after the baseline assessment, prior to beginning trauma-focused services.",[30,90,91],"Parenting Self Efficacy","Child Mental Health",[93,94],"Child trauma","Non-offending caregiver","2026-06-08",{"date":97,"type":38},"2026-06-09",{"date":99,"type":38},"2025-11-04",{"date":101,"type":23},"2028-03-31",{"name":103,"class":45},"Medical University of South Carolina",{"id":105,"slug":106,"hasResults":12,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":53,"minAge":54,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":24,"phases":114,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":133},"100642971","postpartum-intervention-for-mothers-with-opioid-use-disorders-r33-100642971","NCT07632053","Postpartum Intervention for Mothers With Opioid Use Disorders (R33)","PIMO","Inclusion Criteria:\n\n* mothers with diagnosis of Opioid Use Disorder (OUD); and\u002For receiving medication assisted treatment (such as buprenorphine or methadone)\n* with a child aged 5 or less\n* able to read, hear and understand English adequately enough to provide informed consent\n\nExclusion Criteria:\n\n* require immediate clinical care for suicidal\u002Fhomicidal risk or psychosis;\n* For magnetic resonance imaging (MRI) of the brain, potential participants will be excluded if they: (1) have ferromagnetic metal in their heads (2) have severe claustrophobia that prevents participation in the neuroimaging (3) have serious neurological condition that could interfere with neuroimaging, including a brain tumor, multiple sclerosis or significant head trauma","50 Years",{"count":113,"type":23},80,[26],"Having met the milestones of the R61, this R33 is a 2-site, 2-group, pre\u002Fpost RCT of mothers with OUD (n=\\~80\u002Fgroup). We will test whether the beneficial pre-post changes in OUD mothers randomized to vMP exceed those of mothers assigned to Enhanced Usual Care (EUC) and via changes in Maternal Brain Neurocircuits.",[117,30],"Opioid Use Disorder",[119,120,121,122,123,124],"parenting intervention","opioid use disorder","parental stress","maternal brain","evoked response potentials","brain fMRI","2026-06-05",{"date":97,"type":38},{"date":128,"type":38},"2025-07-01",{"date":130,"type":23},"2028-07",{"name":132,"class":45},"Stony Brook University",2,{"id":135,"slug":136,"hasResults":12,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":24,"phases":144,"briefSummary":145,"conditions":146,"keywords":148,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":46},"100543158","the-playful-learning-in-infancy-program-100543158","NCT06352229","The Playful Learning in Infancy Program","The Playful Learning in Infancy Program (PLIP): A Pilot Feasibility Study of an Universal Educational Parenting Program Using a Parallel Group Design","PLIP","Inclusion Criteria:\n\n* Residence address in the Danish municipalities of Hvidovre or Billund\n* Residence address with child or legal custody of the child\n* Child is between 1-7 months old\n* Understands Danish or English\n\nExclusion Criteria:\n\n* Parental age under the age of 18 when the child is born\n* Multiple pregnancy",{"count":143,"type":23},2327,[26],"In the Playful Learning in Infancy Program, parents receive research-based educational guidance on playful interactions with their infants aged 0-1 year. They learn to recognize their infants' cues indicating readiness to engage in play and they are introduced to specific, developmentally appropriate activities for interactive engagement. The guidance is delivered to parents during routine home visits by public health visitors.\n\nThe aims of the Playful Learning in Infancy Program are to 1) promote playful interactions between infants and parents, parental attitudes towards play, and infant socioemotional development; 2) enhance the language and knowledge of playful learning in infancy among frontline staff; and 3) evaluate the Playful Learning in Infancy Program for potential testing in a future large-scale RCT study.\n\nEvaluation is based on a parallel group study design, with half of the participants receiving care as usual and half of the participants receiving care as usual along with the Playful Learning in Infancy Program.",[30,147],"Infant Development",[149,150,151,152,153,154,155],"Universal intervention","Playful Learning","Infant","Parental competence","Socioemotional","Public health visitors","Prevention","2026-05-20",{"date":158,"type":38},"2026-05-26",{"date":160,"type":38},"2023-06-01",{"date":162,"type":23},"2026-11-30",{"name":164,"class":45},"University of Copenhagen",{"id":166,"slug":167,"hasResults":12,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":172,"sex":18,"minAge":173,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":24,"phases":177,"briefSummary":178,"conditions":179,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":133},"100457173","child-adult-relationship-enhancement-in-primary-care-pricare--criando-nios-con-cario-cario-100457173","NCT05233150","Child-Adult Relationship Enhancement in Primary Care (PriCARE) \u002F Criando Niños Con CARIÑO (CARIÑO)","Child-Adult Relationship Enhancement in Primary Care: Supporting Parents and Children","Inclusion Criteria:\n\n* Caregiver is age 18 years or older\n* Caregiver is English or Spanish Speaking\n* Caregiver is legal guardian of child subject\n* Caregiver provides informed consent\n* Caregiver is available to attend scheduled times of PriCARE\u002FCARIÑO groups\n* Caregiver has cellular phone with text messaging capacity\n* Caregiver has appropriate technological tools and access to participate in virtual intervention\n* Child is between 18 months and 6 years old\n* Child receives care at participating primary care center\n* Child has Medicaid\u002FChildren's Health Insurance Program (CHIP)\u002Fno insurance\n* Child lives in North Carolina or Philadelphia\n\nExclusion Criteria:\n\n* Caregiver or another caregiver in the household has previously participated in PriCARE\u002FCARIÑO\n* Child has a cognitive functioning below 2-year-old level, as determined by the screening questions and\u002For the referring clinician\n* Child has a diagnosis of autism\n* Child is receiving individual behavioral health treatment or medication for a behavioral health problem",true,"18 Months","99 Years",{"count":176,"type":23},1932,[26],"The purpose of this study is evaluate the effectiveness of PriCARE\u002FCARIÑO to reduce child maltreatment, improve parent-child interactions, and reduce harsh\u002Fneglectful parenting, parent stress, and child behaviors.",[30,180],"Child Maltreatment","2026-04-29",{"date":183,"type":38},"2026-05-01",{"date":185,"type":38},"2022-05-18",{"date":187,"type":23},"2027-07-01",{"name":189,"class":45},"University of North Carolina, Chapel Hill",{"id":191,"slug":192,"hasResults":12,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":12,"sex":18,"minAge":84,"maxAge":197,"enrollmentInfo":198,"targetDuration":4,"studyType":24,"phases":200,"briefSummary":201,"conditions":202,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":46},"100365290","dyad-plus-effectivenessfeasibility-100365290","NCT04036331","Dyad Plus Effectiveness\u002FFeasibility","Effectiveness\u002FFeasibility of A Coordinated Parent\u002FChild Dyad Weight Loss Intervention:","Inclusion Criteria:\n\n* Eligible for enrollment in Brenner FIT and\u002For By Design Essentials\n* Caregiver who lives in the house with a BMI \\> 30\n* No contraindication for physical activity or caloric restriction\n* Must be able to read and write English\n\nExclusion Criteria:\n\n* BMI \\\u003C 30\n* Contraindication for physical activity or caloric restriction\n* Cannot read or write English","65 Years",{"count":199,"type":23},90,[26],"The purpose of this research is to determine the effectiveness of a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, joint problem solving, and social support to increase physical activity, healthy eating, and weight loss. Participants of the Brenner FIT (Families In Training) pediatric weight management program and their parent\u002Fguardian will co-enroll in weight loss programs. Parents\u002Fguardians will receive the components of By Design Essentials.",[203,204,205,30,206],"Weight Loss","Pediatric Obesity","Overweight Adolescents","Family and Household","2026-04-27",{"date":209,"type":38},"2026-04-28",{"date":211,"type":38},"2021-07-30",{"date":213,"type":23},"2026-07",{"name":215,"class":45},"Wake Forest University Health Sciences",{"id":217,"slug":218,"hasResults":12,"nctId":219,"briefTitle":220,"officialTitle":220,"acronym":4,"eligibilityCriteria":221,"healthyVolunteers":172,"sex":18,"minAge":222,"maxAge":223,"enrollmentInfo":224,"targetDuration":4,"studyType":24,"phases":226,"briefSummary":227,"conditions":228,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":46},"100493532","an-evidence-based-family-support-program-for-parents-and-children-in-palestine-a-theory-based-intervention-100493532","NCT05706376","An Evidence-based Family Support Program for Parents and Children in Palestine: A Theory-based Intervention","Inclusion Criteria:\n\n* a willing adolescent between the ages of 13 and 16\n* assuming a two-parent family, a mother and father willing to participate\n* within the service area of implementing organizations\n\nExclusion Criteria:\n\n* Families with individuals with significant mental or physical impairments precluding their ability to participate in groups","12 Years","75 Years",{"count":225,"type":23},900,[26],"Few evidence-based programs exist to support children and families affected by sociopolitical conflict, despite documented evidence of their heightened risk for emotional and behavioral adjustment problems associated with exposure to conflict and violence at multiple levels of the social ecology (e.g., political, community, and family). Thus, a critical need exists for an evidence-based program to ameliorate the impact of political violence on the overall well-being of children and families. The current study will conduct a rigorous evaluation of a theoretically-driven, family-based intervention program in Palestine, including both the West Bank and Gaza. Firmly grounded in the cultural context of Palestine but with broad implications for individuals exposed to sociopolitical violence, the long-term goal of this project is to provide a family-focused intervention program (Promoting Positive Family Futures; PPFF) that may facilitate individuals' sense of safety and support in the context of chronic adversity. The objective is to evaluate this intervention program in the context of a randomized clinical trial (RCT) in the West Bank and Gaza (N=300). The central hypothesis is that the program will have direct positive effects on family conflict, parent psychopathology and parental security in the family as well as on adolescent emotional security in the family, with cascading effects on adolescent adjustment. Consistent with family systems theory, we further hypothesize that treatment effects on parents will mediate on the effects of the treatment on adolescent adjustment. The rationale is that bolstering resilience in family systems is a key approach to promoting positive functioning in families exposed to chronic violence. The hypothesis will be evaluated with three specific aims: 1) evaluate the efficacy of an evidence-based family support program; 2) examine process models of treatment change, and 3) examine interrelations between parent and child functioning. To achieve these aims, the study will be an RCT employing a longitudinal design (N=300) with multi-method assessments at baseline (T1), post-test (T2), 6-month follow-up (T3) and 12-month follow-up (T4). Families included in the study will be evenly divided between the West Bank (n=150) and Gaza Strip (n=150). Families will be randomized into the intervention condition (PPFF) or treatment as usual (TAU). Each territory will have an implementing partner, and implementing partners and investigators will work together to ensure the study procedures are implemented in parallel across sites. Data collection will be conducted by trained research staff from a third-party survey and policy research organization. The proposal seeks to shift current research and clinical paradigms in these contexts by employing novel theoretical concepts, approaches, and methodologies. The contribution will be significant by 1) further developing new directions for empirically-based interventions in these high-risk contexts, and 2) advancing a relatively brief, cost-effective program that can be readily implemented to help children and families exposed to continuing conflict in Palestine, with the potential to be brought to scale in other contexts.",[229,230,30,231],"Adolescent","Psychopathology","Violence","2026-04-20",{"date":234,"type":38},"2026-04-23",{"date":236,"type":38},"2023-09-19",{"date":238,"type":23},"2027-07-31",{"name":240,"class":45},"University of Notre Dame",{"id":242,"slug":243,"hasResults":12,"nctId":244,"briefTitle":245,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":172,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":247,"targetDuration":4,"studyType":24,"phases":249,"briefSummary":250,"conditions":251,"keywords":253,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":46},"100524518","delivering-evidence-based-parenting-services-to-families-in-child-welfare-using-telehealth-100524518","NCT06109766","Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth","Inclusion Criteria: Birth parents will be eligible if:\n\n1. they are listed in the official DCYF child welfare database as having an open CPS or FAR intake and a child listed in the case file who is between 6-12 months old,\n2. they speak English,\n3. they are not currently experiencing an acute hospitalization or incarceration,\n4. they have the technological capacity to engage in telehealth, and\n5. they have not had PFR in the past.\n\nExclusion Criteria: Parents will not be eligible if\n\n1. they are experiencing an acute crisis (e.g., hospitalization, incarceration),\n2. they don't have stable enough housing to be able to have home visits,\n3. they don't have reliable access to internet or cell service and\u002For a device with a microphone and camera,\n4. previously received the Promoting First Relationships ® intervention or Child Parent Psychotherapy (CPP).",{"count":248,"type":23},357,[26],"The goal of this randomized controlled trial is to compare Promoting First Relationships - Home Visit (PFR-HV) to Promoting First Relationships - Telehealth (PFR-T) among parents of 6-12 month olds in the child welfare system. The main questions it aims to answer are:\n\n* Is PFR-T effective relative to PFR-HV and Usual Care with respect to observed parent sensitive and responsive care, parent knowledge of child social and emotional development, and child externalizing behavior?\n* Is PFR-T effective relative to PFR-HV and Usual Care with respect to child out-of-home placement in foster care relative to the control group?\n* How does PFR-T compare in a benefit-cost analysis to the cost-effectiveness relative to PFR-HV and Usual Care?\n* Are eligible families impacted by the lack of technology and Wi-Fi\u002Fcellular data to engage in PFR-T?\n* How does provider adherence and fidelity in delivery of PFR-T compare to adherence and fidelity of PFR-HV?\n\nWhat will participants be asked to do?\n\n1. Participants will be asked to agree to randomization, resulting in their placement in one of three groups: PFR-HV, PFR-T, or the control group.\n2. Participants will be asked to participate in three virtual research visits, over the course of approximately 12 months (families could be finished as early as 9 months, however in our experience, intervention sessions and research visits often need to be rescheduled, delaying completion of the study). The research visits take approximately 80 minutes, and families will be paid $75 for each visit they participate in.\n3. During the research visit, the families will be asked to participate in videotaped research activities involving parent-child play and interaction. Parents will be asked to answer questions regarding their background, feelings, parenting opinions, and stress.\n4. Families randomized to the PFR-HV intervention are asked to participate in a 10 week in home parenting program which includes videotaped caregiver-child interactions and feedback.\n5. Families randomized to the PFR-T intervention are asked to participate in a 10-week parenting program that will occur over Zoom, which will include videotaped caregiver-child interactions and feedback.\n6. Families randomized to the control group will be emailed a resource packet with some information about services or programs that might be helpful for them.",[65,30,252,180],"Child Behavior",[254,255,256],"Telehealth","Fidelity","Cost-Benefit Analysis","2026-03-11",{"date":259,"type":38},"2026-03-16",{"date":261,"type":38},"2023-10-12",{"date":263,"type":23},"2028-04-12",{"name":265,"class":45},"University of Washington",{"id":267,"slug":268,"hasResults":12,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":272,"eligibilityCriteria":273,"healthyVolunteers":172,"sex":18,"minAge":274,"maxAge":275,"enrollmentInfo":276,"targetDuration":4,"studyType":24,"phases":278,"briefSummary":279,"conditions":280,"keywords":286,"overallStatus":291,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":295,"completionDateStruct":297,"leadSponsor":299,"locationsCount":46},"100628470","talk-parenting-education-program-ii-100628470","NCT07462052","Talk Parenting Education Program II","Utilizing Smart Speaker Technology to Deliver Parenting Education Support to Parents of Young Children","TP2","Inclusion Criteria:\n\n* Referred by a participating agency\n* Child 3-5 years old who lives with the parent at least half time\n* The primary parent in the home (typically the mother but not always)\n* Speaks English\n* Has access to a computer, tablet, or mobile phone at home\n* Access to high-speed internet at home is desired but not required.\n\nThe project will cover internet costs for a small number of participants if needed. The participating agencies all serve families who are low-income and\u002For experiencing economic hardship, stressful family relationships, children's behavior problems, or household instability; thus referred families will be experiencing one or more of these risk factors for an at-risk family environment.\n\nExclusion Criteria:\n\n* Families of target-age children with a developmental disability severe enough that the child cannot speak or follow simple directions will be excluded\n* Families of target-age children whose needs are beyond the scope of Talk Parenting will be excluded","3 Years","90 Years",{"count":277,"type":23},184,[26],"The goal of this clinical trial is to learn whether Talk Parenting, a voice-based program delivered through an Amazon Echo Dot (Alexa), can help parents and caregivers of children ages 3-5 years improve challenging bedtime and morning routines. The main questions it aims to answer are:\n\nDoes using Talk Parenting improve families' bedtime and morning experiences and children's sleep\u002Fwake habits?\n\nDoes using Talk Parenting improve parents' routine-related parenting practices and confidence, strengthen the parent-child relationship, and reduce children's behavior problems and parents' stress?\n\nResearchers will compare families who receive Talk Parenting right away to families who wait 6 weeks to receive the program (a waitlist control group receiving usual services during the wait).\n\nParticipants will:\n\nComplete online questionnaires at the start of the study and again about 6 weeks later (and a follow-up questionnaire later in the study).\n\nReceive a pre-configured Amazon Echo Dot (to keep) and instructions to use Talk Parenting routines at home, including a bedtime routine, a brief calming routine, and a morning routine (enabled after the first 2 weeks).",[281,282,283,252,284,285,30],"Parenting Practices","Self Efficacy","Stress","Emotional Adjustment","Sleep Problem",[287,288,289,290],"Feasibility","Satisfaction","Usability","Efficacy","NOT_YET_RECRUITING","2026-03-06",{"date":294,"type":38},"2026-03-10",{"date":296,"type":23},"2026-07-01",{"date":298,"type":23},"2028-04-01",{"name":300,"class":301},"Oregon Research Behavioral Intervention Strategies, Inc.","INDUSTRY",{"id":303,"slug":304,"hasResults":12,"nctId":305,"briefTitle":306,"officialTitle":307,"acronym":4,"eligibilityCriteria":308,"healthyVolunteers":172,"sex":18,"minAge":83,"maxAge":4,"enrollmentInfo":309,"targetDuration":4,"studyType":24,"phases":311,"briefSummary":312,"conditions":313,"keywords":315,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":323,"leadSponsor":325,"locationsCount":133},"100606054","relationship-enhancement-digital-game-100606054","NCT07170553","Relationship Enhancement Digital Game","Digital Game Intervention for Relationship Enhancement Among Parent Child Dyads","Inclusion Criteria:\n\n* Caregiver-child dyads.\n\nExclusion Criteria:\n\n* Participant is not part of a caregiver- child dyad.",{"count":310,"type":23},30,[26],"The purpose of this study is to test a new digital game. Specifically, this study will aim to evaluate a digital game prototype designed to facilitate playful interactions between parents and children. The prototype will incorporate activities grounded in relationship enhancement principles. Additionally, this study will check how well using digital tools helps build strong connections, makes people get along better, and boosts parents' confidence and parenting skills.",[30,65,314],"Attachment Disorder",[316,317],"Digital Intervention","Attachment Based","2026-02-27",{"date":320,"type":38},"2026-03-03",{"date":322,"type":23},"2026-06",{"date":324,"type":23},"2027-04-30",{"name":326,"class":45},"University of Miami",{"id":328,"slug":329,"hasResults":12,"nctId":330,"briefTitle":331,"officialTitle":332,"acronym":4,"eligibilityCriteria":333,"healthyVolunteers":172,"sex":18,"minAge":54,"maxAge":334,"enrollmentInfo":335,"targetDuration":4,"studyType":336,"phases":4,"briefSummary":337,"conditions":338,"keywords":341,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":348,"lastUpdatePostDateStruct":349,"startDateStruct":351,"completionDateStruct":353,"leadSponsor":355,"locationsCount":133},"100579719","potential-benefits-of-parent-child-interaction-therapy-pcit-100579719","NCT06827951","Potential Benefits of Parent Child Interaction Therapy (PCIT)","A Mixed-Methods Approach Utilizing Self-Report Scales and Oxytocin Levels to Determine the Potential Benefits of Parent Child Interaction Therapy (PCIT)","Inclusion Criteria:\n\n* Parents of children aged 2-7 years old who are eligible for Parent-Child Interaction Therapy (PCIT) based on behavioral concerns.\n* The primary caregiver of the child and be actively involved in the child's daily care.\n* Willing to attend all PCIT sessions and complete pre-, mid- and post-intervention assessments.\n* Fluent in English to ensure comprehension of the intervention and assessment materials.\n\nExclusion Criteria:\n\n* Parents with diagnosed severe mental health disorders (e.g., schizophrenia, bipolar disorder) that may interfere with participation in PCIT.\n* Children with conditions that require interventions other than PCIT (e.g., severe developmental disabilities).\n* Parents who have previously participated in PCIT are excluded to avoid confounding results.","89 Years",{"count":113,"type":23},"OBSERVATIONAL","The goal of this study is to explore possible benefits of Parent-Child Interaction Therapy (PCIT). The main goals of the study are:\n\n* To investigate whether pre-survey measures of autonomic reactivity relate to the overall functioning of participants.\n* To examine the effects of PCIT To identify individual characteristics that influence the effects of PCIT.\n\nParticipants will:\n\n* complete 5 online surveys (1x pre-PCIT, 3x during PCIT, and 1x post-PCIT)\n* complete the PCIT program",[339,340,61,30],"Autonomic Dysregulation","Anxiety",[342,343,344,345,346,347],"Polyvagal Theory","Adversity","Parent-Child Interaction Therapy","Attachment","Autonomic Reactivity","Oxytocin","2026-02-09",{"date":350,"type":38},"2026-02-12",{"date":352,"type":38},"2025-02-14",{"date":354,"type":23},"2026-06-01",{"name":356,"class":45},"University of Florida",{"id":358,"slug":359,"hasResults":12,"nctId":360,"briefTitle":361,"officialTitle":362,"acronym":363,"eligibilityCriteria":364,"healthyVolunteers":172,"sex":18,"minAge":274,"maxAge":365,"enrollmentInfo":366,"targetDuration":4,"studyType":24,"phases":367,"briefSummary":368,"conditions":369,"keywords":371,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":375,"lastUpdatePostDateStruct":376,"startDateStruct":377,"completionDateStruct":379,"leadSponsor":380,"locationsCount":46},"100575054","i-interact-preterm-parenting-100575054","NCT06767293","I-InTERACT Preterm Parenting","I-InTERACT Preterm Parenting Randomized Controlled Trial","I2P-RCT","Inclusion Criteria:\n\n* Born at \\\u003C 32 weeks gestational age.\n* Total T score of \\> 55 on the Child Behavior Checklist Total or Externalizing Behavior Scales OR Total T score of \\> 55 on the Eyberg Child Behavior Inventory total problem- or total intensity-scale.\n* English is the primary spoken language in the home.\n\nExclusion Criteria:\n\n* Is not 18 years or older.\n* Participant will be excluded from the study if the child does not reside with the caregiver at least half-time; the caregiving situation is not stable (i.e., there must be no scheduled custody hearings).\n* English is not the primary language spoken in the home.\n* Caregivers with a psychiatric hospitalization in the past year.","8 Years",{"count":199,"type":23},[26],"Many children born very preterm experience behavior problems, and existing resources for parenting these children are lacking. A pilot trial established the effectiveness of a preterm parenting intervention, I-Interact Preterm (I2P). This study proposes a three-arm randomized controlled trial (RCT) comparing the established seven-session I2P program, a microlearning delivery mode (I2P-Micro), and an internet resource comparison group (IRC). Outcomes will be assessed at pretreatment, post-treatment (12 weeks later), and at an extended follow-up six months post-randomization. These outcomes include parenting behaviors, child behavior problems, and parent distress. It is anticipated that both I2P and I2P-Micro will result in significant improvements relative to the IRC condition, with greater utilization expected in the I2P-Micro group.",[370,29,30,65],"Child Behavior Problem",[372,373,374],"telehealth","online learning","microlearning","2026-02-05",{"date":348,"type":38},{"date":378,"type":38},"2024-11-27",{"date":72,"type":23},{"name":381,"class":45},"Children's Hospital Medical Center, Cincinnati",{"id":383,"slug":384,"hasResults":12,"nctId":385,"briefTitle":386,"officialTitle":387,"acronym":388,"eligibilityCriteria":389,"healthyVolunteers":172,"sex":18,"minAge":390,"maxAge":174,"enrollmentInfo":391,"targetDuration":4,"studyType":24,"phases":393,"briefSummary":394,"conditions":395,"keywords":396,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":403,"lastUpdatePostDateStruct":404,"startDateStruct":406,"completionDateStruct":408,"leadSponsor":410,"locationsCount":46},"100571815","parent-encouragement-and-coaching-of-happiness-in-youth-100571815","NCT06725160","Parent Encouragement And Coaching of Happiness in Youth","Maternal Positive Affect Socialization and Child Neural Reward Response","PEACHY","Inclusion Criteria for Mothers:\n\n* Birth mother (biologically female, any gender)\n* Providing regular care for participating child (i.e., at least 50% of time)\n* Elevated, clinically significant levels of depression (16 or higher on CES-D)\n* Aged 18+\n\nExclusion Criteria for Mothers:\n\n* Lifetime history of a bipolar disorder\n* Lifetime history of a psychotic disorder\n\nInclusion Criteria for Participating Child:\n\n-Aged 4-6 years\n\nExclusion Criteria for Participating Child:\n\n* T-score greater than 63 on the internalizing or externalizing composites of the CBCL\n* Lifetime history of a psychiatric illness\n* Lifetime history of neurodevelopmental disorder\n* Lifetime history of neurological disorder","4 Years",{"count":392,"type":23},180,[26],"The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are:\n\nAim 1. Characterize child neural reward response and its relation to maternal socialization of positive emotions at baseline in healthy young children.\n\nAim 2. Evaluate how coaching-related changes in maternal socialization of positive emotion expression contribute to increases in child neural reward response over time.\n\nAim 3. Examine how maternal socialization of positive emotion expression contributes to increases in child neural reward response in the moment.\n\nParticipating mother-child dyads will be randomized to either 3 sessions of parent coaching of child positive affect or 3 sessions of a general parenting support intervention and neural response to reward and affective behavior will be examined pre and post intervention.",[61,30],[397,398,399,400,401,402],"depression","reward","neural","behavior","parent","early childhood","2026-01-26",{"date":405,"type":38},"2026-01-28",{"date":407,"type":38},"2025-10-28",{"date":409,"type":23},"2029-02-01",{"name":411,"class":45},"University of Pittsburgh",{"id":413,"slug":414,"hasResults":12,"nctId":415,"briefTitle":416,"officialTitle":416,"acronym":4,"eligibilityCriteria":417,"healthyVolunteers":12,"sex":18,"minAge":418,"maxAge":4,"enrollmentInfo":419,"targetDuration":4,"studyType":24,"phases":421,"briefSummary":423,"conditions":424,"keywords":426,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":430,"lastUpdatePostDateStruct":431,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":437,"locationsCount":133},"100498156","phase-3-affirmative-family-and-individual-psychotherapy-for-sexual-and-gender-minority-adults-and-their-nonaccepting-parents-100498156","NCT05766592","Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents","Inclusion Criteria:\n\n* be 20 and older\n* be fluent in English\n* self-identify as lesbian, bisexual, queer, pansexual, or other non-heterosexual identity\n* currently experience elevated depressive or anxiety symptoms (screened initially using a cutoff of ≥ 2.5 on the Brief Symptom Inventory-4 and further confirmed by the BDI and BAI).\n* report at least moderate levels of parental rejection or low levels of parental acceptance, as measured using the PARSOS.\n* have at least one rejecting\u002Fnonaccepting parent that agrees to participate in the therapy.\n* live in New York State, Pennsylvania, Connecticut, or Israel.\n\nExclusion Criteria:\n\n* report current mental health treatment ≥1 day\u002Fmonth (except for medication management ≤1 day\u002Fweek)\n* report beginning a new medication within the past 30 days\n* exhibit active psychosis or active mania, as assessed by the SCID-Psych Screen.\n* exhibit active suicidality or active homicidality, as assessed by the SIDAS\n* be currently legally mandated to attend treatment\n* demonstrate gross cognitive impairment, as assessed with the Telephone Interview for Cognitive Status\n* do not have a parent willing to participate","20 Years",{"count":420,"type":23},124,[422],"PHASE3","The purpose of this study is to assess the efficacy of an LGBTQ-affirmative individual cognitive behavioral psychotherapy (CBT) and LGBTQ-affirmative family therapy (attachment-based family therapy for sexual and gender minority young adults; ABFT-SGM) delivered via telehealth to a sample of sexual and gender minority adults with nonaccepting parent(s) in New York, Pennsylvania, Connecticut, and Israel. The investigators will assess whether both treatments are associated with significant decreases in depressive and anxiety symptoms. The investigators will also assess whether and how each treatment achieves reductions in mental health symptoms through specific mechanisms (e.g., rejection sensitivity, internalized stigma, emotion dysregulation, parental rejection and acceptance).",[425,30],"Mental Health Issue",[427,428,429],"LGBTQ","Cognitive Behavioral Therapy","Attachment-Based Family Therapy","2026-01-12",{"date":432,"type":38},"2026-01-13",{"date":434,"type":38},"2024-08-13",{"date":436,"type":23},"2027-06-30",{"name":438,"class":45},"Yale University",{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":446,"targetDuration":4,"studyType":24,"phases":447,"briefSummary":448,"conditions":449,"keywords":454,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":461,"lastUpdatePostDateStruct":462,"startDateStruct":464,"completionDateStruct":466,"leadSponsor":468,"locationsCount":46},"100619222","parental-support-intervention-in-an-advanced-oncological-context-100619222","NCT07341815","Parental Support Intervention in an Advanced Oncological Context","Efficacy of a Parental Support Intervention to Improve Communication of Advanced Cancer Patients With Adolescents and Young Adults","Inclusion Criteria:\n\n* Metastatic cancer, recurrence of cancer or certain types of hematological cancer (chronic disease, acute leukemia, multiple myeloma or lymphoma recurrence)\n* Have at least one child aged between 10 and 25 years\n* Wish to benefit from a psychological intervention about communication with their children about cancer or its consequences\n* Able to read and speak French\n* Accept to give their written informed consent\n\nExclusion Criteria:\n\n* Severe neurological disorder\n* Severe psychiatric disorder\n* (Pre-)terminal phase of cancer disease",{"count":56,"type":23},[26],"This prospective, two-arm randomized trial compares a psycho-educational program to a psycho-educational and experiential program for parents with advanced cancer. These two interventions aim to support parent-child communication about cancer, but we hypothesize that the combined intervention will be more effective for all studied communication variables.",[450,451,452,30,65,453],"Metastatic Cancer","Cancer Recurrence","Hematological Cancer","Communication",[455,456,457,458,459,460],"Parental cancer","Parent-child communication","Parenting intervention","Advanced cancer","Adolescent Young Adult (AYA)","Uncertainty","2026-01-07",{"date":463,"type":38},"2026-01-14",{"date":465,"type":38},"2022-05-27",{"date":467,"type":23},"2026-12",{"name":469,"class":45},"Université Libre de Bruxelles",{"id":471,"slug":472,"hasResults":12,"nctId":473,"briefTitle":474,"officialTitle":475,"acronym":476,"eligibilityCriteria":477,"healthyVolunteers":12,"sex":18,"minAge":478,"maxAge":4,"enrollmentInfo":479,"targetDuration":4,"studyType":24,"phases":481,"briefSummary":483,"conditions":484,"keywords":485,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":461,"lastUpdatePostDateStruct":488,"startDateStruct":490,"completionDateStruct":492,"leadSponsor":494,"locationsCount":495},"100509931","phase-1-supporting-parents-in-affirming-their-childrens-experiences-of-stigma-100509931","NCT05919849","Supporting Parents in Affirming Their Children's Experiences of Stigma","Development and Initial Trial of Two Brief Interventions to Support Parents in Affirming Their Children's Experiences of Sexuality and Gender","SPACES","Inclusion Criteria:\n\n1. Parents are eligible if they meet the following criteria:\n\n   1. Be a parent, grandparent, or any other family member who considers themselves a guardian of an SGMY between 15-29 years old,\n   2. Live in the Southeast United States (Louisiana, Mississippi, Alabama, Georgia, South Carolina, North Carolina, Tennessee, Arkansas, Kentucky, Florida),\n   3. Identify as heterosexual and cisgender, and\n   4. Report non-acceptance of their SGMY.\n2. SGMY are eligible if they meet the following criteria:\n\n   1. Self-identify as SGM,\n   2. Are 15-29 years old,\n   3. Live in the Southeast United States, and\n   4. Have a parent enrolled in the trial\n\n   Exclusion Criteria:\n3. Any individual who meets any of the following criteria will be excluded from participation in this study:\n\n   1. Active mania, psychosis, or suicidality, and\n   2. Unable to provide informed consent.","15 Years",{"count":480,"type":23},129,[482],"PHASE1","The purpose of this study is to develop and test two brief online writing interventions to improve parental acceptance of sexual and gender minority youth (SGMY) in the Southeast United States.",[30],[486,487],"Parental Acceptance","Sexual and Gender Minority Youth",{"date":489,"type":38},"2026-01-09",{"date":491,"type":38},"2023-11-29",{"date":493,"type":23},"2026-08-31",{"name":438,"class":45},4,{"id":497,"slug":498,"hasResults":12,"nctId":499,"briefTitle":500,"officialTitle":500,"acronym":501,"eligibilityCriteria":502,"healthyVolunteers":172,"sex":18,"minAge":503,"maxAge":504,"enrollmentInfo":505,"targetDuration":4,"studyType":24,"phases":506,"briefSummary":507,"conditions":508,"keywords":509,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":514,"lastUpdatePostDateStruct":515,"startDateStruct":517,"completionDateStruct":518,"leadSponsor":520,"locationsCount":46},"100604721","promoting-socioemotional-development-in-early-childhood-implementation-and-evaluation-of-the-vipp-sd-parenting-intervention-in-portugal-100604721","NCT07153198","Promoting Socioemotional Development in Early Childhood: Implementation and Evaluation of the VIPP-SD Parenting Intervention in Portugal","SAF-Parents","Inclusion Criteria: Children will be between 2 and 6 years old, and their parents between must be fluent in Portuguese -\n\nExclusion Criteria: Children with disabilities, chronic illnesses, or hereditary diseases will be excluded from the study\n\n\\-","2 Years","5 Years",{"count":56,"type":23},[26],"The Video-feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) is an attachment-based intervention aimed at promoting parental sensitivity and the use of developmentally appropriate, non-coercive discipline strategies (ref). The VIPP-SD intervention integrates the enhancement of parental sensitive responsiveness (Ainsworth et al., 1974) with parent coaching aimed at preventing coercive parent-child interaction cycles (Patterson, 1982) and facilitating sensitive limit-setting practices.ase parental sensitivity and sensitive discipline of the primary parent",[30],[510,511,512,513],"sensitivity","attachment","behavioral problems","economic advantages","2026-01-01",{"date":516,"type":38},"2026-01-05",{"date":514,"type":38},{"date":519,"type":23},"2027-12-31",{"name":521,"class":45},"ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida",{"id":523,"slug":524,"hasResults":12,"nctId":525,"briefTitle":526,"officialTitle":526,"acronym":4,"eligibilityCriteria":527,"healthyVolunteers":172,"sex":528,"minAge":529,"maxAge":197,"enrollmentInfo":530,"targetDuration":4,"studyType":24,"phases":531,"briefSummary":532,"conditions":533,"keywords":538,"overallStatus":291,"whyStopped":4,"lastUpdateSubmitDate":543,"lastUpdatePostDateStruct":544,"startDateStruct":546,"completionDateStruct":548,"leadSponsor":550,"locationsCount":46},"100615671","mobile-prenatal-education-for-expectant-fathers-and-its-effects-on-bonding-stress-breastfeeding-and-marital-satisfaction-100615671","NCT07295639","Mobile Prenatal Education for Expectant Fathers and Its Effects on Bonding, Stress, Breastfeeding and Marital Satisfaction","Inclusion Criteria:\n\n* Age between 19 and 65 years\n* First-time father\n* Has become a father within the last month\n* Has a healthy newborn without congenital anomalies or chronic illnesses\n* Does not have a premature or low-birth-weight baby\n* Has not become a father through adoption\n* Owns a mobile phone capable of accessing the mobile-based application\n* Has an Android or iOS operating system\n* Has not received any infant care training within the last 6 months\n* Has no physical or mental disability that would prevent viewing, hearing, or understanding the research questions or educational content\n* Voluntarily agrees to participate in the research\n\nExclusion Criteria:\n\n* Declines to participate in the research\n* Does not own a smartphone\n* Cannot use mobile applications\n* Has a physical or mental condition that prevents completing the questionnaires\n* Has a baby with congenital anomalies or chronic medical conditions\n* Has a premature or low-birth-weight baby\n* Has received infant care training within the last 6 months\n* Has adopted a child\n* Is outside the 19-65 age range","MALE","19 Years",{"count":113,"type":23},[26],"The aim of this interventional clinical trial is to assess whether a mobile-based antenatal education programme for expectant fathers has a positive effect on father-infant bonding, stress levels, and breastfeeding attitudes.\n\nThe study aims to answer the following main questions:\n\nDoes participation in a mobile-based prenatal education programme strengthen fathers' emotional bonds with their babies? Does the education reduce fathers' stress levels during the prenatal and postnatal periods? Does it increase the father's knowledge and supportive attitude towards breastfeeding? Researchers will compare whether there are measurable differences in attachment, stress, and breastfeeding attitudes between the intervention group (fathers receiving mobile-based education) and the control group (fathers receiving standard routine information).\n\nParticipants: Will complete pre- and post-intervention questionnaires assessing attachment, stress, and breastfeeding attitudes.\n\nThe intervention group will have access to a six-module mobile application covering topics such as infant care, nutrition, sleep routines, health and safety, emotional development, and daily care practices.\n\nThe study will be conducted with fathers aged 19-65 who became fathers within the last month and voluntarily agreed to participate.",[534,535,536,537,30],"Breastfeeding Attitudes","Breast Feeding","Paternal Behavior","Health Education",[539,540,541,542],"father-infant bonding","paternal stress","breastfeeding attitudes","mobile-based education","2025-12-16",{"date":545,"type":38},"2025-12-19",{"date":547,"type":23},"2026-01",{"date":549,"type":23},"2026-10",{"name":551,"class":45},"Gaziantep Islam Science and Technology University",{"id":553,"slug":554,"hasResults":12,"nctId":555,"briefTitle":556,"officialTitle":557,"acronym":558,"eligibilityCriteria":559,"healthyVolunteers":172,"sex":18,"minAge":560,"maxAge":561,"enrollmentInfo":562,"targetDuration":4,"studyType":336,"phases":4,"briefSummary":564,"conditions":565,"keywords":572,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":578,"lastUpdatePostDateStruct":579,"startDateStruct":580,"completionDateStruct":582,"leadSponsor":584,"locationsCount":133},"100578382","the-effect-of-mobile-devices-on-the-development-and-health-of-young-children-100578382","NCT06810570","The Effect of Mobile Devices on the Development and Health of Young Children","Understanding the Impact of Interactive Electronic Devices on Young Children's Development and Health: the iKids Study","iKids","Inclusion Criteria:\n\n* Children between 36 and 48 months old at the time of enrolment, who have received parent\u002Fcarer consent for participation and provided verbal assent\n\nExclusion Criteria:\n\n* Parents or child do not speak and\u002For understand English.\n* Child who is clinically diagnosed with a developmental disorder by a medical professional prior to either baseline or follow-up assessments.","36 Months","48 Months",{"count":563,"type":23},874,"Interactive electronic devices (IEDs) have become a common part of young children's lives, yet research on this topic remains limited. Most studies utilise cross-sectional designs and present inconsistent evidence regarding the benefits and harms of IED use. Some findings suggest that IEDs may negatively impact sleep quality, be linked to visual impairment, and lead to reduced and more negative interactions between parents and children. However, it might also have a positive effect in helping language learning in young children when IEDs are co-viewed with parents and improving literacy, mathematics and science skills.\n\nDue to this conflicting evidence, health guidelines for young children do not provide specific recommendations on using these devices, leading policymakers to request more information in this area. In conversation with parents and nursery practitioners, they told us they were confused about the benefits and hams of using these devices and wanted further guidance.\n\nThe primary aim of this study is to investigate the long-term association between IED use (duration and mode) and development outcomes in 3-to-5-year-old children. The researchers will also explore the longitudinal association between IED use (duration) and other outcomes, including BMI z-score, movement behaviour, motor skills, parent-child interaction and school readiness.\n\nChildren and their parents or caregivers from both low, mid and high-income areas in England will be invited to take part. Children can participate if they are between 3 and 4 years old when they join the study, have received consent from their parent or caregiver, and have provided verbal agreement to participate. However, children will not be eligible if their parents or caregivers do not speak or understand English or if the child has been diagnosed with a developmental disorder by a medical professional before the baseline or follow-up measurements.\n\nData collection will occur at the start of the study and one year later when children are 4 to 5 years old. Parents will be asked to download an app called EARS on the smartphone and\u002For tablet that the child uses. The app will measure how long they use the device (IED duration) and the specific apps accessed during device usage (IED mode).\n\nChild development will be assessed through the following measures: 1) working memory, including visual-spatial and phonological aspects; 2) ability to control, referred to as inhibition; 3) the ability to control and redirect attention, defined as shifting; 4) self-regulation; 5) social development; 6) numeracy skills; and 7) expressive vocabulary. Child development will be measured using the Early Years Toolbox app and recorded on an iPad.\n\nThe researchers will also measure a set of secondary outcomes, including 1) BMI z-score; 2) 24-hour movement behaviour (i.e. physical activity, sedentary behaviour and sleep); 3) motor development (i.e., gross motor skills and fine motor skills); 4) parent-child interaction; 5) school readiness.\n\nThe researchers will also measure other things that might influence IED use or emerging abilities, such as participants' demographics (i.e., sex, age, ethnicity and caregiver education), parenting styles, parents' smartphone addiction, the presence of screen viewing policy at the early year's settings.\n\nTo thank the early years settings for participating, each will receive £100 for every data collection session. Parents will receive a £30 high street e-voucher for each data collection session in which they participate. There are no risks of physical injury or harm involved in this study. All researchers entering the nursery will have been subject to an enhanced Disclosure and Barring Service (DBS) check and are permitted to engage in controlled activity. If the research team observes a significant developmental delay in the child while conducting the health and development measures, they will notify the nursery staff, who will then communicate this information to the parents. Parents may feel uncomfortable downloading the app (EARS) onto their electronic devices to track how long the device is being used and the type of apps in use. The app has been designed for research purposes and approved by Sheffield Hallam University Digital Technology Services. Participants will download the app through the official Apple or Google Stores, which offers additional security and convenience. Participants will be advised to delete the app after each data collection point.\n\nThe investigators will have regular group meetings throughout the project with parents, carers, nursery teachers and policymakers to gather ideas and opinions and share our findings. These discussions will help researchers improve the project.\n\nThe findings will help inform public health guidance on children's device usage. The researchers will share the knowledge gained from this study with all participants, write policy briefs and scientific papers, and present the findings at conferences.",[566,567,568,569,30,570,571],"Development and Health","Behavior and Behavior Mechanisms","Cognition","Physical Health","Education","Technology Use",[573,574,575,576,577],"early years","mobile devices","cognitive development","socio emotional development","physical development","2025-12-12",{"date":545,"type":38},{"date":581,"type":38},"2025-01-13",{"date":583,"type":23},"2027-01-31",{"name":585,"class":45},"Sheffield Hallam University",{"id":587,"slug":588,"hasResults":12,"nctId":589,"briefTitle":590,"officialTitle":591,"acronym":592,"eligibilityCriteria":593,"healthyVolunteers":172,"sex":18,"minAge":274,"maxAge":390,"enrollmentInfo":594,"targetDuration":4,"studyType":24,"phases":595,"briefSummary":596,"conditions":597,"keywords":608,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":611,"lastUpdatePostDateStruct":612,"startDateStruct":614,"completionDateStruct":616,"leadSponsor":618,"locationsCount":46},"100567397","a-mobile-app-to-improve-24-hour-movement-guideline-adherence-in-preschoolers-100567397","NCT06667661","A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers","A Home-Based Intervention to Improve Adherence to the 24-Hour Movement Guidelines in Young Children","Shining Star","Inclusion (Child):\n\n* Ages 3-4 years.\n* Parent report that they meet 0 or 1 recommendation for physical activity, sleep, and screen-time as defined by the 24-hour movement guidelines. The physical activity recommendation is defined as greater than or equal to 3 hours\u002Fday of total physical activity, including 1 hour of moderate-to-vigorous physical activity. The sleep recommendation is defined as 10-13 hours\u002Fday. The sedentary behavior recommendation is defined as less than or equal to 1 hour\u002Fday of sedentary screen-time.\n\nInclusion (Parents):\n\n* Parents must agree to use their mobile phone for the duration of the study (\\~12 weeks) and download the mobile app onto their phone.\n* The parent\u002Fcaregiver is fluent in English to participate in testing the mobile app.\n* The parent\u002Fcaregiver must be willing to travel to KUMC to complete study visits.\n\nExclusion (child):\n\n* Mobility limitations as reported by the parent.\n* Meeting two or more recommendations for physical activity, sleep, and screen-time.\n* Sibling or household member is participating or participated in the study.",{"count":113,"type":23},[26],"The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the guidelines for physical activity, sedentary behavior, and sleep. The main questions it aims to answer are:\n\n* Can the intervention increase the proportion of children meeting all three 24-Hour Movement Guidelines (physical activity, screen-time, and sleep)?\n* Is the intervention feasible for parents to implement, as measured by a parent feedback survey?\n\nResearchers will compare an intervention group to a waitlist control group to assess whether the intervention leads to increased guideline adherence.\n\nParents and Participants:\n\n* Children will wear an accelerometer to track physical activity and sleep patterns.\n* Parents will use a mobile app that delivers weekly lessons and behavior-related goals to encourage healthy movement behaviors in their children.\n* Parents will complete questionnaires on their child's movement behaviors and development at baseline, 6 weeks, and 12 weeks.\n* Additionally, children will undergo motor skills assessments, and parents will provide feedback on cognitive development and behavioral changes.",[598,599,600,601,602,603,604,605,568,30,606,537,607],"Healthy","24-Hour Movement Guidelines","Feasibility Studies","Sleep","Physical Activity","Screen Time","Sedentary Behaviors","Motor Skills","Mobile Application","Child Development",[602,609,601,607,605,610,598,599,603,604,568,30,606,537],"Sedentary Behavior","Behavioral problems","2025-12-03",{"date":613,"type":38},"2025-12-11",{"date":615,"type":38},"2025-01-29",{"date":617,"type":23},"2026-12-31",{"name":619,"class":45},"University of Kansas Medical Center",{"id":621,"slug":622,"hasResults":12,"nctId":623,"briefTitle":624,"officialTitle":625,"acronym":4,"eligibilityCriteria":626,"healthyVolunteers":172,"sex":18,"minAge":4,"maxAge":627,"enrollmentInfo":628,"targetDuration":4,"studyType":24,"phases":630,"briefSummary":631,"conditions":632,"keywords":633,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":639,"lastUpdatePostDateStruct":640,"startDateStruct":642,"completionDateStruct":644,"leadSponsor":646,"locationsCount":46},"100334953","centeringparenting-clinical-intervention-on-kindergarten-readiness-in-early-childhood-100334953","NCT03641092","CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood","Evaluation of the Impact of the CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood","Inclusion Criteria:\n\nFor participating practice sites\n\n* Practice provides care to patients who are covered by public insurance and\u002For uninsured (no minimum threshold: all insurance types eligible)\n* Practices have at least 3,000 primary care visits per year\n\nFor parent-child dyad\n\n* Index child age must be 0-3 months\n* Parent must be female\n* Parent must be 18 years of age and older\n* Parent and child must attend one of the 10 study clinical sites\n* Parental consent\n* Parent must be fluent in English or Spanish\n\nExclusion Criteria:\n\nFor participating practice sites\n\n* Does not accept public insurance\n\nFor parent-child dyad\n\n* Child born prior to 34 weeks gestation\n* Child with chronic conditions known to affect neurodevelopment\n* Child with a positive screen on the Children with Special Healthcare Needs screener","3 Months",{"count":629,"type":23},1200,[26],"Disparities in health begin in early childhood. Early life experiences influence brain development and have significant implications on future health and developmental outcomes. Low-income children are at greater risk of developmental delays in large part due to a lack of an enriched environment. Disparities in early childhood development increase risk for stunted academic achievement throughout the life course. Primary care is a universal exposure in early childhood and therefore is also a significant entry point for promoting optimal child development.\n\nThere is a need to provide effective, low-cost, and scalable interventions in primary care to support early childhood development.The CenteringParenting intervention is designed to reduce negative health and developmental outcomes within a model of group routine child health care. To date, there is no evidence of the benefits of the CenteringParenting intervention on school readiness, or improvements in parental behaviors that support optimal developmental milestones and achievement. The intent of this study is to determine the effectiveness of the CenteringParenting intervention on school readiness in early childhood, as measured by language development at 24 months, (in addition to health care utilization, child routine care maintenance, parenting stress, caregiver behaviors and attitudes).",[30,65,607,252],[634,635,636,637,638],"School readiness","Child development","Child behavior","Parenting behavior","CenteringParenting","2025-11-26",{"date":641,"type":38},"2025-12-01",{"date":643,"type":38},"2019-02-19",{"date":645,"type":23},"2026-09",{"name":647,"class":45},"Boston Medical Center",{"id":649,"slug":650,"hasResults":12,"nctId":651,"briefTitle":652,"officialTitle":653,"acronym":654,"eligibilityCriteria":655,"healthyVolunteers":172,"sex":18,"minAge":274,"maxAge":504,"enrollmentInfo":656,"targetDuration":4,"studyType":24,"phases":657,"briefSummary":658,"conditions":659,"keywords":661,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":666,"lastUpdatePostDateStruct":667,"startDateStruct":669,"completionDateStruct":671,"leadSponsor":672,"locationsCount":46},"100410661","project-peak-early-intervention-for-adhd-100410661","NCT04627415","Project PEAK: Early Intervention for ADHD","Early Intervention for Young Children At-Risk for ADHD: Evaluating Efficacy and Delivery Format for Behavioral Parent Education","PEAK","Inclusion Criteria:\n\n* 3- to 5.11-year old children with clinically significant symptoms of ADHD.\n* Children had to have met DSM-5 criteria for one of the three presentations of ADHD based on clinical interview and parent and teacher behavior ratings, including parent and teacher report of elevated levels of impairment at home and school (i.e., score greater than 90th percentile on one or more Conners Early Childhood Rating Scale subscales relevant to ADHD).\n\nExclusion Criteria:\n\n* A diagnoses of autism spectrum disorder (ASD), pervasive developmental disorder, intellectual disability, neurological damage, or significant motor or physical impairments.\n* Children needed to be enrolled in a pre-school or day care setting at least 2 days a week unless otherwise unable to enroll (e.g. behavioral problems, lack of services for unrelated disability) in order to establish the presence of symptoms across two settings.",{"count":392,"type":23},[26],"Parent education is an effective and relatively cost efficient approach for reducing child behavior problems. Research, however, suggests that the effectiveness of parent education is mitigated by parent attendance and parent implementation of intervention strategies. That is, low attendance at parent education sessions is associated with limited intervention effects. Therefore, it is critical to identify strategies to enhance parent engagement. A previous pilot randomized controlled trial of a parent education program (Behavioral Parent Education; BPE, specifically Promoting Engagement for ADHD pre-Kindergartners \\[PEAK\\]), found that both face-to-face (F2F) and online BPE resulted in high levels of parent engagement and child behavior improvements. However, results need to be replicated in a full scale efficacy trial with a larger, diverse sample to provide more reliable estimates of relative effect sizes for parent and child outcomes and to evaluate the extent to which parent and child behavior changes are maintained after BPE has ended. In the current randomized controlled trial, the investigators intend to apply What Works Clearinghouse group design standards to examine the efficacy of two forms of delivery of BPE (F2F and online) relative to a wait-list control condition in a sample of 180, 3- to 5-year old children with clinically significant symptoms of ADHD. The objective is to: (a) extend findings from the pilot investigation to a large, diverse sample; (b) examine maintenance of effects; (c) identify moderators and mediators of treatment outcome, especially the degree to which these may differ for F2F vs. online treatment delivery; and (d) assess cost and cost-effectiveness of the two PEAK delivery formats.",[660,30,252,65],"Attention Deficit Hyperactivity Disorder",[662,663,664,665],"ADHD","Behavioral Parent Training","Early Intervention","Preschool","2025-09-02",{"date":668,"type":38},"2025-09-09",{"date":670,"type":38},"2020-09-01",{"date":617,"type":23},{"name":673,"class":45},"Lehigh University",{"id":675,"slug":676,"hasResults":12,"nctId":677,"briefTitle":678,"officialTitle":679,"acronym":680,"eligibilityCriteria":681,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":682,"targetDuration":4,"studyType":24,"phases":684,"briefSummary":685,"conditions":686,"keywords":688,"overallStatus":291,"whyStopped":4,"lastUpdateSubmitDate":693,"lastUpdatePostDateStruct":694,"startDateStruct":696,"completionDateStruct":698,"leadSponsor":700,"locationsCount":46},"100583336","effects-of-parenting-in-sweden-on-trust-in-social-services-100583336","NCT06874998","Effects of \"Parenting in Sweden\" on Trust in Social Services","Effects of \"Parenting in Sweden\" on Trust in Social Services - a Randomized Controlled Trial","PiSRCT","Inclusion Criteria:\n\n* All parents invited to participate in PiS can take part in the study.\n* Eligibility extends to parents born outside of Sweden who have children aged 0 to 17 years.\n* There are no restrictions regarding the length of time since their migration to Sweden; i.e., participants may have lived in Sweden for decades prior to joining. - - Literacy is not a requirement for participation.\n\nExclusion Criteria:\n\n* Individuals who are unable, physically or not willing, to sign a consent form will not be eligible to participate in the study.",{"count":683,"type":23},200,[26],"Supporting Parents in a New Country\n\nAdjusting to parenthood in a new country presents significant challenges. Many immigrant parents face language barriers, financial difficulties, and cultural differences that can complicate their ability to support their children's adaptation to Swedish society. These challenges can contribute to increased stress within the family and, in some cases, elevate the risk of child maltreatment-particularly in socioeconomically disadvantaged areas. However, research suggests that strong social support and positive parenting strategies can mitigate these risks.\n\nSweden, known for its high levels of trust in authorities, has implemented various initiatives to assist families, especially those new to the country. One such initiative is Parenting in Sweden (PiS), a structured program designed to help foreign-born parents navigate Swedish society, understand their rights, and support their children's development. Delivered in five sessions, the program covers key topics such as the Swedish school system, healthcare services, parental rights, and challenges related to raising teenagers.\n\nThis study aims to assess whether participation in PiS increase parents' trust in social services. Additionally, it explores whether the program encourages parents to enroll their children in extracurricular activities, which are known to support child development. Another important aspect under investigation is whether the program can help reduce the risk of parents resorting to harsh disciplinary practices.\n\nTo evaluate these outcomes, the study follows a randomized controlled trial (RCT) design. Immigrant parents of children aged 0-17 are invited to participate, with half assigned to complete the full five-session program and the other half (control group) placed on a waiting list, receiving a group meeting to discuss films related to moving to Sweden. All participants will complete surveys assessing their trust in social services, their children's participation in extracurricular activities, and their parenting practices. These surveys will be administered before and after the program, as well as six months later, to track any changes over time.\n\nThe primary objective is to determine whether participation in PiS leads to increased trust in social services. Additional expected benefits (exploratory analysis) include promoting positive parenting behaviors, such as seeking help when needed and actively engaging children in structured activities outside of school.\n\nBy examining the effectiveness of parental support programs facilitating integration, this study aims to contribute to a deeper understanding of how structured interventions can help families navigate life in Sweden. If the program proves successful in fostering trust and encouraging positive parenting, it may have long-term benefits for both parents and children, ultimately supporting their well-being and integration into Swedish society.",[30,687],"Immigrant",[689,65,690,691,692],"Parental support programs","Immigrant parents","Trust in social services","Cultural adaptation","2025-07-09",{"date":695,"type":38},"2025-07-14",{"date":697,"type":23},"2025-09",{"date":699,"type":23},"2026-04",{"name":701,"class":45},"Karolinska Institutet",{"id":703,"slug":704,"hasResults":12,"nctId":705,"briefTitle":706,"officialTitle":707,"acronym":708,"eligibilityCriteria":709,"healthyVolunteers":172,"sex":18,"minAge":390,"maxAge":365,"enrollmentInfo":710,"targetDuration":4,"studyType":24,"phases":711,"briefSummary":712,"conditions":713,"keywords":717,"overallStatus":291,"whyStopped":4,"lastUpdateSubmitDate":726,"lastUpdatePostDateStruct":727,"startDateStruct":729,"completionDateStruct":731,"leadSponsor":733,"locationsCount":4},"100596912","dino-study-daily-intervention-based-research-on-nurturing-opportunities-in-young-children-100596912","NCT07051642","Dino Study: Daily Intervention-based Research on Nurturing Opportunities in Young Children","The Dino Study: Rationale and Study Protocol for a Randomized Controlled Trial Evaluating the Incredible Years Dinosaur Program With Daily Assessments","Dino","Inclusion Criteria:\n\n* Children aged 4 to 8 years\n* At least one parent or primary caregiver willing and able to participate in the study and complete daily diary assessments\n* Sufficient Dutch language proficiency in child and parent to complete questionnaires and daily diary reports\n* Parental indication that the child shows elevated or (sub)clinical levels of conduct problems in daily life (e.g., frequent defiance, aggression, or rule- breaking behavior\n\nExclusion Criteria:\n\n* Intellectual disability in the child (IQ \\\u003C 70)\n* Child lives primarily in a different household during weekdays (e.g., institutional care, full-time co-parenting arrangement)\n* Parent\u002Fchild does not have sufficient Dutch language proficiency",{"count":56,"type":23},[26],"The goal of this clinical trial is to evaluate the effectiveness of the Incredible Years Dinosaur Program in children aged 4 to 8 years with conduct problems. The main questions it aims to answer are:\n\n* Does participation in the Dinosaur Child Program lead to greater improvements in children's emotional, social, and cognitive functioning, and reductions in externalizing behavior compared to a waitlist control group?\n* Does the intervention reduce emotional variability and daily behavior problems as captured through daily diary assessments?\n* Does the intervention improve daily parent-child dynamics, including reduced emotional escalation and more shared positive affect?\n\nResearchers will compare children in the intervention group to those in the waitlist control group to see if the program leads to better emotional regulation, fewer behavior problems, and improved parent-child interactions.\n\nParticipants will:\n\n* Be randomly assigned to either the intervention or waitlist control group (1:1) Receive 18 weekly small-group sessions (if in the intervention condition) using the Incredible Years Dinosaur Program\n* Complete daily diaries with their parent using the m-Path app during a 20-week period (baseline, intervention, follow-up)\n* Complete standardized pre- and post-intervention assessments via parent, teacher, and child reports",[714,30,715,716],"Behavior Problems in Children","Oppositional Behavior","Social Skills",[718,719,720,721,722,723,724,725],"Incredible Years Dinosaur Program","Conduct problems","Emotional sensitivity","Parent-child interaction","Daily diary","Experience Sampling Method","Randomized controlled trial","Behavioral intervention","2025-07-07",{"date":728,"type":38},"2025-07-10",{"date":730,"type":23},"2025-09-15",{"date":732,"type":23},"2026-04-30",{"name":734,"class":45},"Tilburg University"]