[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parent-child-relationship\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parent-child-relationship":202},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,52,91,113,144,174],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100611437","randomized-controlled-trial-of-a-family-focused-intervention-for-caregivers-and-young-adolescents-phase-3-of-flourish-100611437",false,"NCT07240571","Randomized Controlled Trial of a Family-focused Intervention for Caregivers and Young Adolescents (Phase 3 of FLOURISH)","Family-Focused Adolescent & Lifelong Health Promotion: Prevention of Adolescent Mental Health Problems in Eastern Europe","FLOURISH","Inclusion Criteria:\n\n* For Caregivers:\n\nMust be 18 years or older at baseline assessment\n\nMust be the primary caregiver of an adolescent aged 10-14 who has resided in the same household for at least four nights a week in the past month\n\nMust be able to speak at least one of the local languages in which the program will be offered (e.g., Macedonian, Romanian, Russian, Ukrainian or Albanian)\n\nMust agree to participate in the program and provide informed consent for both themselves and their adolescent\n\nFor Adolescents:\n\nMust be aged 10-14 at the baseline assessment\n\nMust provide assent to participate in the study\n\nMust have caregiver consent to participate.\n\nExclusion Criteria:\n\n* No formal exclusion criteria have been established for the FLOURISH project. However, during the study introduction, the research team will guide participants through a consent form that asks whether they are currently experiencing acute distress or a mental or physical health condition that could interfere with participation. The decision to participate will be made by the individual. If a potential participant indicates they are unable to take part due to acute health issues, the research team will provide appropriate referrals to other services.",true,"ALL","10 Years","14 Years",{"count":22,"type":23},1280,"ESTIMATED","INTERVENTIONAL",[26],"NA","The aim of this study is to conduct a multi-country randomized waitlist controlled trial to evaluate the effectiveness, cost-effectiveness, and scalability of the optimized Parenting for Lifelong Health (PLH) for Parents and Teens program in Moldova and North Macedonia. In Phase 2 of the FLOURISH project, a factorial trial tested multiple intervention components and identified the optimized intervention package. In Phase 3, this trial will assess the implementation, outcomes, and economic impact of the optimized PLH program delivered to adolescents aged 10-14 and their caregivers. ALTERNATIVA will deliver the program in North Macedonia and the Health for Youth Association in the Republic of Moldova.",[29,30,31,32],"Adolescent - Emotional Problem","Parent Child Relationship","Family Functioning","Well-Being, Psychological",[34,35,36,37,38],"Multiphase Optimization Strategy (MOST)","Family-based intervention","Adolescents","Mental health","Randomized trial","RECRUITING","2026-05-28",{"date":42,"type":43},"2026-06-02","ACTUAL",{"date":45,"type":43},"2025-10-24",{"date":47,"type":23},"2026-11-30",{"name":49,"class":50},"University of Klagenfurt","OTHER",2,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":24,"phases":63,"briefSummary":64,"conditions":65,"keywords":73,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":90},"100633658","the-new-beginnings-podcast-brief-audio-intervention-for-parents-from-divorced-and-separated-families-100633658","NCT07529548","The New Beginnings Podcast: Brief Audio Intervention for Parents From Divorced and Separated Families","\"The New Beginnings Podcast: A Small-scale Randomized Controlled Trial of a Parenting Podcast to Improve Outcomes for Children From Divorced Families\"","NBP-P","Inclusion Criteria:\n\nFor Parents, eligibility criteria are:\n\n1. divorced, separated, separated but never married, or divorcing\u002Fseparating within the last two years;\n2. one or more children between the ages of 8-18 years old;\n3. have in-person contact with their child(ren) at least three hours per week or have at least one overnight visit every other week;\n4. have access to a smartphone with internet that can play audio files;\n5. English speaking.\n\nFor children, eligibility criteria are:\n\n1. have a parent who is participating in the trial;\n2. be between the ages of 8-18 and\n3. have access to a computer to complete assessments. If a parent has more than one child aged 8-18 interested in participating, we will randomly select one child to ensure independence of responses.\n\nExclusion Criteria:\n\n\\-","8 Years",{"count":62,"type":23},80,[26],"The goal of this study is to learn if the New Beginnings Podcast can help children whose parents are going through a divorce or separation. The podcast shares parenting strategies that have been shown to help in past in-person and online programs. This study will also look at how easy it is for parents to use the podcast and how helpful they find it.\n\nThe main questions it aims to answer are:\n\n1. Do parents find the podcast easy to use, helpful, and relevant?\n2. Does listening to the podcast improve children's mental health?\n3. Does the podcast help parents build stronger relationships with their children and reduce conflict between parents?\n\nResearchers will compare families who use the podcast to families on a waitlist to see if the podcast makes a difference.\n\nParticipants will:\n\n1. Listen to podcast episodes over the course of the study\n2. Answer questions about their experiences with the podcast\n3. Complete surveys about their child's well-being, their parenting, and family relationships\n\nThis study will include 80 parents and their children.",[30,66,67,68,69,70,71,72],"Parenting Intervention","Parenting Behaviour","Interparental Conflict","Feasibility Study","Acceptability","Appropriateness","Child Mental Health",[74,75,76,77,78,79,66,80,72],"Parenting","Divorce","Separation","Separated and Divorced Parents","Podcast","Prevention","New Beginnings Program","2026-04-10",{"date":83,"type":43},"2026-04-14",{"date":85,"type":43},"2025-08-15",{"date":87,"type":23},"2026-12",{"name":89,"class":50},"Charla Aubrey Rhodes",1,{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":95,"acronym":4,"eligibilityCriteria":96,"healthyVolunteers":17,"sex":18,"minAge":97,"maxAge":4,"enrollmentInfo":98,"targetDuration":4,"studyType":24,"phases":100,"briefSummary":101,"conditions":102,"keywords":4,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":4},"100633426","family-relationship-help-100633426","NCT07526532","Family Relationship Help","Inclusion Criteria:\n\nAdult in parent-child pair:\n\n1. Are 18+\n2. Live in the US\n3. Are a parent-child pair (both parent and child must be in the study to be eligible)\n4. Are comfortable with digital tools and can access ChatGPT\n\nChild in parent-child pair:\n\n1. Are 12-17\n2. Live in the US\n3. Are a parent-child pair (both parent and child must be in the study to be eligible)\n4. Are comfortable with digital tools and can access ChatGPT\n\nExclusion Criteria:\n\n* Non-English speaker","12 Years",{"count":99,"type":23},120,[26],"We are testing whether different communication methods including use of technology can affect relationship satisfaction and well-being in a parent-child relationship. We believe that those who regularly use a chatbot with communication will improve relationship satisfaction in their familial relationship.",[30],"NOT_YET_RECRUITING","2026-04-06",{"date":106,"type":43},"2026-04-13",{"date":108,"type":23},"2026-04",{"date":110,"type":23},"2026-09",{"name":112,"class":50},"University of California, Irvine",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":17,"sex":18,"minAge":121,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":24,"phases":124,"briefSummary":125,"conditions":126,"keywords":129,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":90},"100625106","grow-together-thrive-together-a-feasibility-study-of-a-brief-relationship-intervention-for-emerging-adults-and-their-caregivers-100625106","NCT07418320","Grow Together, Thrive Together: A Feasibility Study of a Brief Relationship Intervention for Emerging Adults and Their Caregivers","Grow Together, Thrive Together (G2T2): A Feasibility Study of a Brief Writing-Based Relationship Intervention for Emerging Adults and Their Caregivers","G2T2","Inclusion Criteria:\n\n* Emerging adults aged 18-25 years and their primary caregiver or parent, enrolled as emerging adult-caregiver dyads\n* Both members of the dyad must independently provide informed consent prior to participation\n* Sufficient English literacy to complete online questionnaires in English\n* Reliable access to the internet via a computer or mobile device\n* Dyad members may live together or separately\n* Participants may continue usual or recommended mental health care (e.g., psychotherapy, pharmacotherapy) during the study\n\nExclusion Criteria:\n\n* Concurrent participation in a structured family-based intervention (e.g., manualized family therapy or family skills programs) during the study period","18 Years",{"count":123,"type":23},60,[26],"Background. Emerging adulthood is a period of major change in young people's lives, including increased independence, new responsibilities, and shifting relationships with parents or caregivers. During this time, disagreements between emerging adults and caregivers are common and may become more frequent or emotionally intense. How families manage these disagreements may affect relationship quality and emotional well-being for both emerging adults and caregivers. However, there are few brief, accessible programs designed to support emerging adults and caregivers together during this transition.\n\nGrow Together, Thrive Together (G2T2) is a brief, online, writing-based relationship program designed for emerging adults and their caregivers. The program encourages participants to reflect on disagreements using a neutral, outside-observer perspective, with the goal of helping families approach conflict in healthier ways. G2T2 is designed to be low-intensity, self-directed, and accessible, and can be completed remotely using secure online platforms.\n\nThe purpose of this study is to evaluate the feasibility and acceptability of the G2T2 program and study procedures, rather than to test effectiveness. This feasibility clinical trial will examine whether emerging adult-caregiver dyads can be successfully recruited and retained, whether participants complete the writing sessions as planned, and whether participants find the program acceptable, easy to use, and understandable. The study will also explore whether participants report using the conflict reappraisal strategy outside of the writing sessions and examine changes in relationship and conflict-related outcomes before and after the program to inform future research.\n\nParticipants will take part as emerging adult-caregiver pairs. Each participant will complete an online baseline survey, three brief online writing sessions completed over approximately nine weeks, and a follow-up survey one week after the final session. Each writing session includes brief questions about recent disagreements, a short instructional video, brief questions to check understanding of the strategy, and guided writing exercises focused on reflecting on disagreements and planning how to use the strategy in future interactions. All activities are completed independently and online. Findings from this study will be used to refine the G2T2 program and study procedures and to inform the design of a future, larger randomized controlled trial.",[30,127,128],"Interpersonal Relations","Young Adults",[130,127,131,132,133,134],"Parent-Child Relations","Family Relations","Primary Prevention","Health Promotion","Emerging Adulthood","2026-02-10",{"date":137,"type":43},"2026-02-18",{"date":139,"type":23},"2026-03-20",{"date":141,"type":23},"2027-05-31",{"name":143,"class":50},"York University",{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":4,"eligibilityCriteria":150,"healthyVolunteers":17,"sex":151,"minAge":121,"maxAge":4,"enrollmentInfo":152,"targetDuration":4,"studyType":24,"phases":154,"briefSummary":155,"conditions":156,"keywords":160,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":90},"100572976","the-impact-of-an-evidence-based-parenting-service-on-maternal-sensitivity-and-infant-cellular-aging-in-a-population-of-under-resourced-families-100572976","NCT06740266","The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families","The Impact of Stress and Caregiver Sensitivity on Infant Cellular Aging in a Population of Under-Resourced Families: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Biological mother of infant aged 3-12 months English- or Spanish-speaking Receiving Medicaid Their infant is receiving pediatric care at WakeMed\n\nExclusion Criteria:\n\n* Experiencing an acute crisis (e.g. hospitalization, incarceration) Homeless or without stable enough housing for home visits Lacking access to a phone Previously received the Promoting First Relationships intervention","FEMALE",{"count":153,"type":23},250,[26],"The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets \"under the skin\" and influences long-term health. The investigators will test if the support given to parents of young children reduces childhood stress. The investigators will also test if the effects of mother's stress and Early Life Adversity can be passed down to children. Can it impact the child's long-term health? Researchers will compare the Promoting First Relationships® in Primary Care (PFR in PC) parenting program with Usual Care to see if PFR reduces mothers' stress, improves mother's sensitivity, and reduces accelerated cellular aging.\n\nParticipants will:\n\n* Be randomized to receive PFR in PC or Usual Care. PFR in PC is an evidence-based 10-week home visiting service, with 2 extra sessions at the WakeMed pediatric clinic. Usual Care is the health care and general services offered to families at the WakeMed pediatric clinic.\n* Have in-home research visits at the start of the study (Time 1, T1), about 6 months later (Time 2, T2), and 12 months later (Time 3, T3). Information collected at these visits includes:\n\n  * Answering questions about your background, past and current stress, physical and mental health, parenting behaviors, and child behavior problems (T1, T2, T3).\n  * Being videotaped doing a short teaching activity.\n  * Having a small amount of blood collected from the mother by finger prick (T1, T3).\n  * Having a small amount of blood collected from the infant by heel stick (T1, T3).",[30,157,158,159],"Child Social-Emotional Development","Telomere Length","Epigenetic Aging",[161,162,163,164],"Epigenetic aging","Parenting intervention","Parent sensitivity","Pediatric setting","2026-02-04",{"date":167,"type":43},"2026-02-06",{"date":169,"type":43},"2024-12-13",{"date":171,"type":23},"2029-04",{"name":173,"class":50},"University of Washington",{"id":175,"slug":176,"hasResults":11,"nctId":177,"briefTitle":178,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":11,"sex":18,"minAge":97,"maxAge":121,"enrollmentInfo":180,"targetDuration":4,"studyType":182,"phases":4,"briefSummary":183,"conditions":184,"keywords":187,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":201},"100590354","hold-me-tightlet-me-go-effectiveness-of-a-course-to-enhance-parent-adolescent-relationship-100590354","NCT06966323","Hold me Tight\u002FLet me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship","We will include:\n\n1. Families with one or both parents\u002Fprimary caretaker (single parent or blended families are allowed) with one adolescent of 12 to 18 years of age;\n2. Adolescent problems are deemed to be exacerbated by a stressful parent-adolescent relationship.\n\nWe will exclude:\n\n1. Participants in command of the Dutch language.\n2. Parents\u002Fprimary caretakers and adolescents with severe psychopathology (e.g., psychosis, acute suicidality, severe depression) that will interfere with participation in the program.\n3. Parents\u002Fprimary caretakers already attending systemic therapy or intensive parental guidance during the waiting period and during HmT\u002FLmG. Other individual therapy will be registered during intake, and afterwards by the therapists. During follow-up systemic interventions are allowed but have to be registered.",{"count":181,"type":23},150,"OBSERVATIONAL","HmT\u002FLmG is a group course for 4-6 parental dyads and consists of 4 group sessions with psycho-education and skills training and 3 individual sessions per family (i.e., 1 session with the adolescent, 1 session with the parents, and 1 session with parents and adolescent together). We want to evaluate effectiveness and treatment process mechanisms applying self-reports, audio observation and interviews.",[185,30,186],"Parent Training","Parent-child Problem",[188,189,190,191,36],"Hold Me Tight Program","Emotionally Focused Therapy","Parent Child Problems","Parent Child Relationships","2025-12-17",{"date":194,"type":43},"2025-12-24",{"date":196,"type":43},"2025-06-11",{"date":198,"type":23},"2028-09-01",{"name":200,"class":50},"University of Amsterdam",5,"Parent-Child Relationship"]