[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parenteral-support\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parenteral-support":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100488502","endoscopic-ultrasound-guided-large-diameter-lumen-apposing-metal-stent-gastro-gastrostomy-for-bypass-reversal-in-patients-with-roux-en-y-gastric-bypass-100488502",false,"NCT05640947","Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass","Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass: a Proof of Concent Study","LABOR","Inclusion Criteria:\n\n* Group 1) patients needing any kind of parenteral nutritional support (eg. hypo- albuminemia, hypovitaminoses, mineral deficiencies,...) that can not be corrected by dietary intervention\u002Foral supplementation\n* Group 2) patients with persistent invalidating symptomatic dumping syndrome despite optimal dietary intervention (typical complaints are headache, sweating, trembling, weakness and feeling hungry).\n* Group 3) patients with a refractory marginal ulcers with stenosis of the gastrojejunostomy leading to feading difficulties.\n* Group 4) patients with F3 or F4 liver fibrosis and a tendency to decompensation after bypass surgery, as demonstrated by an increase in serum bilirubin\u002FINR and\u002For lowering of serum albumin.\n\nExclusion Criteria:\n\n1. Uncorrectable coagulopathy\n2. Presence of significant portal hypertension as demonstrated by 2.1) the presence of esophageal and\u002For gastric varices AND\u002FOR 2.2) a hepatic venous pressure gradient (if measured) equal to or more than 10mm Hg AND\u002FOR 2.3) the combination of\n\n   1. a platelet count \\\u003C150000\u002Fµl AND\n   2. liver stiffness measured by elastometry equal to or more than 20 kPa (Baveno guidelines).\n3. Pregnant women, breastfeeding women or women that can not assure adequate anticonception for the duration of the study (based on anamnesis).\n4. Karnofsky index less than 60\n5. Vulnerable patients","ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary objective of this open-label pilot study is to investigate whether an endoscopically placed lumen apposing metal stent is an effective alternative to surgery in patients that have a clear indication for reversal of their gastric bypass.",[27,28,29,30,31],"Hypoglycemia","Gastric Outlet Obstruction","Steatohepatitis","Parenteral Support","Gastric Bypass","RECRUITING","2025-10-03",{"date":35,"type":36},"2025-10-08","ACTUAL",{"date":38,"type":36},"2023-01-30",{"date":40,"type":21},"2028-02",{"name":42,"class":43},"University Hospital, Ghent","OTHER",2]