[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parenting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parenting":28},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,43,0,25,[9,45,76,103,125,150,175,205,232,255,285,311,338,363,392,415,439,461,492,515,536,564,590,614,640],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100625076","hybrid-delivery-to-increase-access-and-sustainability-evaluating-ezparent-implementation-100625076",false,"NCT07417930","Hybrid Delivery to Increase Access and Sustainability: Evaluating ezParent Implementation","ezParent FT","Inclusion Criteria:\n\n* Parent or legal guardian of a 2-5-year-old child receiving services at the partnering organization site.\n* Speaks English or Spanish.\n* Has a smartphone, tablet, or computer with Wi-Fi access to receive the ezParent program.\n\nExclusion Criteria:\n\n• Parents who have previously participated in CPP or ezParent will be excluded.",true,"ALL","18 Years",{"count":21,"type":22},516,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this study is to evaluate the effects of the hybrid ezParent program (e.g., web-based training program plus synchronous group sessions) on parent and child outcomes in a community setting serving parents of children 2-5 years old. Parent participants will complete surveys at baseline, and 10 and 24-weeks post baseline.",[28,29,30,31],"Parenting","Prevention","Program Implementation","Early Childhood","NOT_YET_RECRUITING","2026-06-29",{"date":35,"type":36},"2026-07-01","ACTUAL",{"date":38,"type":22},"2026-08-01",{"date":40,"type":22},"2028-09-30",{"name":42,"class":43},"Klein Buendel, Inc.","INDUSTRY",1,{"id":46,"slug":47,"hasResults":12,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":17,"sex":51,"minAge":19,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":44},"100644016","phase-2-evaluating-the-effectiveness-of-the-common-elements-treatment-approach-ceta-in-peru-mechanisms-of-individual-and-intergenerational-change-100644016","NCT07667738","Evaluating the Effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of Individual and Intergenerational Change","Inclusion Criteria:\n\n* live in San Juan de Lurigancho, Lima, Peru,\n* be at least 18 years of age,\n* have a child between the ages of 4 and 6, and\n* have the ability to travel to INFAM for study assessments and treatment sessions\n\nExclusion Criteria:\n\n* living outside of San Juan de Lurigancho,\n* those who are unable or unwilling to attend in-person sessions, or\n* the presence of severe intellectual disabilities or mental illness (these individuals will be referred to other local services)","FEMALE",{"count":53,"type":22},600,[55],"PHASE2","Recent advances in intervention research have revealed the promise of transdiagnostic, modular approaches implemented by lay paraprofessionals for the treatment of the most prevalent mental health concerns in settings affected by adversity (e.g., anxiety, depression, posttraumatic stress), but to date, few effectiveness trials have examined the indirect effects of treatment on intergenerational and economic outcomes or moderators of treatment effectiveness. There is thus a critical need not only for the continued expansion of the evidence-basis for care in low-resource settings, but also for the evaluation of factors contributing to effectiveness across multiple dimensions to gain a better understanding of the sustainability, long-term benefits, and cost-effectiveness of these approaches. The current study will conduct a rigorous evaluation of an existing program, the Common Elements Treatment Approach (CETA) with women (N=300) who are mothers of young children (ages 4-6). The trial will take place in the context of an integrated community care setting in Lima, Peru's most populous and impoverished district, San Juan de Lurigancho. The primary aims are to (1) evaluate the primary and indirect effects of CETA (2) examine moderators of treatment effectiveness, including implementation quality and neighborhood factors and (3) examine CETA's cost effectiveness. The central hypotheses are that (H1a) CETA will improve women's mental health, intimate partner violence, and parenting and that (H1b) CETA will have indirect benefits for women's economic outcomes and for their children's adjustment. It is also hypothesized (H2) that effectiveness will be enhanced by strong implementation quality and the presence of neighborhood promotive factors, and weakened by neighborhood disadvantage. Hypotheses will be evaluated using an RCT employing a longitudinal design with assessments at baseline (T1), post-test (T2), 6-month follow-up (T3) and 12-month follow-up (T4). Women will be randomized into the intervention condition (CETA + Enhanced Case Management \\[ECM\\]) or the comparison condition (ECM). Robust, multi-source (i.e., participant, therapist, supervisor, census data) and multi-method data (i.e., interview, observational assessment, google street view coding) will be gathered. The contribution will be significant by advancing research on both direct and long-term benefits of maternal mental health care for family systems, and is likely to provide important insights into the sustainability and cost effectiveness of these approaches. The expected outcome is an evidence-based, cost-effective, integrated approach to maternal mental health care that can be readily implemented by local organizations. Further, it is anticipated that learnings from this project will respond to broader global public health concerns and provide opportunity for cross-context reciprocal innovation. Expanding the evaluation of CETA delivered in Spanish not only has advantages for the specific context under study, but provides an important foundation for addressing health disparities in Spanish-language mental health services in the US as well.",[58,28,59,60,61,62,63,64],"Violence","Poverty","Depression","Mental Health","Posttraumatic Stress","Economic Factors","Child Psychology","RECRUITING","2026-06-19",{"date":68,"type":36},"2026-06-25",{"date":70,"type":36},"2026-05-18",{"date":72,"type":22},"2030-04-30",{"name":74,"class":75},"University of Notre Dame","OTHER",{"id":77,"slug":78,"hasResults":12,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":12,"sex":51,"minAge":19,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":44},"100546657","navigating-pregnancy-and-parenthood-with-lyme-disease-100546657","NCT06397794","Navigating Pregnancy and Parenthood With Lyme Disease","Mixed Methods Study on Navigating Pregnancy and Parenthood With Lyme Disease","Inclusion Criteria:\n\n* Over 18 years of age and reside in the United States or Canada\n* Diagnosed with acute Lyme disease, PTLDS, and\u002For Chronic Lyme by a health care provider while they were pregnant OR PTLDS\u002FCL prior to becoming pregnant with ongoing symptoms during pregnancy\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Live outside of the United States or Canada\n* Never been diagnosed with Lyme disease by a medical provider\n* Never been pregnant\n* Never given birth to a liveborn infant\n* Previously participated in a qualitative study about their experience with Lyme disease\n* Do not want to agree to having their interviews audio recorded",{"count":84,"type":22},30,"OBSERVATIONAL","This is a mixed methods study exploring the experiences of pregnancy and parenting among participants with Lyme disease. Eligible participants will have been diagnosed with Lyme disease (LD), post-treatment Lyme disease syndrome (PTLDS), and\u002For chronic Lyme (CL) either during or before a prior pregnancy. Participants will complete quantitative surveys on topics such as their medical history, their child(ren)'s development, and demographic information. They will then participate in a qualitative interview where they will be asked about their experiences with pregnancy and with parenting their child(ren) in the context of their condition.",[88,89,90,91,92,93,28],"Lyme Disease","Post Treatment Lyme Disease","Chronic Lyme Disease","Tick-Borne Infections","Tick-Borne Diseases","Pregnancy Complications","2026-06-15",{"date":96,"type":36},"2026-06-17",{"date":98,"type":36},"2024-03-20",{"date":100,"type":22},"2026-12",{"name":102,"class":75},"Children's National Research Institute",{"id":104,"slug":105,"hasResults":12,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":12,"sex":51,"minAge":19,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":23,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":121,"leadSponsor":123,"locationsCount":44},"100598459","improving-outcomes-for-early-postpartum-mothers-in-outpatient-moud-treatment-100598459","NCT07071766","Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment","Adaptation and Implementation of an Evidence-Based Parenting Intervention for Postpartum Women Receiving Medications for Opioid Use Disorder","Inclusion Criteria:\n\n* 18 years or older\n* Understand and speak English\n* Able to give informed consent\n* Receiving medications for opioid use disorder in the outpatient clinical setting\n* Between 28 weeks gestation and up to 12 months postpartum\n\nExclusion Criteria:\n\n* Unwilling to consent\n* Before 28 weeks gestation and beyond 12 months postpartum at enrollment",{"count":111,"type":22},10,[25],"Drug overdose is a leading cause of death among postpartum women and opioid-related mortality is 4 times higher in the postpartum period when compared to the third trimester of pregnancy. Medications for opioid use disorder (MOUD; e.g., methadone or buprenorphine) are the recommended standard of care for perinatal women with OUD. Studies indicate that 50-60% of perinatal women with OUD initiate medications during pregnancy; however, over half will prematurely discontinue treatment within the first six months of childbirth due to stressors experienced in the postpartum period. Common stressors that contribute to MOUD treatment discontinuation in this population are return to opioid use, mental health symptoms including depression, parenting-related stressors such as challenges in infant care and bonding, Neonatal Abstinence Syndrome (NAS), child welfare involvement, and feelings of guilt, shame, and stigma. Thus, there is an urgent need to develop effective, recovery-oriented support interventions that promote the initiation and continuity of MOUD treatment in the postpartum period. The current study utilizes community-engaged research methods to identify and prioritize the early parenting-related needs of postpartum women receiving MOUD to inform the adaptation and implementation of an evidence-based parenting intervention for this population receiving outpatient treatment for opioid use disorder.",[115,116,28],"Substance Use Treatment","Perinatal Substance Use","2026-06-02",{"date":119,"type":36},"2026-06-03",{"date":35,"type":22},{"date":122,"type":22},"2027-06-30",{"name":124,"class":75},"University of Arkansas",{"id":126,"slug":127,"hasResults":12,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":23,"phases":134,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":148,"locationsCount":44},"100438606","a-multimodal-parent-focused-intervention-for-vulnerable-populations-in-the-bronx-100438606","NCT04991467","A Multimodal Parent-focused Intervention for Vulnerable Populations in the Bronx","CARE","Inclusion Criteria:\n\n* All participants will be primary caregivers who present with moderate level of stress by meeting a severity score of ≥ 14 on the Perceived Stress Scale (PSS)\n* Investigators will allow primary caregivers (e.g., grandmothers and aunts) as it is common in the patient population\n* Clinical cohorts will be active patients in the psychiatric and rheumatology clinics in Montefiore Medical Center (MMC)\n* Frontline health care providers will be those who are required to work on site at Montefiore Medical Center (MMC)\n\nExclusion Criteria:\n\n* Serious psychiatric or substance use difficulty that, in the judgement of the PI, would preclude meaningful participation in a parent intervention\n* Active child abuse\u002Fmaltreatment cases\n* Neurocognitive conditions that may prevent participants from accessing telehealth services\n* Primary language other than Spanish or English\n* Use of the Valera Health app or a smartphone health platform similar to the Valera app",{"count":133,"type":22},390,[25],"For caregivers in the Bronx, the pandemic has caused unprecedented psychological distress; in addition to combating social determinants of health (SDOH), these families now face greater financial insecurity and challenges related to their school-aged children. Furthermore, social distancing requirements and limited telehealth resources for Bronx families have posed greater barriers to healthcare. Such parental distress contributes to heightened risk of transgenerational cycles of psychological stress, trauma and maltreatment. The social and economic impacts of the COVID-19 pandemic have had significant consequences for family well-being, putting parents at higher risk of experiencing distress and potentially impairing their ability to provide supportive care to their children. Although children may be less susceptible to the most damaging physical consequences of COVID-19, there are growing concerns regarding the short-and long-term impacts of pandemic-related stressors on children. The marked upheaval of family life over an extended period may make children vulnerable to mental health consequences associated with the public health crisis and infection mitigation efforts. School and childcare closures, unstable financial circumstances, social isolation and lack of support have a disproportionate, cumulative impact on parents and may undermine their capacities to provide support for their children. Importantly, a large body of evidence suggests that parental stress during times of disasters induces psychopathologies in family members including children. Further, high anxiety and depressive symptoms in parents during the pandemic have been associated with higher child abuse potential, whereas greater parental support was associated with lower perceived stress and child abuse potential. In addition to psychological impacts, stress associated with caregiving can interfere with parents' ability to maintain their own health. This multimodal study addresses key strategies to mitigate the psychological and health impact of COVID-19 in parents.",[28,137],"Covid19",[139,140,141,142],"COVID","Parental Stress","Social Determinants of Health","Valera",{"date":144,"type":36},"2026-06-04",{"date":146,"type":36},"2021-12-17",{"date":100,"type":22},{"name":149,"class":75},"Albert Einstein College of Medicine",{"id":151,"slug":152,"hasResults":12,"nctId":153,"briefTitle":154,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":17,"sex":51,"minAge":19,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":23,"phases":159,"briefSummary":160,"conditions":161,"keywords":162,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":44},"100636723","mama-empoderada-parenting-and-mental-health-intervention-100636723","NCT07569393","Mama Empoderada: Parenting and Mental Health Intervention","Mama Empoderada: A Culturally and Linguistically Responsive Preventative Intervention for Spanish Speaking Mothers and Their Young Children","Inclusion Criteria:\n\n1. Identifies as a mother of a child ages 6 or younger;\n2. Spanish-speaker;\n3. available and interested in participating in an in-person or virtual maternal wellbeing and parenting group intervention at La Casa Amiga. Eligibility criteria will be confirmed by each participant through a brief online screening and a phone call with research staff.\n\nExclusion Criteria:\n\n* Participants who are high risk for suicide based on Columbia Suicide Rating Scale",{"count":158,"type":22},20,[25],"This project focuses on the implementation and preliminary evaluation of Mama Empoderada, a brief 12-week group intervention that is based on a parenting program (Mom Power).\n\nThe researcher's hypotheses are that:\n\n1. Participants will show high rates of fidelity, acceptability, and satisfaction with the intervention\n2. Participants will experience decreases in depression, anxiety, isolation, parenting stress, and parent-child interaction problems from pre- to post-intervention, as well as increases in parenting sense of competence.",[28,61],[163,164,165],"Mental health","Group intervention","Spanish","2026-04-28",{"date":168,"type":36},"2026-05-06",{"date":170,"type":22},"2026-04",{"date":172,"type":22},"2026-10",{"name":174,"class":75},"University of Michigan",{"id":176,"slug":177,"hasResults":12,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":17,"sex":18,"minAge":183,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":23,"phases":186,"briefSummary":187,"conditions":188,"keywords":192,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":204},"100541012","phase-2-parenting-in-2-worlds-multisite-trial-100541012","NCT06324318","Parenting in 2 Worlds Multisite Trial","A Multiregional RCT of Parenting in 2 Worlds for Urban American Indian Families","(P2W)","Inclusion Criteria:\n\nAdult participants:\n\n* Must be American Indian parents or guardians of American Indian children aged 12 to 17 who attend urban schools\n* Must reside in the service areas of the four urban Indian centers who are participating in this study\n* Self-identifies as American Indian\n* Must be primary caregiver responsible for day-to-day decisions for an American Indian child ages 12 to 17\n\nChild Participants:\n\n* Aged 12 - 17\n* Identified by their parent\u002Fguardian as American Indian\n* Attends an urban school\n\nExclusion Criteria:\n\n* Not applicable","12 Years",{"count":185,"type":22},1440,[55],"This research study will test the effectiveness of a culturally grounded parenting intervention called Parenting in 2 Worlds (P2W). This intervention is designed for American Indian \u002F Alaska Native (AI) parents\u002Fguardians of adolescents who reside in urban areas. This will be a multi-regional effectiveness trial across four regions: Northeast (Buffalo\u002FNiagara), Midwest (St. Paul\u002FMinneapolis), Mountain (Denver), and Southwest (Phoenix). There are four specific aims. First, this study will test the effectiveness of Parenting in Two Worlds (P2W) as compared to an informational family health intervention, Healthy Families in 2 Worlds (HF2W), in improving parenting and family functioning. Second, this study will test if the relative effectiveness of P2W, compared to HF2W, varies by parent's\u002Fguardian's level of socioeconomic vulnerability, experiences of historical loss, or AI cultural identity. Third, this study will examine if P2W can reduce adolescent (ages 12 - 17) risky health behaviors including substance use, depressive symptoms, suicidality, and risky sexual behaviors. Fourth, this study will examine whether positive changes in parenting and family functioning that result from P2W lead to positive changes in adolescent's health behaviors.",[28,189,190,191],"Mental Health Wellness 1","Substance Use","Risky Health Behavior",[193,194],"family functioning","risky sexual behavior","2026-04-27",{"date":197,"type":36},"2026-04-29",{"date":199,"type":36},"2023-09-14",{"date":201,"type":22},"2028-06-01",{"name":203,"class":75},"Arizona State University",4,{"id":206,"slug":207,"hasResults":12,"nctId":208,"briefTitle":209,"officialTitle":210,"acronym":4,"eligibilityCriteria":211,"healthyVolunteers":12,"sex":18,"minAge":183,"maxAge":212,"enrollmentInfo":213,"targetDuration":4,"studyType":23,"phases":215,"briefSummary":216,"conditions":217,"keywords":220,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":44},"100423713","parent-intervention-for-psychiatrically-hospitalized-youth-100423713","NCT04797455","Parent Intervention for Psychiatrically-Hospitalized Youth","Pilot Intervention for Parents of Psychiatrically-Hospitalized Youth","Inclusion criteria are:\n\n* youth is currently hospitalized on the Stanford unit at Mills Peninsula Medical Center, on the Inpatient Adolescent Psychiatry Unit, for suicidal ideation and\u002For a suicide attempt.\n* youth is between the ages of 12-18 (18 year-old youth must still be in high school and living at home with parents for the duration of the study)\n* at least one parent\u002Fguardian is willing to participate in the study intervention\n* youth and parent speak English well enough to complete study treatment and assessments in English\n\nExclusion criteria are:\n\n• the youth or parent has a psychiatric or medical condition that would interfere with their ability to participate in study assessments and\u002For treatment (such as acute psychosis, neurological impairment, malnutrition due to anorexia)","85 Years",{"count":214,"type":22},40,[25],"The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of a parent coaching intervention for parents of youth hospitalized for suicidal ideation, suicide attempt(s), or non-suicidal self-injury. Parents will receive either the parent coaching intervention (which includes safety planning and behavioral parenting skills training with a clinician and assistance with linkage to follow-up care by a case manager) or treatment as usual (TAU) for the inpatient unit. The long-term goal of the research is to determine if augmenting standard inpatient treatment with additional parenting intervention improves youth treatment response on suicide-related outcomes (i.e., suicidal ideation, non-suicidal self-injury, and suicide attempts). The goal of this pilot RCT is to collect preliminary data needed for a larger RCT, including feasibility, acceptability, safety, tolerability, engagement of the presumed mechanism of change (changes in parent emotions and behaviors), and signal detection of any changes in youth suicide-related outcomes.",[218,219,28],"Adolescent - Emotional Problem","Suicide and Self-harm",[221,222,223],"suicide","Self-Injurious Behavior","Behavioral Symptoms","2026-04-23",{"date":197,"type":36},{"date":227,"type":36},"2023-05-01",{"date":229,"type":22},"2026-06-01",{"name":231,"class":75},"Stanford University",{"id":233,"slug":234,"hasResults":12,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":239,"targetDuration":4,"studyType":23,"phases":241,"briefSummary":242,"conditions":243,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":253,"locationsCount":44},"100579378","thrive-initiative-parent-education-programming-study-100579378","NCT06823518","Thrive Initiative Parent-Education Programming Study","Thrive Initiative Domestic and Chlid Abuse Prevention Programming Study","Inclusion Criteria:\n\n* United States Air Force service member or dependent\n* Parent\u002Fcaregiver of a child 0-18 years old\n* 18 years of age or older\n* Willing to participate in the research study\n* Has access to technology that will enable them to receive and respond to various technological aspects of the Thrive Initiative programs and research study\n* Able to speak and understand English proficiently\n* Able to understand and give consent\n\nExclusion Criteria:\n\n* Not an United States Air Force service member or dependent\n* Not a parent\u002Fcaregiver of a child 0-18 years old\n* 17 years of age or younger\n* Unwilling to participate in the research study\n* Does not have access to technology that will enable them to receive and respond to various technological aspects of the Thrive Initiative programs and research study\n* Unable to speak and understand English proficiently\n* Unable to understand and give consent",{"count":240,"type":22},480,[25],"The purpose of this study is to evaluate the effectiveness of the Thrive Initiative's parent-education program delivery methods by comparing hybrid (i.e., a combination of online and group components) program delivery to online-only program delivery. The Thrive Initiative consists of four, universal parent-education programs that correpsond to specific child developmental periods. These programs inlcude: Take Root for parents\u002Fcaregivers of 0-3-year-old children; Sprout for parents\u002Fcaregivers of 3-5-year-old children; Grow for parents\u002Fcaregivres of 5-10-year-old children; and Branch Out for parents\u002Fcaregivers of 10-18-year-old children. The effectiveness of delivery method will be examined for each program. Eligible participants for this study will be United States Air Force service members or dependents who are caregivers of a child 0-18 years old. The study will involve randomization to condition meaning that participants will be assigned to the online-only or hybrid program delivery condition by chance.",[244,28,245],"Child Maltreatment","Child Wellbeing","2026-04-02",{"date":248,"type":36},"2026-04-08",{"date":250,"type":36},"2026-03-31",{"date":252,"type":22},"2028-12-31",{"name":254,"class":75},"Penn State University",{"id":256,"slug":257,"hasResults":12,"nctId":258,"briefTitle":259,"officialTitle":260,"acronym":4,"eligibilityCriteria":261,"healthyVolunteers":17,"sex":18,"minAge":262,"maxAge":4,"enrollmentInfo":263,"targetDuration":4,"studyType":23,"phases":265,"briefSummary":266,"conditions":267,"keywords":269,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":279,"completionDateStruct":281,"leadSponsor":283,"locationsCount":44},"100529151","chicago-parent-program-for-foster-and-kinship-caregivers-100529151","NCT06170047","Chicago Parent Program for Foster and Kinship Caregivers","The Chicago Parent Program for Foster Care: A Randomized Control Trial Examining the Prevention of Behavior Problems Among Young Children in Foster Care Through Group-based Foster Caregiver Training","Inclusion Criteria:\n\n* Must be a licensed foster caregiver or kinship caregiver to a foster child between the ages of 2 and less than 9 years of age\n* Must be a licensed foster caregiver or kinship caregiver to a foster child in Ohio and in the custody of Hamilton County Job and Family Services, Butler County Children Services, or Montgomery County Children Services\n* Must be in good standing with the foster care agency\n* Must be English-speaking\n\nExclusion Criteria:\n\n* Not having a foster child between the ages of 2 and less than 9 years\n* The foster child not being in the custody of Ohio counties: Hamilton County Job and Family Services, Butler County Children Services, or Montgomery County Children Services\n* The foster child was placed in the home more than 45 days prior to enrollment\n* The foster child being moved out of the placement prior to the start of the intervention\n* The foster child having been previously enrolled with another caregiver\n* The caregiver having been previously enrolled with another child\n* The caregiver unable to commit to completing all study activities\n* The foster child is not enrolled in the study","2 Years",{"count":264,"type":22},300,[25],"The primary objective of this study is to test the effects of an evidence-based prevention intervention (CPP) adapted for foster and kinship caregivers of young children (FC; foster care) on caregiver competence and child behavior problems for children in foster care compared with an active comparator group that receives standard supports through the child welfare and healthcare systems (i.e., usual care).",[268,28],"Behavior Problem",[270,271,272,273,29,274,275],"Foster care","Child behavior","Parenting skills","Behavioral health","Parenting confidence","Parenting stress","2026-03-18",{"date":278,"type":36},"2026-03-19",{"date":280,"type":36},"2024-02-02",{"date":282,"type":22},"2027-08-30",{"name":284,"class":75},"Children's Hospital Medical Center, Cincinnati",{"id":286,"slug":287,"hasResults":12,"nctId":288,"briefTitle":289,"officialTitle":289,"acronym":4,"eligibilityCriteria":290,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":291,"targetDuration":4,"studyType":23,"phases":293,"briefSummary":294,"conditions":295,"keywords":298,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":302,"lastUpdatePostDateStruct":303,"startDateStruct":305,"completionDateStruct":307,"leadSponsor":309,"locationsCount":44},"100524518","delivering-evidence-based-parenting-services-to-families-in-child-welfare-using-telehealth-100524518","NCT06109766","Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth","Inclusion Criteria: Birth parents will be eligible if:\n\n1. they are listed in the official DCYF child welfare database as having an open CPS or FAR intake and a child listed in the case file who is between 6-12 months old,\n2. they speak English,\n3. they are not currently experiencing an acute hospitalization or incarceration,\n4. they have the technological capacity to engage in telehealth, and\n5. they have not had PFR in the past.\n\nExclusion Criteria: Parents will not be eligible if\n\n1. they are experiencing an acute crisis (e.g., hospitalization, incarceration),\n2. they don't have stable enough housing to be able to have home visits,\n3. they don't have reliable access to internet or cell service and\u002For a device with a microphone and camera,\n4. previously received the Promoting First Relationships ® intervention or Child Parent Psychotherapy (CPP).",{"count":292,"type":22},357,[25],"The goal of this randomized controlled trial is to compare Promoting First Relationships - Home Visit (PFR-HV) to Promoting First Relationships - Telehealth (PFR-T) among parents of 6-12 month olds in the child welfare system. The main questions it aims to answer are:\n\n* Is PFR-T effective relative to PFR-HV and Usual Care with respect to observed parent sensitive and responsive care, parent knowledge of child social and emotional development, and child externalizing behavior?\n* Is PFR-T effective relative to PFR-HV and Usual Care with respect to child out-of-home placement in foster care relative to the control group?\n* How does PFR-T compare in a benefit-cost analysis to the cost-effectiveness relative to PFR-HV and Usual Care?\n* Are eligible families impacted by the lack of technology and Wi-Fi\u002Fcellular data to engage in PFR-T?\n* How does provider adherence and fidelity in delivery of PFR-T compare to adherence and fidelity of PFR-HV?\n\nWhat will participants be asked to do?\n\n1. Participants will be asked to agree to randomization, resulting in their placement in one of three groups: PFR-HV, PFR-T, or the control group.\n2. Participants will be asked to participate in three virtual research visits, over the course of approximately 12 months (families could be finished as early as 9 months, however in our experience, intervention sessions and research visits often need to be rescheduled, delaying completion of the study). The research visits take approximately 80 minutes, and families will be paid $75 for each visit they participate in.\n3. During the research visit, the families will be asked to participate in videotaped research activities involving parent-child play and interaction. Parents will be asked to answer questions regarding their background, feelings, parenting opinions, and stress.\n4. Families randomized to the PFR-HV intervention are asked to participate in a 10 week in home parenting program which includes videotaped caregiver-child interactions and feedback.\n5. Families randomized to the PFR-T intervention are asked to participate in a 10-week parenting program that will occur over Zoom, which will include videotaped caregiver-child interactions and feedback.\n6. Families randomized to the control group will be emailed a resource packet with some information about services or programs that might be helpful for them.",[28,296,297,244],"Parent-Child Relations","Child Behavior",[299,300,301],"Telehealth","Fidelity","Cost-Benefit Analysis","2026-03-11",{"date":304,"type":36},"2026-03-16",{"date":306,"type":36},"2023-10-12",{"date":308,"type":22},"2028-04-12",{"name":310,"class":75},"University of Washington",{"id":312,"slug":313,"hasResults":12,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":317,"eligibilityCriteria":318,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":319,"targetDuration":4,"studyType":23,"phases":321,"briefSummary":322,"conditions":323,"keywords":325,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":328,"lastUpdatePostDateStruct":329,"startDateStruct":331,"completionDateStruct":333,"leadSponsor":335,"locationsCount":337},"100531299","resilient-engaged-and-connected-study-100531299","NCT06197997","Resilient, Engaged, and Connected Study","Strengthening Parenting, Young Children's Social-Behavioral Competence, and Kindergarten Readiness in Schools Serving Low-Income Communities","REC","Inclusion Criteria:\n\nPublic school or Community School in Baltimore City, Cecil County, or Harford County serving at least 40% of students meeting eligibility for low-income or located in a community designated as high need by the Maryland State Department of Education based on a score of 0.6 on the Center for Disease Control Social Vulnerability Index:\n\n* has at least 1 full-day public PreK classroom with 20+ students;\n* school has not offered CPP in the prior 3 years;\n* principal consents to being randomized and participate for 2 years;\n* principal consents to study team recruiting parents, teachers, and staff to participate in the study.\n\nPreK Parents:\n\n* Parent (biological, step, adoptive, foster), grandparent, or legal guardian of 4-5 year old student enrolled in participating PreK program;\n* 18+ yrs;\n* speaks English or Spanish;\n* consents to allowing access child's school identification.\n\nTeachers:\n\n* PreK or K teacher in classroom of student of participating parent;\n* consents to completing study surveys.\n\nCPP Group Leaders:\n\n* completes CPP group leader training\n* agrees to lead CPP groups\n* speaks English or Spanish\n* at least a High School diploma\u002FGeneral Equivalency Diploma (GED)\n* consents to completing surveys and submitting audio recorded CPP sessions for fidelity assessment\n\nSchool-based personnel inclusion criteria:\n\n* Principal, teacher, or other school-based staff involved in CPP implementation\n* consents to interview on perspectives about CPP in the school\n\nExclusion Criteria:\n\n* Principal cannot commit staff to offering CPP groups\n* school previously offered CPP in prior 3 years\n* school located in a geographic area with less than 80% connectivity\n* PreK Parents previously participated in CPP\n* Teachers: teacher also a participating parent or CPP group leader\n* School-based personnel: Principal, teacher, or other school-based staff is a study parent",{"count":320,"type":22},840,[25],"Purpose of this study is to test the effectiveness and implementation of an evidence-based parenting intervention for improving parenting and school outcomes in a sample of 4-5-year-old children enrolled in public prekindergarten (PreK) programs in Maryland.",[28,324],"Parenting Intervention",[28,326,327],"Chicago Parent Program","CPP","2026-03-06",{"date":330,"type":36},"2026-03-09",{"date":332,"type":36},"2024-09-01",{"date":334,"type":22},"2028-06-30",{"name":336,"class":75},"Johns Hopkins University",2,{"id":339,"slug":340,"hasResults":12,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":4,"eligibilityCriteria":344,"healthyVolunteers":17,"sex":18,"minAge":345,"maxAge":4,"enrollmentInfo":346,"targetDuration":4,"studyType":23,"phases":347,"briefSummary":348,"conditions":349,"keywords":351,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":354,"lastUpdatePostDateStruct":355,"startDateStruct":357,"completionDateStruct":359,"leadSponsor":361,"locationsCount":337},"100606054","relationship-enhancement-digital-game-100606054","NCT07170553","Relationship Enhancement Digital Game","Digital Game Intervention for Relationship Enhancement Among Parent Child Dyads","Inclusion Criteria:\n\n* Caregiver-child dyads.\n\nExclusion Criteria:\n\n* Participant is not part of a caregiver- child dyad.","6 Years",{"count":84,"type":22},[25],"The purpose of this study is to test a new digital game. Specifically, this study will aim to evaluate a digital game prototype designed to facilitate playful interactions between parents and children. The prototype will incorporate activities grounded in relationship enhancement principles. Additionally, this study will check how well using digital tools helps build strong connections, makes people get along better, and boosts parents' confidence and parenting skills.",[296,28,350],"Attachment Disorder",[352,353],"Digital Intervention","Attachment Based","2026-02-27",{"date":356,"type":36},"2026-03-03",{"date":358,"type":22},"2026-06",{"date":360,"type":22},"2027-04-30",{"name":362,"class":75},"University of Miami",{"id":364,"slug":365,"hasResults":12,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":369,"eligibilityCriteria":370,"healthyVolunteers":17,"sex":18,"minAge":371,"maxAge":372,"enrollmentInfo":373,"targetDuration":4,"studyType":23,"phases":375,"briefSummary":376,"conditions":377,"keywords":380,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":384,"lastUpdatePostDateStruct":385,"startDateStruct":387,"completionDateStruct":389,"leadSponsor":391,"locationsCount":44},"100575054","i-interact-preterm-parenting-100575054","NCT06767293","I-InTERACT Preterm Parenting","I-InTERACT Preterm Parenting Randomized Controlled Trial","I2P-RCT","Inclusion Criteria:\n\n* Born at \\\u003C 32 weeks gestational age.\n* Total T score of \\> 55 on the Child Behavior Checklist Total or Externalizing Behavior Scales OR Total T score of \\> 55 on the Eyberg Child Behavior Inventory total problem- or total intensity-scale.\n* English is the primary spoken language in the home.\n\nExclusion Criteria:\n\n* Is not 18 years or older.\n* Participant will be excluded from the study if the child does not reside with the caregiver at least half-time; the caregiving situation is not stable (i.e., there must be no scheduled custody hearings).\n* English is not the primary language spoken in the home.\n* Caregivers with a psychiatric hospitalization in the past year.","3 Years","8 Years",{"count":374,"type":22},90,[25],"Many children born very preterm experience behavior problems, and existing resources for parenting these children are lacking. A pilot trial established the effectiveness of a preterm parenting intervention, I-Interact Preterm (I2P). This study proposes a three-arm randomized controlled trial (RCT) comparing the established seven-session I2P program, a microlearning delivery mode (I2P-Micro), and an internet resource comparison group (IRC). Outcomes will be assessed at pretreatment, post-treatment (12 weeks later), and at an extended follow-up six months post-randomization. These outcomes include parenting behaviors, child behavior problems, and parent distress. It is anticipated that both I2P and I2P-Micro will result in significant improvements relative to the IRC condition, with greater utilization expected in the I2P-Micro group.",[378,379,296,28],"Child Behavior Problem","Preterm",[381,382,383],"telehealth","online learning","microlearning","2026-02-05",{"date":386,"type":36},"2026-02-09",{"date":388,"type":36},"2024-11-27",{"date":390,"type":22},"2027-09-30",{"name":284,"class":75},{"id":393,"slug":394,"hasResults":12,"nctId":395,"briefTitle":396,"officialTitle":397,"acronym":4,"eligibilityCriteria":398,"healthyVolunteers":17,"sex":51,"minAge":19,"maxAge":4,"enrollmentInfo":399,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":401,"conditions":402,"keywords":405,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":407,"lastUpdatePostDateStruct":408,"startDateStruct":410,"completionDateStruct":411,"leadSponsor":413,"locationsCount":44},"100621880","association-of-spousal-support-with-parenting-self-confidence-and-depression-in-primipar-mothers-100621880","NCT07376369","Association of Spousal Support With Parenting Self-Confidence and Depression in Primipar Mothers","Primipar Annelerde Eş Desteğinin Doğum Sonu Ebeveynlik Özgüveni ve Depresyon Düzeyleri Üzerindeki Etkisi: Kesitsel Bir Çalışma","Inclusionsd Criteria:\n\n* Aged 18 years or older\n* Primiparous mothers (first childbirth)\n* Between 0 and 12 months postpartum\n* Living with spouse or partner\n* Able to read and write Turkish\n* Having access to the internet\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Diagnosed neurological disorder\n* Diagnosed psychiatric disorder\n* Visual impairment preventing completion of questionnaires\n* Cognitive impairment preventing completion of questionnaires",{"count":400,"type":22},193,"The transition to motherhood, particularly for first-time (primiparous) women, is a critical life period requiring substantial psychological and social adjustment. Hormonal changes, increased caregiving responsibilities, sleep disturbances, and potential social isolation during pregnancy and the postpartum period may increase vulnerability to stress, anxiety, and depressive symptoms. Postpartum depression (PPD) is a common mental health concern that adversely affects maternal well-being, mother-infant interaction, and infant development, with insufficient social support identified as one of its most significant risk factors.\n\nMaternal self-efficacy, defined as a mother's perceived competence in caring for and responding to her infant's needs, is a key indicator of successful adaptation to the parenting role. Evidence suggests that maternal self-efficacy develops primarily within the first months after childbirth and tends to be lower in primiparous women. Low parenting self-efficacy has been associated with increased depressive symptoms, higher parenting stress, impaired mother-infant bonding, and negative developmental outcomes for the infant.\n\nAmong social support sources, partner support plays a particularly protective role during the transition to parenthood. Emotional, informational, and practical support provided by the partner has been shown to enhance maternal self-efficacy, reduce psychological distress, improve marital adjustment, and lower the risk of postpartum depression. Conversely, low perceived partner support and relationship difficulties are associated with an increased risk of PPD in primiparous mothers.\n\nThe aim of this study is to examine the relationship between perceived partner support and postpartum parenting self-efficacy and depressive symptoms in primiparous women. Additionally, the study seeks to evaluate the explanatory and protective role of partner support on maternal self-efficacy and postpartum depression during the early postpartum period.",[403,404,28],"Support","Postpartum Period",[404,403,28,406],"Primipar","2026-01-30",{"date":409,"type":36},"2026-02-03",{"date":407,"type":36},{"date":412,"type":22},"2027-01",{"name":414,"class":75},"Istanbul University - Cerrahpasa",{"id":416,"slug":417,"hasResults":12,"nctId":418,"briefTitle":419,"officialTitle":420,"acronym":421,"eligibilityCriteria":422,"healthyVolunteers":17,"sex":18,"minAge":372,"maxAge":4,"enrollmentInfo":423,"targetDuration":4,"studyType":23,"phases":425,"briefSummary":426,"conditions":427,"keywords":429,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":407,"lastUpdatePostDateStruct":432,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":437,"locationsCount":44},"100559835","filipino-family-health-initiative-10-100559835","NCT06569303","Filipino Family Health Initiative 1.0","Virtual Positive Parenting Intervention to Promote Filipino Family Wellness: A Randomized Controlled Trial : Filipino Family Health Initiative 1.0","FFHI","Inclusion Criteria:\n\n* Parent or legal guardian of at least one child 8-12 years of age\n* Parent or legal guardian is of Filipino descent\n* Parent or legal guardian and child are English speaking\n* Pregnant women or legal guardians may be included if they have a child who meets the inclusion and exclusion criteria\n\nExclusion Criteria:\n\n* Family plans to move out of the state of California within the next 6 months\n* Family has previously participated in the Incredible Years (IY) curriculum\n* Parent or legal guardian are not fluent in English\n* Adults unable to consent or children unable to assent\n* Prisoners\n\nNote: All parent participants in the study are 18 years or older. Youth participants are 8-12 years old.",{"count":424,"type":22},500,[25],"The goal of this clinical trial is to test the effectiveness of an online parenting program on Filipino parents living in California. The main aims are to:\n\n* Test the effectiveness of the online Incredible Years® model of parent training and its impact on primary outcomes.\n* Determine the impact of intervention engagement (i.e., higher attendance) on parenting practices and child behavior outcomes.\n* Describe Intervention delivery and its online implementation in real-world community settings.\n\nThe study involves two phases:\n\n* Phase 1: Participants will receive the Online Incredible Years® School Age Basic \\& Advanced Parent Training Program (intervention) and complete parent-reported and child-reported measures at baseline, 3 months and 6 months.\n* Phase 2: Parenting Group Leaders will each participate in one semi-structured interview to inform the sustainability of the intervention in real world community settings. Researchers will compare 250 Filipino families, half of which will receive the intervention and the other half will receive the American Academy of Pediatrics' Bright Futures handouts (control) and be placed on a 3-month waitlist for the IY parenting program. Both groups will be followed for a minimum of 6 months with follow- up assessments that include parent-report and child report measures.",[60,428,28],"Anxiety",[430,431,61],"Filipino Families","Incredible Years",{"date":409,"type":36},{"date":434,"type":36},"2025-04-15",{"date":436,"type":22},"2028-03-31",{"name":438,"class":75},"Kaiser Permanente",{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":12,"sex":18,"minAge":262,"maxAge":183,"enrollmentInfo":446,"targetDuration":4,"studyType":23,"phases":447,"briefSummary":448,"conditions":449,"keywords":450,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":453,"lastUpdatePostDateStruct":454,"startDateStruct":456,"completionDateStruct":458,"leadSponsor":460,"locationsCount":337},"100470023","natural-helpers-and-pcit-100470023","NCT05400434","Natural Helpers and PCIT","The Development and Implementation of a Natural Helpers Program to Increase the Recruitment, Retention, and Engagement of Underserved Families in Parent-Child Interaction Therapy (PCIT)","Inclusion Criteria:\n\n1. Families of children 2 years of age to 12 years of age.\n2. Children 2 to 7 years of age with a history of child abuse or neglect and\u002For child behavior problems or children ages 8 years to 12 years of age with history of or risk for abuse and the child does not exhibit clinically significant behavior problems.\n3. At the time of enrollment, participants must agree that, within the upcoming six months, they will not move away to a location where they would no longer be able to regularly attend weekly sessions (i.e., moving out of Miami Dade County).\n\nExclusion Criteria:\n\n1. Families with child younger than 2 years of age or older than 7 years of age with clinically significant behavior problems\n2. Adults who are unable to consent and prisoners",{"count":264,"type":22},[25],"The purpose of the study is to evaluate the effect of a time-limited (i.e., 18 weeks) community health worker (CHW) intervention, referred to as the Parent Child Interaction Therapy (PCIT) plus natural helper (NH) model, on treatment engagement, retention, and child and caregiver outcomes.",[297,28],[451,452],"Community Health Workers","Mental Health Disparities","2026-01-11",{"date":455,"type":36},"2026-01-13",{"date":457,"type":36},"2018-12-03",{"date":459,"type":22},"2026-12-27",{"name":362,"class":75},{"id":462,"slug":463,"hasResults":12,"nctId":464,"briefTitle":465,"officialTitle":466,"acronym":4,"eligibilityCriteria":467,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":468,"targetDuration":4,"studyType":23,"phases":470,"briefSummary":471,"conditions":472,"keywords":477,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":484,"lastUpdatePostDateStruct":485,"startDateStruct":487,"completionDateStruct":489,"leadSponsor":490,"locationsCount":44},"100619222","parental-support-intervention-in-an-advanced-oncological-context-100619222","NCT07341815","Parental Support Intervention in an Advanced Oncological Context","Efficacy of a Parental Support Intervention to Improve Communication of Advanced Cancer Patients With Adolescents and Young Adults","Inclusion Criteria:\n\n* Metastatic cancer, recurrence of cancer or certain types of hematological cancer (chronic disease, acute leukemia, multiple myeloma or lymphoma recurrence)\n* Have at least one child aged between 10 and 25 years\n* Wish to benefit from a psychological intervention about communication with their children about cancer or its consequences\n* Able to read and speak French\n* Accept to give their written informed consent\n\nExclusion Criteria:\n\n* Severe neurological disorder\n* Severe psychiatric disorder\n* (Pre-)terminal phase of cancer disease",{"count":469,"type":22},120,[25],"This prospective, two-arm randomized trial compares a psycho-educational program to a psycho-educational and experiential program for parents with advanced cancer. These two interventions aim to support parent-child communication about cancer, but we hypothesize that the combined intervention will be more effective for all studied communication variables.",[473,474,475,296,28,476],"Metastatic Cancer","Cancer Recurrence","Hematological Cancer","Communication",[478,479,480,481,482,483],"Parental cancer","Parent-child communication","Parenting intervention","Advanced cancer","Adolescent Young Adult (AYA)","Uncertainty","2026-01-07",{"date":486,"type":36},"2026-01-14",{"date":488,"type":36},"2022-05-27",{"date":100,"type":22},{"name":491,"class":75},"Université Libre de Bruxelles",{"id":493,"slug":494,"hasResults":12,"nctId":495,"briefTitle":496,"officialTitle":497,"acronym":498,"eligibilityCriteria":499,"healthyVolunteers":12,"sex":51,"minAge":19,"maxAge":500,"enrollmentInfo":501,"targetDuration":4,"studyType":23,"phases":502,"briefSummary":503,"conditions":504,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":509,"completionDateStruct":511,"leadSponsor":513,"locationsCount":44},"100557625","moms-managing-attention-deficithyperactivity-disorder-adhd-study-100557625","NCT06540547","Moms Managing Attention-Deficit\u002FHyperactivity Disorder (ADHD) Study","Supporting Expectant Mothers With ADHD Through the Transition to Parenthood","MomMA","Inclusion Criteria:\n\n* (1) meet full DSM-5 criteria for ADHD\n* (2) are between 20- and 32-weeks of gestation\n* (3) speak English\n* (4) will deliver at the University of Pittsburgh Medical Center (UPMC) Magee Women's Hospital (MWH)\n\nExclusion Criteria:\n\n* (1) active substance use disorder\n* (2) intellectual disability\n* (3) other severe mental illness, including bipolar disorder, psychosis, and major depressive disorder with suicidal ideation or requiring higher level of care (inpatient or partial\u002Fintensive outpatient)\n* (4) high risk pregnancies requiring transfer of care to Maternal-Fetal Medicine (e.g., maternal cancer, multiples, placenta accreta) and\u002For fetus known to have a severe congenital condition.","55 Years",{"count":111,"type":22},[25],"The study will develop and test a behavioral program for pregnant individuals with Attention-Deficit\u002FHyperactivity Disorder (ADHD). This behavioral program will include skills for managing ADHD and related symptoms during pregnancy and after delivery and will be taught by a behavioral therapist in OB care settings.",[505,28],"ADHD","2026-01-06",{"date":508,"type":36},"2026-01-08",{"date":510,"type":36},"2025-01-19",{"date":512,"type":22},"2026-07-31",{"name":514,"class":75},"University of Pittsburgh",{"id":516,"slug":517,"hasResults":12,"nctId":518,"briefTitle":519,"officialTitle":519,"acronym":4,"eligibilityCriteria":520,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":521,"enrollmentInfo":522,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":524,"conditions":525,"keywords":526,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":528,"lastUpdatePostDateStruct":529,"startDateStruct":531,"completionDateStruct":533,"leadSponsor":535,"locationsCount":44},"100527262","parenting-for-tomorrow-a-new-model-for-supporting-preschool-childrens-mental-health-in-head-start-100527262","NCT06145477","Parenting for Tomorrow: A New Model for Supporting Preschool Children's Mental Health in Head Start","Inclusion Criteria:\n\n* Child is 2-5 years old, enrolled in Baltimore City Head Start (Baltimore City Mayor's Office on Child \\& Family Success) or Head Start sites managed by Catholic Charities of MD\n* parent expresses concern about the child's behavior or need for parenting support\n* parent speaks English or Spanish\n* Parent age 18-99 years\n* Parent able to participate in virtual intervention sessions\n\nExclusion Criteria:\n\n* Parent does not speak English or Spanish","99 Years",{"count":523,"type":22},160,"Purpose of this study is to test the preliminary efficacy, acceptability, accessibility, cost, and sustainability of an innovative mental health treatment model for young children from low-income, under-resourced communities through a partnership with Head Start programs in urban and rural communities in Maryland.",[28,324],[28,326,527],"CPPi","2025-12-11",{"date":530,"type":36},"2025-12-12",{"date":532,"type":36},"2023-11-15",{"date":534,"type":22},"2028-11",{"name":336,"class":75},{"id":537,"slug":538,"hasResults":12,"nctId":539,"briefTitle":540,"officialTitle":541,"acronym":4,"eligibilityCriteria":542,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":543,"enrollmentInfo":544,"targetDuration":4,"studyType":23,"phases":546,"briefSummary":547,"conditions":548,"keywords":550,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":555,"lastUpdatePostDateStruct":556,"startDateStruct":558,"completionDateStruct":560,"leadSponsor":562,"locationsCount":44},"100334953","centeringparenting-clinical-intervention-on-kindergarten-readiness-in-early-childhood-100334953","NCT03641092","CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood","Evaluation of the Impact of the CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood","Inclusion Criteria:\n\nFor participating practice sites\n\n* Practice provides care to patients who are covered by public insurance and\u002For uninsured (no minimum threshold: all insurance types eligible)\n* Practices have at least 3,000 primary care visits per year\n\nFor parent-child dyad\n\n* Index child age must be 0-3 months\n* Parent must be female\n* Parent must be 18 years of age and older\n* Parent and child must attend one of the 10 study clinical sites\n* Parental consent\n* Parent must be fluent in English or Spanish\n\nExclusion Criteria:\n\nFor participating practice sites\n\n* Does not accept public insurance\n\nFor parent-child dyad\n\n* Child born prior to 34 weeks gestation\n* Child with chronic conditions known to affect neurodevelopment\n* Child with a positive screen on the Children with Special Healthcare Needs screener","3 Months",{"count":545,"type":22},1200,[25],"Disparities in health begin in early childhood. Early life experiences influence brain development and have significant implications on future health and developmental outcomes. Low-income children are at greater risk of developmental delays in large part due to a lack of an enriched environment. Disparities in early childhood development increase risk for stunted academic achievement throughout the life course. Primary care is a universal exposure in early childhood and therefore is also a significant entry point for promoting optimal child development.\n\nThere is a need to provide effective, low-cost, and scalable interventions in primary care to support early childhood development.The CenteringParenting intervention is designed to reduce negative health and developmental outcomes within a model of group routine child health care. To date, there is no evidence of the benefits of the CenteringParenting intervention on school readiness, or improvements in parental behaviors that support optimal developmental milestones and achievement. The intent of this study is to determine the effectiveness of the CenteringParenting intervention on school readiness in early childhood, as measured by language development at 24 months, (in addition to health care utilization, child routine care maintenance, parenting stress, caregiver behaviors and attitudes).",[296,28,549,297],"Child Development",[551,552,271,553,554],"School readiness","Child development","Parenting behavior","CenteringParenting","2025-11-26",{"date":557,"type":36},"2025-12-01",{"date":559,"type":36},"2019-02-19",{"date":561,"type":22},"2026-09",{"name":563,"class":75},"Boston Medical Center",{"id":565,"slug":566,"hasResults":12,"nctId":567,"briefTitle":568,"officialTitle":569,"acronym":4,"eligibilityCriteria":570,"healthyVolunteers":17,"sex":18,"minAge":571,"maxAge":572,"enrollmentInfo":573,"targetDuration":4,"studyType":23,"phases":575,"briefSummary":576,"conditions":577,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":581,"lastUpdatePostDateStruct":582,"startDateStruct":584,"completionDateStruct":586,"leadSponsor":588,"locationsCount":337},"100524615","nurturing-needs-study-parenting-food-motivated-children-100524615","NCT06111040","Nurturing Needs Study: Parenting Food Motivated Children","Deconstructing Food Parenting Approaches to Obesity Prevention for the Highly Food Motivated Child","Inclusion Criteria:\n\n1. Child ages 4 or 5 years at baseline;\n2. Parent\u002F primary caregiver with legal representation (having 50% or more custody of child);\n3. Parent\u002Fprimary caregiver reporting primary responsibility for child feeding outside of childcare (being with child when they are eating at least two times daily);\n4. Caregiver with a cell phone that can be used to send and receive text messages. If there is more than one age-eligible child in the family, we will ask the caregiver to pick the index child.\n\nExclusion Criteria:\n\n1. Parent\u002Fprimary caregiver \\\u003C18 years of age;\n2. Child history of major food allergies (e.g., peanuts);\n3. Child medication use (e.g., insulin), developmental disability (e.g., autism) or medical condition(s) (e.g., diabetes) known to affect food intake and growth;\n4. Foster child.","4 Years","5 Years",{"count":574,"type":22},416,[25],"High food motivation among children is trait-like and increases risks of unhealthy dietary intake and obesity. Scientific knowledge of how parenting can best support healthy eating habits and growth among children who are predisposed to overeating is surprisingly limited. This investigation will identify supportive food parenting approaches for obesity prevention that address the needs of highly food motivated children.",[28,578,579,580],"Eating Behavior","Diet, Healthy","Pediatric Obesity","2025-11-03",{"date":583,"type":36},"2025-11-05",{"date":585,"type":36},"2023-09-07",{"date":587,"type":22},"2027-10-31",{"name":589,"class":75},"Temple University",{"id":591,"slug":592,"hasResults":12,"nctId":593,"briefTitle":594,"officialTitle":594,"acronym":4,"eligibilityCriteria":595,"healthyVolunteers":12,"sex":18,"minAge":596,"maxAge":597,"enrollmentInfo":598,"targetDuration":4,"studyType":23,"phases":600,"briefSummary":601,"conditions":602,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":606,"lastUpdatePostDateStruct":607,"startDateStruct":609,"completionDateStruct":611,"leadSponsor":613,"locationsCount":44},"100519067","unified-protocol-community-connections-100519067","NCT06038721","Unified Protocol: Community Connections","Inclusion Criteria:\n\n* Children between the ages of 7-17.\n* Youth currently resides in Miami-Dade County.\n* Children and their parents must be able to speak and understand English and\u002For Spanish sufficiently well to complete study procedures (e.g., provide their informed consent\u002Fassent, complete assessment measures and\u002For program materials).\n* At least one parent or caregiver with whom the child is living with that can accompany the child and participate in all visits (assessment and treatment).\n* Positive endorsement of elevated emotional concerns in one of a limited range of emotional disorder domains (i.e., anxiety, depression, trauma, or obsessive-compulsive symptoms, etc.) during full DIAMOND-Kid semi-structured interview, and\u002For elevated anxiety or depression symptoms (T-Score \\> or = 65 for youth 8-17 years old; Raw score \\> or = 12 for children under 8 years old) on the Revised Child Anxiety and Depression Scale - Short Form (RCADS-SF; Child or Parent Report).\n* Youth with other types of comorbid conditions (e.g., tic\u002FTourette's disorder, eating disorders, or disruptive behavior disorders) will not be excluded, providing a clinical area of concern is regarding one of the emotional disorder domains specified and treatment within this protocol is deemed most appropriate.\n* Youth and parent participation in at least one in-person session if the treatment is predominantly delivered virtually.\n\nExclusion Criteria:\n\n* Prior receipt of at least 8 sessions of the UP-C\u002FA program at the Child and Adolescent Mood and Anxiety Treatment Program (CAMAT).\n* Psychiatric hospitalization in the previous 6 months (i.e., due to Baker Act, psychotic symptoms, significant suicidal ideation, danger to self or others, etc.).\n* Another significant problem area that takes priority for services (e.g., eating disorder, substance-use disorder, primary externalizing concerns, psychotic symptoms, etc.), as identified by family report or via DIAMOND-Kid interview.\n* Inability for family to wait for the next group treatment cohort to start, family declining therapist assignment following intake, and\u002For family no-showing to 3 or more scheduled sessions at CAMAT (inclusive of intake assessment).","7 Years","17 Years",{"count":599,"type":22},1500,[25],"The purpose of this study is to administer the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) and Adolescents (UP-A) to youth and participants' parents and to examine the efficacy and outcomes of the treatment using standardized measures, questionnaires, interviews. The UP-C and the UP-A are cognitive-behavioral therapies to treat emotional disorders.",[603,604,605,28],"Mental Health Issue","Anxiety Disorder","Depressive Disorder","2025-09-09",{"date":608,"type":36},"2025-09-11",{"date":610,"type":36},"2023-09-25",{"date":612,"type":22},"2028-09-25",{"name":362,"class":75},{"id":615,"slug":616,"hasResults":12,"nctId":617,"briefTitle":618,"officialTitle":619,"acronym":620,"eligibilityCriteria":621,"healthyVolunteers":17,"sex":18,"minAge":371,"maxAge":572,"enrollmentInfo":622,"targetDuration":4,"studyType":23,"phases":624,"briefSummary":625,"conditions":626,"keywords":628,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":632,"lastUpdatePostDateStruct":633,"startDateStruct":634,"completionDateStruct":636,"leadSponsor":638,"locationsCount":44},"100410661","project-peak-early-intervention-for-adhd-100410661","NCT04627415","Project PEAK: Early Intervention for ADHD","Early Intervention for Young Children At-Risk for ADHD: Evaluating Efficacy and Delivery Format for Behavioral Parent Education","PEAK","Inclusion Criteria:\n\n* 3- to 5.11-year old children with clinically significant symptoms of ADHD.\n* Children had to have met DSM-5 criteria for one of the three presentations of ADHD based on clinical interview and parent and teacher behavior ratings, including parent and teacher report of elevated levels of impairment at home and school (i.e., score greater than 90th percentile on one or more Conners Early Childhood Rating Scale subscales relevant to ADHD).\n\nExclusion Criteria:\n\n* A diagnoses of autism spectrum disorder (ASD), pervasive developmental disorder, intellectual disability, neurological damage, or significant motor or physical impairments.\n* Children needed to be enrolled in a pre-school or day care setting at least 2 days a week unless otherwise unable to enroll (e.g. behavioral problems, lack of services for unrelated disability) in order to establish the presence of symptoms across two settings.",{"count":623,"type":22},180,[25],"Parent education is an effective and relatively cost efficient approach for reducing child behavior problems. Research, however, suggests that the effectiveness of parent education is mitigated by parent attendance and parent implementation of intervention strategies. That is, low attendance at parent education sessions is associated with limited intervention effects. Therefore, it is critical to identify strategies to enhance parent engagement. A previous pilot randomized controlled trial of a parent education program (Behavioral Parent Education; BPE, specifically Promoting Engagement for ADHD pre-Kindergartners \\[PEAK\\]), found that both face-to-face (F2F) and online BPE resulted in high levels of parent engagement and child behavior improvements. However, results need to be replicated in a full scale efficacy trial with a larger, diverse sample to provide more reliable estimates of relative effect sizes for parent and child outcomes and to evaluate the extent to which parent and child behavior changes are maintained after BPE has ended. In the current randomized controlled trial, the investigators intend to apply What Works Clearinghouse group design standards to examine the efficacy of two forms of delivery of BPE (F2F and online) relative to a wait-list control condition in a sample of 180, 3- to 5-year old children with clinically significant symptoms of ADHD. The objective is to: (a) extend findings from the pilot investigation to a large, diverse sample; (b) examine maintenance of effects; (c) identify moderators and mediators of treatment outcome, especially the degree to which these may differ for F2F vs. online treatment delivery; and (d) assess cost and cost-effectiveness of the two PEAK delivery formats.",[627,296,297,28],"Attention Deficit Hyperactivity Disorder",[505,629,630,631],"Behavioral Parent Training","Early Intervention","Preschool","2025-09-02",{"date":606,"type":36},{"date":635,"type":36},"2020-09-01",{"date":637,"type":22},"2026-12-31",{"name":639,"class":75},"Lehigh University",{"id":641,"slug":642,"hasResults":12,"nctId":643,"briefTitle":644,"officialTitle":645,"acronym":646,"eligibilityCriteria":647,"healthyVolunteers":17,"sex":18,"minAge":648,"maxAge":649,"enrollmentInfo":650,"targetDuration":4,"studyType":23,"phases":652,"briefSummary":653,"conditions":654,"keywords":655,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":657,"lastUpdatePostDateStruct":658,"startDateStruct":660,"completionDateStruct":662,"leadSponsor":663,"locationsCount":44},"100529884","connect-to-baby-a-pilot-study-of-a-parenting-and-coparenting-program-100529884","NCT06179576","Connect to Baby: A Pilot Study of a Parenting and Coparenting Program","Connect to Baby: A Pilot Study of a Parenting and Coparenting Program for New Parents","CTB","Inclusion Criteria:\n\n* Must be a mother, father (or father figure, including same sex parent and grandparent) of an infant who is 2-24 months.\n* Must speak and read English or Spanish with sufficient fluency for completion of consent forms and questionnaires and actively participate in the intervention.\n\nExclusion Criteria:\n\n• Pre-intervention assessment their score on the Woman Abuse Screening Tool (WAST) Interpersonal Violence (IPV) screener (Brown, Lent, Schmidt, \\& Sas, 2000) indicates sexual or physical abuse.","2 Months","40 Years",{"count":651,"type":22},200,[25],"The proposed project is a randomized control trial to assess a novel 6-session parenting and coparenting intervention for low-income parents of infants. Connect to Baby (CTB) will be implemented within one of the largest federally-funded early care and education programs, Early Head Start (EHS), in Washington, DC. To engage both fathers and mothers, CTB recruits parents at the time of birth, capitalizing on the \"magic moment\" of delivery, and uses father-inclusive digital media content to engage men. A key innovation lies in the introduction and rehearsal of four interaction skills -- Noticing, Following, Talking, and Encouraging (NiFTE, pronounced \"Nifty\") -- to foster serve-and-return interactions with infants as well as supportive, cooperative coparenting interactions between mothers and fathers. To maximize program uptake, CTB is situated within an early education program parents already trust and attend. Additionally, the study will test hybrid program delivery with both in-person and remote sessions using video-enabled tablets to reduce scheduling and logistical barriers and thereby enhance retention. The specific aims of the project are to assess efficacy of random assignment to Hybrid delivery of CTB relative to EHS as usual at enhancing parenting and coparenting quality and parent and child wellbeing. If demonstrated to be efficacious, this program will provide Early Head Start (and other family-serving agencies) a brief cost-effective, manualized preventive intervention that could be used alone or in conjunction with other services to improve parent functioning and co-parenting, further engage fathers in programming and caregiving, and, ultimately, enhance child development.",[28],[656],"Parent Education","2025-08-18",{"date":659,"type":36},"2025-08-19",{"date":661,"type":36},"2023-08-01",{"date":250,"type":22},{"name":664,"class":75},"Georgetown University"]