[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parkinson-disease-mild-cognitive-impairment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parkinson-disease-mild-cognitive-impairment":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100565322","electrophysiological-signature-of-mild-cognitive-impairment-and-its-relationship-with-parkinsons-disease-a-high-density-eeg-investigation-100565322",false,"NCT06640673","Electrophysiological Signature of Mild Cognitive Impairment and Its Relationship with Parkinson's Disease: a High-density EEG Investigation","MMCI","Inclusion Criteria:\n\n* Upper score \\>24 MMSE or \\>15.5 Moca\n* If taking medications, taking stable doses for at least 4 weeks prior to the inclusion visit - of anticholinesterase drugs (donepezil, memantine, rivastigmine, ...) or antidepressants (SSRIs, tricyclics, SNARI, ...) or Levodopa.\n* Having signed the informed consent\n\nExclusion Criteria:\n\n* Subjects with severe dementia ( MMSE \\\u003C 24 )\n* Lower score \\\u003C15.5 Moca\n* Subjects on antipsychotic treatment for less than 3 months\n* Subjects with uncontrolled comorbidities\n* Subjects with metal prostheses or dentures and in general conditions for which MRI examinations are prevented.\n* Subjects with an inability to walk independently.",true,"ALL","50 Years","90 Years",{"count":21,"type":22},42,"ESTIMATED","OBSERVATIONAL","The study aims to investigate neural correlate of Mild Cognitive Impairment (MCI) in Parkinson's disease (PD) and to identify a link between functional impairment (in both cognitive and motor domains) and electrophysiological cortical sing of MCI in PD. A sample of 42 subjects will be divide into three subgroup: healthy control, PD with MCI (PD-MCI) and PD without MCI (PD-ctrl). Those subjects will undergo a specific neuropsychological evaluation and, to measure the electro-cortical activity, high-density electroencephalography (hdEEG) will be record during both resting state and cognitive tasks. Furthermore, hdEEG data will be combine with structural magnetic resonance to obtain information about network connectivity.",[26,27,28],"Parkinson Disease","Parkinson Disease, Mild Cognitive Impairment","Healthy",[30,31,32,33],"MCI in PD","Mild Cognitive Impairment","Parkinson's disease","Hd-EEG","RECRUITING","2024-10-11",{"date":37,"type":38},"2024-10-15","ACTUAL",{"date":40,"type":38},"2023-06-18",{"date":42,"type":22},"2025-05",{"name":44,"class":45},"IRCCS San Camillo, Venezia, Italy","OTHER"]