[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parkinsons-disease-with-mild-cognitive-impairment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parkinsons-disease-with-mild-cognitive-impairment":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100627475","effect-of-striatal-temporal-interference-stimulation-on-language-processing-in-neurodegenerative-diseases-100627475",false,"NCT07449117","Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases","Immediate Effects of Non-invasive Temporal Interference Stimulation Targeting Deep Fronto-Striatal Structures on Language Processing and Behavioral Performance in Patients With Neurodegenerative Diseases","Inclusion Criteria:\n\n* Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).\n\nExclusion Criteria:\n\n* Any severe psychiatric disorder.\n* History of other neurological diseases affecting the central nervous system.\n* Severe head trauma.\n* Uncompensated internal or oncological disease.\n* Presence of MRI-incompatible metal in the body (e.g., pacemaker).","ALL","60 Years","80 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.",[27,28,29],"Mild Cognitive Impairment (MCI) Amnestic","Lewy Body Disease With Mild Cognitive Impairment","Parkinson's Disease With Mild Cognitive Impairment",[31,32,33,34,35,36,37,38,39],"Temporal Interference Stimulation","Functional Magnetic Resonance Imaging","Sentence Comprehension","Language Processing","Brain Connectivity","Striatum","Fronto-striatal Circuit","Mild Cognitive Impairment","Neurodegenerative Diseases","RECRUITING","2026-02-27",{"date":43,"type":44},"2026-03-04","ACTUAL",{"date":46,"type":21},"2026-03",{"date":48,"type":21},"2028-12",{"name":50,"class":51},"Masaryk University","OTHER"]