[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"paroxysmal-dyskinesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:paroxysmal-dyskinesia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100570023","neural-correlates-of-movement-disorders-associated-with-prrt2-related-paroxysmal-kinesigenic-dyskinesia---an-ancillary-study-of-amedyst-research-100570023",false,"NCT06701851","Neural Correlates of Movement Disorders Associated With PRRT2 Related Paroxysmal Kinesigenic Dyskinesia - an Ancillary Study of AMEDYST Research","Corrélats Neuronaux Des Accès de Mouvements Anormaux Paroxystiques Liées Aux Dyskinésies Paroxystiques kinésigéniques Secondaires à Une Mutation du Gene PRRT2 - Recherche Ancillaire de L'étude AMEDYST \" Dont Vous êtes l'Investigateur Principal","TRIGGER","Inclusion Criteria:\n\nMale or female Individuals with dystonic disease carrying a PRRT2 mutation and demonstrating the ability to control paroxysmal dyskinesia episodes.\n\nAffiliated with a health insurance system or a beneficiary of such a system. Individuals aged 18 to 75 years. Signature of informed consent\n\nExclusion Criteria:\n\nIndividuals under guardianship. Individuals not residing in France. Individuals unable to comply with protocol constraints (compliance with visit schedules and ability to perform required tasks).\n\nIndividuals undergoing an exclusion period for another research study. Contraindications to MRI","ALL","18 Years","75 Years",{"count":5,"type":21},"ESTIMATED","INTERVENTIONAL",[24],"NA","The main objective of this study is to investigate in real-time the neuronal correlates of paroxysmal dyskinesia episodes related to the PRRT2 mutation within this subgroup of patients (who can control paroxysmal dyskinesia episodes), and more specifically, the pathological role of the reciprocal influence between the striatum and the cerebellum in paroxysmal dyskinesia episodes.",[27],"Paroxysmal Dyskinesia",[29,30,31,32,33,34,35],"dyskinesia","voluntary movements","cerebellum","basal ganglia","cortex","fMRI","EEG","RECRUITING","2026-06-03",{"date":39,"type":40},"2026-06-05","ACTUAL",{"date":42,"type":40},"2025-01-21",{"date":44,"type":21},"2029-10",{"name":46,"class":47},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV"]