[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"partial-edentulism\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:partial-edentulism":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,50,79,115,137,159,179],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100627443","intraoral-vs-extraoral-cementation-of-zirconia-bridges-on-ti-bases-microstrain-evaluation-100627443",false,"NCT07448701","Intraoral vs Extraoral Cementation of Zirconia Bridges on Ti-Bases: Microstrain Evaluation","Influence of Cementation Technique on Microstrain in Three-Unit Bridges on Ti-Bases Evaluated by Strain Gauges","Inclusion Criteria:\n\n* Adults (≥18 years old) in good general health.\n* Presence of an edentulous space requiring rehabilitation with a three-unit implant-supported fixed bridge.\n* Presence of two already osseointegrated Essential Cone implants (Klockner) indicated for a three-unit implant-supported restoration in the edentulous area.\n* Ability and willingness to participate and attend study visits and follow-up.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* ASA III or ASA IV.\n* Current or previous treatment with bisphosphonates.\n* Smoking \\>10 cigarettes\u002Fday.\n* Extraction in the study area \\\u003C3 months before implant placement with incomplete healing.\n* Guided bone regeneration in the study area with \\\u003C6 months of healing time.\n* Signs of active periodontal disease (e.g., poor plaque control and\u002For bleeding on probing above acceptable levels).","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","This prospective clinical study compares two cementation techniques for implant-supported zirconia fixed partial dentures on titanium bases (Ti-bases): extraoral cementation performed on the working model and intraoral cementation performed chairside. Thirty clinical cases with two osseointegrated implants requiring a multi-unit zirconia restoration will be recruited at the UIC Dental Clinic. For each case, two restorations with identical design will be produced: one will be cemented extraorally (control) and an identical replica will be cemented intraorally (test). Micro-deformation will be assessed as peri-implant microstrain (µε) using a standardized strain-gauge setup and the same recording protocol for both techniques. The primary analysis compares microstrain between intraoral and extraoral cementation within each case; implant\u002Fprosthetic events will be recorded descriptively.",[26,27],"Biomechanical Phenomena","Partial Edentulism",[29,30,31,32,33,34,35,36],"titanium base","ti-base","zirconia bridge","intraoral cementation","passive fit","screw-retained restoration","strain gauge","CAD\u002FCAM zirconia","NOT_YET_RECRUITING","2026-02-28",{"date":40,"type":41},"2026-03-04","ACTUAL",{"date":43,"type":20},"2026-03",{"date":45,"type":20},"2027-06",{"name":47,"class":48},"Universitat Internacional de Catalunya","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":49},"100617206","in-vivo-evaluation-of-the-accuracy-of-immediate-screw-retained-provisional-crowns-fabricated-using-digital-planning-and-guided-surgery-100617206","NCT07315607","In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery","In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Prefabricated Using Digital Planning and Fully Guided Surgery","Inclusion Criteria:\n\n1. Adults aged 18 years or older.\n2. Partially edentulous patients requiring replacement of a single tooth with an immediately loaded dental implant.\n3. Patients classified as ASA I or ASA II according to the American Society of Anesthesiologists physical status classification.\n4. Patients with clinical conditions allowing immediate implant placement with a minimum primary stability of ≥25 Ncm.\n5. Ability to understand the study procedures and provide written informed consent.\n6. Willingness to comply with the study protocol and attend required clinical visits.\n\nExclusion Criteria:\n\n1. Patients classified as ASA III or ASA IV, or with uncontrolled systemic conditions that may interfere with study participation.\n2. Presence of psychiatric or cognitive disorders that may compromise informed consent or protocol compliance.\n3. Inability to comply with the visit schedule or required evaluations.\n4. Any other condition that, in the investigator's judgment, could compromise patient safety, protocol adherence, or data validity.",true,{"count":59,"type":20},27,[23],"This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery. The study will be conducted in partially edentulous adult patients requiring the replacement of a single tooth with an immediately loaded dental implant.\n\nThe main objective of the study is to assess the accuracy (trueness and precision) of the planned digital implant position and provisional restoration by comparing the virtually planned position with the actual clinical outcome after guided surgery. Emphasis will be placed on linear, angular, and rotational deviations at both the implant and provisional restoration levels.\n\nParticipants will undergo a fully guided implant placement procedure with rotational control, followed by the immediate placement of a prefabricated screw-retained provisional crown designed during the digital planning phase. Postoperative intraoral scans will be obtained to register the final implant and restoration positions.\n\nThe planned and achieved positions will be compared using three-dimensional analysis software to quantify deviations and determine whether the accuracy achieved remains within clinically acceptable limits.",[27,63],"Tooth Loss \u002F Rehabilitation",[65,66,67,68],"Immediate provisionalization","Screw-retained provisional crown","Guided implant surgery","Digital implant planning","RECRUITING","2026-01-08",{"date":72,"type":41},"2026-01-09",{"date":74,"type":20},"2026-01",{"date":76,"type":20},"2027-01",{"name":78,"class":48},"Universidad Complutense de Madrid",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":21,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":4},"100594026","prospective-study-of-bone-augmentation-with-lateral-sinus-lift-and-osseointegration-of-dental-implants-100594026","NCT07014085","Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants","Histomorphometric Evaluation of Bone Augmentation Using Xenograft vs Autologous Bone Graft With Dental Implants. A Comparative Clinical Study.","Inclusion Criteria:\n\n* Partially edentulous jaws in the lateral segment with 2 or more nearby lost teeth in the posterior upper jaw (maxilla), where the vertical height is a minimum of 2mm\n* absence of marginal periodontal disease\n* patients in American Society of Anesthesiologists ASA group 1-2 over 18 years.\n\nExclusion Criteria:\n\n* ASA group 3 and above\n* ongoing infection\n* bruxism or abnormal habit\n* poor oral hygiene\n* medical conditions that may compromise healing (uncontrolled diabetes etc)\n* treatments that interfere with healing in the jaw bone (bisphosphonate, steroid therapy) radiotherapy or chemotherapy within the last 5 years\n* alcohol or substance abuse\n* heavy smoking\n* pregnancy\n* desire not to participate","100 Years",{"count":88,"type":20},20,[23],"By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side. The purpose is to qualify and verify each step of this study to ensure the reliability and validity of the results.",[92,27],"Atrophic Maxilla",[94,95,96,97,98,99,100,101,102,103,104,105],"bone augmentation","dento alveolar surgery","oral surgery","comparative prospective study","clinical study","lateral sinus lift","dental implants","osseointegration","prf","autologus graft","xenograft","atrophic maxilla","2025-06-23",{"date":108,"type":41},"2025-06-24",{"date":110,"type":20},"2025-07-01",{"date":112,"type":20},"2035-12-31",{"name":114,"class":48},"Maria H. Pham",{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":4,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":124,"phases":4,"briefSummary":125,"conditions":126,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":49},"100433722","extra-short-vs-non-extra-short-dental-implants-splinted-on-the-same-prosthesis-100433722","NCT04927819","Extra-short vs. Non-extra-short Dental Implants Splinted on the Same Prosthesis","Prospective Observational Study on Evolution of Extra-short Implants (\u003C6.5 mm) Compared to Non-extra-short Implants (≥ 6.5 mm) Splinted on the Same Prosthesis","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Have planned a fixed multiple prosthesis supported by implants \\\u003C6.5 mm in length and implants ≥ 6.5 mm in length within 15 days before the inclusion of the patient in the study.\n* Planning of supported prostheses from 2 to 4 implants dental\n* Have a previously performed CBCT (Cone Beam Computed Tomography)\n* Availability to be observed during the period of tracing\n* Signature of the informed consent\n\nExclusion Criteria:\n\n* Smokers\\> 10 cigarettes \u002F day\n* Complete prostheses\n* Unitary prostheses",{"count":123,"type":20},102,"OBSERVATIONAL","The main aim of this prospective study is to analyze the survival rate of short-length implants (\\\u003C6.5 mm) in subjects with partial edentulism. Non-short length implant will be used as control arm. Additionally, others clinical parameters (marginal bone loss and prosthetic associated complications) will be measured.",[127],"Partial-edentulism","2025-04-16",{"date":130,"type":41},"2025-04-17",{"date":132,"type":41},"2021-05-11",{"date":134,"type":20},"2025-07-31",{"name":136,"class":48},"Fundación Eduardo Anitua",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":16,"minAge":144,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":21,"phases":147,"briefSummary":148,"conditions":149,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":4},"100564385","surgical-guided-fabricated-from-two-different-printing-materials-100564385","NCT06628492","Surgical Guided Fabricated From Two Different Printing Materials","Comparative Assessment for the Positional Accuracy of Dental Implants Inserted by Computerized Surgical Guides Fabricated From Different Printing Materials","Inclusion Criteria:\n\n1. Patients with skeletal Angle´s class I maxilla-mandibular relationship,\n2. adequate inter-arch distance, have Kennedy class 3 or 4 partially edentulous mandible of more than 2 teeth missed and will be applied for the treatment of tooth loss and requiring fixed prosthodontic rehabilitation\n3. normal Physical and psychological status to tolerate conventional implant procedures,\n4. Their residual ridge had sufficient bone volume for implant installation and was covered by firm mucoperiosteum.\n\nExclusion Criteria:\n\n1. Smokers.\n2. Patients undergoing chemotherapy or radiotherapy and immunocompromised patients.\n3. Patients with, systemic disease that might complicate post-operative healing or contribute to bone resorption, e.g uncontrolled diabetes, psychological disorders, or alcohol, tobacco, or drug abuse\n4. parafunctional habits, poor oral hygiene, limited mouth opening, severe alveolar bone deficiencies,","21 Years",{"count":146,"type":20},12,[23],"implant will be inserted in patients with kennedy class 3 or 4 partially edentulous mandible .the implants will be inserted using teeth supported surgical guide fabricated from two different materials",[127],"2024-10-03",{"date":152,"type":41},"2024-10-08",{"date":154,"type":20},"2024-10",{"date":156,"type":20},"2024-11",{"name":158,"class":48},"Suez Canal University",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":57,"sex":16,"minAge":144,"maxAge":4,"enrollmentInfo":165,"targetDuration":4,"studyType":21,"phases":167,"briefSummary":168,"conditions":169,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":49},"100537101","a-smart-digital-workflow-towards-high-precision-and-through-put-production-for-removable-partial-dentures-100537101","NCT06273449","A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures","Inclusion Criteria:\n\n* above the age of 21 years' old\n* medically fit\n* with prior denture experience\n* either maxillary or mandible partial dentate\n* partial edentulism with stable occlusion\n\nExclusion Criteria:\n\n* History of maladaptation to denture use\n* With maxillofacial or mandible bone defect(s)\n* Known allergic reaction to cobalt chromium metal",{"count":166,"type":20},141,[23],"Tooth loss is a major chronic problem in dentistry and edentulous elderly endures poorer quality of life worldwide. Removable partial dentures (RPDs) are the most widely accepted and cost-effective treatment for patients to restore oral functions. RPDs contain three components including the metal framework, denture base and acrylic teeth. Conventionally, RPD fabrication involves tedious clinical and dental laboratory procedures and is time consuming, labour-intensive, and often imprecise, therefore incapable of meeting the growing demands of RPD by an ageing population. The challenges to achieve a high quality and high-throughput RPD service lie in three aspects: 1) accuracy in capturing oral profile; 2) immediate oral information analysis and device design, and 3) automation in production.",[127],"2024-08-07",{"date":172,"type":41},"2024-08-09",{"date":174,"type":41},"2022-12-29",{"date":176,"type":20},"2025-12-31",{"name":178,"class":48},"National Dental Centre, Singapore",{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":186,"targetDuration":4,"studyType":21,"phases":188,"briefSummary":189,"conditions":190,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":197,"locationsCount":49},"100375301","clinical-performance-of-long-span-fixed-partial-dentures-100375301","NCT04166695","Clinical Performance of Long-span Fixed Partial Dentures","Clinical Performance of Long-span All-ceramic or Metal-ceramic Fixed Partial Dentures on Implants and\u002For Natural Teeth","Inclusion Criteria:\n\n* The patient is at least 18 years old.\n* The patient has unrestricted legal capacity.\n* The patient has two posterior teeth (premolars and \u002F or molars) that are to be replaced next to each other.\n* The patient is reliable and willing to take part in follow-up examinations regularly and over the entire study period (three years).\n* The information about the study has been understood by the patient and the signed declaration of consent has been received.\n\nExclusion Criteria:\n\n* Pregnancy and lactation\n* Local and \u002F or systemic acute and \u002F or chronic (also in the past) general medical diseases and conditions that contradict participation in the study and \u002F or expose the patient to a higher risk in the case of participation in the study.\n* Severe bruxism diagnosed by a portable electrocardiomyography device (BruxOff) (\\> 4 bruxism episodes \u002F night)\n* Reduced clinical crown height (\\\u003C 5 mm before tooth preparation)\n* Limited periodontal health:\n\n  * probing depths \\> 4 mm or = 4 mm and bleeding on probing,\n  * Furcation involvement \\> I (first band of the periodontometer after Naber disappears completely)\n  * Degree of loosening of the abutment teeth \\> Grade I (\\> 1 mm horizontal mobility)\n* Untreated endodontic problems of abutment teeth\n* Lack of antagonistic support from fixed dentures or natural teeth\n* Known allergies or intolerances to the materials used in the study\n* Lack of oral hygiene\n* Lack of compliance\n* Planned change of residence\n* Rejection of randomisation",{"count":187,"type":20},40,[23],"Tooth-coloured fixed restorations are becoming increasingly popular with patients and dentists. If high-strength all-ceramics such as zirconia are used as the restoration material, a maximum of two adjacent missing teeth can be replaced with the aid of fixed partial dentures (FPDs). For the replacement of a missing anterior or posterior tooth by FPDs, a very good clinical performance similar to that of metal-based, ceramic-veneered restorations can be expected. However, evidence-based statements on the clinical performance of long-span all-ceramic FPDs are difficult because there are only very few studies on this topic, which are also inhomogeneous with regard to the study conditions. Randomized studies to compare monolithic (consisting only of the high-strength framework material) or partially veneered (weaker veneering ceramics in esthetically relevant tooth areas) all-ceramic and classic (completely veneered) metal-ceramic FPDs are lacking. The aim of the current explorative, prospective, randomized, two-arm clinical interventional study is therefore to compare the clinical performance of long-span FPDs (≥ 4 Pontics) made of monolithic \u002F facially veneered zirconium dioxide with a gold standard (completely veneered cobalt chromium (CoCr)-based FPDs). Forty patients will be recruited. Once all inclusion criteria have been established, including the signed informed consent of the patients informed of the content, effort, advantages and disadvantages of the study, patients are assigned to the two study groups by stratified block randomization (main strata: tooth-supported \u002F (tooth-)implant-supported). After placement of the restorations, follow-up examinations are performed after 1 week (baseline) and after half a year, one year, two years and three years. In addition to the main target criterion (veneering defects), further complications (related to FPDs or supporting tissues \u002F structures) and parameters of oral health are recorded. Depending on the distribution and structure of the data, parametric and non-parametric statistics are used. Group differences with respect to the main target criterion ceramic defects are to be investigated by log-rank and chi-square tests. The significance level is set at α \\\u003C 0.05. Since this is an explorative study, all p-values are descriptive.",[27],"2023-05-08",{"date":193,"type":41},"2023-05-09",{"date":195,"type":41},"2020-01-09",{"date":76,"type":20},{"name":198,"class":48},"University Hospital Heidelberg"]