[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"patellar-dislocation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:patellar-dislocation":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,51,80,108,133],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100583981","jupiter-40---risk-factors-for-failure-of-isolated-medial-patellofemoral-ligament-reconstruction-100583981",false,"NCT06883396","JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction","Inclusion Criteria:\n\n* 10-35 years old\n* Recurrent patellar instability with at least one episode defined as either (1) a dislocated patella requiring reduction in the emergency department or (2) a convincing history for dislocation, associated with full giving way, and the following physical findings: (a) hemarthrosis or effusion, (b) tenderness along the medial retinaculum, and (c) apprehension when laterally directed force was applied to the patella or (3) MRI-documented dislocation with associated bone bruises\n\nExclusion Criteria:\n\n* Previous ipsilateral knee surgery\n* Obligatory\u002Ffixed\u002Fhabitual patella dislocation or subluxation\n* Unloadable inferior or lateral chondral damage on the patella that would require a tibial tubercle transfer for unloading purposes\n* Pathologic tibiofemoral instability","ALL","10 Years","35 Years",{"count":19,"type":20},850,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability. The main questions it aims to answer are:\n\n* What are the risk factors for recurrent patellar instability after MPFL reconstruction?\n* What functional outcomes do patients report after MPFL reconstruction?\n\nParticipants undergoing MPFL reconstruction will answer survey questions about their knee and activity level 1 year and 2 years after surgery.",[24,25,26,27,28,29],"Patellar Dislocation, Recurrent","Patellar Dislocation","Patellar Instability","Patellofemoral Dislocation","Patellofemoral Joint Dislocation","Patellofemoral Disorder",[31,32,26,33,34,35,36,37],"Patella","Patella Dislocation","Recurrent Patellar Instability","MPFL","Medial Patellofemoral Ligament","Medial Patellofemoral Ligament Reconstruction","Patellofemoral Instability","RECRUITING","2026-02-11",{"date":41,"type":42},"2026-02-13","ACTUAL",{"date":44,"type":42},"2023-01-01",{"date":46,"type":20},"2027-12",{"name":48,"class":49},"Hospital for Special Surgery, New York","OTHER",16,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100587308","mpfl-reconstruction-versus-rehabilitation-100587308","NCT06926699","MPFL Reconstruction Versus Rehabilitation","RehAbilitatioN Versus Early Medial PaTellofemoral LIGament Reconstruction in Patients With Acute First-Time PateLlar DIslocation: A Pilot RanDomized ControllEd Trial","ANTI-GLIDE","Inclusion Criteria:\n\n1. Males and female patients under the age of 25 inclusive but greater than 10 years of age inclusive\n2. Patients with first-time traumatic lateral patellar dislocation presenting within 6 months from time of injury\n3. Lateral patellar dislocation confirmed by radiography, MRI demonstrating sequela of lateral patellar dislocation after injury to the knee, demonstration of patellar apprehension, J-sign or patellar glide grade 3 or greater on physical exam following injury to the knee\n4. Patients who have the ability to speak, understand, and read English\n5. Provision of informed consent or parental consent\n\nExclusion Criteria:\n\n1. Previous dislocation episodes or instability of the affected patella\n2. Previous surgeries involving the affected knee\n3. History or clinical exam findings of generalized ligamentous laxity (defined as Beighton score of 4 or more points)\n4. TT-TG distance \\>20mm as determined by MRI\n5. Evidence of severe trochlear dysplasia on MRI as determined by Dejour classification type D dysplasia\n6. Loose bodies or osteochondral fractures as confirmed on MRI\n7. A neurovascular injury of the affected leg\n8. Patients who will likely have problems, in the judgment of the investigator, with maintaining follow-up\n9. Any other reason(s) the investigator feels is relevant for excluding the patient\n10. Patients requiring concomitant arthrotomy for osteochondral fracture fixation (however microfracture and arthroscopic loose body removal for loose bodies found on arthroscopic assessment are not exclusion criteria)","25 Years",{"count":61,"type":20},30,"INTERVENTIONAL",[64],"NA","This study involves patients between the ages of 16 and 25 and have been diagnosed with a first-time traumatic patellar dislocation within the past 3 months. McMaster University and the investigators are receiving compensation from the Arthroscopy Association of North America to cover the costs of conducting the study.\n\nDislocations of the kneecap or patella is often treated without surgery, however up to 50% of patients will unfortunately experience recurrent instability of the patella. These episodes can cause damage to the bones and cartilage in the knee, which can result in long-term knee pain or weakness. Therefore, there is increasing interest to consider treating the knee with surgery right away in this population.\n\nThe purpose of this study is to determine the effect of medial patellofemoral ligament (MPFL) reconstruction compared to rest and physical rehabilitation on the rate of repeat patella dislocation, pain, and knee function for patients with their first patellar dislocation. The investigators will follow patients for at least one year after assigned treatment is started. Outcomes will be measured using surveys and checking medical records over the course of the study. The pilot will test this research study on a smaller scale before conducting a larger study. Patients will not be asked to attend additional visits outside of their typical follow-up schedule with their doctor.\n\nThere will be 30 patients recruited in total for this pilot study. Not all patients diagnosed with a patellar dislocation will be eligible to participate. Participation will be required at 6 regularly scheduled appointments that patients would need to attend to see the surgeon (even if they were not in the trial), including the screening visit, surgery date (if randomized to that treatment), 2-week, 6-week, 3-month, 6-month, and 12-month follow-up visits. Patients will be asked how they feel via various questionnaires and should take no longer than 15-20 minutes to complete the research forms at each visit.\n\nIf patients agree to participate in this study, treatment will be determined by a process called randomization. Randomization means that the treatment the patient receives will be decided by chance like flipping a coin. Patients will have a 1-in-2 chance of receiving one of the following treatments:",[67,25],"Patellar (or Kneecap) Instability and Mal-alignment",[34,36,69],"Patellar dislocation","NOT_YET_RECRUITING","2025-09-22",{"date":73,"type":42},"2025-09-25",{"date":75,"type":20},"2026-01-01",{"date":77,"type":20},"2027-12-31",{"name":79,"class":49},"McMaster University",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":15,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":62,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":107},"100405041","blood-flow-restriction-training-after-patellar-instability-100405041","NCT04554212","Blood Flow Restriction Training After Patellar INStability","Blood Flow Restriction Training After Patellar INStability (BRAINS Trial)","BRAINS","Inclusion Criteria:\n\n* Diagnosis of traumatic patellar instability (either primary or recurrent) determined by an American Board of Family Medicine certified physician with a Certificate of Added Qualifications in Sports Medicine or licensed Physical Therapist utilizing clinical examination, radiographic imaging, and patients' reports of instability\n* Age 14 to 40 years\n* Skeletally mature with closed growth plates visualized by radiograph\n* A score of 80 or more on the Sports Activity Scale, which corresponds to participating in \"running, twisting, turning (tennis, racquetball, handball, ice hockey, field hockey, skiing, wrestling)\" at least 1-3 times per week\n* Desire to resume pre-injury activity level\n\nExclusion Criteria:\n\n* Concomitant osteochondral lesion requiring surgical fixation\n* Radiographic evidence of osteoarthritis (\\\u003C Kellgren-Lawrence Grade 2)\n* Previous ipsilateral or contralateral knee surgery\n* Most recent instability event more than 3 months before enrollment\n* History of any inflammatory disorder\n* BMI \\> 35 kg\u002Fm2\n* Diabetes or uncontrolled hypertension\n* Varicose veins or a history of personal or immediate family history (parental or sibling) of deep vein thrombosis\n* Pre-existing conditions or previous surgeries that effect the ability to walk\n* Planned trips or vacations that will result in the inability to attend 4 consecutive physical therapy sessions","14 Years","40 Years",{"count":91,"type":20},78,[64],"This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery for those with patellar instability.",[25,95,96,97],"Knee Injuries","Leg Injury","Wounds and Injuries","2025-07-02",{"date":100,"type":42},"2025-07-03",{"date":102,"type":42},"2020-09-09",{"date":104,"type":20},"2026-06-30",{"name":106,"class":49},"Caitlin Conley",4,{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":89,"enrollmentInfo":115,"targetDuration":4,"studyType":62,"phases":117,"briefSummary":118,"conditions":119,"keywords":120,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":132},"100522704","non-operative-treatment-in-first-time-patellar-dislocation-100522704","NCT06086080","Non-operative Treatment in First-time Patellar Dislocation","Non-operative Treatment in First-time Patellar Dislocation: a Randomized Controlled Trial","Inclusion Criteria:\n\n\\- Patients with first episode of acute lateral patellar dislocation during the last 7 days.\n\nExclusion Criteria:\n\n\\* Patients with acute bilateral patellar dislocation.\n\n* Patients with open patellar dislocation.\n* Patients with previous knee surgery in the same knee.",{"count":116,"type":20},50,[64],"Study to evaluate the conservative treatment of patients after their first episode of primary lateral patellar dislocation. Randomized controlled trial with 2 groups: standard treatment (2-weeks with brace) followed by physical therapy, compared with knee taping and physical therapy. 1-year follow-up. Measurements include physical exam, radiographs and MRI. Outcomes: recurrence, lateral patellar tilt, functional scores, apprehension, pain.\n\nHypothesis: less recurrence in the knee taping group, as well as better functional scores.",[25],[69,121,122],"Brace","Knee taping","2025-03-31",{"date":125,"type":42},"2025-04-03",{"date":127,"type":42},"2023-10-02",{"date":129,"type":20},"2027-12-01",{"name":131,"class":49},"Fundacion Clinica Valle del Lili",1,{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":141,"sex":15,"minAge":142,"maxAge":143,"enrollmentInfo":144,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":146,"conditions":147,"keywords":151,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":132},"100409134","the-faroese-knee-cohort-etiology-and-long-term-implications-of-trochlear-dysplasia-and-patellar-dislocations-100409134","NCT04607538","The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.","The Faroese Knee Cohort: An Investigation of Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations","FKC","Inclusion Criteria:\n\n* Age between 15-20 years at the start of patient enrolment.\n* The feeling of patellar instability, or patellar dislocation\u002Fnear-dislocation.\n* The person has to be from the Faroe Islands.\n* All persons under the age of 18 must get written consent by their parents\n\nExclusion Criteria:\n\n* Terminal illness\n* Mental disabilities and illness, meaning that the patient cannot independently answer the PROM´s and cooperate to the clinical investigation.",true,"15 Years","20 Years",{"count":145,"type":20},100,"The investigators intend to establish a national cohort including all persons in the ages from 15-20 years old with patellar instability (PI) or a prior knee injury (ACL-ruptur or meniscus damage) . The cohort will be nicknamed \"The Faroese Knee Cohort\".\n\nThe overall aim is to investigate two groups.\n\n1. The patella instability group, in which we intend to investigate the following.\n\n   * Prevalence of patellar dislocation and trochlear dysplasia in the Faroe Islands.\n   * Risk factors for patellar dislocations-\n   * Heredity of trochlear dysplasia.\n   * If there is a specific gene responsible for the development of trochlear dysplasia.\n   * The development of retropatellar artrhosis, its onset and its impact on quality of life and function,\n2. Knee injury group (ACL-ruptur or meniscus injury)\n\n   * The prevalence of ACL-rupture and\u002For meniscus injury in this specific group in the Faroe Islands.\n   * The impact on quality of life and function.",[25,148,149,150],"ACL Injury","Meniscus Lesion","Trochlear Dysplasia",[152,69,153,154,155],"Patellar instability","ACL-rupture","Meniscus lesion","Meniscus injury","2023-02-15",{"date":158,"type":42},"2023-02-17",{"date":160,"type":42},"2022-03-01",{"date":162,"type":20},"2051-12-01",{"name":164,"class":49},"Hvidovre University Hospital"]