[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"patellofemoral-pain-pfp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:patellofemoral-pain-pfp":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,54,80,103,123,147],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100644562","effects-of-kinesio-taping-versus-mcconnell-taping-on-clinical-outcomes-in-patients-with-patellofemoral-pain-syndrome-100644562",false,"NCT07671482","Effects of Kinesio Taping Versus McConnell Taping on Clinical Outcomes in Patients With Patellofemoral Pain Syndrome.","Effects of Kinesio Taping Versus McConnell Taping on Clinical Outcomes in Patients With Patellofemoral Pain Syndrome. A Randomized Clinical Trial.","PFPS","Inclusion Criteria:\n\n* Anterior or retropatellar pain for a minimum of 3 months during functional activities.\n* 18-50 years of age.\n* Minimum pain of 3\u002F10 on the VAS score.\n* No LL physical therapy in the past 3 months.\n\nExclusion Criteria:\n\n* Meniscal or ligamentous injury\n* Neurological or systemic conditions affecting proprioception, coordination and balance.\n* Spinal referred pain or rheumatoid arthritis.\n* Hip and ankle disorders.","ALL","18 Years","50 Years",{"count":21,"type":22},80,"ESTIMATED","INTERVENTIONAL",[25],"NA","The primary goal of this randomized clinical trial (RCT) is to evaluate whether Kinesio Taping versus McConnell Taping, when integrated into a standardized hip-knee strengthening and neuromuscular control program, produces significant effects in individuals aged 18-50 with patellofemoral pain syndrome (PFPS).\n\nThe main question it aims to answer is: Does Kinesio Taping compared with McConnell Taping when both combined with a standardized hip-knee exercise program, produce different effects on quadriceps neuromuscular activation (VMO-VL sEMG), pain, functional knee pain, and dynamic knee valgus over a 6 week period intervention?\n\nParticipants will be divided into three groups for comparison: the control group will receive a structured hip-knee physical therapy exercise program without any taping intervention, Kinesio Taping group with a standardized exercise program, and a McConnell Taping group with a standardized exercise program.",[28,29,15,30,31,32,33],"Patello Femoral Pain Syndrome","Anterior Knee Pain Syndrome","Patellofemoral Pain Syndrome","Patellofemoral Disorder","Patellofemoral Pain, PFP","Patellofemoral Pain (PFPS)",[35,36,37,38,39,30,40],"Electromyography","EMG","Kinesio Taping","McConnell Taping","Exercise Therapy","Single-Leg Squat","RECRUITING","2026-06-25",{"date":44,"type":45},"2026-06-26","ACTUAL",{"date":47,"type":22},"2026-06",{"date":49,"type":22},"2026-10",{"name":51,"class":52},"Cairo University","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":23,"phases":64,"briefSummary":65,"conditions":66,"keywords":67,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100635830","telerehabilitation-for-patellofemoral-pain-100635830","NCT07557784","Telerehabilitation for Patellofemoral Pain","Telerehabilitation Versus Face-to-Face Supervised Rehabilitation for Patellofemoral Pain: A Randomized Non-Inferiority Trial","* Inclusion Criteria\n\n  * Aged 18 to 45 years\n  * Clinical diagnosis of patellofemoral pain\n  * History of anterior or retropatellar knee pain for at least 3 months\n  * Pain provoked by at least two of the following activities: stair ambulation, squatting, running, jumping, or prolonged sitting\n  * Baseline knee pain intensity of at least 3\u002F10 on the Numerical Rating Pain Scale\n  * Willing and able to participate in the rehabilitation program and follow-up assessments\n  * Able to provide written informed consent\n* Exclusion Criteria\n\n  * Previous knee surgery\n  * History of patellar dislocation or instability\n  * Evidence of ligament injury, meniscal injury requiring separate management, moderate to severe knee osteoarthritis, or other major structural knee pathology\n  * Concurrent hip, ankle, lumbar spine, or other musculoskeletal disorders substantially affecting lower limb function\n  * Neurological disorders affecting movement or balance\n  * Severe cardiopulmonary or systemic disease contraindicating exercise\n  * Received structured lower limb rehabilitation within the previous 3 months\n  * Pregnancy\n  * Any other condition judged by the investigators to make participation unsuitable","45 Years",{"count":63,"type":22},106,[25],"Patellofemoral pain (PFP) is a common musculoskeletal condition characterized by pain around or behind the patella during activities such as stair ambulation, squatting, running, jumping, and prolonged sitting. Exercise therapy combined with patient education is considered first-line treatment, and supervised rehabilitation is commonly used to improve adherence and clinical outcomes.\n\nTelerehabilitation may increase accessibility and reduce time and travel burden, but high-quality evidence remains limited regarding whether telerehabilitation provides outcomes that are not inferior to conventional face-to-face supervised rehabilitation in individuals with PFP.\n\nThis study is a randomized, assessor-blinded, non-inferiority trial designed to compare telerehabilitation with face-to-face supervised rehabilitation in individuals with patellofemoral pain. The trial will evaluate whether telerehabilitation is not inferior to face-to-face supervised rehabilitation in improving pain and knee-related function, while also examining psychological outcomes, self-satisfaction, and adherence.",[32],[68,69],"Telerehabilitation","Patellofemoral Pain","NOT_YET_RECRUITING","2026-04-25",{"date":73,"type":45},"2026-04-29",{"date":75,"type":22},"2026-05-20",{"date":77,"type":22},"2027-03-20",{"name":79,"class":52},"Beijing Sport University",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":87,"minAge":18,"maxAge":61,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":93,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":53},"100635831","gait-retraining-for-runners-with-patellofemoral-pain-100635831","NCT07557797","Gait Retraining for Runners With Patellofemoral Pain","Gait Retraining Intervention for Female Runners With Patellofemoral Pain: Randomized Controlled Trial","Inclusion Criteria:\n\n* Female, Age 18-45 years\n* Unilateral\u002Fbilateral anterior knee pain \\> 4 weeks\n* VAS pain ≥ 3\u002F10 during running and ≥ 2 of the following: jumping, squatting, kneeling, stairs, prolonged sitting, or resisted knee extension\n* Running ≥ 15 km per week\n* Natural rearfoot striker\n\nExclusion Criteria:\n\n* Acute trauma, history of patellar dislocation, meniscal\u002Fchondral lesions\n* Prior knee surgery or injection in past 12 months\n* Rheumatologic, neurologic, or degenerative disease\n* Pregnancy","FEMALE",{"count":89,"type":22},44,[25],"Patellofemoral pain (PFP) is a common overuse injury in runners. Increased patellofemoral joint stress (PFJS) is an important biomechanical factor associated with PFP. Gait retraining, especially cadence modification, may reduce PFJS and improve symptoms, but evidence from randomized controlled trials remains limited. This study investigated whether wearable device-assisted gait retraining was more effective than education alone in reducing pain, improving function, and altering running biomechanics in female runners with PFP.",[32],[94,95,96],"Patellofemoral pain","gait retraining","runner",{"date":73,"type":45},{"date":99,"type":22},"2026-05-15",{"date":101,"type":22},"2026-12-15",{"name":79,"class":52},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":61,"enrollmentInfo":109,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":53},"100622533","effects-of-attentional-focus-strategies-during-isokinetic-quadriceps-training-on-strength-and-functional-performance-in-individuals-with-patellofemoral-pain-syndrome-100622533","NCT07384858","Effects of Attentional Focus Strategies During Isokinetic Quadriceps Training on Strength and Functional Performance in Individuals With Patellofemoral Pain Syndrome.","Inclusion Criteria:\n\n* Aged between 18 and 45 years.\n* Diagnosed with patellofemoral pain syndrome (PFPS).\n* Anterior or retropatellar knee pain persisting for at least four weeks with a VAS score \\> 3.\n* Pain exacerbated by at least two functional activities (e.g., squatting, stair climbing, prolonged sitting).\n* Willing to regularly participate in the 6-week program throughout the study period.\n\nExclusion Criteria:\n\n* History of patellar subluxation or dislocation.\n* Anterior or posterior cruciate ligament insufficiency.\n* Lower extremity fractures.\n* Neurological or systemic musculoskeletal disorders.\n* Rheumatoid arthritis or other inflammatory joint diseases.\n* History of knee surgery, meniscal injury, or any other underlying musculoskeletal condition that would prevent the participant from performing the exercises.\n* Pregnancy or postpartum period.\n* Participation in a similar exercise program within the last 3 months.\n* Radiographic evidence of osteoarthritis classified as Kellgren-Lawrence grade 2 or higher.",{"count":110,"type":22},36,[25],"Patellofemoral pain syndrome (PFPS) is a multifactorial musculoskeletal condition that is common particularly among young and physically active individuals, negatively affecting activities of daily living and physical performance. Although exercise therapy is considered the gold standard in the management of PFPS, there is limited evidence regarding the effectiveness of motor learning strategies applied during exercise. This study aims to shed light on how motor learning approaches can be optimized in clinical rehabilitation by comparing the effects of internal and external focus strategies used during exercise on muscle activation, functional performance, and pain.\n\nThis research will make a methodological contribution to the literature through the objective evaluation of muscle mechanical properties using isokinetic assessment and the MyotonPRO device. The findings are expected to clarify the effects of attentional focus strategies on therapeutic outcomes in PFPS rehabilitation and have the potential to provide an evidence-based guide for physiotherapy practice. In this way, the study may contribute to the development of new approaches aimed at improving both clinical effectiveness and patient adherence.",[32],"2026-02-09",{"date":116,"type":45},"2026-02-11",{"date":118,"type":45},"2026-02-02",{"date":120,"type":22},"2026-09-02",{"name":122,"class":52},"Istanbul University - Cerrahpasa",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":23,"phases":133,"briefSummary":134,"conditions":135,"keywords":136,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":53},"100622316","whole-body-vibration-in-patients-with-patellofemoral-pain-syndrome-100622316","NCT07382037","Whole-Body Vibration in Patients With Patellofemoral Pain Syndrome","Efficacy of Whole-Body Vibration in Patients With Patellofemoral Pain Syndrome: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial","Inclusion Criteria:\n\n* Aged between 18 and 40 years,\n* Diagnosed with unilateral Patellofemoral Pain Syndrome (PFPS),\n* Reporting anterior knee pain or pain behind the patella in at least two of the following activities:\n\nascending stairs, jumping, running, squatting, kneeling, prolonged sitting,\n\n\\- Positive results in at least two of the following clinical tests: Eccentric step-down test, Patellar border tenderness test, Patellar grind (Clarke's) or apprehension test,\n\n* Ability to understand the procedures, potential benefits, and possible adverse effects,\n* Willingness to participate in the treatment program.\n\nExclusion Criteria:\n\n* Severe injury or pathological changes in knee structures (e.g., ligaments, menisci, patellar tendons, iliotibial bands, joint capsules, or plicae),\n* History of significant trauma or surgery involving the knee or lower extremity,\n* History of patellar dislocation or subluxation,\n* Diagnosis of Osgood-Schlatter disease or Sinding-Larsen-Johansson syndrome,\n* Joint effusion in the knee, or presence of redness, swelling, or increased warmth on physical examination,\n* Serious systemic conditions, including cardiovascular diseases, tumors, gallstones or kidney stones, severe disc or spinal lesions, pacemaker implantation, epilepsy, recent fractures or surgeries, or acute arthritis,\n* Pregnancy.","40 Years",{"count":132,"type":22},40,[25],"Patellofemoral Pain Syndrome (PFPS), or anterior knee pain, is one of the most common disorders affecting the lower extremities.\n\nCurrently, there is no established \"gold standard\" treatment for PFPS. However, various interventions-including strengthening of the hip and knee muscles (e.g., hip abductors, external rotators, and knee extensors), taping, bracing, foot orthoses, manual therapy, acupuncture, blood flow restriction training, and conventional physical agents (e.g., ultrasound, cryotherapy, neuromuscular electrical stimulation, laser therapy, electromyographic biofeedback, etc.)-have been reported to provide meaningful clinical benefits. Strengthening of the hip and knee muscles alone has been shown to improve both pain and function in the short, medium, and long term. In recent high-quality studies, hip and knee muscle strengthening has been recognized as an effective \"classical\" treatment approach for PFPS. Regarding the mechanism of pain relief, previous research suggests that strengthening these muscles may alleviate pain by stabilizing patellar motion and\u002For reducing pressure on the patellofemoral joint.\n\nSimilar to traditional resistance training, whole-body vibration (WBV) training is an alternative method for muscle strengthening. WBV platforms can generate vertical vibrations that stimulate tonic vibration reflexes through muscle spindles, thereby activating homonymous alpha motor neurons and inducing reflex muscle contractions. As a result, increased motor unit recruitment enhances the excitability of muscle spindles, leading to improved muscle strength. Additionally, WBV training can improve muscle balance, strength, and function. Therefore, combining WBV with hip and knee strengthening exercises may represent a more effective treatment strategy for PFPS. The aim of this study is to evaluate whether the combination of WBV and hip-knee muscle strengthening is more effective in reducing pain and improving function than hip-knee strengthening alone.",[32],[137,138],"whole body vibration","knee","2026-01-25",{"date":118,"type":45},{"date":142,"type":22},"2026-01-15",{"date":144,"type":22},"2026-08-01",{"name":146,"class":52},"Pamukkale University",{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":154,"enrollmentInfo":155,"targetDuration":4,"studyType":23,"phases":157,"briefSummary":158,"conditions":159,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":164,"leadSponsor":166,"locationsCount":4},"100589772","a-study-on-the-effectiveness-of-ankle-dorsiflexion-range-of-motion-training-in-patients-with-patellofemoral-joint-pain-100589772","NCT06958757","A Study on the Effectiveness of Ankle Dorsiflexion Range of Motion Training in Patients With Patellofemoral Joint Pain.","This RCT Included 64 Participants (18-30y) With PFP, Ankle Dorsiflexion ROM \u003C10°, and BMI 18.5-28 kg\u002Fm². Exclusions: Ankle Fractures, Achilles Rupture, Rheumatoid Arthritis, Gout, Systemic Diseases, or Prior Knee\u002FAnkle Surgeries. Randomized to Two Groups (n=32\u002FGroup): Experimental (Standard Exercise + Ankle Dorsiflexion Training) vs Control (Standard Exercise Only) at Matched Intensity\u002FFrequency for 8 Weeks. Outcomes: VAS Pain, Kujala Scale, Ankle Dorsiflexion ROM. Certified Physiotherapists Supervise Sessions. Data Analyzed With SPSS 26.0. The Protocol Complies With the Helsinki Declaration.","Inclusion Criteria:\n\n* Aged 18-30 years\n* Diagnosed with patellofemoral pain (PFP) per clinical guidelines (anterior knee pain aggravated by ≥2 activities: running, squatting, stair climbing)\n* Ankle dorsiflexion range of motion (ROM) \\\u003C10° (measured via goniometer in weight-bearing)\n* BMI 18.5-28 kg\u002Fm²\n* Engage in regular physical activity (≥3 sessions\u002Fweek)\n\nExclusion Criteria:\n\n* Ankle fractures\n* Achilles tendon rupture\n* Rheumatoid arthritis\n* Gout, or systemic diseases\n* Prior knee\u002Fankle surgeries\n* Concurrent lower limb injuries (e.g., ligament tears, meniscal pathology)\n* Neurological disorders affecting mobility\n* Participation in other lower limb rehabilitation programs within 3 months","30 Years",{"count":156,"type":22},64,[25],"Patellofemoral Pain (PFP) is a common knee condition causing pain around the kneecap during activities like running or squatting. Limited ankle flexibility (\"dorsiflexion\" - how far participants can lift their toes toward the shin) may worsen PFP by altering leg movements. This study investigates whether adding ankle flexibility exercises to standard knee-strengthening programs improves outcomes for young adults with PFP. Active adults aged 18-30 with PFP and limited ankle flexibility (measured with a simple tool) are eligible, excluding those with prior knee\u002Fankle surgeries, fractures, or conditions like arthritis. Sixty-four participants will be randomly assigned to either an Exercise + Ankle Training group (standard knee exercises plus targeted ankle training) or an Exercise-Only group for 8 weeks under physiotherapist guidance. Outcomes include improvements in knee pain scores (Kujala Scale), ankle flexibility changes, and muscle coordination measured with non-invasive sensors. If effective, ankle flexibility training could provide a low-cost addition to current treatments, helping patients resume activities with less pain. The study follows international ethical guidelines and has received preliminary ethics approval (No. TJUS-2025-054).",[32],"2025-04-25",{"date":162,"type":45},"2025-05-06",{"date":162,"type":22},{"date":165,"type":22},"2025-09-10",{"name":167,"class":52},"Tianjin University of Sport"]