[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"patellofemoral-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:patellofemoral-pain":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,78,102,127],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100567209","evaluating-the-effectiveness-of-clinical-practice-guideline-adherence-for-patellofemoral-pain-100567209",false,"NCT06665204","Evaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain","Evaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain (knEE-CAPP)","knEE-CAPP","Inclusion Criteria:\n\n* Active-duty Service member\n* Aged ≥18 years\n* Presence of unilateral or bilateral PFP based on the core criterion of peripatellar and\u002For retropatellar pain with reproduction of PFP by at least one activity that loads the patellofemoral joint during weight bearing on a flexed knee, such as prolonged sitting, kneeling, squatting, hopping, running, stair climbing, patellar palpation\n* Available to participate in physical therapy treatment within 6 weeks of initial enrollment\n\nExclusion Criteria:\n\n* Presence of tibiofemoral OA based on imaging evidence in the electronic health records in the past year or self-report\n* History of patellar or intra-articular knee trauma (e.g., dislocation\u002Ffracture) or surgery\n* History of neurodegenerative conditions that may affect movement patterns (e.g., Multiple Sclerosis)\n* Meniscal or ligamentous pathologies within the past year based on imaging evidence of acute injury in the electronic health record or self-report\n* Quadriceps or patellar tendon injuries within the past year based on imaging evidence of acute injury in the electronic health record or self-report\n* Known pregnancy (pregnant females may be eligible for participation after end of pregnancy and medical clearance by a qualified and licensed healthcare provider)\n* Receipt of physical therapy care for PFP within the three months prior to enrollment\n* Known to be pending medical evaluation board, discharge from the military, scheduled deployment, or litigation for an injury at time of enrollment.","ALL","18 Years",{"count":20,"type":21},440,"ESTIMATED","INTERVENTIONAL",[24],"NA","The overall goal of this multisite, randomized clinical trial is to evaluate the short- and long-term effectiveness of a Clinical Practice Guideline (CPG)-adherent physical therapy approach to patellofemoral pain (PFP) management among military Service members. The main questions it aims to answer are:\n\n1. Can a CPG-adherent care approach to PFP management improve short- and long-term knee function, pain, and confidence with completing duty-related activities?\n2. Can a CPG-adherent care approach to PFP management reduce utilization of healthcare resources and analgesic medication prescription at 12-month follow-up?\n3. Are there patient- and care-specific factors that predict or mediate clinical benefit from physical therapy care for PFP?\n\nResearchers will compare the CPG-adherent physical therapy intervention to usual physical therapy care in the Military Health System.\n\nParticipants will: 1) be randomized to receive CPG-adherent care or usual care for PFP management; 2) attend physical therapy corresponding to their group assignment; and 3) complete patient-reported outcome measures at baseline and 6-weeks and 3-, 6-, and 12-months post-randomization.",[27],"Patellofemoral Pain",[29,30,31,32,33],"Physical Therapy","Military","Service members","Rehabilitation","Clinical Practice Guidelines","RECRUITING","2026-04-30",{"date":37,"type":38},"2026-05-06","ACTUAL",{"date":40,"type":38},"2025-08-22",{"date":42,"type":21},"2028-09-29",{"name":44,"class":45},"Sara Gorczynski, PT, DPT","FED",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100477764","vibration-on-patellofemoral-joint-pain-after-aclr-100477764","NCT05501210","Vibration on Patellofemoral Joint Pain After ACLR","The Effect of Whole-Body Vibration on Patellofemoral Joint Pain After Anterior Cruciate Ligament Reconstruction","Inclusion Criteria:\n\n1. Age between 18 to 60\n2. Unilateral ACLR\n3. Persisting PFJ pain\n4. Isolated symptomatic site or pathology\n\nExclusion Criteria:\n\n1. Age \\> 60\n2. Bilateral ACLR\n3. Revision ACLR\n4. Any rheumatological diseases\n5. Previous contralateral knee injury\n6. Any knee osteoarthritis","60 Years",{"count":56,"type":21},50,[24],"Anterior cruciate ligament (ACL) injury is a prevailing problem among sports participants, especially in non-contact sports. Studies have reported that 70-84% of ACL injuries are non-contact in nature, and movements like changing in direction while running, cutting and pivoting on a planted foot have resulted in a majority of ACL injuries. Even after ACL reconstruction (ACLR) surgeries, study has reported a 30-50% prevalence of developing patellofemoral joint (PFJ) pain in 1-2 years post-operation. Whole body vibration (WBV) therapy has been gaining attention as an effective method of training in recent years. It has been proved to have a positive effect on improving muscle strength, muscle activities, muscle power and loading during drop jump. Though duration of WBV may differ according to the effect of interest, several studies have had positive results with a 8 week WBV therapy in increasing muscle strength, proprioception, and post-ACLR knee functions. Further investigation on the underlying mechanism and possible application are to be continued to explore more possibilities with the WBV therapy.",[60,61,62,27],"Anterior Cruciate Ligament Injuries","Anterior Cruciate Ligament Rupture","Anterior Cruciate Ligament Tear",[64,65,66,67],"ACLR","Patellofemoral joint","Whole Body vibration","Knee function","2026-03-17",{"date":70,"type":38},"2026-03-18",{"date":72,"type":38},"2022-03-01",{"date":74,"type":21},"2029-09-01",{"name":76,"class":77},"Chinese University of Hong Kong","OTHER",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":18,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":46},"100461159","limited-ankle-dorsiflexion-and-effect-on-single-limb-squats-in-individuals-with-patellofemoral-pain-100461159","NCT05285007","Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain","Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain: Interventions and Outcomes in a Randomized Clinical Trial","Inclusion Criteria:\n\n* History of active Patellofemoral Pain for at least 6 months\n* No clinic based therapeutic interventions for a 6-month period prior to testing\n* Females aged 18-59 years' old\n* Limited ankle dorsiflexion as noted by \\\u003C45degs using the weight bearing lunge test\n\nExclusion Criteria:\n\n* History of musculoskeletal surgery or fractures on the tested leg or lumbar spine that could affect their biomechanics during the study\n* History of soft tissue or skeletal abnormalities in the tested limb\n* Current knee effusion\n* Resting pain greater than 5\u002F10",true,"FEMALE","59 Years",{"count":89,"type":21},60,[24],"The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral\u002FKnee Pain population.",[27],"2026-02-02",{"date":95,"type":38},"2026-02-04",{"date":97,"type":38},"2022-03-02",{"date":99,"type":21},"2026-05",{"name":101,"class":77},"Loma Linda University",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":126},"100555820","emovi-3d-knee-assessment-device-intervention-for-operational-readiness-100555820","NCT06517056","Emovi 3D Knee Assessment Device Intervention for Operational Readiness","Objective Dynamic and 3D Knee Assessment Medical Device to Improve Recovery and Accelerate Return to Readiness in Service Members With Knee Pain","Inclusion Criteria:\n\n* Age 18-50\n* Active Duty Service Member stationed at Fort Liberty and Schofield Barracks\n* Diagnosis of patellofemoral pain (ICD-10 codes: M25.2 (pain in unspecified knee), M25.561 (pain in right knee), and M25.562 (pain in left knee)\n\nExclusion Criteria:\n\n* Pregnancy\n* Known to be leaving that duty station within next 3 months\n* Concurrent lower limb injuries (examples include but are not limited to ankle sprain or HS strain)\n* Previous knee surgery\n* History of traumatic knee injury, such as a ligament tear or meniscal tear\n* Presence of rheumatoid or neurological disease","50 Years",{"count":111,"type":21},180,[24],"This is a randomized clinical trial investigating the use of the Emovi Knee Kinesiography information in the treatment of anterior knee pain in physical therapy.",[27,115],"Patellofemoral Pain Syndrome",[27,115],"2025-07-10",{"date":119,"type":38},"2025-07-16",{"date":121,"type":38},"2024-10-24",{"date":123,"type":21},"2025-10",{"name":125,"class":45},"Womack Army Medical Center",2,{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":22,"phases":138,"briefSummary":139,"conditions":140,"keywords":141,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":46},"100554922","effects-of-percutaneous-neuromouldation-of-the-saphenous-nerve-in-patients-with-patellofemoral-pain-100554922","NCT06505382","Effects of Percutaneous Neuromouldation of the Saphenous Nerve in Patients With Patellofemoral Pain","Effects of Ultrasound-Guided Percutaneous Neuromodulation of the Saphenous Nerve for Pain Management and Functionality in Patellofemoral Pain Syndrome Patients: A Single-Blind Randomized Controlled Trial","PNMSNPFP","Inclusion Criteria:\n\n* Be 18 years or older.\n* Knee pain in the anterior aspect or around the patella for at least 1 month, exacerbated by activities such as squatting, stair climbing, or prolonged sitting.\n* Patients experiencing difficulty participating in sports due to pain.\n\nExclusion Criteria:\n\n* Previous surgical intervention on the painful knee.\n* Previous diagnosed knee pathology.\n* Recent trauma or acute injury to the knee that may have led to the development of pain.\n* Antiplatelet or anticoagulant therapy.\n* Bilateral symptoms.\n* Pain attributed to hypersensitivity of any peripheral nerve of the lower limbs or a positive electromyographic test.\n* Lumbar spine pathologies (herniated disc, protrusion, etc.).\n* Use of medications such as opioids or those with knee pain as a side effect.\n* Belonephobia or any condition where percutaneous needle insertion is contraindicated.\n* Pregnancy.","80 Years",{"count":137,"type":21},24,[24],"The knee is a common source of musculoskeletal pain, with patellofemoral pain (PFP) standing out due to its high prevalence. This pain, frequent in adolescents and athletes, significantly impacts the quality of life by hindering daily activities such as climbing stairs and sitting for extended periods. Percutaneous neuromodulation of the saphenous nerve (PNM) emerges as a promising therapeutic approach in physiotherapy to alleviate these symptoms.\n\nA randomized controlled clinical trial is proposed in adults with PFP. Participants will be divided into two groups: one will receive PNM of the saphenous nerve, while the other will be a control group receiving puncture without electrical stimulation. Pain, extension strength, and knee range of motion will be evaluated before and after the intervention using the AKPS scale. Three sessions will be conducted with specific intervals, and a follow-up assessment will be performed three months later.",[27],[142,143,144,145,146],"ultrasound-guided percutaneous neuromodulation","saphenous nerve","pain","functionality","femoropatellar pain","NOT_YET_RECRUITING","2024-07-14",{"date":150,"type":38},"2024-07-17",{"date":152,"type":21},"2024-09-30",{"date":154,"type":21},"2025-06-30",{"name":156,"class":77},"University of Alcala"]