[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pathologic-fracture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pathologic-fracture":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,69,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100427150","illuminoss-photodynamic-bone-stabilization-system-for-the-treatment-of-impending-and-actual-pelvis-fractures-100427150",false,"NCT04842266","IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures","A Prospective Study of the IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pathological Fractures in the Pelvis From Metastatic Bone Disease or Geriatric Pelvic Fractures","Inclusion criteria:\n\nPatients are being targeted because they have already agreed to the undergo the IlluminOss Pelvic Implant for standard clinical care. It is a decision made by the treating surgeon separately from research and prior to mention of the study.\n\n1. Patient is a skeletally mature patient 21 years of age or older (closed epiphyseal plates) who receiving the FDA-approved IlluminOss Pelvic Implant\n2. IlluminOss Pelvic Implant is intended to treat pain due to impending or actual non-displaced or minimally displaced pathologic fractures of the pelvis secondary to metastatic malignancy, multiple myeloma, lymphoma, or radiation osteitis or a pelvic fragility fracture in a geriatric patients (age 65 or older)\n3. VAS Pain Score ≥ 30 on 0 to 100 scale\n\nExclusion criteria:\n\n1. Patient is uncooperative, or patient incapable of following directions (for example, as a consequence of a neurological or psychiatric disorder)\n2. Patient is a prisoner\n3. Patient is deemed surgically unfit by the medical oncology service","ALL","21 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","The aim of this project is to assess the effectiveness of the IlluminOss pelvic implants in patients with pelvic metastatic disease presenting with pain, risk of pathologic fracture, non-displaced or minimally displaced pathologic fracture of the pelvis, and geriatric patients with pelvic fragility fractures. Results from this study will be used to confirm preliminary clinically and possibly statistically significant reductions in pain and improvements in function among these patients.",[24,25,26],"Cancer Metastatic","Trauma","Pathologic Fracture","RECRUITING","2026-01-14",{"date":30,"type":31},"2026-01-16","ACTUAL",{"date":33,"type":31},"2021-11-18",{"date":35,"type":20},"2027-12",{"name":37,"class":38},"Massachusetts General Hospital","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":49,"conditions":50,"keywords":53,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":39},"100502684","metastatic-pathologic-fractures-short-term-results-100502684","NCT05825456","Metastatic Pathologic Fractures, Short Term Results","Metastatic Pathologic Fractures: Short Term Results of Endoprosthetic Reconstruction, Intramedullary Nail and Open Reduction Internal Fixation","Inclusion Criteria:\n\n* metastatic pathologic fracture\n* operated via endoprosthesis, intramedullary nail or plate \\& screws\n\nExclusion Criteria:\n\n* primary bone tumor\n* conservative management\n* neuromuscular disease\n* periprosthetic fractures\n* less than 1 month follow up",{"count":48,"type":20},200,"This is a single center prospective study to compare the short term results of prosthesis, nail and plate-screw surgeries for metastatic pathologic fractures.",[26,51,52],"Bone Metastases","Metastatic Cancer",[54,55,56,57,58,59],"bone metastasis","pathologic fracture","endoprosthetic reconstruction","intramedullary nailing","open reduction internal fixation","plate and screws","2025-03-01",{"date":62,"type":31},"2025-03-05",{"date":64,"type":31},"2022-01-01",{"date":66,"type":20},"2026-01-01",{"name":68,"class":38},"Ankara University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":16,"minAge":78,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":91,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":102,"locationsCount":39},"100558666","study-comparing-the-pathkeeper-system-for-pedicle-screw-positioning-in-spine-surgery-with-traditional-care-100558666","NCT06554093","Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care","A Prospective, Dual Canter, Double Armed, Open Label, Clinical Study to Evaluate the Performance of the PathKeeper System for Pedicle Screw Positioning in Spine Surgery","PKSforPSP","Inclusion Criteria:\n\n* Men and women\n* 16 and above years old\n* Patients who are about to undergo open, instrumented spinal surgery\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Men and women\n* 16 and above years old\n* Patients who are about to undergo open, instrumented spinal surgery\n* Signed informed consent form",true,"16 Years",{"count":80,"type":20},32,"INTERVENTIONAL",[83],"NA","The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question\\[s\\]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS) with control arm",[86,87,88,89,90,26],"Scoliosis","Scoliosis; Adolescence","Scoliosis Kyphosis","Scoliosis Lumbar Region","Scoliosis Thoracic Region",[92,93,94],"fusion","screw positioning","screw insertion","NOT_YET_RECRUITING","2025-02-03",{"date":98,"type":31},"2025-02-05",{"date":100,"type":20},"2025-10-30",{"date":100,"type":20},{"name":103,"class":104},"Deep Health Ltd.","INDUSTRY",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":16,"minAge":113,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":81,"phases":116,"briefSummary":117,"conditions":118,"keywords":119,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":4},"100577601","performance-and-safety-of-the-innofix-screw-if25-100577601","NCT06800417","Performance and Safety of the Innofix® Screw (IF25)","Performance and Safety of the Innofix® Screw as Part of Stabilization of a Non-displaced Pathologic Fracture (Complete or Impending) of the Pelvic Bone of Cancer Patients by Mini-invasive Percutaneous Fixation by Internal Cemented Screw","IF25","Inclusion Criteria:\n\n* The patient is 18 years old or more\n* The patient is a cancer patient\n* The patient needs a stabilization of a non-displaced pathologic fracture (complete or impending) of the pelvic bone\n* The patient is symptomatic with musculoskeletal pain exacerbated during movement or weight bearing\n* The patient has been informed and he has signed the informed consent\n* The patient must be willing and able to comply with all study requirements including follow-up visits and radiographic assessments\n* The patient is affiliated with the French social security system\n\nExclusion Criteria:\n\n* The patient has got a displaced fracture or an unstable fracture justifying conventional surgical fixation\n* The patient is a pregnant woman or considered getting pregnant during its investigation participation\n* The patient presents medical conditions that could have an impact on the clinical investigation (under responsibility of the investigator)\n* The patient has got one or more contraindications to general anaesthesia\n* The patient has got an insufficient bone strength (severe osteoporosis, local infection, or tumor osteolysis) precluding a correct and long-term fixation\n* The use of the InnoFix® screw can interfere with anatomical structures or physiological performances\n* The patient has got an insufficient tissue coverage at the surgical site\n* The patient has got a sepsis, fever, subcutaneous or cutaneous infection on the implantation way, deep abscess in contact with the fracture site\n* The patient has got a mental or neuromuscular disorder that may cause fixation failure or postoperative complications\n* The patient is allergic and\u002For hypersensitive to a component of the InnoFix® modules, of the InnoTool™ instruments and to the used cement\n* The patient has got a haemostasis disorder ((INR \\>1.5, platelets \\\u003C50x109\u002FL)\n* The patient participates to another clinical investigation\n* The patient's life expectancy is lower than 6 months\n* The patient is under guardianship, curatorship or legal protection\n* The patient is deprived of liberty by a judicial or administrative decision","18 Years",{"count":115,"type":20},34,[83],"The purpose of this clinical investigation is to collect data about the safety and the performances of the InnoFix® screw : Clinical performances (Pain reduction due to the fracture treatment, maintenance of the stabilizaton of the treated fracture and mobility improvement) \u002F Technical performances (Percutaneous implantation by mini-invasive approach, Efficiency of percutaneous implementation and efficiency of percuatneous cementing) \u002F Safety performances (Preservation of the screw stability after implantation and preservation of the screw integrity after implantation). The safety and performance data about the InnoFix® screw will be used to obtain their CE marking according to the regulation (EU) 2017\u002F745.\n\nThe principal objective of this clinical investigation is to assess the postoperative reduction in pain level of the patient at 6 weeks follow-up.",[26],[120,121,122],"FICS","Pelvis","Cancer","2025-01-29",{"date":125,"type":31},"2025-01-30",{"date":127,"type":20},"2025-05",{"date":129,"type":20},"2026-05",{"name":131,"class":104},"Innoprod Medical"]